Erol Fikrig Department of Internal Medicine Yale University School of Medicine Biography Publications Institution JoVE Articles Erol Fikrig has not added a biography. If you are Erol Fikrig and would like to personalize this page please email our Author Liaison for assistance. Publications Circadian Rhythms Influence the Severity of Sepsis in Mice Via a TLR2-Dependent, Leukocyte-Intrinsic Mechanism Journal of Immunology (Baltimore, Md. : 1950). May, 2018 | Pubmed ID: 29760192 Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection Against Plasmodium Infection in Mice Cell Host & Microbe. 04, 2018 | Pubmed ID: 29649443 Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus Cell Host & Microbe. Apr, 2018 | Pubmed ID: 29606496 Altered Vector Competence in an Experimental Mosquito-mouse Transmission Model of Zika Infection PLoS Neglected Tropical Diseases. Mar, 2018 | Pubmed ID: 29505571 Type I Interferons Instigate Fetal Demise After Zika Virus Infection Science Immunology. Jan, 2018 | Pubmed ID: 29305462 Advances in Serodiagnostic Testing for Lyme Disease Are at Hand Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Mar, 2018 | Pubmed ID: 29228208 Artificial Infection of Ticks with Borrelia Burgdorferi Using a Microinjection Method and Their Detection In Vivo Using Quantitative PCR Targeting FlaB RNA Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29032540 Modulation of the Tick Gut Milieu by a Secreted Tick Protein Favors Borrelia Burgdorferi Colonization Nature Communications. 08, 2017 | Pubmed ID: 28775250 Zika Virus and Sexual Transmission: A New Route of Transmission for Mosquito-borne Flaviviruses The Yale Journal of Biology and Medicine. 06, 2017 | Pubmed ID: 28656018 Nlrp9b Inflammasome Restricts Rotavirus Infection in Intestinal Epithelial Cells Nature. 06, 2017 | Pubmed ID: 28636595 An Essential Role of PI3K in the Control of West Nile Virus Infection Scientific Reports. Jun, 2017 | Pubmed ID: 28623344 Fetal Growth Restriction Caused by Sexual Transmission of Zika Virus in Mice The Journal of Infectious Diseases. Jun, 2017 | Pubmed ID: 28472297 A Tick Antivirulence Protein Potentiates Antibiotics Against Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. 07, 2017 | Pubmed ID: 28438938 TAM Receptors Are Not Required for Zika Virus Infection in Mice Cell Reports. 04, 2017 | Pubmed ID: 28423319 Anti-Biofilm Activity of a Self-Aggregating Peptide Against Frontiers in Microbiology. 2017 | Pubmed ID: 28392782 Zika Virus Causes Testicular Atrophy Science Advances. Feb, 2017 | Pubmed ID: 28261663 Infection-derived Lipids Elicit an Immune Deficiency Circuit in Arthropods Nature Communications. Feb, 2017 | Pubmed ID: 28195158 Multiple UBXN Family Members Inhibit Retrovirus and Lentivirus Production and Canonical NFκΒ Signaling by Stabilizing IκBα PLoS Pathogens. Feb, 2017 | Pubmed ID: 28152074 Pathogen-mediated Manipulation of Arthropod Microbiota to Promote Infection Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28096373 Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance Journal of Virology. Jan, 2017 | Pubmed ID: 27795421 TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice Journal of Immunology (Baltimore, Md. : 1950). Dec, 2016 | Pubmed ID: 27798161 Aedes Aegypti D7 Saliva Protein Inhibits Dengue Virus Infection PLoS Neglected Tropical Diseases. Sep, 2016 | Pubmed ID: 27632170 Zika Virus Productively Infects Primary Human Placenta-specific Macrophages JCI Insight. Aug, 2016 | Pubmed ID: 27595140 A Novel Mosquito Ubiquitin Targets Viral Envelope Protein for Degradation and Reduces Virion Production During Dengue Virus Infection Biochimica Et Biophysica Acta. 09, 2016 | Pubmed ID: 27241849 Genetics of War and Truce Between Mosquitos and Emerging Viruses Cell Host & Microbe. May, 2016 | Pubmed ID: 27173926 Variable Major Proteins As Targets for Specific Antibodies Against Borrelia Miyamotoi Journal of Immunology (Baltimore, Md. : 1950). 05, 2016 | Pubmed ID: 27076681 Ixodes Scapularis Dystroglycan-like Protein Promotes Borrelia Burgdorferi Migration from the Gut Journal of Molecular Medicine (Berlin, Germany). Mar, 2016 | Pubmed ID: 26594018 Nlrp6 Regulates Intestinal Antiviral Innate Immunity Science (New York, N.Y.). Nov, 2015 | Pubmed ID: 26494172 Dengue Virus Infection of Aedes Aegypti Requires a Putative Cysteine Rich Venom Protein PLoS Pathogens. Oct, 2015 | Pubmed ID: 26491875 Tick Microbiome: the Force Within Trends in Parasitology. Jul, 2015 | Pubmed ID: 25936226 Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers Journal of Virology. May, 2015 | Pubmed ID: 25740989 Frostbite Protection in Mice Expressing an Antifreeze Glycoprotein PloS One. 2015 | Pubmed ID: 25714402 Role of the Vector in Arbovirus Transmission Annual Review of Virology. Nov, 2014 | Pubmed ID: 26958715 Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders Journal of Aging Science. Jan, 2014 | Pubmed ID: 25750929 Antivirulence Properties of an Antifreeze Protein Cell Reports. Oct, 2014 | Pubmed ID: 25373896 A Tick Gut Protein with Fibronectin III Domains Aids Borrelia Burgdorferi Congregation to the Gut During Transmission PLoS Pathogens. Aug, 2014 | Pubmed ID: 25102051 Innexin AGAP001476 is Critical for Mediating Anti-Plasmodium Responses in Anopheles Mosquitoes The Journal of Biological Chemistry. Sep, 2014 | Pubmed ID: 25035430 Anaplasma Phagocytophilum Surface Protein AipA Mediates Invasion of Mammalian Host Cells Cellular Microbiology. Aug, 2014 | Pubmed ID: 24612118 Gut Microbiota of the Tick Vector Ixodes Scapularis Modulate Colonization of the Lyme Disease Spirochete Cell Host & Microbe. Jan, 2014 | Pubmed ID: 24439898 Mosquito Saliva Serine Protease Enhances Dissemination of Dengue Virus into the Mammalian Host Journal of Virology. Jan, 2014 | Pubmed ID: 24131723 ELF4 is Critical for Induction of Type I Interferon and the Host Antiviral Response Nature Immunology. Dec, 2013 | Pubmed ID: 24185615 Plasmodium Falciparum Phosphoethanolamine Methyltransferase is Essential for Malaria Transmission Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24145416 MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema Pallidum, the Agent of Syphilis PloS One. 2013 | Pubmed ID: 23940747 Identification of Genes Critical for Resistance to Infection by West Nile Virus Using RNA-Seq Analysis Viruses. Jul, 2013 | Pubmed ID: 23881275 Characterization of Ixophilin, a Thrombin Inhibitor from the Gut of Ixodes Scapularis PloS One. 2013 | Pubmed ID: 23874485 Factor Xa Activation of Factor V is of Paramount Importance in Initiating the Coagulation System: Lessons from a Tick Salivary Protein Circulation. Jul, 2013 | Pubmed ID: 23817575 Anopheles Gambiae Circumsporozoite Protein-binding Protein Facilitates Plasmodium Infection of Mosquito Salivary Glands The Journal of Infectious Diseases. Oct, 2013 | Pubmed ID: 23801601 The Lipoprotein La7 Contributes to Borrelia Burgdorferi Persistence in Ticks and Their Transmission to Naïve Hosts Microbes and Infection. Sep-Oct, 2013 | Pubmed ID: 23774694 UBXN1 Interferes with Rig-I-like Receptor-mediated Antiviral Immune Response by Targeting MAVS Cell Reports. Apr, 2013 | Pubmed ID: 23545497 Impaired Toll-like Receptor 3-mediated Immune Responses from Macrophages of Patients Chronically Infected with Hepatitis C Virus Clinical and Vaccine Immunology : CVI. Feb, 2013 | Pubmed ID: 23220997 Anaplasma Phagocytophilum Asp14 is an Invasin That Interacts with Mammalian Host Cells Via Its C Terminus to Facilitate Infection Infection and Immunity. Jan, 2013 | Pubmed ID: 23071137 West Nile Virus: Biology, Transmission, and Human Infection Clinical Microbiology Reviews. Oct, 2012 | Pubmed ID: 23034323 Immunity's Fourth Dimension: Approaching the Circadian-immune Connection Trends in Immunology. Dec, 2012 | Pubmed ID: 23000010 IL-22 Signaling Contributes to West Nile Encephalitis Pathogenesis PloS One. 2012 | Pubmed ID: 22952908 Anaplasma Phagocytophilum Outer Membrane Protein A Interacts with Sialylated Glycoproteins to Promote Infection of Mammalian Host Cells Infection and Immunity. Nov, 2012 | Pubmed ID: 22907813 Semaphorin 7A Contributes to West Nile Virus Pathogenesis Through TGF-β1/Smad6 Signaling Journal of Immunology (Baltimore, Md. : 1950). Sep, 2012 | Pubmed ID: 22896629 Ixodes Scapularis JAK-STAT Pathway Regulates Tick Antimicrobial Peptides, Thereby Controlling the Agent of Human Granulocytic Anaplasmosis The Journal of Infectious Diseases. Oct, 2012 | Pubmed ID: 22859824 Enhanced Survival of Plasmodium-infected Mosquitoes During Starvation PloS One. 2012 | Pubmed ID: 22808193 Receptor Interacting Protein-2 Contributes to Host Defense Against Anaplasma Phagocytophilum Infection FEMS Immunology and Medical Microbiology. Nov, 2012 | Pubmed ID: 22747758 Activation of the RpoN-RpoS Regulatory Pathway During the Enzootic Life Cycle of Borrelia Burgdorferi BMC Microbiology. Mar, 2012 | Pubmed ID: 22443136 Expression of Ixodes Scapularis Antifreeze Glycoprotein Enhances Cold Tolerance in Drosophila Melanogaster PloS One. 2012 | Pubmed ID: 22428051 The Circadian Clock Controls Toll-like Receptor 9-mediated Innate and Adaptive Immunity Immunity. Feb, 2012 | Pubmed ID: 22342842 Serum Antibodies to Whole-cell and Recombinant Antigens of Borrelia Burgdorferi in Cottontail Rabbits Journal of Wildlife Diseases. Jan, 2012 | Pubmed ID: 22247369 Horizontal and Vertical Transmission of West Nile Virus Genotype NY99 by Culex Salinarius and Genotypes NY99 and WN02 by Culex Tarsalis The American Journal of Tropical Medicine and Hygiene. Jan, 2012 | Pubmed ID: 22232464 Age-associated Elevation in TLR5 Leads to Increased Inflammatory Responses in the Elderly Aging Cell. Feb, 2012 | Pubmed ID: 22023165 Circadian Expression of Clock Genes in Mouse Macrophages, Dendritic Cells, and B Cells Brain, Behavior, and Immunity. Mar, 2012 | Pubmed ID: 22019350 Ixodes Scapularis Salivary Gland Protein P11 Facilitates Migration of Anaplasma Phagocytophilum from the Tick Gut to Salivary Glands EMBO Reports. Oct, 2011 | Pubmed ID: 21921936 Dengue Virus Capsid Protein Binds Core Histones and Inhibits Nucleosome Formation in Human Liver Cells PloS One. 2011 | Pubmed ID: 21909430 Alterations in the Aedes Aegypti Transcriptome During Infection with West Nile, Dengue and Yellow Fever Viruses PLoS Pathogens. Sep, 2011 | Pubmed ID: 21909258 A Tick Mannose-binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Cell Host & Microbe. Aug, 2011 | Pubmed ID: 21843870 An in Vivo Transfection Approach Elucidates a Role for Aedes Aegypti Thioester-containing Proteins in Flaviviral Infection PloS One. 2011 | Pubmed ID: 21818390 Innate Immune Control of West Nile Virus Infection Cellular Microbiology. Nov, 2011 | Pubmed ID: 21790942 Use of a Tandem Affinity Purification Assay to Detect Interactions Between West Nile and Dengue Viral Proteins and Proteins of the Mosquito Vector Virology. Aug, 2011 | Pubmed ID: 21700306 PrM-antibody Renders Immature West Nile Virus Infectious in Vivo The Journal of General Virology. Oct, 2011 | Pubmed ID: 21697345 Molecular Interactions That Enable Movement of the Lyme Disease Agent from the Tick Gut into the Hemolymph PLoS Pathogens. Jun, 2011 | Pubmed ID: 21695244 Impaired Interferon Signaling in Dendritic Cells from Older Donors Infected in Vitro with West Nile Virus The Journal of Infectious Diseases. May, 2011 | Pubmed ID: 21398396 Identification and Characterization of Ixodes Scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display PloS One. Jan, 2011 | Pubmed ID: 21246036 Anaplasma Phagocytophilum AptA Modulates Erk1/2 Signalling Cellular Microbiology. Jan, 2011 | Pubmed ID: 20716207 Tick Histamine Release Factor is Critical for Ixodes Scapularis Engorgement and Transmission of the Lyme Disease Agent PLoS Pathogens. Nov, 2010 | Pubmed ID: 21124826 A Paradoxical Role for Neutrophils in the Pathogenesis of West Nile Virus The Journal of Infectious Diseases. Dec, 2010 | Pubmed ID: 21050124 Caspase-12 Controls West Nile Virus Infection Via the Viral RNA Receptor RIG-I Nature Immunology. Oct, 2010 | Pubmed ID: 20818395 A C-type Lectin Collaborates with a CD45 Phosphatase Homolog to Facilitate West Nile Virus Infection of Mosquitoes Cell. Sep, 2010 | Pubmed ID: 20797779 Anaplasma Phagocytophilum Induces Ixodes Scapularis Ticks to Express an Antifreeze Glycoprotein Gene That Enhances Their Survival in the Cold The Journal of Clinical Investigation. Sep, 2010 | Pubmed ID: 20739755 Anaplasma Phagocytophilum Induces Actin Phosphorylation to Selectively Regulate Gene Transcription in Ixodes Scapularis Ticks The Journal of Experimental Medicine. Aug, 2010 | Pubmed ID: 20660616 Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-immunosuppressed Adults PloS One. 2010 | Pubmed ID: 20596538 Fucosylation Enhances Colonization of Ticks by Anaplasma Phagocytophilum Cellular Microbiology. Sep, 2010 | Pubmed ID: 20331643 Age-associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20100933 Passage Through Ixodes Scapularis Ticks Enhances the Virulence of a Weakly Pathogenic Isolate of Borrelia Burgdorferi Infection and Immunity. Jan, 2010 | Pubmed ID: 19822652 The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus Cell. Dec, 2009 | Pubmed ID: 20064371 Antibodies Against a Tick Protein, Salp15, Protect Mice from the Lyme Disease Agent Cell Host & Microbe. Nov, 2009 | Pubmed ID: 19917502 IL-10 Signaling Blockade Controls Murine West Nile Virus Infection PLoS Pathogens. Oct, 2009 | Pubmed ID: 19816558 Toll-like Receptors 1 and 2 Heterodimers Alter Borrelia Burgdorferi Gene Expression in Mice and Ticks The Journal of Infectious Diseases. Oct, 2009 | Pubmed ID: 19754309 Human Innate Immunosenescence: Causes and Consequences for Immunity in Old Age Trends in Immunology. Jul, 2009 | Pubmed ID: 19541535 Fusion Loop Peptide of the West Nile Virus Envelope Protein is Essential for Pathogenesis and is Recognized by a Therapeutic Cross-reactive Human Monoclonal Antibody Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19535627 Inhibition of Neutrophil Function by Two Tick Salivary Proteins Infection and Immunity. Jun, 2009 | Pubmed ID: 19332533 Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis Via Interleukin 23-dependent Immune Cell Infiltration and Homing Immunity. Feb, 2009 | Pubmed ID: 19200759 Anaplasma Phagocytophilum Increases Cathepsin L Activity, Thereby Globally Influencing Neutrophil Function Infection and Immunity. Nov, 2008 | Pubmed ID: 18765732 Borrelia Burgdorferi Lipoprotein BmpA Activates Pro-inflammatory Responses in Human Synovial Cells Through a Protein Moiety Microbes and Infection / Institut Pasteur. Oct, 2008 | Pubmed ID: 18725314 RNA Interference Screen for Human Genes Associated with West Nile Virus Infection Nature. Sep, 2008 | Pubmed ID: 18690214 Drak2 Contributes to West Nile Virus Entry into the Brain and Lethal Encephalitis Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18641347 Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain Journal of Virology. Sep, 2008 | Pubmed ID: 18632868 Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly Journal of Virology. Aug, 2008 | Pubmed ID: 18508883 The Tick Salivary Protein Salp15 Inhibits the Killing of Serum-sensitive Borrelia Burgdorferi Sensu Lato Isolates Infection and Immunity. Jul, 2008 | Pubmed ID: 18426890 West Nile Virus Attenuates Activation of Primary Human Macrophages Viral Immunology. Mar, 2008 | Pubmed ID: 18355125 Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing Both Nucleosome Remodeling and MRNA Stabilization PLoS Pathogens. Feb, 2008 | Pubmed ID: 18282094 Icam-1 Participates in the Entry of West Nile Virus into the Central Nervous System Journal of Virology. Apr, 2008 | Pubmed ID: 18256150 Borrelia Burgdorferi Basic Membrane Proteins A and B Participate in the Genesis of Lyme Arthritis The Journal of Experimental Medicine. Jan, 2008 | Pubmed ID: 18166585 C-Jun NH2-terminal Kinase 2 Inhibits Gamma Interferon Production During Anaplasma Phagocytophilum Infection Infection and Immunity. Jan, 2008 | Pubmed ID: 17998313 West Nile Virus Envelope Protein Inhibits DsRNA-induced Innate Immune Responses Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056386 A Tick Antioxidant Facilitates the Lyme Disease Agent's Successful Migration from the Mammalian Host to the Arthropod Vector Cell Host & Microbe. Jul, 2007 | Pubmed ID: 18005713 Abrogation of Macrophage Migration Inhibitory Factor Decreases West Nile Virus Lethality by Limiting Viral Neuroinvasion The Journal of Clinical Investigation. Oct, 2007 | Pubmed ID: 17909632 ASC/PYCARD and Caspase-1 Regulate the IL-18/IFN-gamma Axis During Anaplasma Phagocytophilum Infection Journal of Immunology (Baltimore, Md. : 1950). Oct, 2007 | Pubmed ID: 17878377 Role of Outer Surface Protein D in the Borrelia Burgdorferi Life Cycle Infection and Immunity. Sep, 2007 | Pubmed ID: 17620358 IL-12/23p40-dependent Clearance of Anaplasma Phagocytophilum in the Murine Model of Human Anaplasmosis FEMS Immunology and Medical Microbiology. Aug, 2007 | Pubmed ID: 17521390 Immunity Against Ixodes Scapularis Salivary Proteins Expressed Within 24 Hours of Attachment Thwarts Tick Feeding and Impairs Borrelia Transmission PloS One. 2007 | Pubmed ID: 17505544 Outer Surface Protein B is Critical for Borrelia Burgdorferi Adherence and Survival Within Ixodes Ticks PLoS Pathogens. Mar, 2007 | Pubmed ID: 17352535 Anaplasma Phagocytophilum Specifically Induces Tyrosine Phosphorylation of ROCK1 During Infection Cellular Microbiology. Jul, 2007 | Pubmed ID: 17346310 Rab 5 is Required for the Cellular Entry of Dengue and West Nile Viruses Journal of Virology. May, 2007 | Pubmed ID: 17301152 Age-associated Defect in Human TLR-1/2 Function Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007 | Pubmed ID: 17202359 The Lyme Disease Agent Borrelia Burgdorferi Requires BB0690, a Dps Homologue, to Persist Within Ticks Molecular Microbiology. Feb, 2007 | Pubmed ID: 17181780 Antiviral Peptides Targeting the West Nile Virus Envelope Protein Journal of Virology. Feb, 2007 | Pubmed ID: 17151121 Cutting Edge: CD4 is the Receptor for the Tick Saliva Immunosuppressor, Salp15 Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006 | Pubmed ID: 17082567 Disruption of the Salivary Protein 14 in Ixodes Scapularis Nymphs and Impact on Pathogen Acquisition The American Journal of Tropical Medicine and Hygiene. Oct, 2006 | Pubmed ID: 17038693 An Ixodes Scapularis Protein Required for Survival of Anaplasma Phagocytophilum in Tick Salivary Glands The Journal of Experimental Medicine. Jun, 2006 | Pubmed ID: 16717118 Borrelia Burgdorferi Lacking BBK32, a Fibronectin-binding Protein, Retains Full Pathogenicity Infection and Immunity. Jun, 2006 | Pubmed ID: 16714558 Gamma Interferon Plays a Crucial Early Antiviral Role in Protection Against West Nile Virus Infection Journal of Virology. Jun, 2006 | Pubmed ID: 16699014 Borrelia Burgdorferi--traveling Incognito? Microbes and Infection. Apr, 2006 | Pubmed ID: 16698304 Early Transcriptional Response of Human Neutrophils to Anaplasma Phagocytophilum Infection Infection and Immunity. Dec, 2005 | Pubmed ID: 16299303 Protective and Therapeutic Capacity of Human Single-chain Fv-Fc Fusion Proteins Against West Nile Virus Journal of Virology. Dec, 2005 | Pubmed ID: 16282460 Effects of Anaplasma Phagocytophilum on Host Cell Ferritin MRNA and Protein Levels Infection and Immunity. Nov, 2005 | Pubmed ID: 16239567 Association of Linear Plasmid 28-1 with an Arthritic Phenotype of Borrelia Burgdorferi Infection and Immunity. Nov, 2005 | Pubmed ID: 16239515 The Lyme Disease Agent Exploits a Tick Protein to Infect the Mammalian Host Nature. Jul, 2005 | Pubmed ID: 16049492 Modulation of NB4 Promyelocytic Leukemic Cell Machinery by Anaplasma Phagocytophilum Genomics. Sep, 2005 | Pubmed ID: 16005178 Use of RNA Interference to Prevent Lethal Murine West Nile Virus Infection The Journal of Infectious Diseases. Apr, 2005 | Pubmed ID: 15747251 Anaplasma Phagocytophilum Modulates Gp91phox Gene Expression Through Altered Interferon Regulatory Factor 1 and PU.1 Levels and Binding of CCAAT Displacement Protein Infection and Immunity. Jan, 2005 | Pubmed ID: 15618156 Toll-like Receptor 3 Mediates West Nile Virus Entry into the Brain Causing Lethal Encephalitis Nature Medicine. Dec, 2004 | Pubmed ID: 15558055 TROSPA, an Ixodes Scapularis Receptor for Borrelia Burgdorferi Cell. Nov, 2004 | Pubmed ID: 15537536 Borrelia Burgdorferi Changes Its Surface Antigenic Expression in Response to Host Immune Responses Infection and Immunity. Oct, 2004 | Pubmed ID: 15385475 A Comparison of Serologic Tests for the Detection of Serum Antibodies to Whole-cell and Recombinant Borrelia Burgdorferi Antigens in Cattle The Canadian Veterinary Journal = La Revue Veterinaire Canadienne. Aug, 2004 | Pubmed ID: 15368740 CXCR2 Blockade Influences Anaplasma Phagocytophilum Propagation but Not Histopathology in the Mouse Model of Human Granulocytic Anaplasmosis Clinical and Diagnostic Laboratory Immunology. Sep, 2004 | Pubmed ID: 15358660 Protective Niche for Borrelia Burgdorferi to Evade Humoral Immunity The American Journal of Pathology. Sep, 2004 | Pubmed ID: 15331421 Anaplasma Phagocytophilum Utilizes Multiple Host Evasion Mechanisms to Thwart NADPH Oxidase-mediated Killing During Neutrophil Infection Infection and Immunity. Aug, 2004 | Pubmed ID: 15271939 Immunity to West Nile Virus Current Opinion in Immunology. Aug, 2004 | Pubmed ID: 15245749 Borrelia Burgdorferi Outer Surface Protein (osp) B Expression Independent of OspA Microbial Pathogenesis. Jul, 2004 | Pubmed ID: 15194158 West Nile Virus: a Growing Concern? The Journal of Clinical Investigation. Apr, 2004 | Pubmed ID: 15085186 Preferential Presence of Decorin-binding Protein B (BBA25) and BBA50 Antibodies in Cerebrospinal Fluid of Patients with Neurologic Lyme Disease Journal of Clinical Microbiology. Mar, 2004 | Pubmed ID: 15004083 Essential Role for OspA/B in the Life Cycle of the Lyme Disease Spirochete The Journal of Experimental Medicine. Mar, 2004 | Pubmed ID: 14981112 OspB Antibody Prevents Borrelia Burgdorferi Colonization of Ixodes Scapularis Infection and Immunity. Mar, 2004 | Pubmed ID: 14977984 Disruption of Ixodes Scapularis Anticoagulation by Using RNA Interference Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14745044 OspC Facilitates Borrelia Burgdorferi Invasion of Ixodes Scapularis Salivary Glands The Journal of Clinical Investigation. Jan, 2004 | Pubmed ID: 14722614 Borrelia Burgdorferi Transcriptome in the Central Nervous System of Non-human Primates Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14671329 Invasion and Survival Strategies of Anaplasma Phagocytophilum Cellular Microbiology. Nov, 2003 | Pubmed ID: 14531890 Immunoassay Targeting Nonstructural Protein 5 to Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination Journal of Clinical Microbiology. Sep, 2003 | Pubmed ID: 12958248 IFN-gamma-producing Gamma Delta T Cells Help Control Murine West Nile Virus Infection Journal of Immunology (Baltimore, Md. : 1950). Sep, 2003 | Pubmed ID: 12928402 Murine Neutrophils Require Alpha1,3-fucosylation but Not PSGL-1 for Productive Infection with Anaplasma Phagocytophilum Blood. Nov, 2003 | Pubmed ID: 12869507 Adaptation of Borrelia Burgdorferi in the Vector and Vertebrate Host Microbes and Infection / Institut Pasteur. Jun, 2003 | Pubmed ID: 12787742 An Open-label, Nonrandomized, Single-center, Prospective Extension, Clinical Trial of Booster Dose Schedules to Assess the Safety Profile and Immunogenicity of Recombinant Outer-surface Protein A (OspA) Lyme Disease Vaccine Clinical Therapeutics. Jan, 2003 | Pubmed ID: 12637121 STAT3 Deletion During Hematopoiesis Causes Crohn's Disease-like Pathogenesis and Lethality: a Critical Role of STAT3 in Innate Immunity Proceedings of the National Academy of Sciences of the United States of America. Feb, 2003 | Pubmed ID: 12571365 The Lyme Disease Vaccine Takes Its Toll Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 2002 | Pubmed ID: 12804162 A Recombinant Envelope Protein-based Enzyme-linked Immunosorbent Assay for West Nile Virus Serodiagnosis Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 2002 | Pubmed ID: 12653304 Repression of Rac2 MRNA Expression by Anaplasma Phagocytophila is Essential to the Inhibition of Superoxide Production and Bacterial Proliferation Journal of Immunology (Baltimore, Md. : 1950). Dec, 2002 | Pubmed ID: 12471136 Cyclooxygenase 2 Activity Modulates the Severity of Murine Lyme Arthritis FEMS Immunology and Medical Microbiology. Nov, 2002 | Pubmed ID: 12423770 Differential Expression of the P44 Gene Family in the Agent of Human Granulocytic Ehrlichiosis Infection and Immunity. Sep, 2002 | Pubmed ID: 12183586 Superoxide Anion Production During Anaplasma Phagocytophila Infection The Journal of Infectious Diseases. Jul, 2002 | Pubmed ID: 12134266 Salp15, an Ixodes Scapularis Salivary Protein, Inhibits CD4(+) T Cell Activation Immunity. Jun, 2002 | Pubmed ID: 12121666 Hyporesponsiveness to Vaccination with Borrelia Burgdorferi OspA in Humans and in TLR1- and TLR2-deficient Mice Nature Medicine. Aug, 2002 | Pubmed ID: 12091878 Murine Lyme Arthritis Development Mediated by P38 Mitogen-activated Protein Kinase Activity Journal of Immunology (Baltimore, Md. : 1950). Jun, 2002 | Pubmed ID: 12055252 Examination of the Borrelia Burgdorferi Transcriptome in Ixodes Scapularis During Feeding Journal of Bacteriology. Jun, 2002 | Pubmed ID: 12003955 Borrelia Burgdorferi-induced Inflammation Facilitates Spirochete Adaptation and Variable Major Protein-like Sequence Locus Recombination Journal of Immunology (Baltimore, Md. : 1950). Sep, 2001 | Pubmed ID: 11544329 Exploitation of Interleukin-8-induced Neutrophil Chemotaxis by the Agent of Human Granulocytic Ehrlichiosis Infection and Immunity. Sep, 2001 | Pubmed ID: 11500432 Dissociation of Infectivity and Pathogenicity in Borrelia Burgdorferi Infection and Immunity. May, 2001 | Pubmed ID: 11292785 Coinfection with Borrelia Burgdorferi and the Agent of Human Granulocytic Ehrlichiosis Alters Murine Immune Responses, Pathogen Burden, and Severity of Lyme Arthritis Infection and Immunity. May, 2001 | Pubmed ID: 11292759 Detection of Ehrlichia Chaffeensis DNA in Amblyomma Americanum Ticks in Connecticut and Rhode Island Journal of Clinical Microbiology. Dec, 2000 | Pubmed ID: 11101616 Attachment of Borrelia Burgdorferi Within Ixodes Scapularis Mediated by Outer Surface Protein A The Journal of Clinical Investigation. Aug, 2000 | Pubmed ID: 10953031 Granulocytic Ehrlichiosis in Mice Deficient in Phagocyte Oxidase or Inducible Nitric Oxide Synthase Infection and Immunity. Jul, 2000 | Pubmed ID: 10858261 Gamma Interferon Dominates the Murine Cytokine Response to the Agent of Human Granulocytic Ehrlichiosis and Helps to Control the Degree of Early Rickettsemia Infection and Immunity. Apr, 2000 | Pubmed ID: 10722570 Borrelia Burgdorferi Gene Expression in Vivo and Spirochete Pathogenicity Infection and Immunity. Mar, 2000 | Pubmed ID: 10678930 Serodiagnosis of Human Granulocytic Ehrlichiosis by a Recombinant HGE-44-based Enzyme-linked Immunosorbent Assay Journal of Clinical Microbiology. Nov, 1999 | Pubmed ID: 10523549 Influence of Outer Surface Protein A Antibody on Borrelia Burgdorferi Within Feeding Ticks Infection and Immunity. Jan, 1999 | Pubmed ID: 9864192 Cloning of the Gene Encoding the 44-kilodalton Antigen of the Agent of Human Granulocytic Ehrlichiosis and Characterization of the Humoral Response Infection and Immunity. Jul, 1998 | Pubmed ID: 9632594 Heat Shock Protein 70 of the Agent of Human Granulocytic Ehrlichiosis Binds to Borrelia Burgdorferi Antibodies Clinical and Diagnostic Laboratory Immunology. Jan, 1998 | Pubmed ID: 9455892 Interleukin (IL)-6 Directs the Differentiation of IL-4-producing CD4+ T Cells The Journal of Experimental Medicine. Feb, 1997 | Pubmed ID: 9053446 Kene bağırsaklar tarafından bütün-mount Situ hibridizasyon Microbiota görselleştirme Caitlin E. Moss1, Andrew Robson2, Erol Fikrig3, Sukanya Narasimhan3 1Department of Microbial Pathogenesis, Yale University School of Medicine, 2Program in Vertebrate Developmental Biology, Departments of Pediatrics and Genetics, Yale University School of Medicine, 3Department of Internal Medicine, Yale University School of Medicine JoVE 57758 Genetics
Kene bağırsaklar tarafından bütün-mount Situ hibridizasyon Microbiota görselleştirme Caitlin E. Moss1, Andrew Robson2, Erol Fikrig3, Sukanya Narasimhan3 1Department of Microbial Pathogenesis, Yale University School of Medicine, 2Program in Vertebrate Developmental Biology, Departments of Pediatrics and Genetics, Yale University School of Medicine, 3Department of Internal Medicine, Yale University School of Medicine JoVE 57758 Genetics
