David Lovinger Section on Synaptic Pharmacology/Laboratory for Integrative Neuroscience National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism Biography Publications Institution JoVE Articles David Lovinger has not added a biography. If you are David Lovinger and would like to personalize this page please email our Author Liaison for assistance. Publications Endocannabinoids in Striatal Plasticity Parkinsonism & Related Disorders. Jan, 2012 | Pubmed ID: 22166411 Serotonergic Action on Dorsal Striatal Function Parkinsonism & Related Disorders. Jan, 2012 | Pubmed ID: 22166410 Characterization of Two Mutations, M287L and Q266I, in the α1 Glycine Receptor Subunit That Modify Sensitivity to Alcohols The Journal of Pharmacology and Experimental Therapeutics. Feb, 2012 | Pubmed ID: 22037201 An Anticholinergic Reverses Motor Control and Corticostriatal LTD Deficits in Dyt1 ΔGAG Knock-in Mice Behavioural Brain Research. Jan, 2012 | Pubmed ID: 21995941 Subsets of Spiny Striosomal Striatal Neurons Revealed in the Gad1-GFP BAC Transgenic Mouse Basal Ganglia. Nov, 2011 | Pubmed ID: 22140656 Organophosphates Dysregulate Dopamine Signaling, Glutamatergic Neurotransmission, and Induce Neuronal Injury Markers in Striatum Journal of Neurochemistry. Oct, 2011 | Pubmed ID: 21848865 Synaptic and Morphological Neuroadaptations in the Putamen Associated with Long-term, Relapsing Alcohol Drinking in Primates Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Nov, 2011 | Pubmed ID: 21796110 Synaptic Effects Induced by Alcohol Current Topics in Behavioral Neurosciences. Jul, 2011 | Pubmed ID: 21786203 Cocaine Supersensitivity and Enhanced Motivation for Reward in Mice Lacking Dopamine D2 Autoreceptors Nature Neuroscience. Aug, 2011 | Pubmed ID: 21743470 Striatal Involvement in Human Alcoholism and Alcohol Consumption, and Withdrawal in Animal Models Alcoholism, Clinical and Experimental Research. Oct, 2011 | Pubmed ID: 21615425 Serotonin Induces Long-term Depression at Corticostriatal Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2011 | Pubmed ID: 21593324 Fluorophore Assisted Light Inactivation (FALI) of Recombinant 5-HT₃A Receptor Constitutive Internalization and Function Molecular and Cellular Neurosciences. Jun, 2011 | Pubmed ID: 21338684 N-Docosahexaenoylethanolamide Promotes Development of Hippocampal Neurons The Biochemical Journal. Apr, 2011 | Pubmed ID: 21281269 Endocannabinoids Rein in Pain Outside the Brain Nature Neuroscience. Oct, 2010 | Pubmed ID: 20877276 International Review of Neurobiology. Functional Plasticity and Genetic Variation: Insights into the Neurobiology of Alcoholism. Preface International Review of Neurobiology. 2010 | Pubmed ID: 20813237 Loss of GluN2B-containing NMDA Receptors in CA1 Hippocampus and Cortex Impairs Long-term Depression, Reduces Dendritic Spine Density, and Disrupts Learning The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20357110 Neurotransmitter Roles in Synaptic Modulation, Plasticity and Learning in the Dorsal Striatum Neuropharmacology. Jun, 2010 | Pubmed ID: 20096294 Developmental Alteration of Endocannabinoid Retrograde Signaling in the Hippocampus Journal of Neurophysiology. Feb, 2010 | Pubmed ID: 20007500 Hydrophobic Photolabeling Studies Identify the Lipid-protein Interface of the 5-HT3A Receptor Biochemistry. Oct, 2009 | Pubmed ID: 19715355 Docosahexaenoic Acid Promotes Hippocampal Neuronal Development and Synaptic Function Journal of Neurochemistry. Oct, 2009 | Pubmed ID: 19682204 Ethanol Increases Desensitization of Recombinant GluR-D AMPA Receptor and TARP Combinations Alcohol (Fayetteville, N.Y.). Jun, 2009 | Pubmed ID: 19560629 Acute Alcohol Action and Desensitization of Ligand-gated Ion Channels Pharmacological Reviews. Mar, 2009 | Pubmed ID: 19270242 Dynamic Reorganization of Striatal Circuits During the Acquisition and Consolidation of a Skill Nature Neuroscience. Mar, 2009 | Pubmed ID: 19198605 Frequency-dependent Inversion of Net Striatal Output by Endocannabinoid-dependent Plasticity at Different Synaptic Inputs The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2009 | Pubmed ID: 19193884 Endocannabinoid-dependent Plasticity at GABAergic and Glutamatergic Synapses in the Striatum is Regulated by Synaptic Activity The European Journal of Neuroscience. Jan, 2009 | Pubmed ID: 19120438 The Endogenous Brain Constituent N-arachidonoyl L-serine is an Activator of Large Conductance Ca2+-activated K+ Channels The Journal of Pharmacology and Experimental Therapeutics. Jan, 2009 | Pubmed ID: 18923087 Endocannabinoid- and MGluR5-dependent Short-term Synaptic Depression in an Isolated Neuron/bouton Preparation from the Hippocampal CA1 Region Journal of Neurophysiology. Aug, 2008 | Pubmed ID: 18497350 The L293 Residue in Transmembrane Domain 2 of the 5-HT3A Receptor is a Molecular Determinant of Allosteric Modulation by 5-hydroxyindole Neuropharmacology. Jun, 2008 | Pubmed ID: 18436267 Electrophysiological Properties and Gap Junction Coupling of Striatal Astrocytes Neurochemistry International. Jun, 2008 | Pubmed ID: 18396351 Presynaptic Modulation by Endocannabinoids Handbook of Experimental Pharmacology. 2008 | Pubmed ID: 18064422 Neurotensin Reduces Glutamatergic Transmission in the Dorsolateral Striatum Via Retrograde Endocannabinoid Signaling Neuropharmacology. Jan, 2008 | Pubmed ID: 17675102 Retrograde Endocannabinoid Signaling at Striatal Synapses Requires a Regulated Postsynaptic Release Step Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077376 Medication Discrepancies in Resident Sign-outs and Their Potential to Harm Journal of General Internal Medicine. Dec, 2007 | Pubmed ID: 17963009 Endocannabinoid Liberation from Neurons in Transsynaptic Signaling Journal of Molecular Neuroscience : MN. Sep, 2007 | Pubmed ID: 17901551 Combined Activation of L-type Ca2+ Channels and Synaptic Transmission is Sufficient to Induce Striatal Long-term Depression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2007 | Pubmed ID: 17581965 Ethanol Reverses the Direction of Long-term Synaptic Plasticity in the Dorsomedial Striatum The European Journal of Neuroscience. Jun, 2007 | Pubmed ID: 17552991 Tonic for What Ails Us? High-affinity GABAA Receptors and Alcohol Alcohol (Fayetteville, N.Y.). May, 2007 | Pubmed ID: 17521844 Ethanol Induces Long-term Facilitation of NR2B-NMDA Receptor Activity in the Dorsal Striatum: Implications for Alcohol Drinking Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2007 | Pubmed ID: 17392475 Persistent Synaptic Activity Produces Long-lasting Enhancement of Endocannabinoid Modulation and Alters Long-term Synaptic Plasticity Journal of Neurophysiology. Jun, 2007 | Pubmed ID: 17392410 Anandamide Regulates Postnatal Development of Long-term Synaptic Plasticity in the Rat Dorsolateral Striatum The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007 | Pubmed ID: 17329438 Mixing Proteomics and Alcohol Alcohol (Fayetteville, N.Y.). Aug, 2006 | Pubmed ID: 17157715 The Role of Protein Synthesis in Striatal Long-term Depression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2006 | Pubmed ID: 17108154 Disrupted Motor Learning and Long-term Synaptic Plasticity in Mice Lacking NMDAR1 in the Striatum Proceedings of the National Academy of Sciences of the United States of America. Oct, 2006 | Pubmed ID: 17015831 Ethanol Inhibits Brain-derived Neurotrophic Factor Stimulation of Extracellular Signal-regulated/mitogen-activated Protein Kinase in Cerebellar Granule Cells Alcohol (Fayetteville, N.Y.). May, 2006 | Pubmed ID: 16938627 Ethanol Effects on Electrophysiological Properties of Astrocytes in Striatal Brain Slices Neuropharmacology. Dec, 2006 | Pubmed ID: 16938316 Frequency-specific and D2 Receptor-mediated Inhibition of Glutamate Release by Retrograde Endocannabinoid Signaling Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16698932 Dopaminergic Control of Corticostriatal Long-term Synaptic Depression in Medium Spiny Neurons is Mediated by Cholinergic Interneurons Neuron. May, 2006 | Pubmed ID: 16675398 Temperature: an Important Experimental Variable in Studying PKC Modulation of Ligand-gated Ion Channels Brain Research. May, 2006 | Pubmed ID: 16626662 Ethanol Potentiates GABAergic Synaptic Transmission in a Postsynaptic Neuron/synaptic Bouton Preparation from Basolateral Amygdala Journal of Neurophysiology. Jul, 2006 | Pubmed ID: 16624993 Mutations of L293 in Transmembrane Two of the Mouse 5-hydroxytryptamine3A Receptor Alter Gating and Alcohol Modulatory Actions British Journal of Pharmacology. May, 2006 | Pubmed ID: 16520747 Effects of Ethanol on Adenosine 5'-triphosphate-gated Purinergic and 5-hydroxytryptamine Receptors Alcoholism, Clinical and Experimental Research. Feb, 2006 | Pubmed ID: 16441284 Actions of Acute and Chronic Ethanol on Presynaptic Terminals Alcoholism, Clinical and Experimental Research. Feb, 2006 | Pubmed ID: 16441271 Laboratory Models of Alcoholism: Treatment Target Identification and Insight into Mechanisms Nature Neuroscience. Nov, 2005 | Pubmed ID: 16251990 Activation of NR2A-containing NMDA Receptors is Not Obligatory for NMDA Receptor-dependent Long-term Potentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16162920 Role of Aspartate 298 in Mouse 5-HT3A Receptor Gating and Modulation by Extracellular Ca2+ The Journal of Physiology. Oct, 2005 | Pubmed ID: 16096341 Retrograde Endocannabinoid Signaling in a Postsynaptic Neuron/synaptic Bouton Preparation from Basolateral Amygdala The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15987949 Molecular and Cellular Neurosciences. May, 2005 | Pubmed ID: 15866054 Maturation of Cultured Hippocampal Slices Results in Increased Excitability in Granule Cells International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Feb, 2005 | Pubmed ID: 15730888 Induction of Striatal Long-term Synaptic Depression by Moderate Frequency Activation of Cortical Afferents in Rat The Journal of Physiology. Jan, 2005 | Pubmed ID: 15498813 Cortical Neurons Lacking KCC2 Expression Show Impaired Regulation of Intracellular Chloride Journal of Neurophysiology. Mar, 2005 | Pubmed ID: 15469961 Serotonin-3 Receptors in the Actions of Alcohol, Alcohol Reinforcement, and Alcoholism Alcoholism, Clinical and Experimental Research. Feb, 2004 | Pubmed ID: 15112933 Disruption of Endocannabinoid Release and Striatal Long-term Depression by Postsynaptic Blockade of Endocannabinoid Membrane Transport The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2004 | Pubmed ID: 14973237 Plastic Control of Striatal Glutamatergic Transmission by Ensemble Actions of Several Neurotransmitters and Targets for Drugs of Abuse Annals of the New York Academy of Sciences. Nov, 2003 | Pubmed ID: 14684449 A Predominant Role for Inhibition of the Adenylate Cyclase/protein Kinase A Pathway in ERK Activation by Cannabinoid Receptor 1 in N1E-115 Neuroblastoma Cells The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14517212 Emerging Roles for Endocannabinoids in Long-term Synaptic Plasticity British Journal of Pharmacology. Nov, 2003 | Pubmed ID: 14504143 G Protein-coupled Endothelial Receptor for Atypical Cannabinoid Ligands Modulates a Ca2+-dependent K+ Current The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12952947 Ethanol Inhibits Alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Function in Central Nervous System Neurons by Stabilizing Desensitization The Journal of Pharmacology and Experimental Therapeutics. Aug, 2003 | Pubmed ID: 12734392 A Mutation in Transmembrane Domain II of the 5-hydroxytryptamine(3A) Receptor Stabilizes Channel Opening and Alters Alcohol Modulatory Actions The Journal of Pharmacology and Experimental Therapeutics. Aug, 2003 | Pubmed ID: 12730353 Phorbol Ester Uncouples Adenosine Inhibition of Presynaptic Ca2+ Transients at Hippocampal Synapses Hippocampus. 2003 | Pubmed ID: 12722976 It Could Be Habit Forming: Drugs of Abuse and Striatal Synaptic Plasticity Trends in Neurosciences. Apr, 2003 | Pubmed ID: 12689769 NMDA Receptors Lose Their Inhibitions Nature Neuroscience. Jul, 2002 | Pubmed ID: 12085089 Dicinnamoylquinides in Roasted Coffee Inhibit the Human Adenosine Transporter European Journal of Pharmacology. May, 2002 | Pubmed ID: 12065074 Hyperexcitability and Epilepsy Associated with Disruption of the Mouse Neuronal-specific K-Cl Cotransporter Gene Hippocampus. 2002 | Pubmed ID: 12000122 Nicotinic Acetylcholine Receptors Interact with Dopamine in Induction of Striatal Long-term Depression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2002 | Pubmed ID: 11923419 Vibrodissociation нейронов из кусочков мозга грызунов по изучению синаптической передачи изображения и пресинаптические терминалы Sang Beom Jun1,2, Verginia Cuzon Carlson1, Stephen Ikeda3, David Lovinger1 1Section on Synaptic Pharmacology/Laboratory for Integrative Neuroscience, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, 2Department of Electronics Engineering, Ewha Womans University, 3Section on Transmitter Signaling/Laboratory of Molecular Physiology, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism JoVE 2752 Neuroscience
Vibrodissociation нейронов из кусочков мозга грызунов по изучению синаптической передачи изображения и пресинаптические терминалы Sang Beom Jun1,2, Verginia Cuzon Carlson1, Stephen Ikeda3, David Lovinger1 1Section on Synaptic Pharmacology/Laboratory for Integrative Neuroscience, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism, 2Department of Electronics Engineering, Ewha Womans University, 3Section on Transmitter Signaling/Laboratory of Molecular Physiology, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism JoVE 2752 Neuroscience