Hiroyuki Takeda

Publications

• KN3014, a Piperidine-containing Small Compound, Inhibits Auto-secretion of IL-1β from PBMCs in a Patient with Muckle-Wells Syndrome
  Scientific Reports. Aug, 2020  |   Pubmed ID: 32782316
• Production of a Rabbit Monoclonal Antibody for Highly Sensitive Detection of Citrus Mosaic Virus and Related Viruses
  PloS One. 2020  |   Pubmed ID: 32294099
• Biophysical Characterization of the Breast Cancer-related BIG3-PHB2 Interaction: Effect of Non-conserved Loop Region of BIG3 on the Structure and the Interaction
  Biochemical and Biophysical Research Communications. 10, 2019  |   Pubmed ID: 31421830
• Amyloid β Directly Interacts with NLRP3 to Initiate Inflammasome Activation: Identification of an Intrinsic NLRP3 Ligand in a Cell-free System
  Inflammation and Regeneration. 2018  |   Pubmed ID: 30459926
• Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 30244457
• Production of Immunizing Antigen Proteoliposome Using Cell-Free Protein Synthesis System
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 30244454
• Engineered Membrane Protein Antigens Successfully Induce Antibodies Against Extracellular Regions of Claudin-5
  Scientific Reports. 05, 2018  |   Pubmed ID: 29849184
• Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes
  Frontiers in Pharmacology. 2018  |   Pubmed ID: 29467651
• DANFIN Functions As an Inhibitor of Transcription Factor NF-κB and Potentiates the Antitumor Effect of Bortezomib in Multiple Myeloma
  Biochemical and Biophysical Research Communications. 01, 2018  |   Pubmed ID: 29284118
• Applications of Reconstituted Inflammasomes in a Cell-free System to Drug Discovery and Elucidation of the Pathogenesis of Autoinflammatory Diseases
  Inflammation and Regeneration. 2017  |   Pubmed ID: 29259708
• Claudin-5-Binders Enhance Permeation of Solutes Across the Blood-Brain Barrier in a Mammalian Model
  The Journal of Pharmacology and Experimental Therapeutics. 11, 2017  |   Pubmed ID: 28819070
• Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models
  Journal of Immunology (Baltimore, Md. : 1950). 09, 2017  |   Pubmed ID: 28716825
• CP5 System, for Simple and Highly Efficient Protein Purification with a C-terminal Designed Mini Tag
  PloS One. 2017  |   Pubmed ID: 28542437
• Angubindin-1, a Novel Paracellular Absorption Enhancer Acting at the Tricellular Tight Junction
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 08, 2017  |   Pubmed ID: 28528740
• Interaction Between RNF8 and DYRK2 is Required for the Recruitment of DNA Repair Molecules to DNA Double-strand Breaks
  FEBS Letters. Mar, 2017  |   Pubmed ID: 28194753
• Linear Ubiquitination is Involved in the Pathogenesis of Optineurin-associated Amyotrophic Lateral Sclerosis
  Nature Communications. 08, 2016  |   Pubmed ID: 27552911
• Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis
  TheScientificWorldJournal. 2016  |   Pubmed ID: 27403452
• AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody Against Human Dopamine Receptor D1 for Protein Analysis
  PloS One. 2016  |   Pubmed ID: 27271343
• Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction Between E3 Ligases and Substrate Proteins
  PloS One. 2016  |   Pubmed ID: 27249653
• Wheat Germ-based Protein Libraries for the Functional Characterisation of the Arabidopsis E2 Ubiquitin Conjugating Enzymes and the RING-type E3 Ubiquitin Ligase Enzymes
  BMC Plant Biology. Nov, 2015  |   Pubmed ID: 26556605
• Reconstituted AIM2 Inflammasome in Cell-free System
  Journal of Immunological Methods. Nov, 2015  |   Pubmed ID: 26259507
• Na, K-ATPase α3 is a Death Target of Alzheimer Patient Amyloid-β Assembly
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015  |   Pubmed ID: 26224839
• Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2015  |   Pubmed ID: 26139628
• Novel Autoantigens Associated with Lupus Nephritis
  PloS One. 2015  |   Pubmed ID: 26098692
• Production of Monoclonal Antibodies Against GPCR Using Cell-free Synthesized GPCR Antigen and Biotinylated Liposome-based Interaction Assay
  Scientific Reports. Jun, 2015  |   Pubmed ID: 26061673
• High-throughput Synthesis of Stable Isotope-labeled Transmembrane Proteins for Targeted Transmembrane Proteomics Using a Wheat Germ Cell-free Protein Synthesis System
  Molecular BioSystems. Feb, 2015  |   Pubmed ID: 25431973
• The Ligand Binding Ability of Dopamine D1 Receptors Synthesized Using a Wheat Germ Cell-free Protein Synthesis System with Liposomes
  European Journal of Pharmacology. Dec, 2014  |   Pubmed ID: 25446930
• [Cell-free Based Protein Array Technology for Analyses of Protein Kinases and Ubiquitin Ligases]
  Seikagaku. The Journal of Japanese Biochemical Society. Jun, 2013  |   Pubmed ID: 23875471
• Genome-wide Biochemical Analysis of Arabidopsis Protein Phosphatase Using a Wheat Cell-free System
  FEBS Letters. Sep, 2012  |   Pubmed ID: 22968126