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Articles by George A. Khoury in JoVE
Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules James Smadbeck1, Meghan B. Peterson1, George A. Khoury1, Martin S. Taylor1, Christodoulos A. Floudas1 1Department of Chemical and Biological Engineering, Princeton University We developed computational de novo protein design methods capable of tackling several important areas of protein design. To disseminate these methods we present Protein WISDOM, an online tool for protein design (http://www.proteinwisdom.org). Starting from a structural template, design of monomeric proteins for increased stability and complexes for increased binding affinity can be performed.