Deon Bezuidenhout Cardiovascular Research Unit University of Cape Town Biography Publications Institution JoVE Articles Deon Bezuidenhout has not added a biography. If you are Deon Bezuidenhout and would like to personalize this page please email our Author Liaison for assistance. Publications The Technological Basis of a Balloon-Expandable TAVR System: Non-occlusive Deployment, Anchorage in the Absence of Calcification and Polymer Leaflets Frontiers in Cardiovascular Medicine. 2022 | Pubmed ID: 35310972 Residual Bioprosthetic Valve Immunogenicity: Forgotten, Not Lost Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 35059444 Long-Term Stability and Biocompatibility of Pericardial Bioprosthetic Heart Valves Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34589529 TAVR for Patients With Rheumatic Heart Disease: Opening the Door for the Many? Journal of the American College of Cardiology. 04, 2021 | Pubmed ID: 33832597 Tendon-like Tether Formation for Tongue-base Advancement in an Ovine Model Using a Novel Implant Device Intended for the Surgical Management of Obstructive Sleep Apnoea Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 07, 2021 | Pubmed ID: 33283474 Analysis of the Regenerative Capacity of Human Serum Exosomes After a Simple Multistep Separation from Lipoproteins Journal of Tissue Engineering and Regenerative Medicine. 01, 2021 | Pubmed ID: 33175463 Progressive Reinvention or Destination Lost? Half a Century of Cardiovascular Tissue Engineering Frontiers in Cardiovascular Medicine. 2020 | Pubmed ID: 33033720 Decellularization and Engineered Crosslinking: a Promising Dual Approach Towards Bioprosthetic Heart Valve Longevity European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. 12, 2020 | Pubmed ID: 32893300 Tissue Ingrowth Markedly Reduces Mechanical Anisotropy and Stiffness in Fibre Direction of Highly Aligned Electrospun Polyurethane Scaffolds Cardiovascular Engineering and Technology. 08, 2020 | Pubmed ID: 32613599 Customized Stent-grafts for Endovascular Aneurysm Repair with Challenging Necks: A Numerical Proof of Concept International Journal for Numerical Methods in Biomedical Engineering. 04, 2020 | Pubmed ID: 32022404 A Preliminary Computational Investigation Into the Flow of PEG in Rat Myocardial Tissue for Regenerative Therapy Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 31448288 Preclinical Evaluation of a Transcatheter Aortic Valve Replacement System for Patients with Rheumatic Heart Disease EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. Dec, 2019 | Pubmed ID: 31403458 Performance Analysis of the Transcatheter Aortic Valve Implantation on Blood Flow Hemodynamics: An Optical Imaging-based in Vitro Study Artificial Organs. Oct, 2019 | Pubmed ID: 31140632 A Truly Non-occlusive Stent-graft Moulding Balloon for Thoracic Endovascular Aortic Repair Interactive Cardiovascular and Thoracic Surgery. 09, 2019 | Pubmed ID: 30977794 Suitability of Developed Composite Materials for Meniscal Replacement: Mechanical, Friction and Wear Evaluation Journal of the Mechanical Behavior of Biomedical Materials. 01, 2019 | Pubmed ID: 30296703 Transcatheter Valve with a Hollow Balloon for Aortic Valve Insufficiency Multimedia Manual of Cardiothoracic Surgery : MMCTS. Feb, 2018 | Pubmed ID: 29629555 Synthetic Extracellular Matrix Mimic Hydrogel Improves Efficacy of Mesenchymal Stromal Cell Therapy for Ischemic Cardiomyopathy Acta Biomaterialia. 04, 2018 | Pubmed ID: 29341932 Transmural Capillary Ingrowth is Essential for Confluent Vascular Graft Healing Acta Biomaterialia. Jan, 2018 | Pubmed ID: 29111372 Rapidly Recoverable Thixotropic Hydrogels from the Racemate of Chiral OFm Monosubstituted Cyclo(Glu-Glu) Derivatives Langmuir : the ACS Journal of Surfaces and Colloids. 12, 2017 | Pubmed ID: 29110482 High Heparin Content Surface-modified Polyurethane Discs Promote Rapid and Stable Angiogenesis in Full Thickness Skin Defects Through VEGF Immobilization Journal of Biomedical Materials Research. Part A. Sep, 2017 | Pubmed ID: 28509406 Improved Vascularization of Porous Scaffolds Through Growth Factor Delivery from Heparinized Polyethylene Glycol Hydrogels Acta Biomaterialia. 02, 2017 | Pubmed ID: 27865963 Dual Electrospinning with Sacrificial Fibers for Engineered Porosity and Enhancement of Tissue Ingrowth Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 08, 2017 | Pubmed ID: 27125901 Cast Tube Assay: A 3-D in Vitro Assay for Visualization and Quantification of Horizontal Chemotaxis and Cellular Invasion BioTechniques. 2016 | Pubmed ID: 27528071 The Anisotropic Mechanical Behaviour of Electro-spun Biodegradable Polymer Scaffolds: Experimental Characterisation and Constitutive Formulation Journal of the Mechanical Behavior of Biomedical Materials. Jan, 2016 | Pubmed ID: 26301317 Coacervate Delivery of Growth Factors Combined with a Degradable Hydrogel Preserves Heart Function After Myocardial Infarction ACS Biomaterials Science & Engineering. Sep, 2015 | Pubmed ID: 33445252 The Performance of Cross-linked Acellular Arterial Scaffolds As Vascular Grafts; Pre-clinical Testing in Direct and Isolation Loop Circulatory Models Biomaterials. Aug, 2014 | Pubmed ID: 24816365 Nitric Oxide Release from Polydimethylsiloxane-based Polyurethanes Journal of Applied Biomaterials & Functional Materials. Dec, 2014 | Pubmed ID: 24744231 A Slow-release Fibrin Matrix Increases Adeno-associated Virus Transduction of Wound Repair Cells in Vivo Journal of Biomaterials Applications. May, 2014 | Pubmed ID: 24163331 Cell Specific Ingrowth Hydrogels Biomaterials. Sep, 2013 | Pubmed ID: 23777918 Differentiating Transmural from Transanastomotic Prosthetic Graft Endothelialization Through an Isolation Loop-graft Model Journal of Vascular Surgery. Oct, 2013 | Pubmed ID: 23541549 Protective Constriction of Coronary Vein Grafts with Knitted Nitinol European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2013 | Pubmed ID: 23295444 Covalent Incorporation and Controlled Release of Active Dexamethasone from Injectable Polyethylene Glycol Hydrogels Journal of Biomedical Materials Research. Part A. May, 2013 | Pubmed ID: 23065782 The Beneficial Effects of Deferred Delivery on the Efficiency of Hydrogel Therapy Post Myocardial Infarction Biomaterials. Mar, 2012 | Pubmed ID: 22153866 Sustaining Neovascularization of a Scaffold Through Staged Release of Vascular Endothelial Growth Factor-A and Platelet-derived Growth Factor-BB Tissue Engineering. Part A. Jan, 2012 | Pubmed ID: 21895488 Degradation-induced Changes of Mechanical Properties of an Electro-spun Polyester-urethane Scaffold for Soft Tissue Regeneration Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2011 | Pubmed ID: 21948379 Knitted Nitinol Represents a New Generation of Constrictive External Vein Graft Meshes Journal of Vascular Surgery. Nov, 2011 | Pubmed ID: 21802240 Induced Chronic Hypoxia Negates the Pro-angiogenic Effect of Surface Immobilized Heparin in a Polyurethane Porous Scaffold Journal of Biomedical Materials Research. Part A. Sep, 2011 | Pubmed ID: 21732524 Tailored Sizes of Constrictive External Vein Meshes for Coronary Artery Bypass Surgery Biomaterials. Dec, 2010 | Pubmed ID: 20864157 Covalent Surface Heparinization Potentiates Porous Polyurethane Scaffold Vascularization Journal of Biomaterials Applications. Jan, 2010 | Pubmed ID: 19033329 The Effects of Cross-link Density and Chemistry on the Calcification Potential of Diamine-extended Glutaraldehyde-fixed Bioprosthetic Heart-valve Materials Biotechnology and Applied Biochemistry. Nov, 2009 | Pubmed ID: 19882764 A Synthetic Non-degradable Polyethylene Glycol Hydrogel Retards Adverse Post-infarct Left Ventricular Remodeling Journal of Cardiac Failure. Sep, 2009 | Pubmed ID: 19700140 Rapid Three-dimensional Quantification of VEGF-induced Scaffold Neovascularisation by Microcomputed Tomography Biomaterials. Oct, 2009 | Pubmed ID: 19664820 Utilization of Shape Memory in External Vein-graft Meshes Allows Extreme Diameter Constriction for Suppressing Intimal Hyperplasia: a Non-human Primate Study Journal of Vascular Surgery. Jun, 2009 | Pubmed ID: 19497517 Constrictive External Nitinol Meshes Inhibit Vein Graft Intimal Hyperplasia in Nonhuman Primates The Journal of Thoracic and Cardiovascular Surgery. Sep, 2008 | Pubmed ID: 18805277 The Dosage Dependence of VEGF Stimulation on Scaffold Neovascularisation Biomaterials. Sep, 2008 | Pubmed ID: 18541296 A Computational Study of Knitted Nitinol Meshes for Their Prospective Use As External Vein Reinforcement Journal of Biomechanics. 2008 | Pubmed ID: 18328487 Prosthetic Heart Valves: Catering for the Few Biomaterials. Feb, 2008 | Pubmed ID: 17950840 Prosthetic Vascular Grafts: Wrong Models, Wrong Questions and No Healing Biomaterials. Dec, 2007 | Pubmed ID: 17688939 Bioprosthetic Tissue Preservation by Filling with a Poly(acrylamide) Hydrogel Biomaterials. Mar, 2006 | Pubmed ID: 16263164 Diamine-extended Glutaraldehyde- and Carbodiimide Crosslinks Act Synergistically in Mitigating Bioprosthetic Aortic Wall Calcification The Journal of Heart Valve Disease. Jul, 2005 | Pubmed ID: 16116882 Carbodiimide Treatment Dramatically Potentiates the Anticalcific Effect of Alpha-amino Oleic Acid on Glutaraldehyde-fixed Aortic Wall Tissue The Annals of Thoracic Surgery. Mar, 2005 | Pubmed ID: 15734403 Bioprosthetic Heart Valves: the Need for a Quantum Leap Biotechnology and Applied Biochemistry. Aug, 2004 | Pubmed ID: 15270708 Effect of Well Defined Dodecahedral Porosity on Inflammation and Angiogenesis ASAIO Journal (American Society for Artificial Internal Organs : 1992). Sep-Oct, 2002 | Pubmed ID: 12296563 Optimization of Diamine Bridges in Glutaraldehyde Treated Bioprosthetic Aortic Wall Tissue Biomaterials. May, 2002 | Pubmed ID: 11962649 3D 프린팅과 전기방사를 결합하여 생체모방 심장 판막 전단지 제조 Benedikt Freystetter1, Maximilian Grab1,2, Linda Grefen1, Lara Bischof1, Lorenz Isert3, Petra Mela2, Deon Bezuidenhout4, Christian Hagl1,5, Nikolaus Thierfelder1 1Department of Cardiac Surgery, Ludwig Maximilians University Munich, 2Chair of Medical Materials and Implants, Technical University Munich, 3Faculty for Chemistry and Pharmacy, Ludwig Maximilians University Munich, 4Cardiovascular Research Unit, University of Cape Town, 5DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance JoVE 63604 Medicine
3D 프린팅과 전기방사를 결합하여 생체모방 심장 판막 전단지 제조 Benedikt Freystetter1, Maximilian Grab1,2, Linda Grefen1, Lara Bischof1, Lorenz Isert3, Petra Mela2, Deon Bezuidenhout4, Christian Hagl1,5, Nikolaus Thierfelder1 1Department of Cardiac Surgery, Ludwig Maximilians University Munich, 2Chair of Medical Materials and Implants, Technical University Munich, 3Faculty for Chemistry and Pharmacy, Ludwig Maximilians University Munich, 4Cardiovascular Research Unit, University of Cape Town, 5DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance JoVE 63604 Medicine
