Hiroyuki Takeda Proteo-Science Center Ehime University Biography Publications Institution JoVE Articles Hiroyuki Takeda has not added a biography. If you are Hiroyuki Takeda and would like to personalize this page please email our Author Liaison for assistance. Publications KN3014, a Piperidine-containing Small Compound, Inhibits Auto-secretion of IL-1β from PBMCs in a Patient with Muckle-Wells Syndrome Scientific Reports. Aug, 2020 | Pubmed ID: 32782316 Production of a Rabbit Monoclonal Antibody for Highly Sensitive Detection of Citrus Mosaic Virus and Related Viruses PloS One. 2020 | Pubmed ID: 32294099 Biophysical Characterization of the Breast Cancer-related BIG3-PHB2 Interaction: Effect of Non-conserved Loop Region of BIG3 on the Structure and the Interaction Biochemical and Biophysical Research Communications. 10, 2019 | Pubmed ID: 31421830 Amyloid β Directly Interacts with NLRP3 to Initiate Inflammasome Activation: Identification of an Intrinsic NLRP3 Ligand in a Cell-free System Inflammation and Regeneration. 2018 | Pubmed ID: 30459926 Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30244457 Production of Immunizing Antigen Proteoliposome Using Cell-Free Protein Synthesis System Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30244454 Engineered Membrane Protein Antigens Successfully Induce Antibodies Against Extracellular Regions of Claudin-5 Scientific Reports. 05, 2018 | Pubmed ID: 29849184 Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes Frontiers in Pharmacology. 2018 | Pubmed ID: 29467651 DANFIN Functions As an Inhibitor of Transcription Factor NF-κB and Potentiates the Antitumor Effect of Bortezomib in Multiple Myeloma Biochemical and Biophysical Research Communications. 01, 2018 | Pubmed ID: 29284118 Applications of Reconstituted Inflammasomes in a Cell-free System to Drug Discovery and Elucidation of the Pathogenesis of Autoinflammatory Diseases Inflammation and Regeneration. 2017 | Pubmed ID: 29259708 Claudin-5-Binders Enhance Permeation of Solutes Across the Blood-Brain Barrier in a Mammalian Model The Journal of Pharmacology and Experimental Therapeutics. 11, 2017 | Pubmed ID: 28819070 Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models Journal of Immunology (Baltimore, Md. : 1950). 09, 2017 | Pubmed ID: 28716825 CP5 System, for Simple and Highly Efficient Protein Purification with a C-terminal Designed Mini Tag PloS One. 2017 | Pubmed ID: 28542437 Angubindin-1, a Novel Paracellular Absorption Enhancer Acting at the Tricellular Tight Junction Journal of Controlled Release : Official Journal of the Controlled Release Society. 08, 2017 | Pubmed ID: 28528740 Interaction Between RNF8 and DYRK2 is Required for the Recruitment of DNA Repair Molecules to DNA Double-strand Breaks FEBS Letters. Mar, 2017 | Pubmed ID: 28194753 Linear Ubiquitination is Involved in the Pathogenesis of Optineurin-associated Amyotrophic Lateral Sclerosis Nature Communications. 08, 2016 | Pubmed ID: 27552911 Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis TheScientificWorldJournal. 2016 | Pubmed ID: 27403452 AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody Against Human Dopamine Receptor D1 for Protein Analysis PloS One. 2016 | Pubmed ID: 27271343 Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction Between E3 Ligases and Substrate Proteins PloS One. 2016 | Pubmed ID: 27249653 Wheat Germ-based Protein Libraries for the Functional Characterisation of the Arabidopsis E2 Ubiquitin Conjugating Enzymes and the RING-type E3 Ubiquitin Ligase Enzymes BMC Plant Biology. Nov, 2015 | Pubmed ID: 26556605 Reconstituted AIM2 Inflammasome in Cell-free System Journal of Immunological Methods. Nov, 2015 | Pubmed ID: 26259507 Na, K-ATPase α3 is a Death Target of Alzheimer Patient Amyloid-β Assembly Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26224839 Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model The Journal of Pharmacology and Experimental Therapeutics. Sep, 2015 | Pubmed ID: 26139628 Novel Autoantigens Associated with Lupus Nephritis PloS One. 2015 | Pubmed ID: 26098692 Production of Monoclonal Antibodies Against GPCR Using Cell-free Synthesized GPCR Antigen and Biotinylated Liposome-based Interaction Assay Scientific Reports. Jun, 2015 | Pubmed ID: 26061673 High-throughput Synthesis of Stable Isotope-labeled Transmembrane Proteins for Targeted Transmembrane Proteomics Using a Wheat Germ Cell-free Protein Synthesis System Molecular BioSystems. Feb, 2015 | Pubmed ID: 25431973 The Ligand Binding Ability of Dopamine D1 Receptors Synthesized Using a Wheat Germ Cell-free Protein Synthesis System with Liposomes European Journal of Pharmacology. Dec, 2014 | Pubmed ID: 25446930 [Cell-free Based Protein Array Technology for Analyses of Protein Kinases and Ubiquitin Ligases] Seikagaku. The Journal of Japanese Biochemical Society. Jun, 2013 | Pubmed ID: 23875471 Genome-wide Biochemical Analysis of Arabidopsis Protein Phosphatase Using a Wheat Cell-free System FEBS Letters. Sep, 2012 | Pubmed ID: 22968126 إنتاج البروتينات الخالية من الخلايا للتحليل الوظيفي وتطوير الأجسام المضادة التي تستهدف البروتينات الغشائية Wei Zhou1, Hiroyuki Takeda2 1Graduate School of Medicine, Ehime University, 2Proteo-Science Center, Ehime University JoVE 61871 Biochemistry
إنتاج البروتينات الخالية من الخلايا للتحليل الوظيفي وتطوير الأجسام المضادة التي تستهدف البروتينات الغشائية Wei Zhou1, Hiroyuki Takeda2 1Graduate School of Medicine, Ehime University, 2Proteo-Science Center, Ehime University JoVE 61871 Biochemistry