Geoffrey Chupp Pulmonary, Critical Care and Sleep Medicine Yale University School of Medicine Biography Publications Institution JoVE Articles Geoffrey Chupp has not added a biography. If you are Geoffrey Chupp and would like to personalize this page please email our Author Liaison for assistance. Publications Phenotypes and Endotypes of Adult Asthma: Moving Toward Precision Medicine The Journal of Allergy and Clinical Immunology. Jul, 2019 | Pubmed ID: 31277742 Rapid Onset of Effect of Benralizumab on Morning Peak Expiratory Flow in Severe, Uncontrolled Asthma Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. May, 2019 | Pubmed ID: 30802500 Pulmonary Artery Pseudoaneurysm Causing Massive Hemoptysis in Hyperimmunoglobulin E Syndrome: a Case Report BMC Pulmonary Medicine. Feb, 2019 | Pubmed ID: 30736787 Bronchial Thermoplasty Clinics in Chest Medicine. Mar, 2019 | Pubmed ID: 30691712 Building an Informed Consent Tool Starting with the Patient: The Patient-Centered Virtual Multimedia Interactive Informed Consent (VIC) AMIA ... Annual Symposium Proceedings. AMIA Symposium. 2017 | Pubmed ID: 29854101 Characterisation of Asthma Subgroups Associated with Circulating YKL-40 Levels The European Respiratory Journal. 10, 2017 | Pubmed ID: 29025889 Long-term Outcomes of Bronchial Thermoplasty in Subjects with Severe Asthma: a Comparison of 3-year Follow-up Results from Two Prospective Multicentre Studies The European Respiratory Journal. 08, 2017 | Pubmed ID: 28860266 Reappraisal of the Clinical Effect of Mepolizumab - Authors' Reply The Lancet. Respiratory Medicine. 06, 2017 | Pubmed ID: 28664853 Efficacy of Mepolizumab Add-on Therapy on Health-related Quality of Life and Markers of Asthma Control in Severe Eosinophilic Asthma (MUSCA): a Randomised, Double-blind, Placebo-controlled, Parallel-group, Multicentre, Phase 3b Trial The Lancet. Respiratory Medicine. 05, 2017 | Pubmed ID: 28395936 Multiparameter Single Cell Profiling of Airway Inflammatory Cells Cytometry. Part B, Clinical Cytometry. 01, 2017 | Pubmed ID: 27807928 Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma Annals of the American Thoracic Society. Mar, 2016 | Pubmed ID: 27027964 Asthma Characteristics and Biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) Longitudinal Profiling Study Respiratory Research. Nov, 2015 | Pubmed ID: 26576744 Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma American Journal of Respiratory and Critical Care Medicine. May, 2015 | Pubmed ID: 25763605 Chitinase 3-like-1 Regulates Both Visceral Fat Accumulation and Asthma-like Th2 Inflammation American Journal of Respiratory and Critical Care Medicine. Apr, 2015 | Pubmed ID: 25629580 Genetic Variation in Chitinase 3-like 1 (CHI3L1) Contributes to Asthma Severity and Airway Expression of YKL-40 The Journal of Allergy and Clinical Immunology. Jul, 2015 | Pubmed ID: 25592985 IL-6 Receptor α Defines Effector Memory CD8+ T Cells Producing Th2 Cytokines and Expanding in Asthma American Journal of Respiratory and Critical Care Medicine. Dec, 2014 | Pubmed ID: 25390970 Role of Growth Arrest-specific Gene 6 in the Development of Fungal Allergic Airway Disease in Mice American Journal of Respiratory Cell and Molecular Biology. Nov, 2014 | Pubmed ID: 24810144 Improvement in Asthma Control and Inflammation in Children Undergoing Adenotonsillectomy Pediatric Research. Mar, 2014 | Pubmed ID: 24452590 Segmental Allergen Challenge Enhances Chitinase Activity and Levels of CCL18 in Mild Atopic Asthma Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Feb, 2013 | Pubmed ID: 23331560 Chitinase-like Protein Brp-39/YKL-40 Modulates the Renal Response to Ischemic Injury and Predicts Delayed Allograft Function Journal of the American Society of Nephrology : JASN. Feb, 2013 | Pubmed ID: 23291472 Targeting ST2L Potentiates CpG-mediated Therapeutic Effects in a Chronic Fungal Asthma Model The American Journal of Pathology. Jul, 2011 | Pubmed ID: 21640974 Role of Breast Regression Protein-39 in the Pathogenesis of Cigarette Smoke-induced Inflammation and Emphysema American Journal of Respiratory Cell and Molecular Biology. Jun, 2011 | Pubmed ID: 20656949 The Chitinase and Chitinase-like Proteins: a Review of Genetic and Functional Studies in Asthma and Immune-mediated Diseases Current Opinion in Allergy and Clinical Immunology. Oct, 2009 | Pubmed ID: 19644363 Novel Biomarkers in Asthma: Chemokines and Chitinase-like Proteins Current Opinion in Allergy and Clinical Immunology. Feb, 2009 | Pubmed ID: 19532094 Role of Breast Regression Protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced Tissue Responses and Apoptosis The Journal of Experimental Medicine. May, 2009 | Pubmed ID: 19414556 A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma The New England Journal of Medicine. Nov, 2007 | Pubmed ID: 18003958 IL-18 is Induced and IL-18 Receptor Alpha Plays a Critical Role in the Pathogenesis of Cigarette Smoke-induced Pulmonary Emphysema and Inflammation Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007 | Pubmed ID: 17237446 Hyperoxia Causes Angiopoietin 2-mediated Acute Lung Injury and Necrotic Cell Death Nature Medicine. Nov, 2006 | Pubmed ID: 17086189 Transgenic Modeling of Transforming Growth Factor-beta(1): Role of Apoptosis in Fibrosis and Alveolar Remodeling Proceedings of the American Thoracic Society. Jul, 2006 | Pubmed ID: 16799085 Asthma: Mechanisms of Disease Persistence and Progression Annual Review of Immunology. 2004 | Pubmed ID: 15032597 Reactive Oxygen Species and Extracellular Signal-regulated Kinase 1/2 Mitogen-activated Protein Kinase Mediate Hyperoxia-induced Cell Death in Lung Epithelium American Journal of Respiratory Cell and Molecular Biology. Mar, 2003 | Pubmed ID: 12594056 IL-13 Stimulates Vascular Endothelial Cell Growth Factor and Protects Against Hyperoxic Acute Lung Injury The Journal of Clinical Investigation. Sep, 2000 | Pubmed ID: 10995789 Airway Remodeling in Asthma The Journal of Clinical Investigation. Oct, 1999 | Pubmed ID: 10525034 Tissue and T Cell Distribution of Precursor and Mature IL-16 Journal of Immunology (Baltimore, Md. : 1950). Sep, 1998 | Pubmed ID: 9743378 Measurement of Chitinase Activity in Biological Samples Alyssa K. Amick1, Qing Liu1, Samir Gautam1, Geoffrey Chupp1, Charles S. Dela Cruz*1, Lokesh Sharma*1 1Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine JoVE 60159 Immunology and Infection
Measurement of Chitinase Activity in Biological Samples Alyssa K. Amick1, Qing Liu1, Samir Gautam1, Geoffrey Chupp1, Charles S. Dela Cruz*1, Lokesh Sharma*1 1Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine JoVE 60159 Immunology and Infection