Gil Atzmon Department of Medicine Albert Einstein College of Medicine Biography Publications Institution JoVE Articles Gil Atzmon has not added a biography. If you are Gil Atzmon and would like to personalize this page please email our Author Liaison for assistance. Publications Personality, Self-rated Health, and Cognition in Centenarians: Do Personality and Self-rated Health Relate to Cognitive Function in Advanced Age? Aging. Mar, 2013 | Pubmed ID: 23524310 Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc(1638N/+) Female Mice Cancer Prevention Research (Philadelphia, Pa.). Mar, 2013 | Pubmed ID: 23466815 Discovery of Novel Non-synonymous SNP Variants in 988 Candidate Genes from 6 Centenarians by Target Capture and Next-generation Sequencing Mechanisms of Ageing and Development. Feb, 2013 | Pubmed ID: 23376243 Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-enzyme-linked Immunosorbent Assay (ELISA) The Journal of Clinical Endocrinology and Metabolism. Jan, 2013 | Pubmed ID: 23162096 Gene Size Matters PloS One. 2012 | Pubmed ID: 23152854 Epigenetic Genome-wide Association Methylation in Aging and Longevity Epigenomics. Oct, 2012 | Pubmed ID: 23130832 North African Jewish and Non-Jewish Populations Form Distinctive, Orthogonal Clusters Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22869716 Comprehensive MicroRNA Profiling in B-cells of Human Centenarians by Massively Parallel Sequencing BMC Genomics. 2012 | Pubmed ID: 22846614 Positive Attitude Towards Life and Emotional Expression As Personality Phenotypes for Centenarians Aging. May, 2012 | Pubmed ID: 22626632 Distinguishing Between Longevity and Buffered-deleterious Genotypes for Exceptional Human Longevity: the Case of the MTP Gene The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Nov, 2012 | Pubmed ID: 22496539 Family History of Exceptional Longevity is Associated with Lower Serum Uric Acid Levels in Ashkenazi Jews Journal of the American Geriatrics Society. Apr, 2012 | Pubmed ID: 22429185 A Genome-wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci PLoS Genetics. 2012 | Pubmed ID: 22412388 Human Longevity and Common Variations in the LMNA Gene: a Meta-analysis Aging Cell. Jun, 2012 | Pubmed ID: 22340368 Evidence Against a Role for Rare ADAM10 Mutations in Sporadic Alzheimer Disease Neurobiology of Aging. Feb, 2012 | Pubmed ID: 20381196 Exceptional Longevity is Associated with Decreased Reproduction Aging. Dec, 2011 | Pubmed ID: 22199025 Lifestyle Factors of People with Exceptional Longevity Journal of the American Geriatrics Society. Aug, 2011 | Pubmed ID: 21812767 A Genome-wide Association Study of Aging Neurobiology of Aging. Nov, 2011 | Pubmed ID: 21782286 The History of African Gene Flow into Southern Europeans, Levantines, and Jews PLoS Genetics. Apr, 2011 | Pubmed ID: 21533020 Genetic Studies Reveal the Role of the Endocrine and Metabolic Systems in Aging The Journal of Clinical Endocrinology and Metabolism. Oct, 2010 | Pubmed ID: 20926537 Acute Humanin Therapy Attenuates Myocardial Ischemia and Reperfusion Injury in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2010 | Pubmed ID: 20651283 Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry American Journal of Human Genetics. Jun, 2010 | Pubmed ID: 20560205 Cholesteryl Ester Transfer Protein (CETP) Genotype and Reduced CETP Levels Associated with Decreased Prevalence of Hypertension Mayo Clinic Proceedings. Mayo Clinic. Jun, 2010 | Pubmed ID: 20511482 Aging Per Se Increases the Susceptibility to Free Fatty Acid-induced Insulin Resistance The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Aug, 2010 | Pubmed ID: 20504893 Tissue-specific Dysregulation of DNA Methylation in Aging Aging Cell. Aug, 2010 | Pubmed ID: 20497131 Gene-gene Interactions Lead to Higher Risk for Development of Type 2 Diabetes in an Ashkenazi Jewish Population PloS One. 2010 | Pubmed ID: 20361036 Evolution in Health and Medicine Sackler Colloquium: Genetic Variation in Human Telomerase is Associated with Telomere Length in Ashkenazi Centenarians Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19915151 RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. Elegans PloS One. 2009 | Pubmed ID: 20011587 Genetic Predisposition to Elevated Serum Thyrotropin is Associated with Exceptional Longevity The Journal of Clinical Endocrinology and Metabolism. Dec, 2009 | Pubmed ID: 19837933 Humanin: a Novel Central Regulator of Peripheral Insulin Action PloS One. 2009 | Pubmed ID: 19623253 Association of Common Genetic Variation in the Insulin/IGF1 Signaling Pathway with Human Longevity Aging Cell. Aug, 2009 | Pubmed ID: 19489743 Inflammation and Stress-related Candidate Genes, Plasma Interleukin-6 Levels, and Longevity in Older Adults Experimental Gerontology. May, 2009 | Pubmed ID: 19249341 Extreme Longevity is Associated with Increased Serum Thyrotropin The Journal of Clinical Endocrinology and Metabolism. Apr, 2009 | Pubmed ID: 19158193 Ashkenazi Jewish Centenarians Do Not Demonstrate Enrichment in Mitochondrial Haplogroup J PloS One. 2008 | Pubmed ID: 18923645 Enhanced Activation of a "nutrient-sensing" Pathway with Age Contributes to Insulin Resistance FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2008 | Pubmed ID: 18566293 Adiponectin Levels and Genotype: a Potential Regulator of Life Span in Humans The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. May, 2008 | Pubmed ID: 18511746 QTLs Detected in a Multigenerational Resource Chicken Population The Journal of Heredity. Sep-Oct, 2008 | Pubmed ID: 18492652 Visceral Adipose Tissue Modulates Mammalian Longevity Aging Cell. Jun, 2008 | Pubmed ID: 18363902 Functionally Significant Insulin-like Growth Factor I Receptor Mutations in Centenarians Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18316725 Accretion of Visceral Fat and Hepatic Insulin Resistance in Pregnant Rats American Journal of Physiology. Endocrinology and Metabolism. Feb, 2008 | Pubmed ID: 18073320 Buffering Mechanisms in Aging: a Systems Approach Toward Uncovering the Genetic Component of Aging PLoS Computational Biology. Aug, 2007 | Pubmed ID: 17784782 Aging-related Occurrence in Ashkenazi Jews of Leukocyte Heteroplasmic MtDNA Mutation Adjacent to Replication Origin Frequently Remodeled in Italian Centenarians Mitochondrion. Jul, 2007 | Pubmed ID: 17452024 Resistance to Leptin Action is the Major Determinant of Hepatic Triglyceride Accumulation in Vivo FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2007 | Pubmed ID: 17099068 Serum Heat Shock Protein 70 Level As a Biomarker of Exceptional Longevity Mechanisms of Ageing and Development. Nov, 2006 | Pubmed ID: 17027907 Central and Opposing Effects of IGF-I and IGF-binding Protein-3 on Systemic Insulin Action Diabetes. Oct, 2006 | Pubmed ID: 17003344 Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans PLoS Biology. Apr, 2006 | Pubmed ID: 16602826 Central Resistance to the Inhibitory Effects of Leptin on Stimulated Insulin Secretion with Aging Neurobiology of Aging. Sep, 2006 | Pubmed ID: 16122839 Differential Responses of Visceral and Subcutaneous Fat Depots to Nutrients Diabetes. Mar, 2005 | Pubmed ID: 15734842 Association Between a Functional Variant of the KLOTHO Gene and High-density Lipoprotein Cholesterol, Blood Pressure, Stroke, and Longevity Circulation Research. Mar, 2005 | Pubmed ID: 15677572 Biological Evidence for Inheritance of Exceptional Longevity Mechanisms of Ageing and Development. Feb, 2005 | Pubmed ID: 15621216 The Paradox of the Insulin/IGF-1 Signaling Pathway in Longevity Mechanisms of Ageing and Development. Jun, 2004 | Pubmed ID: 15272501 Decrease in Glucose-stimulated Insulin Secretion with Aging is Independent of Insulin Action Diabetes. Feb, 2004 | Pubmed ID: 14747296 Clinical Phenotype of Families with Longevity Journal of the American Geriatrics Society. Feb, 2004 | Pubmed ID: 14728640 Unique Lipoprotein Phenotype and Genotype Associated with Exceptional Longevity JAMA : the Journal of the American Medical Association. Oct, 2003 | Pubmed ID: 14559957 Physiologic Effect of Leptin on Insulin Secretion is Mediated Mainly Through Central Mechanisms FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2003 | Pubmed ID: 12709405 Plasma HDL Levels Highly Correlate with Cognitive Function in Exceptional Longevity The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Nov, 2002 | Pubmed ID: 12403798 Removal of Visceral Fat Prevents Insulin Resistance and Glucose Intolerance of Aging: an Adipokine-mediated Process? Diabetes. Oct, 2002 | Pubmed ID: 12351432 Длиной теломер и теломеразы, Инь и Ян клеточного старения Mary Derasmo Axelrad1, Temuri Budagov1, Gil Atzmon1,2,3 1Department of Medicine, Albert Einstein College of Medicine, 2Diabetes Research and Training Center, Albert Einstein College of Medicine, 3Department of Genetics, Albert Einstein College of Medicine JoVE 50246 Biology
Длиной теломер и теломеразы, Инь и Ян клеточного старения Mary Derasmo Axelrad1, Temuri Budagov1, Gil Atzmon1,2,3 1Department of Medicine, Albert Einstein College of Medicine, 2Diabetes Research and Training Center, Albert Einstein College of Medicine, 3Department of Genetics, Albert Einstein College of Medicine JoVE 50246 Biology