Eric T. Wong Brain Tumor Center and Neuro-Oncology Unit, Department of Neurology Harvard Medical School, Beth Israel Deaconess Medical Center Biography Publications Institution JoVE Articles Eric T. Wong has not added a biography. If you are Eric T. Wong and would like to personalize this page please email our Author Liaison for assistance. Publications Everolimus Shortens Survival of Newly Diagnosed Glioblastoma Patients Journal of Neuro-oncology. Oct, 2018 | Pubmed ID: 29956084 Phase I Study of Low-dose Metronomic Temozolomide for Recurrent Malignant Gliomas BMC Cancer. 11, 2016 | Pubmed ID: 27876012 A Randomized, Placebo-controlled Pilot Trial of Armodafinil for Fatigue in Patients with Gliomas Undergoing Radiotherapy Neuro-oncology. Jun, 2016 | Pubmed ID: 26902850 Neurological Presentations of Intravascular Lymphoma (IVL): Meta-analysis of 654 Patients BMC Neurology. 2016 | Pubmed ID: 26849888 An Overview of Alternating Electric Fields Therapy (NovoTTF Therapy) for the Treatment of Malignant Glioma Current Neurology and Neuroscience Reports. Jan, 2016 | Pubmed ID: 26739692 Clinical Use of Tumor Treating Fields: Discussion Clinical Advances in Hematology & Oncology : H&O. Nov, 2015 | Pubmed ID: 26862773 Clinical Use of Tumor Treating Fields and Other New Technologies in Cancer Clinical Advances in Hematology & Oncology : H&O. Nov, 2015 | Pubmed ID: 26862771 Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection Journal of Oncology. 2015 | Pubmed ID: 26681942 Dosimetric Analysis of the Alopecia Preventing Effect of Hippocampus Sparing Whole Brain Radiation Therapy Radiation Oncology (London, England). 2015 | Pubmed ID: 26611656 Computational Identification of MoRFs in Protein Sequences Using Hierarchical Application of Bayes Rule PloS One. 2015 | Pubmed ID: 26517836 Tumor Treating Fields Therapy Device for Glioblastoma: Physics and Clinical Practice Considerations Expert Review of Medical Devices. 2015 | Pubmed ID: 26513694 Stereotactic Radiosurgery for Brain Metastases from Malignant Melanoma Surgical Neurology International. 2015 | Pubmed ID: 26392919 Response To: Comment on 'Dexamethasone Exerts Profound Immunologic Interference on Treatment Efficacy for Recurrent Glioblastoma' British Journal of Cancer. Dec, 2015 | Pubmed ID: 26348442 Computed Modeling of Alternating Electric Fields Therapy for Recurrent Glioblastoma Cancer Medicine. Nov, 2015 | Pubmed ID: 26311253 An Evidence-Based Review of Alternating Electric Fields Therapy for Malignant Gliomas Current Treatment Options in Oncology. Aug, 2015 | Pubmed ID: 26143265 Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit PloS One. 2015 | Pubmed ID: 26010837 A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or Without Vandetanib in Newly Diagnosed Glioblastoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2015 | Pubmed ID: 25910950 Brain Metastases in Patients with EGFR-mutated or ALK-rearranged Non-small-cell Lung Cancers Lung Cancer (Amsterdam, Netherlands). Apr, 2015 | Pubmed ID: 25682925 Clinical Benefit in Recurrent Glioblastoma from Adjuvant NovoTTF-100A and TCCC After Temozolomide and Bevacizumab Failure: a Preliminary Observation Cancer Medicine. Mar, 2015 | Pubmed ID: 25620708 A MicroRNA-1280/JAG2 Network Comprises a Novel Biological Target in High-risk Medulloblastoma Oncotarget. Feb, 2015 | Pubmed ID: 25576913 Phase II Study of Monthly Pasireotide LAR (SOM230C) for Recurrent or Progressive Meningioma Neurology. Jan, 2015 | Pubmed ID: 25527270 A Feature Analysis of Lower Solubility Proteins in Three Eukaryotic Systems Journal of Proteomics. Apr, 2015 | Pubmed ID: 25451012 Post Hoc Analyses of Intention-to-treat Population in Phase III Comparison of NovoTTF-100A™ System Versus Best Physician's Choice Chemotherapy Seminars in Oncology. Oct, 2014 | Pubmed ID: 25213871 Response Patterns of Recurrent Glioblastomas Treated with Tumor-treating Fields Seminars in Oncology. Oct, 2014 | Pubmed ID: 25213870 The Natural History of Intravascular Lymphomatosis Cancer Medicine. Aug, 2014 | Pubmed ID: 24931821 Contributors to Contrast Between Glioma and Brain Tissue in Chemical Exchange Saturation Transfer Sensitive Imaging at 3 Tesla NeuroImage. Oct, 2014 | Pubmed ID: 24857712 Resolution of Cystic Enhancement to Add-on Tumor Treating Electric Fields for Recurrent Glioblastoma After Incomplete Response to Bevacizumab Case Reports in Neurology. Jan, 2014 | Pubmed ID: 24847254 Characterization and Management of Dermatologic Adverse Events with the NovoTTF-100A System, a Novel Anti-mitotic Electric Field Device for the Treatment of Recurrent Glioblastoma Seminars in Oncology. Jun, 2014 | Pubmed ID: 24794308 Response Assessment of NovoTTF-100A Versus Best Physician's Choice Chemotherapy in Recurrent Glioblastoma Cancer Medicine. Jun, 2014 | Pubmed ID: 24574359 Melanoma Brain Metastasis Globally Reconfigures Chemokine and Cytokine Profiles in Patient Cerebrospinal Fluid Melanoma Research. Apr, 2014 | Pubmed ID: 24463459 A Roundtable Discussion on the Clinical Challenges and Options for the Treatment of Glioblastoma: Introducing a Novel Modality, TTFields Seminars in Oncology. Dec, 2013 | Pubmed ID: 24331200 On the Importance of Polar Interactions for Complexes Containing Intrinsically Disordered Proteins PLoS Computational Biology. 2013 | Pubmed ID: 23990768 Salinomycin: a Novel Anti-cancer Agent with Known Anti-coccidial Activities Current Medicinal Chemistry. 2013 | Pubmed ID: 23931281 BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 MRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles Molecular Therapy. Nucleic Acids. 2013 | Pubmed ID: 23881452 Neurocognitive Assessment Following Whole Brain Radiation Therapy and Radiosurgery for Patients with Cerebral Metastases Journal of Neurology, Neurosurgery, and Psychiatry. Dec, 2013 | Pubmed ID: 23715918 Steroid-sparing Effect of Corticorelin Acetate in Peritumoral Cerebral Edema is Associated with Improvement in Steroid-induced Myopathy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2013 | Pubmed ID: 23382470 Structure and Intrinsic Disorder in Protein Autoinhibition Structure (London, England : 1993). Mar, 2013 | Pubmed ID: 23375259 Phase I Study of GRN1005 in Recurrent Malignant Glioma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2013 | Pubmed ID: 23349317 Noninvasive Application of Alternating Electric Fields in Glioblastoma: a Fourth Cancer Treatment Modality American Society of Clinical Oncology Educational Book / ASCO. American Society of Clinical Oncology. Meeting. 2012 | Pubmed ID: 24451721 The Role of Brevican in Glioma: Promoting Tumor Cell Motility in Vitro and in Vivo BMC Cancer. 2012 | Pubmed ID: 23253190 Hypofractionated Radiotherapy and Stereotactic Boost with Concurrent and Adjuvant Temozolamide for Glioblastoma in Good Performance Status Elderly Patients - Early Results of a Phase II Trial Frontiers in Oncology. 2012 | Pubmed ID: 23087896 Melanoma Brain Metastasis: Overview of Current Management and Emerging Targeted Therapies Expert Review of Neurotherapeutics. Oct, 2012 | Pubmed ID: 23082737 Superior Semicircular Canal Dehiscence in East Asian Women with Osteoporosis BMC Ear, Nose, and Throat Disorders. 2012 | Pubmed ID: 22831544 NovoTTF-100A: a New Treatment Modality for Recurrent Glioblastoma Expert Review of Neurotherapeutics. Aug, 2012 | Pubmed ID: 22708931 NovoTTF-100A Versus Physician's Choice Chemotherapy in Recurrent Glioblastoma: a Randomised Phase III Trial of a Novel Treatment Modality European Journal of Cancer (Oxford, England : 1990). Sep, 2012 | Pubmed ID: 22608262 Metabolomics of Human Cerebrospinal Fluid Identifies Signatures of Malignant Glioma Molecular & Cellular Proteomics : MCP. Jun, 2012 | Pubmed ID: 22240505 Cyberknife Hypofractionated Stereotactic Radiosurgery (HSRS) of Resection Cavity After Excision of Large Cerebral Metastasis: Efficacy and Safety of an 800 CGy × 3 Daily Fractions Regimen Journal of Neuro-oncology. Feb, 2012 | Pubmed ID: 21879395 Illusion of Stroke: Intravascular Lymphomatosis Reviews in Neurological Diseases. 2011 | Pubmed ID: 22249564 Rare Phenomenon of Extracranial Metastasis of Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2011 | Pubmed ID: 22042941 Treatment Advances for Glioblastoma Expert Review of Neurotherapeutics. Oct, 2011 | Pubmed ID: 21955188 Polyradiculopathies from Schwannomatosis The Open Neuroimaging Journal. 2011 | Pubmed ID: 21643503 The Natural History of Extracranial Metastasis from Glioblastoma Multiforme Journal of Neuro-oncology. Nov, 2011 | Pubmed ID: 21512826 Bevacizumab for Recurrent Glioblastoma Multiforme: a Meta-analysis Journal of the National Comprehensive Cancer Network : JNCCN. Apr, 2011 | Pubmed ID: 21464145 The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells Neuron. Mar, 2011 | Pubmed ID: 21382550 Taming Glioblastoma by Targeting Angiogenesis: 3 Years Later Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2011 | Pubmed ID: 21135277 Updated Response Assessment Criteria for High-grade Gliomas: Response Assessment in Neuro-oncology Working Group Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2010 | Pubmed ID: 20231676 Phase I Study of Vandetanib with Radiotherapy and Temozolomide for Newly Diagnosed Glioblastoma International Journal of Radiation Oncology, Biology, Physics. Sep, 2010 | Pubmed ID: 20137866 RIP1 Activates PI3K-Akt Via a Dual Mechanism Involving NF-kappaB-mediated Inhibition of the MTOR-S6K-IRS1 Negative Feedback Loop and Down-regulation of PTEN Cancer Research. May, 2009 | Pubmed ID: 19435890 A Pilot Safety Study of Lenalidomide and Radiotherapy for Patients with Newly Diagnosed Glioblastoma Multiforme International Journal of Radiation Oncology, Biology, Physics. Jan, 2009 | Pubmed ID: 18513880 Bevacizumab Reverses Cerebral Radiation Necrosis Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2008 | Pubmed ID: 18981459 Antiangiogenesis Treatment for Glioblastoma Multiforme: Challenges and Opportunities Journal of the National Comprehensive Cancer Network : JNCCN. May, 2008 | Pubmed ID: 18492463 Organ Deformation and Dose Coverage in Robotic Respiratory-tracking Radiotherapy International Journal of Radiation Oncology, Biology, Physics. May, 2008 | Pubmed ID: 18406892 Bevacizumab Combined with Irinotecan for Recurrent Glioblastoma Multiforme--improvement over Available Therapy? Nature Clinical Practice. Neurology. May, 2008 | Pubmed ID: 18212790 Cerebrospinal Fluid Matrix Metalloproteinase-9 Increases During Treatment of Recurrent Malignant Gliomas Cerebrospinal Fluid Research. 2008 | Pubmed ID: 18186943 Gefitinib and High-dose Fractionated Radiotherapy for Carcinomatous Encephalitis from Non-small Cell Lung Carcinoma Biologics : Targets & Therapy. Sep, 2007 | Pubmed ID: 19707341 Taming Glioblastoma: Targeting Angiogenesis Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007 | Pubmed ID: 17947716 Matrix Metalloprotease-9 in Cerebrospinal Fluid Correlates with Disease Activity in Lymphomatous Meningitis Clinical Lymphoma & Myeloma. Jan, 2007 | Pubmed ID: 17324339 Cyberknife Radiosurgery for Basal Skull Plasmacytoma Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. Oct, 2006 | Pubmed ID: 17032388 Is Protracted Low-dose Temozolomide Feasible in Glioma Patients? Neurology. Aug, 2006 | Pubmed ID: 16894133 Differential Gene Expression Analysis Reveals Generation of an Autocrine Loop by a Mutant Epidermal Growth Factor Receptor in Glioma Cells Cancer Research. Jan, 2006 | Pubmed ID: 16424019 Tumor Growth, Invasion, and Angiogenesis in Malignant Gliomas Journal of Neuro-oncology. May, 2006 | Pubmed ID: 16314946 Management of Central Nervous System Lymphomas Using Monoclonal Antibodies: Challenges and Opportunities Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2005 | Pubmed ID: 16203815 Monoclonal Antibody Therapy for Central Nervous System Lymphomas: an Emerging Treatment Paradigm Expert Opinion on Pharmacotherapy. Jun, 2005 | Pubmed ID: 15957965 Salvage Therapy for Primary CNS Lymphoma with a Combination of Rituximab and Temozolomide Neurology. Mar, 2005 | Pubmed ID: 15753455 Immunochemotherapy with Rituximab and Temozolomide for Central Nervous System Lymphomas Cancer. Jul, 2004 | Pubmed ID: 15221999 The Role of Topotecan in the Treatment of Brain Metastases The Oncologist. 2004 | Pubmed ID: 14755016 The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma Mercedes M. Riley1,2, Pyay San1, Edwin Lok1, Kenneth D. Swanson1, Eric T. Wong1 1Brain Tumor Center and Neuro-Oncology Unit, Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, 2Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology JoVE 58937 Cancer Research
The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma Mercedes M. Riley1,2, Pyay San1, Edwin Lok1, Kenneth D. Swanson1, Eric T. Wong1 1Brain Tumor Center and Neuro-Oncology Unit, Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, 2Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology JoVE 58937 Cancer Research