Fumihiro Sugiyama

Publications

• A Degron System Targeting Endogenous PD-1 Inhibits the Growth of Tumor Cells in Mice
  NAR Cancer. Jun, 2022  |   Pubmed ID: 35734392
• Birth of Mice from Meiotically Arrested Spermatocytes Following Biparental Meiosis in Halved Oocytes
  EMBO Reports. May, 2022  |   Pubmed ID: 35587095
• L17ER4: A Cell-permeable Attenuated Cationic Amphiphilic Lytic Peptide
  Bioorganic & Medicinal Chemistry. 05, 2022  |   Pubmed ID: 35395514
• Inducible Systemic Deletion in Mice Leads to Transient Body Weight Loss Upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage
  International Journal of Molecular Sciences. Mar, 2022  |   Pubmed ID: 35328622
• In Vitro and in Vivo Functions of T Cells Produced in Complemented Thymi of Chimeric Mice Generated by Blastocyst Complementation
  Scientific Reports. 02, 2022  |   Pubmed ID: 35217706
• DAJIN Enables Multiplex Genotyping to Simultaneously Validate Intended and Unintended Target Genome Editing Outcomes
  PLoS Biology. 01, 2022  |   Pubmed ID: 35041655
• Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction
  Cancers. Aug, 2021  |   Pubmed ID: 34439392
• Relationships Between and Osteoclastogenesis
  Comparative Medicine. 08, 2021  |   Pubmed ID: 34301346
• Efficient Induction of Proximity-dependent Labelling by Biotin Feeding in BMAL1-BioID Knock-in Mice
  Journal of Biochemistry. Dec, 2021  |   Pubmed ID: 33982090
• EXOC1 Plays an Integral Role in Spermatogonia Pseudopod Elongation and Spermatocyte Stable Syncytium Formation in Mice
  ELife. 05, 2021  |   Pubmed ID: 33973520
• Disruption of Entire Locus Leads to Embryonic Lethality by Diminished Gene Expression and Enhanced P53 Pathway
  ELife. 05, 2021  |   Pubmed ID: 33949947
• Response to Correspondence on "Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation"
  Genome Biology. 04, 2021  |   Pubmed ID: 33827648
• Induction of Mutant Allele in Neurons in Late Infancy Increases Sleep Need
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 03, 2021  |   Pubmed ID: 33558433
• Majority of Alpha2,6-sialylated Glycans in the Adult Mouse Brain Exist in O-glycans: SALSA-MS Analysis for Knockout Mice of Alpha2,6-sialyltransferase Genes
  Glycobiology. 06, 2021  |   Pubmed ID: 33242079
• Characterization of a Bicistronic Knock-in Reporter Mouse Model for Investigating the Role of CABLES2 in Vivo
  Experimental Animals. Feb, 2021  |   Pubmed ID: 32779618
• Efficient Production of Large Deletion and Gene Fragment Knock-in Mice Mediated by Genome Editing with Cas9-mouse Cdt1 in Mouse Zygotes
  Methods (San Diego, Calif.). 07, 2021  |   Pubmed ID: 32334080
• Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying P38 Signal in the Lungs
  International Journal of Molecular Sciences. Sep, 2020  |   Pubmed ID: 32937976
• Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β
  Genetics. 11, 2020  |   Pubmed ID: 32878901
• Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine DR-mediated Sleep Reduction
  IScience. Jun, 2020  |   Pubmed ID: 32563157
• Optimizing Charge Switching in Membrane Lytic Peptides for Endosomal Release of Biomacromolecules
  Angewandte Chemie (International Ed. in English). 11, 2020  |   Pubmed ID: 32557993
• Reverse Genetics Reveals Single Gene of Every Candidate on Hybrid Sterility, X Chromosome QTL 2 (Hstx2) Are Dispensable for Spermatogenesis
  Scientific Reports. 06, 2020  |   Pubmed ID: 32493902
• Ribosome Binding Protein GCN1 regulates the Cell Cycle and Cell Proliferation and is Essential for the Embryonic Development of Mice
  PLoS Genetics. 04, 2020  |   Pubmed ID: 32324833
• Generation of B6-Ddx4 , a Novel CreERT2 Knock-in Line, for Germ Cell Lineage by CRISPR/Cas9
  Genesis (New York, N.Y. : 2000). 07, 2020  |   Pubmed ID: 32293787
• Highly Efficient CRISPR-targeting of the Murine Hipp11 Intergenic Region Supports Inducible Human Transgene Expression
  Molecular Biology Reports. Feb, 2020  |   Pubmed ID: 31811500
• Regulation of Bile Acid Metabolism in Mouse Models with Hydrophobic Bile Acid Composition
  Journal of Lipid Research. 01, 2020  |   Pubmed ID: 31645370
• Clec10a Regulates Mite-induced Dermatitis
  Science Immunology. 12, 2019  |   Pubmed ID: 31811054
• Non-invasive in Vivo Imaging of UCP1 Expression in Live Mice Via Near-infrared Fluorescent Protein IRFP720
  PloS One. 2019  |   Pubmed ID: 31730675
• Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation
  Genome Biology. 08, 2019  |   Pubmed ID: 31446895
• Generation of Bicistronic Reporter Knockin Mice for Visualizing Germ Layers
  Experimental Animals. Nov, 2019  |   Pubmed ID: 31189761
• Corrigendum to "Enhancing Endogenous Adenosine A Receptor Signaling Induces Slow-wave Sleep Without Affecting Body Temperature and Cardiovascular Function" [Neuropharmacology 144 (2019) 122-132]
  Neuropharmacology. Jul, 2019  |   Pubmed ID: 31101360
• The Chromatin-binding Protein Phf6 Restricts the Self-renewal of Hematopoietic Stem Cells
  Blood. 06, 2019  |   Pubmed ID: 30917958
• Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche
  Cell Stem Cell. 01, 2019  |   Pubmed ID: 30581080
• Enhancing Endogenous Adenosine A Receptor Signaling Induces Slow-wave Sleep Without Affecting Body Temperature and Cardiovascular Function
  Neuropharmacology. 01, 2019  |   Pubmed ID: 30336152
• Role of Anti-Fractalkine Antibody in Suppression of Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis
  Arthritis & Rheumatology (Hoboken, N.J.). 02, 2019  |   Pubmed ID: 30079992
• A Single Phosphorylation Site of SIK3 Regulates Daily Sleep Amounts and Sleep Need in Mice
  Proceedings of the National Academy of Sciences of the United States of America. 10, 2018  |   Pubmed ID: 30254177
• De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome
  American Journal of Human Genetics. 09, 2018  |   Pubmed ID: 30146126
• A Mutation in Transcription Factor MAFB Causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome
  Kidney International. 08, 2018  |   Pubmed ID: 29779709
• Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis
  Frontiers in Immunology. 2017  |   Pubmed ID: 29387068
• Simple Generation of Hairless Mice for in Vivo Imaging
  Experimental Animals. Oct, 2017  |   Pubmed ID: 28717054
• Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress
  Cell Reports. 02, 2017  |   Pubmed ID: 28228267
• SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells
  Stem Cell Reports. 03, 2017  |   Pubmed ID: 28196692
• Angiodysplasia in Embryo Lacking Protein Arginine Methyltransferase 1 in Vascular Endothelial Cells
  Journal of Biochemistry. Mar, 2017  |   Pubmed ID: 28003433
• Forward-genetics Analysis of Sleep in Randomly Mutagenized Mice
  Nature. 11, 2016  |   Pubmed ID: 27806374
• H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells
  Stem Cell Reports. 06, 2016  |   Pubmed ID: 27237376
• Germline Recombination in a Novel Cre Transgenic Line, Prl3b1-Cre Mouse
  Genesis (New York, N.Y. : 2000). 07, 2016  |   Pubmed ID: 27124574
• Generation of CRISPR/Cas9-mediated Bicistronic Knock-in Ins1-cre Driver Mice
  Experimental Animals. Jul, 2016  |   Pubmed ID: 27053096
• Sialylation Converts Arthritogenic IgG into Inhibitors of Collagen-induced Arthritis
  Nature Communications. Apr, 2016  |   Pubmed ID: 27046227
• β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development
  PloS One. 2016  |   Pubmed ID: 26901059
• Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells
  Stem Cells (Dayton, Ohio). Feb, 2016  |   Pubmed ID: 26523946
• Peri-implantation Lethality in Mice Carrying Megabase-scale Deletion on 5qc3.3 is Caused by Exoc1 Null Mutation
  Scientific Reports. Sep, 2015  |   Pubmed ID: 26346620
• Spatial Interplay Between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes
  Molecular and Cellular Biology. Nov, 2015  |   Pubmed ID: 26324324
• Erythropoiesis and Blood Pressure Are Regulated Via AT1 Receptor by Distinctive Pathways
  PloS One. 2015  |   Pubmed ID: 26107632
• Simple Generation of Albino C57BL/6J Mice with G291T Mutation in the Tyrosinase Gene by the CRISPR/Cas9 System
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 2014  |   Pubmed ID: 24879364
• Generation and Characterization of Ins1-cre-driver C57BL/6N for Exclusive Pancreatic Beta Cell-specific Cre-loxP Recombination
  Experimental Animals. 2014  |   Pubmed ID: 24770644
• A Mouse Renin Distal Enhancer is Essential for Blood Pressure Homeostasis in BAC-rescued Renin-null Mutant Mice
  Journal of Receptor and Signal Transduction Research. Oct, 2014  |   Pubmed ID: 24734888
• Truncated Cables1 Causes Agenesis of the Corpus Callosum in Mice
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Mar, 2014  |   Pubmed ID: 24336072
• Novel ROSA26 Cre-reporter Knock-in C57BL/6N Mice Exhibiting Green Emission Before and Red Emission After Cre-mediated Recombination
  Experimental Animals. 2013  |   Pubmed ID: 24172193
• Effect of Lactation on Postpartum Cardiac Function of Pregnancy-associated Hypertensive Mice
  Endocrinology. Feb, 2013  |   Pubmed ID: 23254193
• Short-term Suppression of the Renin-angiotensin System in Mice Associated with Hypertension During Pregnancy
  Molecular Medicine Reports. 07, 2012  |   Pubmed ID: 22552605
• Pregnancy-associated Homeostasis and Dysregulation: Lessons from Genetically Modified Animal Models
  Journal of Biochemistry. Jul, 2011  |   Pubmed ID: 21613291
• Retrotransposon-mediated Fgf5(go-Utr) Mutant Mice with Long Pelage Hair
  Experimental Animals. 2011  |   Pubmed ID: 21512271
• Simultaneous Detection of Antibodies to Mouse Hepatitis Virus Recombinant Structural Proteins by a Microsphere-based Multiplex Fluorescence Immunoassay
  Clinical and Vaccine Immunology : CVI. May, 2011  |   Pubmed ID: 21430123
• Genome-wide Analysis of Target Genes Regulated by HoxB4 in Hematopoietic Stem and Progenitor Cells Developing from Embryonic Stem Cells
  Blood. Apr, 2011  |   Pubmed ID: 21343615
• Effect of Different Culture Conditions on Establishment of Embryonic Stem Cells from BALB/cAJ and NZB/BINJ Mice
  Cellular Reprogramming. Dec, 2010  |   Pubmed ID: 20977302
• A Novel Locus on Proximal Chromosome 18 Associated with Agenesis of the Corpus Callosum in Mice
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2010  |   Pubmed ID: 20967545
• Autotaxin/lysophospholipase D-mediated Lysophosphatidic Acid Signaling is Required to Form Distinctive Large Lysosomes in the Visceral Endoderm Cells of the Mouse Yolk Sac
  The Journal of Biological Chemistry. Nov, 2009  |   Pubmed ID: 19808661
• Genetic Analysis of Blood Pressure in 8 Mouse Intercross Populations
  Hypertension (Dallas, Tex. : 1979). Oct, 2009  |   Pubmed ID: 19652078
• Angiotensin Type 1 Receptor Blockade Prevents Cardiac Remodeling in Mice with Pregnancy-associated Hypertension
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Dec, 2008  |   Pubmed ID: 19139606
• Embryonic Stem Cells Derived from C57BL/6J and C57BL/6N Mice
  Comparative Medicine. Aug, 2008  |   Pubmed ID: 18724776
• Deterioration of Atherosclerosis in Mice Lacking Angiotensin II Type 1A Receptor in Bone Marrow-derived Cells
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2008  |   Pubmed ID: 18490898
• Novel Embryonic Stem Cells Expressing TdKaede Protein Photoconvertible from Green to Red Fluorescence
  International Journal of Molecular Medicine. Oct, 2007  |   Pubmed ID: 17786273
• Quantitative Trait Loci Associated with Blood Pressure of Metabolic Syndrome in the Progeny of NZO/HILtJxC3H/HeJ Intercrosses
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 2007  |   Pubmed ID: 17641813
• Development of ELISA Using Recombinant Antigens for Specific Detection of Mouse Parvovirus Infection
  Experimental Animals. Apr, 2006  |   Pubmed ID: 16651694
• Uterine Sensitization-associated Gene-1 (USAG-1), a Novel BMP Antagonist Expressed in the Kidney, Accelerates Tubular Injury
  The Journal of Clinical Investigation. Jan, 2006  |   Pubmed ID: 16341262
• A Novel Subpopulation Lacking Oct4 Expression in the Testicular Side Population
  International Journal of Molecular Medicine. Jan, 2006  |   Pubmed ID: 16328007
• Enhanced Erythropoiesis Mediated by Activation of the Renin-angiotensin System Via Angiotensin II Type 1a Receptor
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2005  |   Pubmed ID: 16223784
• Redox Imbalance in Cystine/glutamate Transporter-deficient Mice
  The Journal of Biological Chemistry. Nov, 2005  |   Pubmed ID: 16144837
• Parvovirus Nonstructural Proteins Induce an Epigenetic Modification Through Histone Acetylation in Host Genes and Revert Tumor Malignancy to Benignancy
  Journal of Virology. Jul, 2005  |   Pubmed ID: 15994782
• Establishment of a New Embryonic Stem Cell Line Derived from C57BL/6 Mouse Expressing EGFP Ubiquitously
  Genesis (New York, N.Y. : 2000). May, 2005  |   Pubmed ID: 15830376
• Neurochondrin Negatively Regulates CaMKII Phosphorylation, and Nervous System-specific Gene Disruption Results in Epileptic Seizure
  The Journal of Biological Chemistry. May, 2005  |   Pubmed ID: 15790563
• Differential Roles of Renin and Angiotensinogen in the Feto-maternal Interface in the Development of Complications of Pregnancy
  Molecular Endocrinology (Baltimore, Md.). May, 2005  |   Pubmed ID: 15695374
• Blood Pressure in 15 Inbred Mouse Strains and Its Lack of Relation with Obesity and Insulin Resistance in the Progeny of an NZO/HILtJ X C3H/HeJ Intercross
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2004  |   Pubmed ID: 15599552
• Regulatory Roles for APJ, a Seven-transmembrane Receptor Related to Angiotensin-type 1 Receptor in Blood Pressure in Vivo
  The Journal of Biological Chemistry. Jun, 2004  |   Pubmed ID: 15087458
• An Essential Role for Angiotensin II Type 1a Receptor in Pregnancy-associated Hypertension with Intrauterine Growth Retardation
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2004  |   Pubmed ID: 14688210
• The Endothelin Receptor Antagonist Ameliorates the Hypertensive Phenotypes of Transgenic Hypertensive Mice with Renin-angiotensin Genes and Discloses Roles of Organ Specific Activation of Endothelin System in Transgenic Mice
  Life Sciences. Jan, 2004  |   Pubmed ID: 14687651
• Hypothalamic Orexin Neurons Regulate Arousal According to Energy Balance in Mice
  Neuron. Jun, 2003  |   Pubmed ID: 12797956
• Elimination of Pasteurella Pneumotropica from a Contaminated Mouse Colony by Oral Administration of Enrofloxacin
  Experimental Animals. Jul, 2002  |   Pubmed ID: 12221935
• Intraocular Pressure in Genetically Distinct Mice: an Update and Strain Survey
  BMC Genetics. 2001  |   Pubmed ID: 11532192
• Propagation of Rat Parvovirus in Thymic Lymphoma Cell Line C58(NT)d and Subsequent Appearance of a Resistant Cell Clone After Lytic Infection
  Journal of Virology. Apr, 2001  |   Pubmed ID: 11264385
• Targeted Expression of Baculovirus P35 Caspase Inhibitor in Oligodendrocytes Protects Mice Against Autoimmune-mediated Demyelination
  The EMBO Journal. Feb, 2000  |   Pubmed ID: 10654933