Gaetano Donofrio Department of Veterinary Science University of Parma Biography Publications Institution JoVE Articles Gaetano Donofrio has not added a biography. If you are Gaetano Donofrio and would like to personalize this page please email our Author Liaison for assistance. Publications Bovine Herpesvirus-4-Based Vector Delivering Peste Des Petits Ruminants Virus Hemagglutinin ORF Induces Both Neutralizing Antibodies and Cytotoxic T Cell Responses Frontiers in Immunology. 2018 | Pubmed ID: 29556236 Induction of Antihuman C-C Chemokine Receptor Type 5 Antibodies by a Bovine Herpesvirus Type-4 Based Vector Frontiers in Immunology. 2017 | Pubmed ID: 29118763 Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus Frontiers in Immunology. 2017 | Pubmed ID: 28878771 Assessment and Optimization of Theileria Parva Sporozoite Full-length P67 Antigen Expression in Mammalian Cells PLoS Neglected Tropical Diseases. Aug, 2017 | Pubmed ID: 28800590 Bovine Herpes Virus Type 4 Alters TNF-α and IL-8 Profiles and Impairs the Survival of Bovine Endometrial Epithelial Cells Reproductive Biology. May, 2017 | Pubmed ID: 28546031 Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice Frontiers in Immunology. 2017 | Pubmed ID: 28298912 Immunization of Bighorn Sheep Against Mannheimia Haemolytica with a Bovine Herpesvirus 1-vectored Vaccine Vaccine. Mar, 2017 | Pubmed ID: 28228321 Interleukin 8 Haplotypes Drive Divergent Responses in Uterine Endometrial Cells and Are Associated with Somatic Cell Score in Holstein-Friesian Cattle Veterinary Immunology and Immunopathology. Feb, 2017 | Pubmed ID: 28166928 IL21R Expressing CD14(+)CD16(+) Monocytes Expand in Multiple Myeloma Patients Leading to Increased Osteoclasts Haematologica. Apr, 2017 | Pubmed ID: 28057743 Nonviral Gene-delivery by Highly Fluorinated Gemini Bispyridinium Surfactant-based DNA Nanoparticles Journal of Colloid and Interface Science. Feb, 2017 | Pubmed ID: 27769002 BoHV-4-based Vector Delivering Ebola Virus Surface Glycoprotein Journal of Translational Medicine. Nov, 2016 | Pubmed ID: 27881138 In Vivo Monitoring of Lung Inflammation in CFTR-deficient Mice Journal of Translational Medicine. Jul, 2016 | Pubmed ID: 27468800 Virus-Mediated Metalloproteinase 1 Induction Revealed by Transcriptome Profiling of Bovine Herpesvirus 4-Infected Bovine Endometrial Stromal Cells Biology of Reproduction. Jul, 2016 | Pubmed ID: 27281703 A Chimeric Protein Comprising the Immunogenic Domains of Mannheimia Haemolytica Leukotoxin and Outer Membrane Protein PlpE Induces Antibodies Against Leukotoxin and PlpE Veterinary Immunology and Immunopathology. Jul, 2016 | Pubmed ID: 27269790 Dependence on Glutamine Uptake and Glutamine Addiction Characterize Myeloma Cells: a New Attractive Target Blood. Aug, 2016 | Pubmed ID: 27268090 Bovine Herpesvirus 4-based Vector Delivering a Hybrid Rat/human HER-2 Oncoantigen Efficiently Protects Mice from Autochthonous Her-2(+) Mammary Cancer Oncoimmunology. Mar, 2016 | Pubmed ID: 27141335 The Anti-tumoral Effect of Lenalidomide is Increased in Vivo by Hypoxia-inducible Factor (HIF)-1α Inhibition in Myeloma Cells Haematologica. Mar, 2016 | Pubmed ID: 26659917 BoHV-4 Immediate Early 1 Gene is a Dispensable Gene and Its Product is Not a Bone Marrow Stromal Cell Antigen 2 Counteracting Factor BMC Veterinary Research. Aug, 2015 | Pubmed ID: 26307352 In Vivo Imaging of the Lung Inflammatory Response to Pseudomonas Aeruginosa and Its Modulation by Azithromycin Journal of Translational Medicine. Aug, 2015 | Pubmed ID: 26239109 BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge PLoS Neglected Tropical Diseases. Jun, 2015 | Pubmed ID: 26086739 Cyclodextrin- and Calixarene-based Polycationic Amphiphiles As Gene Delivery Systems: a Structure-activity Relationship Study Organic & Biomolecular Chemistry. Feb, 2015 | Pubmed ID: 25474077 Azithromycin Inhibits Nuclear Factor-κB Activation During Lung Inflammation: an in Vivo Imaging Study Pharmacology Research & Perspectives. Oct, 2014 | Pubmed ID: 25505605 Nonviral Gene Delivery: Gemini Bispyridinium Surfactant-based DNA Nanoparticles The Journal of Physical Chemistry. B. Nov, 2014 | Pubmed ID: 25340646 Interferon Gamma-mediated BoHV-4 Replication Restriction in Bovine Endometrial Stromal Cells is Host IDO1 Gene Expression Independent and BoHV-4 IE2 Gene Expression Dependent Biology of Reproduction. Nov, 2014 | Pubmed ID: 25273529 Generation and Characterization of the First Immortalized Alpaca Cell Line Suitable for Diagnostic and Immunization Studies PloS One. 2014 | Pubmed ID: 25140515 Retinal Transduction Profiles by High-capacity Viral Vectors Gene Therapy. Oct, 2014 | Pubmed ID: 24989814 In Vivo Image Analysis of BoHV-4-based Vector in Mice PloS One. 2014 | Pubmed ID: 24752229 Enlightened Mannhemia Haemolytica Lung Inflammation in Bovinized Mice Veterinary Research. Jan, 2014 | Pubmed ID: 24460618 Aurora and IKK Kinases Cooperatively Interact to Protect Multiple Myeloma Cells from Apo2L/TRAIL Blood. Oct, 2013 | Pubmed ID: 23974204 Efficient Heterologous Antigen Gene Delivery and Expression by a Replication-attenuated BoHV-4-based Vaccine Vector Vaccine. Aug, 2013 | Pubmed ID: 23830977 Arginine Clustering on Calix[4]arene Macrocycles for Improved Cell Penetration and DNA Delivery Nature Communications. 2013 | Pubmed ID: 23591888 Bovine Endometrial Stromal Cells Support Tumor Necrosis Factor Alpha-induced Bovine Herpesvirus Type 4 Enhanced Replication Biology of Reproduction. May, 2013 | Pubmed ID: 23515672 Characterization of Caprine Herpesvirus 1 (CpHV1) Glycoprotein E and Glycoprotein I Ectodomains Expressed in Mammalian Cells Veterinary Microbiology. Jun, 2013 | Pubmed ID: 23490557 Bovine Herpesvirus 4 Glycoprotein B is Indispensable for Lytic Replication and Irreplaceable by VSVg BMC Veterinary Research. Jan, 2013 | Pubmed ID: 23302472 Clinical Protection of Goats Against CpHV-1 Induced Genital Disease with a BoHV-4-based Vector Expressing CpHV-1 GD PloS One. 2013 | Pubmed ID: 23300989 In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/luciferase Reporter Construct PloS One. 2012 | Pubmed ID: 22761878 Lower Rim Guanidinocalix[4]arenes: Macrocyclic Nonviral Vectors for Cell Transfection Bioconjugate Chemistry. May, 2012 | Pubmed ID: 22463059 Herpes Simplex Virus Type 1 Thymidine Kinase-armed Bovine Herpesvirus Type 4-based Vector Displays Enhanced Oncolytic Properties in Immunocompetent Orthotopic Syngenic Mouse and Rat Glioma Models Neuro-oncology. Mar, 2012 | Pubmed ID: 22228853 Immunization of Knock-out α/β Interferon Receptor Mice Against Lethal Bluetongue Infection with a BoHV-4-based Vector Expressing BTV-8 VP2 Antigen Vaccine. Apr, 2011 | Pubmed ID: 21320537 Swine Adipose Stromal Cells Loaded with Recombinant Bovine Herpesvirus 4 Virions Expressing a Foreign Antigen Induce Potent Humoral Immune Responses in Pigs Vaccine. Jan, 2011 | Pubmed ID: 21115049 Bovine Herpesvirus 4 Immediate Early 2 (Rta) Gene is an Essential Gene and is Duplicated in Bovine Herpesvirus 4 Isolate U Veterinary Microbiology. Mar, 2011 | Pubmed ID: 21035279 Bovine Herpesvirus 4 Based Vector As a Potential Oncolytic-virus for Treatment of Glioma Virology Journal. Nov, 2010 | Pubmed ID: 21047419 Virally and Physically Transgenized Equine Adipose-derived Stromal Cells As a Cargo for Paracrine Secreted Factors BMC Cell Biology. Sep, 2010 | Pubmed ID: 20863390 Integration of Bovine Herpesvirus 4 Genome into Cultured Persistently Infected Host Cell Genome Virology Journal. Sep, 2010 | Pubmed ID: 20854697 The Chemokine IL8 is Up-regulated in Bovine Endometrial Stromal Cells by the BoHV-4 IE2 Gene Product, ORF50/Rta: a Step Ahead Toward a Mechanism for BoHV-4 Induced Endometritis Biology of Reproduction. Dec, 2010 | Pubmed ID: 20720165 Isolation and Characterization of a Strain of Lichtheimia Corymbifera (ex Absidia Corymbifera) from a Case of Bovine Abortion Reproductive Biology and Endocrinology : RB&E. Nov, 2009 | Pubmed ID: 19948023 Cellular Targeting of Engineered Heterologous Antigens is a Determinant Factor for Bovine Herpesvirus 4-based Vaccine Vector Development Clinical and Vaccine Immunology : CVI. Nov, 2009 | Pubmed ID: 19793901 Isolation and Characterization of Bovine Herpesvirus 4 (BoHV-4) from a Cow Affected by Post Partum Metritis and Cloning of the Genome As a Bacterial Artificial Chromosome Reproductive Biology and Endocrinology : RB&E. Aug, 2009 | Pubmed ID: 19691825 Defining Postpartum Uterine Disease and the Mechanisms of Infection and Immunity in the Female Reproductive Tract in Cattle Biology of Reproduction. Dec, 2009 | Pubmed ID: 19439727 Bovine Endometrial Stromal Cells Display Osteogenic Properties Reproductive Biology and Endocrinology : RB&E. Dec, 2008 | Pubmed ID: 19087287 Double Immunization Strategy with a BoHV-4-vectorialized Secreted Chimeric Peptide BVDV-E2/BoHV-1-gD Vaccine. Nov, 2008 | Pubmed ID: 18812200 Macrocyclic Nonviral Vectors: High Cell Transfection Efficiency and Low Toxicity in a Lower Rim Guanidinium Calix[4]arene Organic Letters. Sep, 2008 | Pubmed ID: 18722463 Thermodynamics and Biological Properties of the Aqueous Solutions of New Glucocationic Surfactants The Journal of Physical Chemistry. B. Aug, 2008 | Pubmed ID: 18616333 Bacterial Infection of Endometrial Stromal Cells Influences Bovine Herpesvirus 4 Immediate Early Gene Activation: a New Insight into Bacterial and Viral Interaction for Uterine Disease Reproduction (Cambridge, England). Sep, 2008 | Pubmed ID: 18577555 Transduction of the Rat Brain by Bovine Herpesvirus 4 Genetic Vaccines and Therapy. Feb, 2008 | Pubmed ID: 18267037 Assessment of Bovine Herpesvirus 4 Based Vector in Chicken Journal of Virological Methods. Mar, 2008 | Pubmed ID: 18243344 Establishment of a Bovine Herpesvirus 4 Based Vector Expressing a Secreted Form of the Bovine Viral Diarrhoea Virus Structural Glycoprotein E2 for Immunization Purposes BMC Biotechnology. Oct, 2007 | Pubmed ID: 17945009 The New Tumor-suppressor Gene Inhibitor of Growth Family Member 4 (ING4) Regulates the Production of Proangiogenic Molecules by Myeloma Cells and Suppresses Hypoxia-inducible Factor-1 Alpha (HIF-1alpha) Activity: Involvement in Myeloma-induced Angiogenesis Blood. Dec, 2007 | Pubmed ID: 17848618 Production of Wnt Inhibitors by Myeloma Cells: Potential Effects on Canonical Wnt Pathway in the Bone Microenvironment Cancer Research. Aug, 2007 | Pubmed ID: 17702698 Bovine Herpesvirus 4 is Tropic for Bovine Endometrial Cells and Modulates Endocrine Function Reproduction (Cambridge, England). Jul, 2007 | Pubmed ID: 17641100 First Serbian Isolates of Bovine Herpesvirus 4 (BoHV-4) from a Herd with a History of Postpartum Metritis The New Microbiologica. Jan, 2007 | Pubmed ID: 17319601 Generation of a Transposon Insertion Mutant Library for Bovine Herpesvirus 4 Cloned As a Bacterial Artificial Chromosome by in Vitro MuA Based DNA Transposition System Journal of Virological Methods. Apr, 2007 | Pubmed ID: 17182112 DNA Condensation and Cell Transfection Properties of Guanidinium Calixarenes: Dependence on Macrocycle Lipophilicity, Size, and Conformation Journal of the American Chemical Society. Nov, 2006 | Pubmed ID: 17090036 Association Between Coxiella Burnetii Seropositivity and Abortion in Dairy Cattle of Northern Italy The New Microbiologica. Jul, 2006 | Pubmed ID: 17058789 Recombinant Bovine Herpesvirus 4 (BoHV-4) Expressing Glycoprotein D of BoHV-1 is Immunogenic and Elicits Serum-neutralizing Antibodies Against BoHV-1 in a Rabbit Model Clinical and Vaccine Immunology : CVI. Nov, 2006 | Pubmed ID: 16928886 Expression of Bovine Viral Diarrhea Virus Glycoprotein E2 As a Soluble Secreted Form in a Mammalian Cell Line Clinical and Vaccine Immunology : CVI. Jun, 2006 | Pubmed ID: 16760329 Bovine Herpesvirus 4 Based Vector Interaction with Liver Cells in Vitro and in Vivo Journal of Virological Methods. Sep, 2006 | Pubmed ID: 16712963 Outcome of Bovine Herpesvirus 4 Infection Following Direct Viral Injection in the Lateral Ventricle of the Mouse Brain Microbes and Infection. Mar, 2006 | Pubmed ID: 16503181 Potential Secondary Pathogenic Role for Bovine Herpesvirus 4 Journal of Clinical Microbiology. Jul, 2005 | Pubmed ID: 16000468 Paracrine Inhibition of Prion Propagation by Anti-PrP Single-chain Fv Miniantibodies Journal of Virology. Jul, 2005 | Pubmed ID: 15956578 Biologically Active Bisquaternary Ammonium Chlorides: Physico-chemical Properties of Long Chain Amphiphiles and Their Evaluation As Non-viral Vectors for Gene Delivery Biochimica Et Biophysica Acta. Mar, 2005 | Pubmed ID: 15725392 Bovine Herpesvirus 4 Infects Differentiated Neuronal Cells in Culture and Establish Persistent Infection Upon Selection Journal of Neurovirology. Apr, 2004 | Pubmed ID: 15204931 Activation of Bovine Herpesvirus 4 Lytic Replication in a Non-permissive Cell Line by Overexpression of BoHV-4 Immediate Early (IE) 2 Gene Journal of Virological Methods. Mar, 2004 | Pubmed ID: 14738989 Potential of Bovine Herpesvirus 4 As a Gene Delivery Vector Journal of Virological Methods. Mar, 2002 | Pubmed ID: 11849683 Multimodal 접근을 이미징 Bleomycin 유도 폐 섬유 증 생쥐에서의 경도 평가 대 한 마이크로-CT와 형광 분자 단층에 따라 Francesca Ruscitti1, Francesca Ravanetti2, Gaetano Donofrio2, Yanto Ridwan3, Paula van Heijningen3, Jeroen Essers4, Gino Villetti1, Antonio Cacchioli2, Wim Vos5, Franco Fabio Stellari1 1Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 2Department of Veterinary Science, University of Parma, 3Department of Molecular Genetics, Erasmus MC, 4Department of Molecular Genetics, Vascular Surgery, Radiation Oncology, Erasmus MC, 5Fluidda NV JoVE 56443 Immunology and Infection IL-8 transiently Transgenized 마우스 모델 Gabriella Bergamini*1, Fabio Stellari*2, Angela Sandri*3, Maria M. Lleo3, Gaetano Donofrio4, Francesca Ruscitti5,2, Federico Boschi6, Andrea Sbarbati7, Gino Villetti2, Paola Melotti8, Claudio Sorio1 1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona, 2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 3Department of Diagnostic and Public Health, Microbiology Division, University of Verona, 4Dipartimento di Scienze Medico-Veterinarie, University of Parma, 5Department of Biomedical Biotechnological and Translational Sciences, University of Parma, 6Department of Computer Science, University of Verona, 7Department of Neurological, Biomedical and Movement Sciences, University of Verona, 8Cystic Fibrosis Regional Center (CFC), AOUI Verona JoVE 55499 Immunology and Infection
Multimodal 접근을 이미징 Bleomycin 유도 폐 섬유 증 생쥐에서의 경도 평가 대 한 마이크로-CT와 형광 분자 단층에 따라 Francesca Ruscitti1, Francesca Ravanetti2, Gaetano Donofrio2, Yanto Ridwan3, Paula van Heijningen3, Jeroen Essers4, Gino Villetti1, Antonio Cacchioli2, Wim Vos5, Franco Fabio Stellari1 1Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 2Department of Veterinary Science, University of Parma, 3Department of Molecular Genetics, Erasmus MC, 4Department of Molecular Genetics, Vascular Surgery, Radiation Oncology, Erasmus MC, 5Fluidda NV JoVE 56443 Immunology and Infection
IL-8 transiently Transgenized 마우스 모델 Gabriella Bergamini*1, Fabio Stellari*2, Angela Sandri*3, Maria M. Lleo3, Gaetano Donofrio4, Francesca Ruscitti5,2, Federico Boschi6, Andrea Sbarbati7, Gino Villetti2, Paola Melotti8, Claudio Sorio1 1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona, 2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 3Department of Diagnostic and Public Health, Microbiology Division, University of Verona, 4Dipartimento di Scienze Medico-Veterinarie, University of Parma, 5Department of Biomedical Biotechnological and Translational Sciences, University of Parma, 6Department of Computer Science, University of Verona, 7Department of Neurological, Biomedical and Movement Sciences, University of Verona, 8Cystic Fibrosis Regional Center (CFC), AOUI Verona JoVE 55499 Immunology and Infection
