Henri G.D. Leuvenink Surgical Research Laboratory, Department of Surgery University of Groningen, University Medical Center Groningen Biography Publications Institution JoVE Articles Henri G.D. Leuvenink has not added a biography. If you are Henri G.D. Leuvenink and would like to personalize this page please email our Author Liaison for assistance. Publications Novel Organ Preservation Methods: Not Only Cool but Supercool! Transplantation. Apr, 2015 | Pubmed ID: 25827321 Hydrogen Sulfide in Renal Physiology, Disease and Transplantation--the Smell of Renal Protection Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Apr, 2015 | Pubmed ID: 25656225 Hydrogen Sulfide: Physiological Properties and Therapeutic Potential in Ischaemia British Journal of Pharmacology. Mar, 2015 | Pubmed ID: 25091411 Sodium Thiosulfate Attenuates Angiotensin II-induced Hypertension, Proteinuria and Renal Damage Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2014 | Pubmed ID: 25459997 Hypoxia and Complement-and-Coagulation Pathways in the Deceased Organ Donor As the Major Target for Intervention to Improve Renal Allograft Outcome Transplantation. Nov, 2014 | Pubmed ID: 25427168 Criteria for Viability Assessment of Discarded Human Donor Livers During Ex Vivo Normothermic Machine Perfusion PloS One. 2014 | Pubmed ID: 25369327 Prednisolone Has a Positive Effect on the Kidney but Not on the Liver of Brain Dead Rats: a Potencial Role in Complement Activation Journal of Translational Medicine. 2014 | Pubmed ID: 24884924 Reply: To PMID 24355874 Journal of the American College of Surgeons. May, 2014 | Pubmed ID: 24745572 α-Melanocyte Stimulating Hormone Treatment in Pigs Does Not Improve Early Graft Function in Kidney Transplants from Brain Dead Donors PloS One. 2014 | Pubmed ID: 24728087 Histopathologic and Molecular Evaluation of the Organ Procurement and Transplantation Network Selection Criteria for Intestinal Graft Donation The Journal of Surgical Research. Jun, 2014 | Pubmed ID: 24655665 Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated After Circulatory Death PloS One. 2014 | Pubmed ID: 24551114 Early Angiopoietin-2 Levels After Onset Predict the Advent of Severe Pancreatitis, Multiple Organ Failure, and Infectious Complications in Patients with Acute Pancreatitis Journal of the American College of Surgeons. Jan, 2014 | Pubmed ID: 24355874 Erythropoietin-mediated Protection in Kidney Transplantation: Nonerythropoietic EPO Derivatives Improve Function Without Increasing Risk of Cardiovascular Events Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2014 | Pubmed ID: 23964738 Renoprotective Capacities of Non-erythropoietic EPO Derivative, ARA290, Following Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 24225194 Gaseous Hydrogen Sulfide Protects Against Myocardial Ischemia-reperfusion Injury in Mice Partially Independent from Hypometabolism PloS One. 2013 | Pubmed ID: 23675473 A Human Model of Intra-abdominal Hypertension: Even Slightly Elevated Pressures Lead to Increased Acute Systemic Inflammation and Signs of Acute Kidney Injury Critical Care (London, England). 2013 | Pubmed ID: 23566574 Nonesterified Fatty Acids and Development of Graft Failure in Renal Transplant Recipients Transplantation. Jun, 2013 | Pubmed ID: 23524974 Cystathionine γ-lyase Protects Against Renal Ischemia/reperfusion by Modulating Oxidative Stress Journal of the American Society of Nephrology : JASN. Apr, 2013 | Pubmed ID: 23449534 Are Brain and Heart Tissue Prone to the Development of Thiamine Deficiency? Alcohol (Fayetteville, N.Y.). May, 2013 | Pubmed ID: 23357554 Brain Death Induces Renal Expression of Heme Oxygenase-1 and Heat Shock Protein 70 Journal of Translational Medicine. 2013 | Pubmed ID: 23356498 SLC22A2 is Associated with Tubular Creatinine Secretion and Bias of Estimated GFR in Renal Transplantation Physiological Genomics. Mar, 2013 | Pubmed ID: 23341218 ARA290, a Non-erythropoietic EPO Derivative, Attenuates Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 23302512 UMOD As a Susceptibility Gene for End-stage Renal Disease BMC Medical Genetics. 2012 | Pubmed ID: 22947327 Beneficial Effects of Gaseous Hydrogen Sulfide in Hepatic Ischemia/reperfusion Injury Transplant International : Official Journal of the European Society for Organ Transplantation. Aug, 2012 | Pubmed ID: 22716165 CUBN As a Novel Locus for End-stage Renal Disease: Insights from Renal Transplantation PloS One. 2012 | Pubmed ID: 22574174 Die Wirkung Der Normothermic Umluftkühler Vor Kalten Erhaltung Zur Nach Der Transplantation Schädigung Der Ischemically Beschädigten Spender Nieren Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2012 | Pubmed ID: 22077364 Maschine Perfusion Gegenüber Kühlhaus Für Erhaltung Der Nieren Von Erweiterte Kriterien Spendern Nach Hirntod Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2011 | Pubmed ID: 21332580 Dünndarm-Aufbewahrung Für Darm-Transplantation: Eine Überprüfung Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2011 | Pubmed ID: 21083772 Wie Wichtig Ist Die Dauer Der Hirntod Für Den Ausgang in Nierentransplantation? Transplant International : Official Journal of the European Society for Organ Transplantation. Jan, 2011 | Pubmed ID: 20819191 Maschine Perfusion Gegenüber Kühlhaus Für Die Erhaltung Der Nieren Nach Herztod Spendete: Eine Multizentrische, Randomisierte, Kontrollierte Studie Annals of Surgery. Nov, 2010 | Pubmed ID: 21037431 Der Wert Der Maschine Perfusion Perfusat Biomarker Zur Vorhersage Der Niere Transplant Ergebnis Transplantation. Nov, 2010 | Pubmed ID: 20861807 Reduzierte Ischämie-Reoxygenation Verletzung Ratte Darm Nach Luminalen Erhaltungszustand Mit Eine Maßgeschneiderte Lösung Transplantation. Sep, 2010 | Pubmed ID: 20689496 Heparin Bindung Epidermalen Wachstumsfaktor Renale Ischämie/Reperfusion Verletzungen The Journal of Pathology. Jun, 2010 | Pubmed ID: 20225242 Spender Vorbehandlung Mit Carbamylated Erythropoetin in Einem Hirntod-Modell Reduziert Die Entzündung Effektiver Als Erythropoetin Unter Beibehaltung Der Nierenfunktion Critical Care Medicine. Apr, 2010 | Pubmed ID: 20124889 Severe Thiamine Deficiency Complicated by Weight Loss Protects Against Renal Ischaemia-reperfusion Injury in Rats NDT Plus. Apr, 2009 | Pubmed ID: 25949326 Der Einfluss Des Verstorbenen Spenders Alter Und Alt-für Alte Zuteilung Auf Niere Transplant Ergebnis Transplantation. Aug, 2009 | Pubmed ID: 19696638 Erhöhte Intestinale Permeabilität Bei Verstorbenen Gehirn Tote Ratten Transplantation. Aug, 2009 | Pubmed ID: 19667953 Hydrogen Sulfide-induced Hypometabolism Prevents Renal Ischemia/reperfusion Injury Journal of the American Society of Nephrology : JASN. Sep, 2009 | Pubmed ID: 19628669 The Goddess of the Waters Kidney International. Apr, 2009 | Pubmed ID: 19337215 Maschine Perfusion Oder Kühlhaus in Verstorbenen Spenders Nierentransplantation The New England Journal of Medicine. Jan, 2009 | Pubmed ID: 19118301 Verschlechterung Der Endothelzellen Und Glatten Muskel-Zellfunktion in DCD Nieren Nach Statischen Kühlhaus in IGL-1 Oder UW The Journal of Surgical Research. Apr, 2009 | Pubmed ID: 18701116 Hirntod Induziert Entzündungen Im Darm Spender Transplantation. Jul, 2008 | Pubmed ID: 18622292 Frühe Veranstaltungen in Nieren-Spende: Fortschreiten Der Endothelial Aktivierung, Oxidativer Stress Und Tubuläre Schädigung Nach Hirntod American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. May, 2008 | Pubmed ID: 18318776 Statische Kühlhaus Bewahrung Der Ischemically Beschädigten Nieren. Ein Vergleich Zwischen IGL-1 Und UW-Lösung Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2008 | Pubmed ID: 18225993 Niere Funktionsaufnahme Nach Erhalt Mit Einem Neuartigen Unterkühlt Maschine Perfusion Verbessert Annals of Surgery. Dec, 2007 | Pubmed ID: 18043100 Das Allmähliche Beginn Hirntod-Modell: Ein Modell Zur Organspende Und Seine Auswirkungen Auf Das Ergebnis Nach Der Transplantation Zu Studieren Laboratory Animals. Jul, 2007 | Pubmed ID: 17640464 Perspektiven in Der Erhaltung Der Orgel Transplantation. May, 2007 | Pubmed ID: 17519776 Tissue Thiamine Deficiency As Potential Cause of Delayed Graft Function After Kidney Transplantation: Thiamine Supplementation of Kidney Donors May Improve Transplantation Outcome Medical Hypotheses. 2007 | Pubmed ID: 17379423 Bestimmung Der Eine Ausreichende Perfusion-Druck Für Kontinuierliche Dual Schiff Unterkühlt Maschine Perfusion Der Ratte-Leber Transplant International : Official Journal of the European Society for Organ Transplantation. Apr, 2007 | Pubmed ID: 17326775 Non-Herzen Schlagen Organspende: Übersicht Und Zukunftsperspektiven Transplant International : Official Journal of the European Society for Organ Transplantation. Jul, 2007 | Pubmed ID: 17263786 Raumzeitliche Ausdruck Des Häm-Oxygenase-1 Nach Hepatische Ischämie in HO-1/Luc Mäuse Von In-vivo Biolumineszenz Erkannt Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2006 | Pubmed ID: 17058249 Akute Isovolemic Hemodilution Löst Proinflammatory Und Procoagulatory Endotheliale Aktivierung in Lebenswichtigen Organen: Rolle Der Aggregation Der Erythrozyten Microcirculation (New York, N.Y. : 1994). Jul-Aug, 2006 | Pubmed ID: 16815825 Cytoprotective Dosen Von Erythropoetin Oder Carbamylated Erythropoetin Haben Deutlich Unterschiedliche Prokoagulans Und Vasoaktive Aktivitäten Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006 | Pubmed ID: 16585502 Hepatic Expression of ABC Transporters G5 and G8 Does Not Correlate with Biliary Cholesterol Secretion in Liver Transplant Patients Hepatology (Baltimore, Md.). Nov, 2005 | Pubmed ID: 16250035 Sauerstoffversorgung Während Hypothermie Rattenleberzellen Erhaltung: Eine In-vitro-Scheibe-Studie Vorteilhaft Oder Toxische Sauerstoffversorgung Effekte Nachweisen Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2005 | Pubmed ID: 16237692 Expression of Heme Oxygenase-1 in Human Livers Before Transplantation Correlates with Graft Injury and Function After Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2005 | Pubmed ID: 15996234 Rapid Increase of Bile Salt Secretion is Associated with Bile Duct Injury After Human Liver Transplantation Journal of Hepatology. Dec, 2004 | Pubmed ID: 15582136 Deutliche Veränderungen in Der Transkriptionellen Spendernieren Auf Hirntod Induktion Bei Ratten: Einblicke in Die Prozesse Der Hirntod American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2004 | Pubmed ID: 15575899 Auswirkung Der Hirntod Auf Die Genexpression Und Aktivierung Gewebe Im Menschlichen Spendernieren Transplantation. Oct, 2004 | Pubmed ID: 15480162 Erste Blut Auswaschung Während Der Beschaffung Von Organen Bestimmt, Leberschäden Und Funktion Nach Konservierung Und Reperfusion American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2004 | Pubmed ID: 15476484 Auswirkung Der University of Wisconsin-Organ-Aufbewahrungs-Flüssigkeit Auf Hämorheologie Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2004 | Pubmed ID: 15146313 Hypothermer Maschine Erhaltung in Lebertransplantation Revisited: Konzepte Und Kriterien in Das Neue Jahrtausend Annals of Biomedical Engineering. Apr, 2004 | Pubmed ID: 15117035 Wirkung Von Hirntod Und Nicht-Herz-Schlagen Nierenspende Auf Die Nierenfunktion Und Verletzungen: Eine Einschätzung in Der Isolierten Perfundierten Rattenniere Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. Dec, 2003 | Pubmed ID: 15859914 Macrophage Overgrowth Affects Neighboring Nonovergrown Encapsulated Islets The Journal of Surgical Research. Dec, 2003 | Pubmed ID: 14697289 Effective Removal of Alginate-poly-L-lysine Microcapsules from Pancreatic Islets by Use of Trypsin-EDTA Journal of Biomedical Materials Research. Part A. Nov, 2003 | Pubmed ID: 14566813 Beziehung Zwischen Der Dauer Des Hirntodes Und Hämodynamischen (In-) Stabilität Auf Progressive Immunologische Dysfunktion Und Erhöhte Aktivierung Der Spendernieren Kidney International. Nov, 2003 | Pubmed ID: 14531823 Hyperaggregating Wirkung Von Hydroxyethylstärke Komponenten Und University of Wisconsin-Lösung Auf Die Menschliche Rote Blutzellen: Ein Risiko Der Beeinträchtigung Von Transplantat Perfusion in Der Beschaffung Von Organen? Transplantation. Jul, 2003 | Pubmed ID: 12865783 Ex-situ-normothermen Maschine Perfusion von Spenderlebern Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine
Ex-situ-normothermen Maschine Perfusion von Spenderlebern Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine