Gareth J.S. Jenkins In vitro Toxicology Group Swansea University Medical School Biography Publications Institution JoVE Articles Gareth J.S. Jenkins has not added a biography. If you are Gareth J.S. Jenkins and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of Passive-dosed and Solvent Spiked Exposures of Pro-carcinogen, Benzo[a]pyrene, to Human Lymphoblastoid Cell Line, MCL-5 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Jun, 2020 | Pubmed ID: 32497684 Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety Chemical Research in Toxicology. May, 2020 | Pubmed ID: 32307980 Reprint Of: A Three-dimensional in Vitro HepG2 Cells Liver Spheroid Model for Genotoxicity Studies Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Oct, 2018 | Pubmed ID: 30173862 A Three-dimensional in Vitro HepG2 Cells Liver Spheroid Model for Genotoxicity Studies Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Jan, 2018 | Pubmed ID: 29307375 A Novel, Integrated in Vitro Carcinogenicity Test to Identify Genotoxic and Non-genotoxic Carcinogens Using Human Lymphoblastoid Cells Archives of Toxicology. Feb, 2018 | Pubmed ID: 29110037 The Role of Intracellular Trafficking of CdSe/ZnS QDs on Their Consequent Toxicity Profile Journal of Nanobiotechnology. Jun, 2017 | Pubmed ID: 28619032 Critical Review of the Current and Future Challenges Associated with Advanced in Vitro Systems Towards the Study of Nanoparticle (secondary) Genotoxicity Mutagenesis. 01, 2017 | Pubmed ID: 27815329 A Comparison of the Genotoxicity of Benzo[a]pyrene in Four Cell Lines with Differing Metabolic Capacity Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Sep, 2016 | Pubmed ID: 27637481 Genetic Toxicity Assessment of Engineered Nanoparticles Using a 3D in Vitro Skin Model (EpiDerm™) Particle and Fibre Toxicology. 09, 2016 | Pubmed ID: 27613375 Genotoxic Thresholds, DNA Repair, and Susceptibility in Human Populations Toxicology. Dec, 2010 | Pubmed ID: 19932733 The Bile Acid Deoxycholic Acid Has a Non-linear Dose Response for DNA Damage and Possibly NF-kappaB Activation in Oesophageal Cells, with a Mechanism of Action Involving ROS Mutagenesis. Sep, 2008 | Pubmed ID: 18515815 Immunohistochemical Study of Nuclear Factor-kappaB Activity and Interleukin-8 Abundance in Oesophageal Adenocarcinoma; a Useful Strategy for Monitoring These Biomarkers Journal of Clinical Pathology. Nov, 2007 | Pubmed ID: 17220207 Deoxycholic Acid at Neutral and Acid PH, is Genotoxic to Oesophageal Cells Through the Induction of ROS: The Potential Role of Anti-oxidants in Barrett's Oesophagus Carcinogenesis. Jan, 2007 | Pubmed ID: 16905748 The Restriction Site Mutation (RSM) Method: Clinical Applications Mutagenesis. Jan, 2004 | Pubmed ID: 14681308 The Bile Acid Deoxycholic Acid (DCA) at Neutral PH Activates NF-kappaB and Induces IL-8 Expression in Oesophageal Cells in Vitro Carcinogenesis. Mar, 2004 | Pubmed ID: 14656946 Early P53 Mutations in Nondysplastic Barrett's Tissue Detected by the Restriction Site Mutation (RSM) Methodology British Journal of Cancer. Apr, 2003 | Pubmed ID: 12698195 Molecular Analysis of the Chemoprotective Effects of Topical Sunscreen and Vitamin C in Preventing UV-induced and Reactive Oxygen Species-induced DNA Damage, Respectively, Using the PCR Inhibition Methodology Anticancer Research. Nov-Dec, 2002 | Pubmed ID: 12553007 Genetic Pathways Involved in the Progression of Barrett's Metaplasia to Adenocarcinoma The British Journal of Surgery. Jul, 2002 | Pubmed ID: 12081731 Restriction Enzymes in the Analysis of Genetic Alterations Responsible for Cancer Progression The British Journal of Surgery. Jan, 2002 | Pubmed ID: 11851658 The Detection of Mutations Induced in Vitro in the Human P53 Gene by Hydrogen Peroxide with the Restriction Site Mutation (RSM) Assay Mutation Research. Nov, 2001 | Pubmed ID: 11673079 PCR-based Methodology for the Determination of the Photoprotection Afforded by Sunscreen Application BioTechniques. Dec, 2000 | Pubmed ID: 11126135 Restriction Site Mutation (RSM) Analysis of 2-acetylaminofluorene (2-AAF)-induced Mouse Liver Mutations and Comparison with the Measurement of in Vivo Micronucleus Induction in the Bone Marrows of (2-AAF)-treated Mice Teratogenesis, Carcinogenesis, and Mutagenesis. 2000 | Pubmed ID: 10820421 Inverse Restriction Site Mutation (iRSM) Analysis. Mutation Detection Involving the Formation of Restriction Enzyme Sites in Target Genes Mutagenesis. Jan, 1999 | Pubmed ID: 10474819 The Restriction Site Mutation Assay: a Review of the Methodology Development and the Current Status of the Technique Mutagenesis. Sep, 1999 | Pubmed ID: 10473646 A Study of ENU-induced Mutagenesis in the Mouse Using the Restriction Site Mutation (RSM) Assay Teratogenesis, Carcinogenesis, and Mutagenesis. 1999 | Pubmed ID: 10406892 Mutation Analysis Using the Restriction Site Mutation (RSM) Assay Mutation Research. Sep, 1998 | Pubmed ID: 9748583 Investigating FlowSight® Imaging Flow Cytometry As a Platform to Assess Chemically Induced Micronuclei Using Human Lymphoblastoid Cells in Vitro Mutagenesis. | Pubmed ID: 30204902 Avancerede 3D-levermodeller til in vitro genotoksicitetstest efter langvarig nanomaterialeeksponering Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioengineering
Avancerede 3D-levermodeller til in vitro genotoksicitetstest efter langvarig nanomaterialeeksponering Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioengineering