Geoff H. Werstuck Department of Biochemistry and Biomedical Sciences McMaster University Biography Publications Institution JoVE Articles Geoff H. Werstuck has not added a biography. If you are Geoff H. Werstuck and would like to personalize this page please email our Author Liaison for assistance. Publications The Development and Progression of Atherosclerosis: Evidence Supporting a Role for Endoplasmic Reticulum (ER) Stress Signaling Cardiovascular & Hematological Disorders Drug Targets. Aug, 2013 | Pubmed ID: 23988003 Detection and Quantification of Endoplasmic Reticulum Stress in Living Cells Using the Fluorescent Compound, Thioflavin T Biochimica Et Biophysica Acta. Oct, 2013 | Pubmed ID: 23747341 Leptin Promotes Osteoblast Differentiation and Mineralization of Primary Cultures of Vascular Smooth Muscle Cells by Inhibiting Glycogen Synthase Kinase (GSK)-3β Biochemical and Biophysical Research Communications. Sep, 2012 | Pubmed ID: 22906741 The Role of Glucosamine-induced ER Stress in Diabetic Atherogenesis Experimental Diabetes Research. 2012 | Pubmed ID: 22474416 Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E-deficient Mouse Models of Accelerated Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2012 | Pubmed ID: 21998135 Metabolic Syndrome and Acute Hyperglycemia Are Associated with Endoplasmic Reticulum Stress in Human Mononuclear Cells Obesity (Silver Spring, Md.). Apr, 2012 | Pubmed ID: 21633399 Glucosamine-supplementation Promotes Endoplasmic Reticulum Stress, Hepatic Steatosis and Accelerated Atherogenesis in ApoE-/- Mice Atherosclerosis. Nov, 2011 | Pubmed ID: 21855875 Diabetes, Hyperglycemia and Accelerated Atherosclerosis: Evidence Supporting a Role for Endoplasmic Reticulum (ER) Stress Signaling Cardiovascular & Hematological Disorders Drug Targets. Jun, 2010 | Pubmed ID: 20350283 Hexosamine Biosynthesis Pathway Flux Promotes Endoplasmic Reticulum Stress, Lipid Accumulation, and Inflammatory Gene Expression in Hepatic Cells American Journal of Physiology. Endocrinology and Metabolism. Mar, 2010 | Pubmed ID: 19952345 Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model Antioxidants & Redox Signaling. Sep, 2009 | Pubmed ID: 19548776 Valproate Attenuates Accelerated Atherosclerosis in Hyperglycemic ApoE-deficient Mice: Evidence in Support of a Role for Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3 in Lesion Development and Hepatic Steatosis The American Journal of Pathology. Jan, 2009 | Pubmed ID: 19095952 Hyperhomocysteinemia Induced by Methionine Supplementation Does Not Independently Cause Atherosclerosis in C57BL/6J Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2008 | Pubmed ID: 18364397 Diabetes and Cardiovascular Disease: Explaining the Relationship Reviews in Cardiovascular Medicine. 2007 | Pubmed ID: 17938614 Endoplasmic Reticulum Stress Causes the Activation of Sterol Regulatory Element Binding Protein-2 The International Journal of Biochemistry & Cell Biology. 2007 | Pubmed ID: 17604677 Induction of GRP78 by Valproic Acid is Dependent Upon Histone Deacetylase Inhibition Bioorganic & Medicinal Chemistry Letters. Aug, 2007 | Pubmed ID: 17566732 Mechanisms Linking Diabetes Mellitus to the Development of Atherosclerosis: a Role for Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3 Canadian Journal of Physiology and Pharmacology. Jan, 2006 | Pubmed ID: 16845889 Glucosamine-induced Endoplasmic Reticulum Dysfunction is Associated with Accelerated Atherosclerosis in a Hyperglycemic Mouse Model Diabetes. Jan, 2006 | Pubmed ID: 16380481 Valproate Protects Cells from ER Stress-induced Lipid Accumulation and Apoptosis by Inhibiting Glycogen Synthase Kinase-3 Journal of Cell Science. Jan, 2005 | Pubmed ID: 15585578 Examining the Correlations Between GSK-3 Inhibitory Properties and Anti-convulsant Efficacy of Valproate and Valproate-related Compounds Bioorganic & Medicinal Chemistry Letters. Nov, 2004 | Pubmed ID: 15482904 Association of Multiple Cellular Stress Pathways with Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-deficient Mice Circulation. Jul, 2004 | Pubmed ID: 15210586 Hyperhomocysteinemia and Its Role in the Development of Atherosclerosis Clinical Biochemistry. Sep, 2003 | Pubmed ID: 12951169 TDAG51 is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Cevelopment of Atherosclerosis in Hyperhomocysteinemia The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12738777 Overexpression of the 78-kDa Glucose-regulated Protein/immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12621026 Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton. Potential Role in Thrombin-mediated Platelet Adhesion The Journal of Biological Chemistry. Dec, 2002 | Pubmed ID: 12370193 マウス大動脈洞におけるアテローム性動脈硬化症の病変の定量分析とキャラクタリゼーション Daniel E. Venegas-Pino1, Nicole Banko1, Mohammed I. Khan2, Yuanyuan Shi2, Geoff H. Werstuck1,2 1Department of Biochemistry and Biomedical Sciences, McMaster University, 2Thrombosis and Atherosclerosis Research Institute, McMaster University Medicine
マウス大動脈洞におけるアテローム性動脈硬化症の病変の定量分析とキャラクタリゼーション Daniel E. Venegas-Pino1, Nicole Banko1, Mohammed I. Khan2, Yuanyuan Shi2, Geoff H. Werstuck1,2 1Department of Biochemistry and Biomedical Sciences, McMaster University, 2Thrombosis and Atherosclerosis Research Institute, McMaster University Medicine