E. Scott Graham

Publications

• The Interaction of Placental Micro-EVs with Immune Cells in Vivo and in Vitro
  American Journal of Reproductive Immunology (New York, N.Y. : 1989). Sep, 2023  |   Pubmed ID: 37641368
• Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins
  International Journal of Molecular Sciences. Mar, 2023  |   Pubmed ID: 37047054
• Comprehensive Assessment of Secreted Immuno-Modulatory Cytokines by Serum-Differentiated and Stem-like Glioblastoma Cells Reveals Distinct Differences Between Glioblastoma Phenotypes
  International Journal of Molecular Sciences. Nov, 2022  |   Pubmed ID: 36430641
• Critical Spatial-Temporal Dynamics and Prominent Shape Collapse of Calcium Waves Observed in Human HNT Astrocytes
  Frontiers in Physiology. 2022  |   Pubmed ID: 35784870
• Serum Biomarkers of Neuroinflammation and Blood-brain Barrier Leakage in Amyotrophic Lateral Sclerosis
  BMC Neurology. Jun, 2022  |   Pubmed ID: 35690735
• Can ECIS Biosensor Technology Be Used to Measure the Cellular Responses of Glioblastoma Stem Cells?
  Biosensors. Dec, 2021  |   Pubmed ID: 34940255
• Superior Galvanostatic Electrochemical Deposition of Platinum Nanograss Provides High Performance Planar Microelectrodes Forneural Recording
  Journal of Neural Engineering. Aug, 2021  |   Pubmed ID: 34371484
• Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time
  Biosensors. May, 2021  |   Pubmed ID: 34069959
• Geometric Micro-shapes Facilitate Trackless Connections Between Human Astrocytes
  Journal of Neural Engineering. Apr, 2021  |   Pubmed ID: 33601342
• Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells
  International Journal of Molecular Sciences. Nov, 2020  |   Pubmed ID: 33139674
• Cannabinoid Receptor 2 (CB) Signals Via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes
  ACS Pharmacology & Translational Science. Dec, 2019  |   Pubmed ID: 32259074
• Bradykinin Receptor-1 Activation Induces Inflammation and Increases the Permeability of Human Brain Microvascular Endothelial Cells
  Cell Biology International. Sep, 2019  |   Pubmed ID: 31498530
• Large 10  ×  10 Single Cell Grid Networks of Human HNT Astrocytes on Raised Parylene-C/SiO Substrates
  Journal of Neural Engineering. Oct, 2019  |   Pubmed ID: 31394515
• Evaluation of Parylene Derivatives for Use As Biomaterials for Human Astrocyte Cell Patterning
  PloS One. 2019  |   Pubmed ID: 31237927
• Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology
  Biosensors. Apr, 2019  |   Pubmed ID: 30991758
• In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology
  Biosensors. Oct, 2018  |   Pubmed ID: 30314393
• The Functional and Inflammatory Response of Brain Endothelial Cells to Toll-Like Receptor Agonists
  Scientific Reports. Jul, 2018  |   Pubmed ID: 29973684
• The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier
  Biosensors. Jul, 2018  |   Pubmed ID: 29973526
• The Inflammasome Pathway is Amplified and Perpetuated in an Autocrine Manner Through Connexin43 Hemichannel Mediated ATP Release
  Biochimica Et Biophysica Acta. General Subjects. Mar, 2018  |   Pubmed ID: 29158134
• Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products
  Biosensors. Sep, 2017  |   Pubmed ID: 28934106
• Is the Cannabinoid CB Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans?
  Advances in Pharmacology (San Diego, Calif.). 2017  |   Pubmed ID: 28826541
• ECIS Technology Reveals That Monocytes Isolated by CD14+ve Selection Mediate Greater Loss of BBB Integrity Than Untouched Monocytes, Which Occurs to a Greater Extent with IL-1β Activated Endothelium in Comparison to TNFα
  PloS One. 2017  |   Pubmed ID: 28732059
• Interferon-γ Blocks Signalling Through PDGFRβ in Human Brain Pericytes
  Journal of Neuroinflammation. Sep, 2016  |   Pubmed ID: 27654972
• Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier
  PloS One. 2016  |   Pubmed ID: 27309956
• Plasmin and Regulators of Plasmin Activity Control the Migratory Capacity and Adhesion of Human T Cells and Dendritic Cells by Regulating Cleavage of the Chemokine CCL21
  Immunology and Cell Biology. Nov, 2016  |   Pubmed ID: 27301418
• Cultured Pericytes from Human Brain Show Phenotypic and Functional Differences Associated with Differential CD90 Expression
  Scientific Reports. 05, 2016  |   Pubmed ID: 27215737
• TGF-beta1 Regulates Human Brain Pericyte Inflammatory Processes Involved in Neurovasculature Function
  Journal of Neuroinflammation. Feb, 2016  |   Pubmed ID: 26867675
• Regulation of Human Cerebro-microvascular Endothelial Baso-lateral Adhesion and Barrier Function by S1P Through Dual Involvement of S1P1 and S1P2 Receptors
  Scientific Reports. Jan, 2016  |   Pubmed ID: 26813587
• Pro-inflammatory TNFα and IL-1β Differentially Regulate the Inflammatory Phenotype of Brain Microvascular Endothelial Cells
  Journal of Neuroinflammation. Jul, 2015  |   Pubmed ID: 26152369
• Application of XCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time
  Biosensors. Apr, 2015  |   Pubmed ID: 25893878
• Development of Positive Control Tissue for in Situ Hybridisation Using Alvetex Scaffolds
  Journal of Neuroscience Methods. Dec, 2014  |   Pubmed ID: 25244955
• Enrichment of Differentiated HNT Neurons and Subsequent Analysis Using Flow-cytometry and XCELLigence Sensing
  Journal of Neuroscience Methods. Apr, 2014  |   Pubmed ID: 24530700
• Exposure to Inflammatory Cytokines IL-1β and TNFα Induces Compromise and Death of Astrocytes; Implications for Chronic Neuroinflammation
  PloS One. 2013  |   Pubmed ID: 24367648
• A Cell Derived Active Contour (CDAC) Method for Robust Tracking in Low Frame Rate, Low Contrast Phase Microscopy - an Example: the Human HNT Astrocyte
  PloS One. 2013  |   Pubmed ID: 24358233
• Adult Human Glia, Pericytes and Meningeal Fibroblasts Respond Similarly to IFNy but Not to TGFβ1 or M-CSF
  PloS One. 2013  |   Pubmed ID: 24339874
• M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells
  PloS One. 2013  |   Pubmed ID: 24023725
• Sensitive and Accurate Quantification of Human Leukocyte Migration Using High-content Discovery-1 Imaging System and ATPlite Assay
  Journal of Biomolecular Screening. Mar, 2012  |   Pubmed ID: 22140120
• Detailed Analysis of Inflammatory and Neuromodulatory Cytokine Secretion from Human NT2 Astrocytes Using Multiplex Bead Array
  Neurochemistry International. May, 2012  |   Pubmed ID: 21939706
• Real-time Profiling of NK Cell Killing of Human Astrocytes Using XCELLigence Technology
  Journal of Neuroscience Methods. Sep, 2011  |   Pubmed ID: 21781988
• Cannabinoid Receptor 1 Trafficking and the Role of the Intracellular Pool: Implications for Therapeutics
  Biochemical Pharmacology. Oct, 2010  |   Pubmed ID: 20599795
• Detailed Characterisation of CB2 Receptor Protein Expression in Peripheral Blood Immune Cells from Healthy Human Volunteers Using Flow Cytometry
  International Journal of Immunopathology and Pharmacology. 2010  |   Pubmed ID: 20377992
• Cannabinoid Receptors: A Brief History and What Not
  Frontiers in Bioscience (Landmark Edition). Jan, 2009  |   Pubmed ID: 19273110
• Specific Detection of CB1 Receptors; Cannabinoid CB1 Receptor Antibodies Are Not All Created Equal!
  Journal of Neuroscience Methods. Jun, 2008  |   Pubmed ID: 18406468
• Induction of Krox-24 by Endogenous Cannabinoid Type 1 Receptors in Neuro2A Cells is Mediated by the MEK-ERK MAPK Pathway and is Suppressed by the Phosphatidylinositol 3-kinase Pathway
  The Journal of Biological Chemistry. Sep, 2006  |   Pubmed ID: 16864584