David Cribbs

Publications

• Delivery of a DNA Vaccine for Alzheimer's Disease by Electroporation Versus Gene Gun Generates Potent and Similar Immune Responses
  Neuro-degenerative Diseases. Feb, 2012  |   Pubmed ID: 22301697
• Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal β-catenin Pathway Function in an Alzheimer's Disease Model
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2011  |   Pubmed ID: 22095718
• Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
  PloS One. 2011  |   Pubmed ID: 22046234
• Frontal Cortex Neuropathology in Dementia Pugilistica
  Journal of Neurotrauma. Oct, 2011  |   Pubmed ID: 22017610
• Therapeutic Modulation of Cerebral Microhemorrhage in a Mouse Model of Cerebral Amyloid Angiopathy
  Stroke; a Journal of Cerebral Circulation. Nov, 2011  |   Pubmed ID: 21903962
• Loss of Muscarinic M1 Receptor Exacerbates Alzheimer's Disease-like Pathology and Cognitive Decline
  The American Journal of Pathology. Aug, 2011  |   Pubmed ID: 21704011
• Cancer-testis Antigen, BORIS Based Vaccine Delivered by Dendritic Cells is Extremely Effective Against a Very Aggressive and Highly Metastatic Mouse Mammary Carcinoma
  Cellular Immunology. 2011  |   Pubmed ID: 21641588
• An Amyloid β(42)-dependent Deficit in Anandamide Mobilization is Associated with Cognitive Dysfunction in Alzheimer's Disease
  Neurobiology of Aging. May, 2011  |   Pubmed ID: 21546126
• Restricted V Gene Usage and VH/VL Pairing of Mouse Humoral Response Against the N-terminal Immunodominant Epitope of the Amyloid β Peptide
  Molecular Immunology. Nov-Dec, 2010  |   Pubmed ID: 20970857
• Aging and Cerebrovascular Dysfunction: Contribution of Hypertension, Cerebral Amyloid Angiopathy, and Immunotherapy
  Annals of the New York Academy of Sciences. Oct, 2010  |   Pubmed ID: 20955427
• Anti-11[E]-pyroglutamate-modified Amyloid β Antibodies Cross-react with Other Pathological Aβ Species: Relevance for Immunotherapy
  Journal of Neuroimmunology. Dec, 2010  |   Pubmed ID: 20864186
• Reductions in Amyloid-beta-derived Neuroinflammation, with Minocycline, Restore Cognition but Do Not Significantly Affect Tau Hyperphosphorylation
  Journal of Alzheimer's Disease : JAD. 2010  |   Pubmed ID: 20555131
• Low Concentrations of Anti-Aβ Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology
  Human Gene Therapy. Nov, 2010  |   Pubmed ID: 20528468
• Linear and Conformation Specific Antibodies in Aged Beagles After Prolonged Vaccination with Aggregated Abeta
  Neurobiology of Disease. Sep, 2010  |   Pubmed ID: 20451612
• Abeta DNA Vaccination for Alzheimer's Disease: Focus on Disease Prevention
  CNS & Neurological Disorders Drug Targets. Apr, 2010  |   Pubmed ID: 20205639
• Immunization with Amyloid-beta Attenuates Inclusion Body Myositis-like Myopathology and Motor Impairment in a Transgenic Mouse Model
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009  |   Pubmed ID: 19439591
• A Fibril-specific, Conformation-dependent Antibody Recognizes a Subset of Abeta Plaques in Alzheimer Disease, Down Syndrome and Tg2576 Transgenic Mouse Brain
  Acta Neuropathologica. Oct, 2009  |   Pubmed ID: 19360426
• Active and Passive Abeta-immunotherapy: Preclinical and Clinical Studies and Future Directions: Part II
  CNS & Neurological Disorders Drug Targets. Apr, 2009  |   Pubmed ID: 19355929
• Active and Passive Abeta-immunotherapy: Preclinical and Clinical Studies and Future Directions: Part I
  CNS & Neurological Disorders Drug Targets. Mar, 2009  |   Pubmed ID: 19275632
• Blocking Abeta42 Accumulation Delays the Onset and Progression of Tau Pathology Via the C Terminus of Heat Shock Protein70-interacting Protein: a Mechanistic Link Between Abeta and Tau Pathology
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008  |   Pubmed ID: 19020010
• DNA Epitope Vaccine Containing Complement Component C3d Enhances Anti-amyloid-beta Antibody Production and Polarizes the Immune Response Towards a Th2 Phenotype
  Journal of Neuroimmunology. Dec, 2008  |   Pubmed ID: 18838175
• Gene Expression Changes in the Course of Normal Brain Aging Are Sexually Dimorphic
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008  |   Pubmed ID: 18832152
• Mannan-Abeta28 Conjugate Prevents Abeta-plaque Deposition, but Increases Microhemorrhages in the Brains of Vaccinated Tg2576 (APPsw) Mice
  Journal of Neuroinflammation. 2008  |   Pubmed ID: 18823564
• Cross-regulatory Protein-protein Interactions Between Hox and Pax Transcription Factors
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008  |   Pubmed ID: 18755899
• Timing of Wingless Signalling Distinguishes Maxillary and Antennal Identities in Drosophila Melanogaster
  Development (Cambridge, England). Jul, 2008  |   Pubmed ID: 18508864
• Reducing AD-like Pathology in 3xTg-AD Mouse Model by DNA Epitope Vaccine - a Novel Immunotherapeutic Strategy
  PloS One. 2008  |   Pubmed ID: 18461171
• Exercise Alters the Immune Profile in Tg2576 Alzheimer Mice Toward a Response Coincident with Improved Cognitive Performance and Decreased Amyloid
  Journal of Neuroinflammation. 2008  |   Pubmed ID: 18400101
• A Two-year Study with Fibrillar Beta-amyloid (Abeta) Immunization in Aged Canines: Effects on Cognitive Function and Brain Abeta
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008  |   Pubmed ID: 18385314
• Amyloid-beta Peptide Binds to Microtubule-associated Protein 1B (MAP1B)
  Neurochemistry International. May, 2008  |   Pubmed ID: 18079022
• Immunostimulant Adjuvant Patch Enhances Humoral and Cellular Immune Responses to DNA Immunization
  DNA and Cell Biology. Jan, 2008  |   Pubmed ID: 17961074
• Experimental Investigation of Antibody-mediated Clearance Mechanisms of Amyloid-beta in CNS of Tg-SwDI Transgenic Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2007  |   Pubmed ID: 18057195
• Alzheimer's Disease Peptide Epitope Vaccine Reduces Insoluble but Not Soluble/oligomeric Abeta Species in Amyloid Precursor Protein Transgenic Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2007  |   Pubmed ID: 18003852
• Phagocytosis of Amyloid-beta and Inflammation: Two Faces of Innate Immunity in Alzheimer's Disease
  Journal of Alzheimer's Disease : JAD. Jul, 2007  |   Pubmed ID: 17656824
• Anti-A Beta 1-11 Antibody Binds to Different Beta-amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers
  The Journal of Biological Chemistry. Aug, 2007  |   Pubmed ID: 17545160
• Distinct Roles for Mediator Cdk8 Module Subunits in Drosophila Development
  The EMBO Journal. Feb, 2007  |   Pubmed ID: 17290221
• Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-testis Antigen, Brother of the Regulator of Imprinted Sites
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007  |   Pubmed ID: 17182597
• External Force-assisted Cell Positioning Inside Microfluidic Devices
  Biomedical Microdevices. Feb, 2007  |   Pubmed ID: 17091393
• Abeta-immunotherapy for Alzheimer's Disease Using Mannan-amyloid-Beta Peptide Immunoconjugates
  DNA and Cell Biology. Oct, 2006  |   Pubmed ID: 17132088
• Reduction of Soluble Abeta and Tau, but Not Soluble Abeta Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles
  The Journal of Biological Chemistry. Dec, 2006  |   Pubmed ID: 17056594
• Relapsing Polychondritis with Features of Dementia with Lewy Bodies
  Acta Neuropathologica. Aug, 2006  |   Pubmed ID: 16832629
• The Specification of a Highly Derived Arthropod Appendage, the Drosophila Labial Palps, Requires the Joint Action of Selectors and Signaling Pathways
  Development Genes and Evolution. Jul-Aug, 2006  |   Pubmed ID: 16773339
• Novel Approaches for Immunotherapeutic Intervention in Alzheimer's Disease
  Neurochemistry International. Jul, 2006  |   Pubmed ID: 16765487
• Antitumor Efficacy of DNA Vaccination to the Epigenetically Acting Tumor Promoting Transcription Factor BORIS and CD80 Molecular Adjuvant
  Journal of Cellular Biochemistry. Aug, 2006  |   Pubmed ID: 16741971
• Immunization with Fibrillar Abeta(1-42) in Young and Aged Canines: Antibody Generation and Characteristics, and Effects on CSF and Brain Abeta
  Vaccine. Apr, 2006  |   Pubmed ID: 16460841
• Prototype Alzheimer's Disease Epitope Vaccine Induced Strong Th2-type Anti-Abeta Antibody Response with Alum to Quil A Adjuvant Switch
  Vaccine. Mar, 2006  |   Pubmed ID: 16368167
• Novel Abeta Peptide Immunogens Modulate Plaque Pathology and Inflammation in a Murine Model of Alzheimer's Disease
  Journal of Neuroinflammation. 2005  |   Pubmed ID: 16332263
• A Microfluidic Culture Platform for CNS Axonal Injury, Regeneration and Transport
  Nature Methods. Aug, 2005  |   Pubmed ID: 16094385
• Homeotic Proboscipedia Function Modulates Hedgehog-mediated Organizer Activity to Pattern Adult Drosophila Mouthparts
  Developmental Biology. Feb, 2005  |   Pubmed ID: 15680366
• Prototype Alzheimer's Disease Vaccine Using the Immunodominant B Cell Epitope from Beta-amyloid and Promiscuous T Cell Epitope Pan HLA DR-binding Peptide
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005  |   Pubmed ID: 15661919
• Patterned Cell Culture Inside Microfluidic Devices
  Lab on a Chip. Jan, 2005  |   Pubmed ID: 15616747
• Mimotopes of Conformational Epitopes in Fibrillar Beta-amyloid
  Journal of Neuroimmunology. Nov, 2004  |   Pubmed ID: 15465592
• Abeta Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates Via the Proteasome
  Neuron. Aug, 2004  |   Pubmed ID: 15294141
• Caspase-mediated Degeneration in Alzheimer's Disease
  The American Journal of Pathology. Aug, 2004  |   Pubmed ID: 15277211
• Microfluidic Multicompartment Device for Neuroscience Research
  Langmuir : the ACS Journal of Surfaces and Colloids. Mar, 2003  |   Pubmed ID: 20725530
• Generation and Characterization of the Humoral Immune Response to DNA Immunization with a Chimeric Beta-amyloid-interleukin-4 Minigene
  European Journal of Immunology. Dec, 2003  |   Pubmed ID: 14635031
• Immunization with a Vaccine That Combines the Expression of MUC1 and B7 Co-stimulatory Molecules Prolongs the Survival of Mice and Delays the Appearance of Mouse Mammary Tumors
  Clinical & Experimental Metastasis. 2003  |   Pubmed ID: 14598882
• Fas and Fas Ligand Are Associated with Neuritic Degeneration in the AD Brain and Participate in Beta-amyloid-induced Neuronal Death
  Neurobiology of Disease. Apr, 2003  |   Pubmed ID: 12742739
• Adjuvant-dependent Modulation of Th1 and Th2 Responses to Immunization with Beta-amyloid
  International Immunology. Apr, 2003  |   Pubmed ID: 12663680
• The Induction of the TNFalpha Death Domain Signaling Pathway in Alzheimer's Disease Brain
  Neurochemical Research. Feb, 2003  |   Pubmed ID: 12608703
• Importance of IgG2c Isotype in the Immune Response to Beta-amyloid in Amyloid Precursor Protein/transgenic Mice
  Neuroscience Letters. Feb, 2003  |   Pubmed ID: 12565127
• Evidence for a Direct Functional Antagonism of the Selector Genes Proboscipedia and Eyeless in Drosophila Head Development
  Development (Cambridge, England). Feb, 2003  |   Pubmed ID: 12490563
• Beta-amyloid Deposition and Neurofibrillary Tangle Association with Caspase Activation in Down Syndrome
  Neuroscience Letters. Sep, 2002  |   Pubmed ID: 12213643
• Evidence for a Mediator of RNA Polymerase II Transcriptional Regulation Conserved from Yeast to Man
  Cell. Jul, 2002  |   Pubmed ID: 12150923
• The Drosophila Gene Taranis Encodes a Novel Trithorax Group Member Potentially Linked to the Cell Cycle Regulatory Apparatus
  Genetics. Feb, 2002  |   Pubmed ID: 11861561
• A P-insertion Screen Identifying Novel X-linked Essential Genes in Drosophila
  Mechanisms of Development. Jan, 2002  |   Pubmed ID: 11744370