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Articles by Heidi Larkin in JoVE
Snap Chip for Cross-reactivity-free and Spotter-free Multiplexed Sandwich Immunoassays Huiyan Li1,2, Sebastien Bergeron3, Heidi Larkin1,2,3, David Juncker1,2 1McGill University and Génome Québec Innovation Centre, 2Biomedical Engineering Department, McGill University, 3Parallex BioAssays Inc. We demonstrate a snap chip technology for performing cross-reactivity-free multiplexed sandwich immunoassays by simply snapping two slides. A snap apparatus is used for reliably transferring reagents from microarray-to-microarray. The snap chip can be used for any biochemical reactions requiring colocalization of different reagents without cross-contamination.