Howard D. White Department of Physiological Sciences Eastern Virginia Medical School Biography Publications Institution JoVE Articles Howard D. White has not added a biography. If you are Howard D. White and would like to personalize this page please email our Author Liaison for assistance. Publications On-grid and In-flow Mixing for Time-resolved Cryo-EM Acta Crystallographica. Section D, Structural Biology. Oct, 2021 | Pubmed ID: 34605427 Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin Journal of Molecular Biology. 09, 2021 | Pubmed ID: 34329643 The Structure of the Native Cardiac Thin Filament at Systolic Ca Levels Proceedings of the National Academy of Sciences of the United States of America. 03, 2021 | Pubmed ID: 33753506 High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex Structure (London, England : 1993). 01, 2021 | Pubmed ID: 33065066 Need for Speed: Examining Protein Behavior During CryoEM Grid Preparation at Different Timescales Structure (London, England : 1993). 11, 2020 | Pubmed ID: 32814033 Sample Deposition Onto Cryo-EM Grids: from Sprays to Jets and Back Acta Crystallographica. Section D, Structural Biology. Apr, 2020 | Pubmed ID: 32254058 A Cryo-EM Grid Preparation Device for Time-resolved Structural Studies IUCrJ. Nov, 2019 | Pubmed ID: 31709058 Investigation into the Mechanism of Thin Filament Regulation by Transient Kinetics and Equilibrium Binding: Is There a Conflict? The Journal of General Physiology. 05, 2019 | Pubmed ID: 30824574 N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament Structure (London, England : 1993). 12, 2018 | Pubmed ID: 30270174 Distinct Sites in Tropomyosin Specify Shared and Isoform-specific Regulation of Myosins II and V Cytoskeleton (Hoboken, N.J.). 04, 2018 | Pubmed ID: 29500902 The Shaker-1 Mouse Myosin VIIa Deafness Mutation Results in a Severely Reduced Rate of the ATP Hydrolysis Step The Journal of Biological Chemistry. 01, 2018 | Pubmed ID: 29167268 Ca-induced Movement of Tropomyosin on Native Cardiac Thin Filaments Revealed by Cryoelectron Microscopy Proceedings of the National Academy of Sciences of the United States of America. 06, 2017 | Pubmed ID: 28607071 C0 and C1 N-terminal Ig Domains of Myosin Binding Protein C Exert Different Effects on Thin Filament Activation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26831109 Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine β-cardiac Myosin Biochemistry. Mar, 2015 | Pubmed ID: 25680381 Modulation of Thin Filament Activation of Myosin ATP Hydrolysis by N-terminal Domains of Cardiac Myosin Binding Protein-C Biochemistry. Oct, 2014 | Pubmed ID: 25265574 Coupling of Two Non-processive Myosin 5c Dimers Enables Processive Stepping Along Actin Filaments Scientific Reports. May, 2014 | Pubmed ID: 24809456 Regulation of Actin-myosin Interaction by Conserved Periodic Sites of Tropomyosin Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23091026 Mechanism of Regulation of Native Cardiac Muscle Thin Filaments by Rigor Cardiac Myosin-S1 and Calcium The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20696756 The SAH Domain Extends the Functional Length of the Myosin Lever Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 20018767 Switch 1 Mutation S217A Converts Myosin V into a Low Duty Ratio Motor The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19008235 Direct Observation of the Mechanochemical Coupling in Myosin Va During Processive Movement Nature. Sep, 2008 | Pubmed ID: 18668042 Smooth Muscle Myosin Phosphorylated at Single Head Shows Sustained Mechanical Activity The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18408003 Kinetics of ADP Dissociation from the Trail and Lead Heads of Actomyosin V Following the Power Stroke The Journal of Biological Chemistry. Jan, 2008 | Pubmed ID: 17965414 Real-time Measurement of Myosin-nucleotide Noncovalent Complexes by Electrospray Ionization Mass Spectrometry Biophysical Journal. Aug, 2007 | Pubmed ID: 17483158 Kinetic Mechanism of MyosinV-S1 Using a New Fluorescent ATP Analogue Biochemistry. Oct, 2006 | Pubmed ID: 17059220 The Prepower Stroke Conformation of Myosin V The Journal of Cell Biology. Dec, 2002 | Pubmed ID: 12499355 Mechanism of Regulation of Phosphate Dissociation from Actomyosin-ADP-Pi by Thin Filament Proteins Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12486217 Observation of Transient Disorder During Myosin Subfragment-1 Binding to Actin by Stopped-flow Fluorescence and Millisecond Time Resolution Electron Cryomicroscopy: Evidence That the Start of the Crossbridge Power Stroke in Muscle Has Variable Geometry Proceedings of the National Academy of Sciences of the United States of America. Jan, 1999 | Pubmed ID: 9892656 Preparación rápida de la rejilla para la crio-microscopía electrónica resuelta en el tiempo David P. Klebl1, Frank Sobott2, Howard D. White3, Stephen P. Muench1 1School of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 2School of Molecular and Cellular Biology, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 3Department of Physiological Sciences, Eastern Virginia Medical School JoVE 62199 Biochemistry
Preparación rápida de la rejilla para la crio-microscopía electrónica resuelta en el tiempo David P. Klebl1, Frank Sobott2, Howard D. White3, Stephen P. Muench1 1School of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 2School of Molecular and Cellular Biology, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 3Department of Physiological Sciences, Eastern Virginia Medical School JoVE 62199 Biochemistry
