Frauke Neff

Publications

• Analysis of Mammalian Gene Function Through Broad-based Phenotypic Screens Across a Consortium of Mouse Clinics
  Nature Genetics. Jul, 2015  |   Pubmed ID: 26214591
• Genetic Disruption of Uncoupling Protein 1 in Mice Renders Brown Adipose Tissue a Significant Source of FGF21 Secretion
  Molecular Metabolism. Jul, 2015  |   Pubmed ID: 26137441
• Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery
  Molecular Cancer Therapeutics. Aug, 2015  |   Pubmed ID: 26063765
• MiR-34a Deficiency Accelerates Medulloblastoma Formation in Vivo
  International Journal of Cancer. Journal International Du Cancer. May, 2015  |   Pubmed ID: 25348795
• The Cognitive Defects of Neonatally Irradiated Mice Are Accompanied by Changed Synaptic Plasticity, Adult Neurogenesis and Neuroinflammation
  Molecular Neurodegeneration. 2014  |   Pubmed ID: 25515237
• MTO1-deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy
  PloS One. 2014  |   Pubmed ID: 25506927
• Inactivation of the Ferroptosis Regulator Gpx4 Triggers Acute Renal Failure in Mice
  Nature Cell Biology. Dec, 2014  |   Pubmed ID: 25402683
• Calcitonin Controls Bone Formation by Inhibiting the Release of Sphingosine 1-phosphate from Osteoclasts
  Nature Communications. 2014  |   Pubmed ID: 25333900
• Pleiotropic Functions for Transcription Factor Zscan10
  PloS One. 2014  |   Pubmed ID: 25111779
• Longevity, Aging and Rapamycin
  Cellular and Molecular Life Sciences : CMLS. Nov, 2014  |   Pubmed ID: 25015322
• Multimodality Multiparametric Imaging of Early Tumor Response to a Novel Antiangiogenic Therapy Based on Anticalins
  PloS One. 2014  |   Pubmed ID: 24801709
• Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43
  The Journal of Biological Chemistry. Apr, 2014  |   Pubmed ID: 24515116
• Gene Trap Mice Reveal an Essential Function of Dual Specificity Phosphatase Dusp16/MKP-7 in Perinatal Survival and Regulation of Toll-like Receptor (TLR)-induced Cytokine Production
  The Journal of Biological Chemistry. Jan, 2014  |   Pubmed ID: 24311790
• The Zyxin-related Protein Thyroid Receptor Interacting Protein 6 (TRIP6) is Overexpressed in Ewing's Sarcoma and Promotes Migration, Invasion and Cell Growth
  Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Nov, 2013  |   Pubmed ID: 24033704
• A Comparative Phenotypic and Genomic Analysis of C57BL/6J and C57BL/6N Mouse Strains
  Genome Biology. Jul, 2013  |   Pubmed ID: 23902802
• Rapamycin Extends Murine Lifespan but Has Limited Effects on Aging
  The Journal of Clinical Investigation. Aug, 2013  |   Pubmed ID: 23863708
• An ENU Mutagenesis-derived Mouse Model with a Dominant Jak1 Mutation Resembling Phenotypes of Systemic Autoimmune Disease
  The American Journal of Pathology. Aug, 2013  |   Pubmed ID: 23791841
• Roquin Paralogs 1 and 2 Redundantly Repress the Icos and Ox40 Costimulator MRNAs and Control Follicular Helper T Cell Differentiation
  Immunity. Apr, 2013  |   Pubmed ID: 23583643
• 독일 마우스 병원에서 마우스 모델의 형질에 혁신
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Oct, 2012  |   Pubmed ID: 22926221
• Srgap3⁻/⁻ Mice Present a Neurodevelopmental Disorder with Schizophrenia-related Intermediate Phenotypes
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2012  |   Pubmed ID: 22820399
• Cytochrome C Oxidase Subunit 4 Isoform 2-knockout Mice Show Reduced Enzyme Activity, Airway Hyporeactivity, and Lung Pathology
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2012  |   Pubmed ID: 22730437
• Large-scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System
  PloS One. 2012  |   Pubmed ID: 22701626
• Small-animal PET Imaging of Amyloid-beta Plaques with [11C]PiB and Its Multi-modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease
  PloS One. 2012  |   Pubmed ID: 22427802
• Label-free Protein Profiling of Formalin-fixed Paraffin-embedded (FFPE) Heart Tissue Reveals Immediate Mitochondrial Impairment After Ionising Radiation
  Journal of Proteomics. Apr, 2012  |   Pubmed ID: 22387116
• Therapeutic Efficacy and Toxicity of 225Ac-labelled Vs. 213Bi-labelled Tumour-homing Peptides in a Preclinical Mouse Model of Peritoneal Carcinomatosis
  European Journal of Nuclear Medicine and Molecular Imaging. Apr, 2012  |   Pubmed ID: 22237842
• STEAP1 is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors
  Molecular Cancer Research : MCR. Jan, 2012  |   Pubmed ID: 22080479
• Loss of Roquin Induces Early Death and Immune Deregulation but Not Autoimmunity
  The Journal of Experimental Medicine. Aug, 2011  |   Pubmed ID: 21844204
• 신속한 Proteomic 몸 전체 전리 방사선으로 인 한 심장 조직을 리 모델링
  Proteomics. Aug, 2011  |   Pubmed ID: 21751382
• Naturally Occurring Autoantibodies Against Beta-amyloid: Investigating Their Role in Transgenic Animal and in Vitro Models of Alzheimer's Disease
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2011  |   Pubmed ID: 21490226
• Validation of Preclinical Multiparametric Imaging for Prediction of Necrosis in Hepatocellular Carcinoma After Embolization
  Journal of Hepatology. Nov, 2011  |   Pubmed ID: 21354233
• Mouse Phenotyping
  Methods (San Diego, Calif.). Feb, 2011  |   Pubmed ID: 20708688
• Pheochromocytoma in Rats with Multiple Endocrine Neoplasia (MENX) Shares Gene Expression Patterns with Human Pheochromocytoma
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010  |   Pubmed ID: 20937862
• Intravenous Immunoglobulins As a Treatment for Alzheimer's Disease: Rationale and Current Evidence
  Drugs. Mar, 2010  |   Pubmed ID: 20329802
• The Role of Macrophage Migration Inhibitory Factor in Alzheimer's Disease
  Molecular Medicine (Cambridge, Mass.). Mar, 2010  |   Pubmed ID: 20200619
• APP Transgenic Mice: the Effect of Active and Passive Immunotherapy in Cognitive Tasks
  Neuroscience and Biobehavioral Reviews. Mar, 2010  |   Pubmed ID: 19857518
• Immunization As Treatment for Parkinson's Disease
  Journal of Neural Transmission. Supplementum. 2009  |   Pubmed ID: 20411789
• Y-box-binding Protein YB-1 Identifies High-risk Patients with Primary Breast Cancer Benefiting from Rapidly Cycled Tandem High-dose Adjuvant Chemotherapy
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2009  |   Pubmed ID: 19901122
• Centrosome Abnormalities in Head and Neck Squamous Cell Carcinoma (HNSCC)
  Acta Oto-laryngologica. Feb, 2009  |   Pubmed ID: 18607971
• [Therapy of Alzheimer's Disease: Current Status and Future Development]
  Neuropsychiatrie : Klinik, Diagnostik, Therapie Und Rehabilitation : Organ Der Gesellschaft Österreichischer Nervenärzte Und Psychiater. 2008  |   Pubmed ID: 18826870
• Immunotherapy and Naturally Occurring Autoantibodies in Neurodegenerative Disorders
  Autoimmunity Reviews. Jun, 2008  |   Pubmed ID: 18558370
• Systemic Inflammatory Response Syndrome Increases Immobility-induced Neuromuscular Weakness
  Critical Care Medicine. Mar, 2008  |   Pubmed ID: 18431280
• A 35-year-old Woman with an Intrasellar and Suprasellar Lesion
  Brain Pathology (Zurich, Switzerland). Jan, 2008  |   Pubmed ID: 18226104
• Evaluation of a Fibroelastoma with Magnetic Resonance Imaging
  European Heart Journal. Jun, 2008  |   Pubmed ID: 18174204
• 기능성 다형성 Plasminogen Activator Urokinase (플 라우) 내에서 알 츠 하이 머 병에 연결 됩니다
  Human Molecular Genetics. Aug, 2006  |   Pubmed ID: 16825285
• Regional Vulnerability of Mesencephalic Dopaminergic Neurons Prone to Degenerate in Parkinson's Disease: a Post-mortem Study in Human Control Subjects
  Neurobiology of Disease. Aug, 2006  |   Pubmed ID: 16753304
• Neurologic Outcome After Cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest in Rats: Description of a New Model
  The Journal of Thoracic and Cardiovascular Surgery. Apr, 2006  |   Pubmed ID: 16580438
• Gene Expression Profiling of Lewy Body-bearing Neurons in Parkinson's Disease
  Experimental Neurology. Sep, 2005  |   Pubmed ID: 15944136
• Serial Induction of Mutations by Ethylnitrosourea in PC12 Cells: a New Model for a Phenotypical Characterization of the Neurotoxic Response to 6-hydroxydopamine
  Journal of Neuroscience Methods. Aug, 2004  |   Pubmed ID: 15262063
• Gene Expression Profiles Derived from Single Cells in Human Postmortem Brain
  Brain Research. Brain Research Protocols. Apr, 2004  |   Pubmed ID: 15063837