Dunja Bruder Immune Regulation Group Helmholtz Centre for Infection Research Biography Publications Institution JoVE Articles Dunja Bruder has not added a biography. If you are Dunja Bruder and would like to personalize this page please email our Author Liaison for assistance. Publications Eosinophilic Pulmonary Vasculitis As a Manifestation of the Hyperinflammatory Phase of COVID-19 The Journal of Allergy and Clinical Immunology. 01, 2021 | Pubmed ID: 33139059 Resolved Influenza A Virus Infection Has Extended Effects on Lung Homeostasis and Attenuates Allergic Airway Inflammation in a Mouse Model Microorganisms. Nov, 2020 | Pubmed ID: 33260910 NMP4: a Nuclear Driver of Innate Inflammatory Responses During Influenza A Virus Infection Cellular & Molecular Immunology. Dec, 2020 | Pubmed ID: 32747686 Topological Data Analysis to Model the Shape of Immune Responses During Co-infections Communications in Nonlinear Science & Numerical Simulation. Jun, 2020 | Pubmed ID: 32288422 ADAP Promotes Degranulation and Migration of NK Cells Primed During Infection in Mice Frontiers in Immunology. 2019 | Pubmed ID: 32038647 Mucosal CD8+ T Cell Responses Induced by an MCMV Based Vaccine Vector Confer Protection Against Influenza Challenge PLoS Pathogens. 09, 2019 | Pubmed ID: 31525249 Neutralization of Pro-inflammatory Cytokines During Secondary Infection Post Influenza A Virus Infection Frontiers in Immunology. 2019 | Pubmed ID: 31474978 The STING Activator C-di-AMP Exerts Superior Adjuvant Properties Than the Formulation Poly(I:C)/CpG After Subcutaneous Vaccination with Soluble Protein Antigen or DEC-205-mediated Antigen Targeting to Dendritic Cells Vaccine. 08, 2019 | Pubmed ID: 31320219 Essential Role of IκB for in Vivo CD4 T-cell Activation, Proliferation, and Th1-cell Differentiation During Listeria Monocytogenes Infection in Mice European Journal of Immunology. 09, 2019 | Pubmed ID: 31049948 Gamma Secretase Dependent Release of the CD44 Cytoplasmic Tail Upregulates IFI16 in Cd44-/- Tumor Cells, MEFs and Macrophages PloS One. 2018 | Pubmed ID: 30540779 Activates Human Mucosal-Associated Invariant T Cells Frontiers in Microbiology. 2018 | Pubmed ID: 30410474 Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice Frontiers in Immunology. 2018 | Pubmed ID: 30386330 Hemodialysis-related Changes in Phenotypical Features of Monocytes Scientific Reports. 09, 2018 | Pubmed ID: 30228352 Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice International Journal of Molecular Sciences. Sep, 2018 | Pubmed ID: 30200513 Proteomic Definition of Human Mucosal-associated Invariant T cells Determines Their Unique Molecular Effector Phenotype European Journal of Immunology. 08, 2018 | Pubmed ID: 29749611 Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation Toll-Like Receptor 7 Frontiers in Immunology. 2018 | Pubmed ID: 29497422 Chronic Lung Inflammation Primes Humoral Immunity and Augments Antipneumococcal Resistance Scientific Reports. 07, 2017 | Pubmed ID: 28694492 IL-33: a Jack of All Trades in the Orchestration of Respiratory Antibacterial Immunity Cellular & Molecular Immunology. Jul, 2017 | Pubmed ID: 28690328 C-REL and IκB Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors Journal of Immunology (Baltimore, Md. : 1950). 08, 2017 | Pubmed ID: 28652399 Targeted Antigen Delivery to Dendritic Cells Elicits Robust Antiviral T Cell-mediated Immunity in the Liver Scientific Reports. Mar, 2017 | Pubmed ID: 28266658 Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course Lung. 02, 2017 | Pubmed ID: 27864635 Mechanism of Granuloma Formation in Sarcoidosis Current Opinion in Hematology. 01, 2017 | Pubmed ID: 27755127 ADAP Plays a Pivotal Role in CD4+ T Cell Activation but is Only Marginally Involved in CD8+ T Cell Activation, Differentiation, and Immunity to Pathogens Journal of Leukocyte Biology. 02, 2017 | Pubmed ID: 27605210 Hierarchical Effects of Pro-inflammatory Cytokines on the Post-influenza Susceptibility to Pneumococcal Coinfection Scientific Reports. 11, 2016 | Pubmed ID: 27872472 A Cell Culture-derived Whole Virus Influenza A Vaccine Based on Magnetic Sulfated Cellulose Particles Confers Protection in Mice Against Lethal Influenza A Virus Infection Vaccine. 12, 2016 | Pubmed ID: 27816372 Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus Pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation Infection and Immunity. Dec, 2016 | Pubmed ID: 27647871 Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies Against Influenza-Pneumococcus Coinfection Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27379214 Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals MBio. May, 2016 | Pubmed ID: 27143386 ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus Fumigatus Lung Infection in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787852 Modeling Influenza Virus Infection: A Roadmap for Influenza Research Viruses. Oct, 2015 | Pubmed ID: 26473911 Erratum To: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26459043 Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26319657 First Genomic Analysis of Dendritic Cells from Lung and Draining Lymph Nodes in Murine Asthma International Journal of Genomics. 2015 | Pubmed ID: 25811019 Ly6C(high) Monocytes Control Cerebral Toxoplasmosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710908 Evidence for a Causal Link Between Adaptor Protein PDZK1 Downregulation and Na⁺/H⁺ Exchanger NHE3 Dysfunction in Human and Murine Colitis Pflugers Archiv : European Journal of Physiology. Aug, 2015 | Pubmed ID: 25271043 Attenuation of Immune-mediated Influenza Pneumonia by Targeting the Inducible Co-stimulator (ICOS) Molecule on T Cells PloS One. 2014 | Pubmed ID: 25029240 Interferon Regulatory Factor-1 Protects from Fatal Neurotropic Infection with Vesicular Stomatitis Virus by Specific Inhibition of Viral Replication in Neurons PLoS Pathogens. Mar, 2014 | Pubmed ID: 24675692 ChIP-on-chip Analysis Identifies IL-22 As Direct Target Gene of Ectopically Expressed FOXP3 Transcription Factor in Human T Cells BMC Genomics. Dec, 2012 | Pubmed ID: 23244505 TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease Following Influenza A Virus Infection Journal of Innate Immunity. Nov, 2012 | Pubmed ID: 23154432 IL-4 Attenuates Pulmonary Epithelial Cell-mediated Suppression of T Cell Priming PloS One. 2012 | Pubmed ID: 23029313 CD8+ T Cells Responding to Alveolar Self-Antigen Lack CD25 Expression and Fail to Precipitate Autoimmunity American Journal of Respiratory Cell and Molecular Biology. Dec, 2012 | Pubmed ID: 22984087 Therapeutic Intervention in Cancer and Chronic Viral Infections: Antibody Mediated Manipulation of PD-1/PD-L1 Interaction Reviews on Recent Clinical Trials. Feb, 2012 | Pubmed ID: 22023178 Expression QTL Mapping in Regulatory and Helper T Cells from the BXD Family of Strains Reveals Novel Cell-specific Genes, Gene-gene Interactions and Candidate Genes for Auto-immune Disease BMC Genomics. 2011 | Pubmed ID: 22182475 Senescence Surveillance of Pre-malignant Hepatocytes Limits Liver Cancer Development Nature. Nov, 2011 | Pubmed ID: 22080947 Human Regulatory T Cells in Allogeneic Stem Cell Transplantation Blood. Sep, 2011 | Pubmed ID: 21778340 New Insights into the Molecular Pathology of Radiation-induced Pneumopathy Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011 | Pubmed ID: 21722981 CD4+CD25+Foxp3+ Regulatory T Cells Are Dispensable for Controlling CD8+ T Cell-mediated Lung Inflammation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21518973 Inhibition of Lymphocyte Trafficking Shields the Brain Against Deleterious Neuroinflammation After Stroke Brain : a Journal of Neurology. Mar, 2011 | Pubmed ID: 21354973 CX3CR1+ CD8alpha+ Dendritic Cells Are a Steady-state Population Related to Plasmacytoid Dendritic Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20679228 Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-beta in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19667093 Frequency and Gene Expression Profile of Regulatory T Cells in Renal Cell Carcinoma Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. 2009 | Pubmed ID: 19609102 Host Genetic Background Strongly Influences the Response to Influenza a Virus Infections PloS One. 2009 | Pubmed ID: 19293935 Increased Susceptibility for Superinfection with Streptococcus Pneumoniae During Influenza Virus Infection is Not Caused by TLR7-mediated Lymphopenia PloS One. 2009 | Pubmed ID: 19290047 Alveolar Type II Epithelial Cells Present Antigen to CD4(+) T Cells and Induce Foxp3(+) Regulatory T Cells American Journal of Respiratory and Critical Care Medicine. Mar, 2009 | Pubmed ID: 19096007 Probiotic Escherichia Coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity PloS One. 2007 | Pubmed ID: 18074031 Chronic Antigen Stimulation in Vivo Induces a Distinct Population of Antigen-specific Foxp3 CD25 Regulatory T Cells Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056346 Phenotypic Alterations in Type II Alveolar Epithelial Cells in CD4+ T Cell Mediated Lung Inflammation Respiratory Research. 2007 | Pubmed ID: 17610738 Intestinal Epithelial Antigen Induces CD4+ T Cells with Regulatory Phenotype in a Transgenic Autoimmune Mouse Model Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057222 Autoimmune-mediated Intestinal Inflammation-impact and Regulation of Antigen-specific CD8+ T Cells Gastroenterology. Aug, 2006 | Pubmed ID: 16890605 Cellular Immunity and Lung Injury in Respiratory Virus Infection Viral Immunology. 2006 | Pubmed ID: 16817757 G Protein-coupled Receptor 83 Overexpression in Naive CD4+CD25- T Cells Leads to the Induction of Foxp3+ Regulatory T Cells in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006 | Pubmed ID: 16785516 Lung Epithelial NF-kappaB and Stat1 Signaling in Response to CD8+ T Cell Antigen Recognition Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. May, 2006 | Pubmed ID: 16689660 Multiple Synergizing Factors Contribute to the Strength of the CD8+ T Cell Response Against Listeriolysin O International Immunology. Jan, 2006 | Pubmed ID: 16291651 On the Edge of Autoimmunity: T-cell Stimulation by Steady-state Dendritic Cells Prevents Autoimmune Diabetes Diabetes. Dec, 2005 | Pubmed ID: 16306354 Intestinal Immunity of Escherichia Coli NISSLE 1917: a Safe Carrier for Therapeutic Molecules FEMS Immunology and Medical Microbiology. Mar, 2005 | Pubmed ID: 15708311 Characterization of a B220+ Lymphoid Cell Subpopulation with Immune Modulatory Functions in Nasal-associated Lymphoid Tissues Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005 | Pubmed ID: 15661888 CD4 T Lymphocyte-mediated Lung Disease: Steady State Between Pathological and Tolerogenic Immune Reactions American Journal of Respiratory and Critical Care Medicine. Dec, 2004 | Pubmed ID: 15306530 Neuropilin-1: a Surface Marker of Regulatory T Cells European Journal of Immunology. Mar, 2004 | Pubmed ID: 14991591 Conjugação Química de um anticorpo purificado DEC-205-Directed com proteína de comprimento completo para direcionar células dendríticas de camundongos in vitro e in vivo Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research Isolamento de citometria de fluxo de células primárias Murino Tipo II epiteliais alveolares de Estudos funcionais e Molecular Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
Conjugação Química de um anticorpo purificado DEC-205-Directed com proteína de comprimento completo para direcionar células dendríticas de camundongos in vitro e in vivo Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research
Isolamento de citometria de fluxo de células primárias Murino Tipo II epiteliais alveolares de Estudos funcionais e Molecular Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
