David S. Warner

Publications

• ApoE Mimetic Ameliorates Motor Deficit and Tissue Damage in Rat Spinal Cord Injury
  Journal of Neuroscience Research. Jul, 2014  |   Pubmed ID: 24633884
• Anesthetic Neuroprotection: Antecedents and An Appraisal of Preclinical and Clinical Data Quality
  Current Pharmaceutical Design. Feb, 2014  |   Pubmed ID: 24502575
• Volatile Anesthetic Sedation During Therapeutic Hypothermia After Cardiac Arrest in the ICU: a Journey of a Thousand Miles Begins with a Single Step
  Critical Care Medicine. Feb, 2014  |   Pubmed ID: 24434469
• Mr. Piano Man: Reflections on the Life of Physician, Scientist, and Humanitarian, William L. Young, MD (1954-2013)
  Journal of Neurosurgical Anesthesiology. Jan, 2014  |   Pubmed ID: 24394583
• Metalloporphyrins As Therapeutic Catalytic Oxidoreductants in Central Nervous System Disorders
  Antioxidants & Redox Signaling. May, 2014  |   Pubmed ID: 23706004
• Drowning Resuscitation Requires Another State of Mind
  Resuscitation. Nov, 2013  |   Pubmed ID: 24036192
• Differential Coordination Demands in Fe Versus Mn Water-soluble Cationic Metalloporphyrins Translate into Remarkably Different Aqueous Redox Chemistry and Biology
  Inorganic Chemistry. May, 2013  |   Pubmed ID: 23646875
• Protective Astrogenesis from the SVZ Niche After Injury is Controlled by Notch Modulator Thbs4
  Nature. May, 2013  |   Pubmed ID: 23615612
• Comprehensive Pharmacokinetic Studies and Oral Bioavailability of Two Mn Porphyrin-based SOD Mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+
  Free Radical Biology & Medicine. May, 2013  |   Pubmed ID: 23328731
• Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-based Redox Modulators
  Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. 2013  |   Pubmed ID: 23075911
• Lack of Evidence for a Remote Effect of Renal Ischemia/reperfusion Acute Kidney Injury on Outcome from Temporary Focal Cerebral Ischemia in the Rat
  Journal of Cardiothoracic and Vascular Anesthesia. Feb, 2013  |   Pubmed ID: 22841525
• Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage
  Anesthesiology. Dec, 2012  |   Pubmed ID: 23143806
• Brain Resuscitation in the Drowning Victim
  Neurocritical Care. Dec, 2012  |   Pubmed ID: 22956050
• A New SOD Mimic, Mn(III) Ortho N-butoxyethylpyridylporphyrin, Combines Superb Potency and Lipophilicity with Low Toxicity
  Free Radical Biology & Medicine. May, 2012  |   Pubmed ID: 22336516
• Statins Improve Outcome in Murine Models of Intracranial Hemorrhage and Traumatic Brain Injury: A Translational Approach
  Journal of Neurotrauma. Jan, 2012  |   Pubmed ID: 22233347
• Neuroprotective Efficacy from a Lipophilic Redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2011  |   Pubmed ID: 21652782
• Methoxy-derivatization of Alkyl Chains Increases the in Vivo Efficacy of Cationic Mn Porphyrins. Synthesis, Characterization, SOD-like Activity, and SOD-deficient E. Coli Study of Meta Mn(III) N-methoxyalkylpyridylporphyrins
  Dalton Transactions (Cambridge, England : 2003). Apr, 2011  |   Pubmed ID: 21384047
• Pharmacologically Augmented S-nitrosylated Hemoglobin Improves Recovery from Murine Subarachnoid Hemorrhage
  Stroke; a Journal of Cerebral Circulation. Feb, 2011  |   Pubmed ID: 21193749
• Adenosine-induced Transient Asystole for Intracranial Aneurysm Surgery: a Retrospective Review
  Journal of Neurosurgical Anesthesiology. Jan, 2011  |   Pubmed ID: 20706138
• Development of a Simplified Spinal Cord Ischemia Model in Mice
  Journal of Neuroscience Methods. Jun, 2010  |   Pubmed ID: 20394775
• Metalloporphyrin Antioxidants Ameliorate Normal Tissue Radiation Damage in Rat Brain
  International Journal of Radiation Biology. Feb, 2010  |   Pubmed ID: 20148700
• Simvastatin Treatment Duration and Cognitive Preservation in Experimental Subarachnoid Hemorrhage
  Journal of Neurosurgical Anesthesiology. Oct, 2009  |   Pubmed ID: 19955895
• Long-term Neuroprotection from a Potent Redox-modulating Metalloporphyrin in the Rat
  Free Radical Biology & Medicine. Oct, 2009  |   Pubmed ID: 19631268
• Oxygen and Glucose Deprivation in an Organotypic Hippocampal Slice Model of the Developing Rat Brain: the Effects on N-methyl-D-aspartate Subunit Composition
  Anesthesia and Analgesia. Jul, 2009  |   Pubmed ID: 19535712
• Drowning: a Cry for Help
  Anesthesiology. Jun, 2009  |   Pubmed ID: 19417605
• Effect of Lipophilicity of Mn (III) Ortho N-alkylpyridyl- and Diortho N, N'-diethylimidazolylporphyrins in Two In-vitro Models of Oxygen and Glucose Deprivation-induced Neuronal Death
  Free Radical Research. Apr, 2009  |   Pubmed ID: 19259881
• Perioperative Hypothermia: Use and Therapeutic Implications
  Journal of Neurotrauma. Mar, 2009  |   Pubmed ID: 19231924
• Filling in the Blanks
  Anesthesiology. Jan, 2009  |   Pubmed ID: 19104163
• 2008 in Review: Advancing Medicine in Anesthesiology
  Anesthesiology. Dec, 2008  |   Pubmed ID: 19034092
• The Use of S100B As a Biomarker in Subarachnoid Hemorrhage: Clarity in Its Promise and Limits
  Critical Care Medicine. Aug, 2008  |   Pubmed ID: 18664797
• Long-term Cognitive Dysfunction Following Experimental Subarachnoid Hemorrhage: New Perspectives
  Experimental Neurology. Oct, 2008  |   Pubmed ID: 18625221
• Cerebral Ischemia/stroke and Small Ubiquitin-like Modifier (SUMO) Conjugation--a New Target for Therapeutic Intervention?
  Journal of Neurochemistry. Aug, 2008  |   Pubmed ID: 18410505
• Transient Focal Cerebral Ischemia Induces a Dramatic Activation of Small Ubiquitin-like Modifier Conjugation
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2008  |   Pubmed ID: 18167501
• Statins in Acute Brain Injury: Getting the Cart Before the Horse
  Neurocritical Care. 2008  |   Pubmed ID: 18094941
• Preclinical Models of Intracerebral Hemorrhage: a Translational Perspective
  Neurocritical Care. 2008  |   Pubmed ID: 18058257
• Transient Global Cerebral Ischemia Induces a Massive Increase in Protein Sumoylation
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2008  |   Pubmed ID: 17565359
• Hypertonic Saline for Craniotomy?
  Anesthesiology. Nov, 2007  |   Pubmed ID: 18073540
• Simvastatin and Atorvastatin Improve Behavioral Outcome, Reduce Hippocampal Degeneration, and Improve Cerebral Blood Flow After Experimental Traumatic Brain Injury
  Experimental Neurology. Jul, 2007  |   Pubmed ID: 17521631
• Superparamagnetic Iron Oxide Labeling and Transplantation of Adipose-derived Stem Cells in Middle Cerebral Artery Occlusion-injured Mice
  AJR. American Journal of Roentgenology. Apr, 2007  |   Pubmed ID: 17377054
• Isoflurane Provides Long-term Protection Against Focal Cerebral Ischemia in the Rat
  Anesthesiology. Jan, 2007  |   Pubmed ID: 17197850
• Dissociation Between Vasospasm and Functional Improvement in a Murine Model of Subarachnoid Hemorrhage
  Neurosurgical Focus. 2006  |   Pubmed ID: 17029343
• NMDA-induced Apoptosis in Mixed Neuronal/glial Cortical Cell Cultures: the Effects of Isoflurane and Dizocilpine
  Journal of Neurosurgical Anesthesiology. Oct, 2006  |   Pubmed ID: 17006121
• Levetiracetam is Neuroprotective in Murine Models of Closed Head Injury and Subarachnoid Hemorrhage
  Neurocritical Care. 2006  |   Pubmed ID: 16960300
• Selective Gamma-aminobutyric Acid Type A Receptor Antagonism Reverses Isoflurane Ischemic Neuroprotection
  Anesthesiology. Jul, 2006  |   Pubmed ID: 16809998
• Cardiac Glycosides Provide Neuroprotection Against Ischemic Stroke: Discovery by a Brain Slice-based Compound Screening Platform
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006  |   Pubmed ID: 16793926
• Induction of Hypothermia After Intraoperative Hypoxic Brain Insult
  Anesthesia and Analgesia. Jul, 2006  |   Pubmed ID: 16790649
• Changing Outcome from Aneurysmal Subarachnoid Hemorrhage: Another Step Closer
  Anesthesiology. Apr, 2006  |   Pubmed ID: 16571953
• A Novel ApoE-derived Therapeutic Reduces Vasospasm and Improves Outcome in a Murine Model of Subarachnoid Hemorrhage
  Neurocritical Care. 2006  |   Pubmed ID: 16498192
• A Comparison of Hyperbaric Oxygen Versus Hypoxic Cerebral Preconditioning in Neonatal Rats
  Brain Research. Feb, 2006  |   Pubmed ID: 16458861
• Effects of a Manganese (III) Porphyrin Catalytic Antioxidant in a Mouse Closed Head Injury Model
  European Journal of Pharmacology. Feb, 2006  |   Pubmed ID: 16455070
• The Effect of Age on Sciatic Nerve Block Duration
  Anesthesia and Analgesia. Feb, 2006  |   Pubmed ID: 16428567
• Peripheral Nerve Block Techniques for Ambulatory Surgery
  Anesthesia and Analgesia. Dec, 2005  |   Pubmed ID: 16301239
• Magnesium Neuroprotection is Limited in Humans with Acute Brain Injury
  Neurocritical Care. 2005  |   Pubmed ID: 16159086
• Isoflurane-induced Neuronal Degeneration: an Evaluation in Organotypic Hippocampal Slice Cultures
  Anesthesia and Analgesia. Sep, 2005  |   Pubmed ID: 16115969
• Simvastatin Reduces Vasospasm After Aneurysmal Subarachnoid Hemorrhage: Results of a Pilot Randomized Clinical Trial
  Stroke; a Journal of Cerebral Circulation. Sep, 2005  |   Pubmed ID: 16051891
• A Retrospective Analysis of a Remifentanil/propofol General Anesthetic for Craniotomy Before Awake Functional Brain Mapping
  Anesthesia and Analgesia. Aug, 2005  |   Pubmed ID: 16037168
• Intrathecal Administration of a Novel ApoE-derived Therapeutic Peptide Improves Outcome Following Perinatal Hypoxic-ischemic Injury
  Neuroscience Letters. Jun, 2005  |   Pubmed ID: 15896489
• Analysis of the Brain Bioavailability of Peripherally Administered Magnesium Sulfate: A Study in Humans with Acute Brain Injury Undergoing Prolonged Induced Hypermagnesemia
  Critical Care Medicine. Mar, 2005  |   Pubmed ID: 15753761
• A Novel Therapeutic Derived from Apolipoprotein E Reduces Brain Inflammation and Improves Outcome After Closed Head Injury
  Experimental Neurology. Mar, 2005  |   Pubmed ID: 15698624
• Apoptosis is Not Enhanced in Primary Mixed Neuronal/glial Cultures Protected by Isoflurane Against N-methyl-D-aspartate Excitotoxicity
  Anesthesia and Analgesia. Dec, 2004  |   Pubmed ID: 15562059
• Anesthetics Provide Limited but Real Protection Against Acute Brain Injury
  Journal of Neurosurgical Anesthesiology. Oct, 2004  |   Pubmed ID: 15557838
• Changes in Magnetization Transfer MRI Correlate with Spreading Depression-induced Astroglial Reactivity and Increased Protein Expression in Mice
  AJR. American Journal of Roentgenology. Dec, 2004  |   Pubmed ID: 15547231
• Treatment of Traumatic Brain Injury: One Size Does Not Fit All
  Anesthesia and Analgesia. Oct, 2004  |   Pubmed ID: 15385377
• Intraischemic Nitrous Oxide Alters Neither Neurologic nor Histologic Outcome: a Comparison with Dizocilpine
  Anesthesia and Analgesia. Sep, 2004  |   Pubmed ID: 15333428
• Oxidants, Antioxidants and the Ischemic Brain
  The Journal of Experimental Biology. Aug, 2004  |   Pubmed ID: 15299043
• Mouse Spinal Cord Compression Injury is Ameliorated by Intrathecal Cationic Manganese(III) Porphyrin Catalytic Antioxidant Therapy
  Neuroscience Letters. Aug, 2004  |   Pubmed ID: 15276251
• A No-laminectomy Spinal Cord Compression Injury Model in Mice
  Journal of Neurotrauma. May, 2004  |   Pubmed ID: 15165367
• Effects of Isoflurane Versus Fentanyl-nitrous Oxide Anesthesia on Long-term Outcome from Severe Forebrain Ischemia in the Rat
  Anesthesiology. May, 2004  |   Pubmed ID: 15114213
• Perioperative Neuroprotection: Are We Asking the Right Questions?
  Anesthesia and Analgesia. Mar, 2004  |   Pubmed ID: 14980898
• Pharmacologic Protection from Ischemic Neuronal Injury
  Journal of Neurosurgical Anesthesiology. Jan, 2004  |   Pubmed ID: 14676578
• Apolipoprotein E Protects Against Oxidative Stress in Mixed Neuronal-glial Cell Cultures by Reducing Glutamate Toxicity
  Neurochemistry International. Jan, 2004  |   Pubmed ID: 12971913
• Severe Hypotension is Not Essential for Isoflurane Neuroprotection Against Forebrain Ischemia in Mice
  Anesthesiology. Nov, 2003  |   Pubmed ID: 14576552
• Altered Perceptions After Upper and Lower Extremity Blocks: an Initial Investigation
  Regional Anesthesia and Pain Medicine. Sep-Oct, 2003  |   Pubmed ID: 14556134
• The Neuroprotective Effect of Xenon Administration During Transient Middle Cerebral Artery Occlusion in Mice
  Anesthesiology. Oct, 2003  |   Pubmed ID: 14508320
• APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response
  The Journal of Biological Chemistry. Dec, 2003  |   Pubmed ID: 14507923
• Gamma-Aminobutyric Acid-A Receptors Contribute to Isoflurane Neuroprotection in Organotypic Hippocampal Cultures
  Anesthesia and Analgesia. Aug, 2003  |   Pubmed ID: 12873954
• The Difficulties of Ambulatory Interscalene and Intra-articular Infusions for Rotator Cuff Surgery: a Preliminary Report
  Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie. Mar, 2003  |   Pubmed ID: 12620950
• Possible Role for Vascular Cell Proliferation in Cerebral Vasospasm After Subarachnoid Hemorrhage
  Stroke; a Journal of Cerebral Circulation. Feb, 2003  |   Pubmed ID: 12574555
• Catalytic Antioxidants As Novel Pharmacologic Approaches to Treatment of Ischemic Brain Injury
  Drug News & Perspectives. Dec, 2002  |   Pubmed ID: 12677251
• Hemodynamic Effects of Metalloporphyrin Catalytic Antioxidants: Structure-activity Relationships and Species Specificity
  Free Radical Biology & Medicine. Dec, 2002  |   Pubmed ID: 12488134
• A Comparison of the Remifentanil and Fentanyl Adverse Effect Profile in a Multicenter Phase IV Study
  Journal of Clinical Anesthesia. Nov, 2002  |   Pubmed ID: 12477583
• Simvastatin Increases Endothelial Nitric Oxide Synthase and Ameliorates Cerebral Vasospasm Resulting from Subarachnoid Hemorrhage
  Stroke; a Journal of Cerebral Circulation. Dec, 2002  |   Pubmed ID: 12468796
• Apolipoprotein E Protects Against NMDA Excitotoxicity
  Neurobiology of Disease. Oct, 2002  |   Pubmed ID: 12460559
• Serum Von Willebrand Factor, Matrix Metalloproteinase-9, and Vascular Endothelial Growth Factor Levels Predict the Onset of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage
  Neurosurgery. Nov, 2002  |   Pubmed ID: 12383357
• A Catalytic Antioxidant (AEOL 10150) Attenuates Expression of Inflammatory Genes in Stroke
  Free Radical Biology & Medicine. Oct, 2002  |   Pubmed ID: 12374626
• Paravertebral Somatic Nerve Block Compared with Peripheral Nerve Blocks for Outpatient Inguinal Herniorrhaphy
  Regional Anesthesia and Pain Medicine. Sep-Oct, 2002  |   Pubmed ID: 12373694
• Effects of Metalloporphyrin Catalytic Antioxidants in Experimental Brain Ischemia
  Free Radical Biology & Medicine. Oct, 2002  |   Pubmed ID: 12361805
• Attenuation of Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice Overexpressing Extracellular Superoxide Dismutase
  Stroke; a Journal of Cerebral Circulation. Sep, 2002  |   Pubmed ID: 12215605
• Brain Oxygenation and Energy Metabolism: Part I-biological Function and Pathophysiology
  Neurosurgery. Aug, 2002  |   Pubmed ID: 12182767
• Allopregnanolone Attenuates N-methyl-D-aspartate-induced Excitotoxicity and Apoptosis in the Human NT2 Cell Line in Culture
  Neuroscience Letters. Aug, 2002  |   Pubmed ID: 12123853
• Mouse Model of Subarachnoid Hemorrhage Associated Cerebral Vasospasm: Methodological Analysis
  Neurological Research. Jul, 2002  |   Pubmed ID: 12117325
• Differential Cerebral Gene Expression During Cardiopulmonary Bypass in the Rat: Evidence for Apoptosis?
  Anesthesia and Analgesia. Jun, 2002  |   Pubmed ID: 12031994
• Pharmacological Correction of Hypothermic P(50) Shift Does Not Alter Outcome from Focal Cerebral Ischemia in Rats
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2002  |   Pubmed ID: 11959653
• A Randomized, Double-blind Comparison of Ondansetron Versus Placebo for Prevention of Nausea and Vomiting After Infratentorial Craniotomy
  Journal of Neurosurgical Anesthesiology. Apr, 2002  |   Pubmed ID: 11907389
• Apolipoprotein E Affects the Central Nervous System Response to Injury and the Development of Cerebral Edema
  Annals of Neurology. Jan, 2002  |   Pubmed ID: 11782990
• Peripheral Nerve Blockade with Long-acting Local Anesthetics: a Survey of the Society for Ambulatory Anesthesia
  Anesthesia and Analgesia. Jan, 2002  |   Pubmed ID: 11772803
• Ambulatory Discharge After Long-acting Peripheral Nerve Blockade: 2382 Blocks with Ropivacaine
  Anesthesia and Analgesia. Jan, 2002  |   Pubmed ID: 11772802