Eileen McNeill BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital University of Oxford Biography Publications Institution JoVE Articles Eileen McNeill has not added a biography. If you are Eileen McNeill and would like to personalize this page please email our Author Liaison for assistance. Publications Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth Hypertension (Dallas, Tex. : 1979). 12, 2021 | Pubmed ID: 34689592 When the Genome Bluffs: a Tandem Duplication Event During Generation of a Novel Agmo Knockout Mouse Model Fools Routine Genotyping Cell & Bioscience. Mar, 2021 | Pubmed ID: 33726865 Isolation and Culture of Murine Bone Marrow-derived Macrophages for Nitric Oxide and Redox Biology Nitric Oxide : Biology and Chemistry. 08, 2020 | Pubmed ID: 32339668 Adipose Tissue-derived WNT5A Regulates Vascular Redox Signaling in Obesity Via USP17/RAC1-mediated Activation of NADPH Oxidases Science Translational Medicine. 09, 2019 | Pubmed ID: 31534019 Publisher Correction: The Metabolite BH4 Controls T Cell Proliferation in Autoimmunity and Cancer Nature. Aug, 2019 | Pubmed ID: 31363232 Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages Through TCA Cycle Regulation and Itaconate Accumulation Cell Reports. 07, 2019 | Pubmed ID: 31269442 Phospholipid Membranes Drive Abdominal Aortic Aneurysm Development Through Stimulating Coagulation Factor Activity Proceedings of the National Academy of Sciences of the United States of America. 04, 2019 | Pubmed ID: 30944221 Improved Cellular Uptake of Perfluorocarbon Nanoparticles for in Vivo Murine Cardiac F MRS/MRI and Temporal Tracking of Progenitor Cells Nanomedicine : Nanotechnology, Biology, and Medicine. 06, 2019 | Pubmed ID: 30448526 Regulation of Mycobacterial Infection by Macrophage Gch1 and Tetrahydrobiopterin Nature Communications. 12, 2018 | Pubmed ID: 30573728 The Metabolite BH4 Controls T cell Proliferation in Autoimmunity and Cancer Nature. 11, 2018 | Pubmed ID: 30405245 Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm Hypertension (Dallas, Tex. : 1979). 07, 2018 | Pubmed ID: 29844152 Roles for Endothelial Cell and Macrophage Gch1 and Tetrahydrobiopterin in Atherosclerosis Progression Cardiovascular Research. 08, 2018 | Pubmed ID: 29596571 Fast, Quantitative, Murine Cardiac 19F MRI/MRS of PFCE-labeled Progenitor Stem Cells and Macrophages at 9.4T PloS One. 2018 | Pubmed ID: 29324754 Metabolic Regulation of Adipose Tissue Macrophage Function in Obesity and Diabetes Antioxidants & Redox Signaling. 07, 2018 | Pubmed ID: 28661198 Endothelium-derived Extracellular Vesicles Promote Splenic Monocyte Mobilization in Myocardial Infarction JCI Insight. 09, 2017 | Pubmed ID: 28878126 A Key Role for Tetrahydrobiopterin-dependent Endothelial NOS Regulation in Resistance Arteries: Studies in Endothelial Cell Tetrahydrobiopterin-deficient Mice British Journal of Pharmacology. 04, 2017 | Pubmed ID: 28128438 Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel HCD68GFP/ApoE-/- Reporter Mouse-Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2017 | Pubmed ID: 27908893 Acute Exposure to Apolipoprotein A1 Inhibits Macrophage Chemotaxis in Vitro and Monocyte Recruitment in Vivo ELife. 08, 2016 | Pubmed ID: 27572261 Endothelial Cell Tetrahydrobiopterin Deficiency Attenuates LPS-induced Vascular Dysfunction and Hypotension Vascular Pharmacology. Feb, 2016 | Pubmed ID: 26276526 Hydrodynamic Gene Delivery of CC Chemokine Binding Fc Fusion Proteins to Target Acute Vascular Inflammation In Vivo Scientific Reports. Dec, 2015 | Pubmed ID: 26620767 RGS1 Regulates Myeloid Cell Accumulation in Atherosclerosis and Aortic Aneurysm Rupture Through Altered Chemokine Signalling Nature Communications. Mar, 2015 | Pubmed ID: 25782711 Tetrahydrobiopterin and Alkylglycerol Monooxygenase Substantially Alter the Murine Macrophage Lipidome Proceedings of the National Academy of Sciences of the United States of America. Feb, 2015 | Pubmed ID: 25675482 Regulation of INOS Function and Cellular Redox State by Macrophage Gch1 Reveals Specific Requirements for Tetrahydrobiopterin in NRF2 Activation Free Radical Biology & Medicine. Feb, 2015 | Pubmed ID: 25451639 Fractalkine Promotes Human Monocyte Survival Via a Reduction in Oxidative Stress Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2014 | Pubmed ID: 25359863 Contrasting in Vitro Vs. in Vivo Effects of a Cell Membrane-specific CC-chemokine Binding Protein on Macrophage Chemotaxis Journal of Molecular Medicine (Berlin, Germany). Nov, 2014 | Pubmed ID: 25077938 Human CD68 Promoter GFP Transgenic Mice Allow Analysis of Monocyte to Macrophage Differentiation in Vivo Blood. Oct, 2014 | Pubmed ID: 25030063 Endothelial Cell-specific Reactive Oxygen Species Production Increases Susceptibility to Aortic Dissection Circulation. Jun, 2014 | Pubmed ID: 24807872 Cell-autonomous Role of Endothelial GTP Cyclohydrolase 1 and Tetrahydrobiopterin in Blood Pressure Regulation Hypertension (Dallas, Tex. : 1979). Sep, 2014 | Pubmed ID: 24777984 Tetrahydrobiopterin in Cardiovascular Health and Disease Antioxidants & Redox Signaling. Jun, 2014 | Pubmed ID: 24294830 Tetrahydrobiopterin Determines Vascular Remodeling Through Enhanced Endothelial Cell Survival and Regeneration Circulation. Sep, 2013 | Pubmed ID: 24030421 The Downstream Regulation of Chemokine Receptor Signalling: Implications for Atherosclerosis Mediators of Inflammation. 2013 | Pubmed ID: 23690662 A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles Amongst Different Primary Murine Macrophages PloS One. 2013 | Pubmed ID: 23516549 The Role of Tetrahydrobiopterin in Inflammation and Cardiovascular Disease Thrombosis and Haemostasis. Nov, 2012 | Pubmed ID: 23052970 Endothelial Cell Repopulation After Stenting Determines In-stent Neointima Formation: Effects of Bare-metal Vs. Drug-eluting Stents and Genetic Endothelial Cell Modification European Heart Journal. Sep, 2012 | Pubmed ID: 23008511 Site-directed Mutagenesis of the CC Chemokine Binding Protein 35K-Fc Reveals Residues Essential for Activity and Mutations That Increase the Potency of CC Chemokine Blockade Molecular Pharmacology. Aug, 2011 | Pubmed ID: 21586597 Inflammatory Cell Recruitment in Cardiovascular Disease: Murine Models and Potential Clinical Applications Clinical Science (London, England : 1979). Mar, 2010 | Pubmed ID: 20210786 RVX-208, a Stimulator of Apolipoprotein AI Gene Expression for the Treatment of Cardiovascular Diseases Current Opinion in Investigational Drugs (London, England : 2000). Mar, 2010 | Pubmed ID: 20178050 Anti-inflammatory Effects of Nicotinic Acid in Adipocytes Demonstrated by Suppression of Fractalkine, RANTES, and MCP-1 and Upregulation of Adiponectin Atherosclerosis. Mar, 2010 | Pubmed ID: 19781706 CCR2-mediated Antiinflammatory Effects of Endothelial Tetrahydrobiopterin Inhibit Vascular Injury-induced Accelerated Atherosclerosis Circulation. Sep, 2008 | Pubmed ID: 18824773 Galectin-3 is an Amplifier of Inflammation in Atherosclerotic Plaque Progression Through Macrophage Activation and Monocyte Chemoattraction Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2008 | Pubmed ID: 18096829 Isolasjon og in vitro kultur av benmarg-avledede makrofager for studiet av NO-Redox Biologi Marina Diotallevi*1,2, Thomas Nicol*1,2, Faseeha Ayaz1,2, Jade Bailey1,2, Andrew Shaw1,2, Eileen McNeill1,2, Ben Davies1,2, Keith M. Channon1,2, Mark J. Crabtree1,2 1BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, 2Wellcome Centre for Human Genetics, University of Oxford JoVE 62834 Immunology and Infection
Isolasjon og in vitro kultur av benmarg-avledede makrofager for studiet av NO-Redox Biologi Marina Diotallevi*1,2, Thomas Nicol*1,2, Faseeha Ayaz1,2, Jade Bailey1,2, Andrew Shaw1,2, Eileen McNeill1,2, Ben Davies1,2, Keith M. Channon1,2, Mark J. Crabtree1,2 1BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, 2Wellcome Centre for Human Genetics, University of Oxford JoVE 62834 Immunology and Infection
