Howard S. Fox

Publications

• Chronic Morphine Administration Differentially Modulates Viral Reservoirs in SIVmac251 Infected Rhesus Macaque Model
  Journal of Virology. Dec, 2020  |   Pubmed ID: 33328304
• Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis
  Viruses. 11, 2020  |   Pubmed ID: 33198269
• The Age-related Trajectory of Visual Attention Neural Function is Altered in Adults Living with HIV: A Cross-sectional MEG Study
  EBioMedicine. Nov, 2020  |   Pubmed ID: 33099087
• Pharmacologic Approaches to HIV-associated Neurocognitive Disorders
  Current Opinion in Pharmacology. Oct, 2020  |   Pubmed ID: 33049585
• Prefrontal Gating of Sensory Input Differentiates Cognitively Impaired and Unimpaired Aging Adults with HIV
  Brain Communications. 2020  |   Pubmed ID: 32954330
• Association of Epigenetic Metrics of Biological Age With Cortical Thickness
  JAMA Network Open. 09, 2020  |   Pubmed ID: 32926115
• Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop
  Pathogens & Immunity. 2020  |   Pubmed ID: 32856008
• Deletion of DJ-1 in Rats Affects Protein Abundance and Mitochondrial Function at the Synapse
  Scientific Reports. 08, 2020  |   Pubmed ID: 32792613
• Interactions of Monocytes, HIV, and ART Identified by an Innovative ScRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities
  MBio. 07, 2020  |   Pubmed ID: 32723919
• HIV-1 Tat-mediated Astrocytic Amyloidosis involves the HIF-1α/lncRNA BACE1-AS Axis
  PLoS Biology. 05, 2020  |   Pubmed ID: 32453744
• A Year-long Extended Release Nanoformulated Cabotegravir Prodrug
  Nature Materials. 08, 2020  |   Pubmed ID: 32341511
• Interactive Effects of HIV and Ageing on Neural Oscillations: Independence from Neuropsychological Performance
  Brain Communications. 2020  |   Pubmed ID: 32322820
• Age-related Visual Dynamics in HIV-infected Adults with Cognitive Impairment
  Neurology(R) Neuroimmunology & Neuroinflammation. 05, 2020  |   Pubmed ID: 32102916
• Epigenetic Markers of Aging Predict the Neural Oscillations Serving Selective Attention
  Cerebral Cortex (New York, N.Y. : 1991). 03, 2020  |   Pubmed ID: 31504270
• Defining Cerebrospinal Fluid HIV RNA Escape: Editorial Review AIDS
  AIDS (London, England). 12, 2019  |   Pubmed ID: 31790376
• Creation of a Long-acting Rilpivirine Prodrug Nanoformulation
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 10, 2019  |   Pubmed ID: 31491432
• Secreted Metabolome of Human Macrophages Exposed to Methamphetamine
  Analytical Chemistry. 07, 2019  |   Pubmed ID: 31265257
• Downregulation of an Evolutionary Young MiR-1290 in an IPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder
  Stem Cells International. 2019  |   Pubmed ID: 31191687
• Quantitative Proteomics of Presynaptic Mitochondria Reveal an Overexpression and Biological Relevance of Neuronal MitoNEET in Postnatal Brain Development
  Developmental Neurobiology. 04, 2019  |   Pubmed ID: 31050203
• A Mouse Model of Seizures in Anti-N-methyl-d-aspartate Receptor Encephalitis
  Epilepsia. 03, 2019  |   Pubmed ID: 30740690
• The Integrated National NeuroAIDS Tissue Consortium Database: a Rich Platform for NeuroHIV Research
  Database : the Journal of Biological Databases and Curation. 01, 2019  |   Pubmed ID: 30624650
• Pharmacokinetic Testing of a First-generation Cabotegravir Prodrug in Rhesus Macaques
  AIDS (London, England). 03, 2019  |   Pubmed ID: 30289818
• Neural Dynamics of Selective Attention Deficits in HIV-associated Neurocognitive Disorder
  Neurology. 11, 2018  |   Pubmed ID: 30333162
• Proteomic and Functional Data Sets on Synaptic Mitochondria from Rats with Genetic Ablation of
  Data in Brief. Oct, 2018  |   Pubmed ID: 30197913
• Aberrant Oscillatory Dynamics During Somatosensory Processing in HIV-infected Adults
  NeuroImage. Clinical. 2018  |   Pubmed ID: 30094159
• Molecular Mechanisms of Long Noncoding RNAs and Their Role in Disease Pathogenesis
  Oncotarget. Apr, 2018  |   Pubmed ID: 29719633
• Aberrant Occipital Dynamics Differentiate HIV-infected Patients with and Without Cognitive Impairment
  Brain : a Journal of Neurology. 06, 2018  |   Pubmed ID: 29672678
• Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution
  Theranostics. 2018  |   Pubmed ID: 29290806
• Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 06, 2018  |   Pubmed ID: 29280055
• Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques
  Antimicrobial Agents and Chemotherapy. 01, 2018  |   Pubmed ID: 29061742
• Creation of a Nanoformulated Cabotegravir Prodrug with Improved Antiretroviral Profiles
  Biomaterials. Jan, 2018  |   Pubmed ID: 29059541
• Central Nervous System-penetrating Antiretrovirals Impair Energetic Reserve in Striatal Nerve Terminals
  Journal of Neurovirology. Dec, 2017  |   Pubmed ID: 28895059
• Osteopontin Impacts Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points
  Mediators of Inflammation. 2017  |   Pubmed ID: 28811681
• Induction of MiR-155 After Brain Injury Promotes Type 1 Interferon and Has a Neuroprotective Effect
  Frontiers in Molecular Neuroscience. 2017  |   Pubmed ID: 28804446
• Measures of Physical and Mental Independence Among HIV-Positive Individuals: Impact of Substance Use Disorder
  AIDS Research and Human Retroviruses. Oct, 2017  |   Pubmed ID: 28288515
• Tat-Mediated Induction of MiRs-34a & -138 Promotes Astrocytic Activation Via Downregulation of SIRT1: Implications for Aging in HAND
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Feb, 2017  |   Pubmed ID: 28236278
• Aberrant Neuronal Dynamics During Working Memory Operations in the Aging HIV-Infected Brain
  Scientific Reports. 02, 2017  |   Pubmed ID: 28155864
• Emerging Roles of Extracellular Vesicles in Neurodegenerative Disorders: Focus on HIV-associated Neurological Complications
  Cell Death & Disease. Nov, 2016  |   Pubmed ID: 27882942
• SWATH-MS Proteome Profiling Data Comparison of DJ-1, Parkin, and PINK1 Knockout Rat Striatal Mitochondria
  Data in Brief. Dec, 2016  |   Pubmed ID: 27761515
• Loss of Pink1 Modulates Synaptic Mitochondrial Bioenergetics in the Rat Striatum Prior to Motor Symptoms: Concomitant Complex I Respiratory Defects and Increased Complex II-mediated Respiration
  Proteomics. Clinical Applications. 12, 2016  |   Pubmed ID: 27568932
• Traumatic Brain Injury Increases Levels of MiR-21 in Extracellular Vesicles: Implications for Neuroinflammation
  FEBS Open Bio. 08, 2016  |   Pubmed ID: 27516962
• Metabolic Drift in the Aging Brain
  Aging. 05, 2016  |   Pubmed ID: 27182841
• Methamphetamine Abuse Affects Gene Expression in Brain-derived Microglia of SIV-infected Macaques to Enhance Inflammation and Promote Virus Targets
  BMC Immunology. 04, 2016  |   Pubmed ID: 27107567
• Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA
  Molecular Cell. 04, 2016  |   Pubmed ID: 27105112
• Neonatal Mitochondrial Abnormalities Due to PINK1 Deficiency: Proteomics Reveals Early Changes Relevant to Parkinson׳s Disease
  Data in Brief. Mar, 2016  |   Pubmed ID: 26866053
• HIV-1 Transgenic Rats Display Mitochondrial Abnormalities Consistent with Abnormal Energy Generation and Distribution
  Journal of Neurovirology. 10, 2016  |   Pubmed ID: 26843384
• The Proteomic Characterization of Plasma or Serum from HIV-Infected Patients
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26714720
• Early Expression of Parkinson's Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats
  Molecular Neurobiology. Jan, 2016  |   Pubmed ID: 25421206
• Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB
  Alcoholism, Clinical and Experimental Research. Dec, 2015  |   Pubmed ID: 26556759
• Coexpression Network Analysis of MiRNA-142 Overexpression in Neuronal Cells
  BioMed Research International. 2015  |   Pubmed ID: 26539539
• Phenotypic Changes in the Brain of SIV-infected Macaques Exposed to Methamphetamine Parallel Macrophage Activation Patterns Induced by the Common Gamma-chain Cytokine System
  Frontiers in Microbiology. 2015  |   Pubmed ID: 26441851
• The National NeuroAIDS Tissue Consortium (NNTC) Database: an Integrated Database for HIV-related Studies
  Database : the Journal of Biological Databases and Curation. 2015  |   Pubmed ID: 26228431
• Data for Mitochondrial Proteomic Alterations in the Aging Mouse Brain
  Data in Brief. Sep, 2015  |   Pubmed ID: 26217775
• MiR-21 in Extracellular Vesicles Leads to Neurotoxicity Via TLR7 Signaling in SIV Neurological Disease
  PLoS Pathogens. Jul, 2015  |   Pubmed ID: 26154133
• Chronic SIV and Morphine Treatment Increases Heat Shock Protein 5 Expression at the Synapse
  Journal of Neurovirology. Oct, 2015  |   Pubmed ID: 26037114
• Proteomic Analysis and Functional Characterization of Mouse Brain Mitochondria During Aging Reveal Alterations in Energy Metabolism
  Proteomics. May, 2015  |   Pubmed ID: 25546256
• Multimodal Neuroimaging Evidence of Alterations in Cortical Structure and Function in HIV-infected Older Adults
  Human Brain Mapping. Mar, 2015  |   Pubmed ID: 25376125
• CD8+ T Cells Maintain Suppression of Simian Immunodeficiency Virus in the Central Nervous System
  The Journal of Infectious Diseases. Jan, 2015  |   Pubmed ID: 25035516
• Data for Mitochondrial Proteomic Alterations in the Developing Rat Brain
  Data in Brief. Dec, 2014  |   Pubmed ID: 26217684
• Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death when Immune Cells Are Activated by Pertussis Toxin
  Mediators of Inflammation. 2014  |   Pubmed ID: 25525298
• Brain Region Mapping Using Global Metabolomics
  Chemistry & Biology. Nov, 2014  |   Pubmed ID: 25457182
• A New Rhesus Macaque Assembly and Annotation for Next-generation Sequencing Analyses
  Biology Direct. Oct, 2014  |   Pubmed ID: 25319552
• Enhanced Methamphetamine Metabolism in Rhesus Macaque As Compared with Human: an Analysis Using a Novel Method of Liquid Chromatography with Tandem Mass Spectrometry, Kinetic Study, and Substrate Docking
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. Dec, 2014  |   Pubmed ID: 25301936
• Pharmacokinetics, Biodistribution, and Toxicity of Folic Acid-coated Antiretroviral Nanoformulations
  Antimicrobial Agents and Chemotherapy. Dec, 2014  |   Pubmed ID: 25288084
• Efavirenz Induces Neuronal Autophagy and Mitochondrial Alterations
  The Journal of Pharmacology and Experimental Therapeutics. Nov, 2014  |   Pubmed ID: 25161171
• Proteomic Analysis of the Mitochondria from Embryonic and Postnatal Rat Brains Reveals Response to Developmental Changes in Energy Demands
  Journal of Proteomics. Sep, 2014  |   Pubmed ID: 25046836
• Aging Synaptic Mitochondria Exhibit Dynamic Proteomic Changes While Maintaining Bioenergetic Function
  Aging. Apr, 2014  |   Pubmed ID: 24827396
• Cellular Interactions and Signaling in NeuroAIDS: Emerging Issues Colloquium
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jun, 2014  |   Pubmed ID: 24789373
• Quantitative Proteomics of Synaptic and Nonsynaptic Mitochondria: Insights for Synaptic Mitochondrial Vulnerability
  Journal of Proteome Research. May, 2014  |   Pubmed ID: 24708184
• The 20th Scientific Conference of the Society on NeuroImmune Pharmacology
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2014  |   Pubmed ID: 24573530
• Quantitative Proteomics by SWATH-MS Reveals Altered Expression of Nucleic Acid Binding and Regulatory Proteins in HIV-1-infected Macrophages
  Journal of Proteome Research. Apr, 2014  |   Pubmed ID: 24564501
• Decreased MEG Beta Oscillations in HIV-infected Older Adults During the Resting State
  Journal of Neurovirology. Dec, 2013  |   Pubmed ID: 24297500
• Biomarkers for NeuroAIDS: Recent Progress in the Field
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2013  |   Pubmed ID: 24292958
• MicroRNA-142 Reduces Monoamine Oxidase A Expression and Activity in Neuronal Cells by Downregulating SIRT1
  PloS One. 2013  |   Pubmed ID: 24244526
• Combined Fluorescent in Situ Hybridization for Detection of MicroRNAs and Immunofluorescent Labeling for Cell-type Markers
  Frontiers in Cellular Neuroscience. 2013  |   Pubmed ID: 24065888
• Quantitative Proteomics Reveals Oxygen-dependent Changes in Neuronal Mitochondria Affecting Function and Sensitivity to Rotenone
  Journal of Proteome Research. Oct, 2013  |   Pubmed ID: 23971408
• Autophagy-mediated Turnover of Dynamin-related Protein 1
  BMC Neuroscience. Aug, 2013  |   Pubmed ID: 23937156
• Pilot Study of Younger and Older HIV-infected Adults Using Traditional and Novel Functional Assessments
  HIV Clinical Trials. Jul-Aug, 2013  |   Pubmed ID: 23924589
• Abnormal MEG Oscillatory Activity During Visual Processing in the Prefrontal Cortices and Frontal Eye-fields of the Aging HIV Brain
  PloS One. 2013  |   Pubmed ID: 23840428
• Transcriptome Meta-analysis Reveals a Central Role for Sex Steroids in the Degeneration of Hippocampal Neurons in Alzheimer's Disease
  BMC Systems Biology. Jun, 2013  |   Pubmed ID: 23803348
• Up-regulation of MicroRNA-142 in Simian Immunodeficiency Virus Encephalitis Leads to Repression of Sirtuin1
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2013  |   Pubmed ID: 23752207
• Functional Brain Abnormalities During Finger-tapping in HIV-infected Older Adults: a Magnetoencephalography Study
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2013  |   Pubmed ID: 23749418
• Preclinical Pharmacokinetics and Tissue Distribution of Long-acting Nanoformulated Antiretroviral Therapy
  Antimicrobial Agents and Chemotherapy. Jul, 2013  |   Pubmed ID: 23612193
• N-methyl-D-aspartate Receptor-mediated Axonal Injury in Adult Rat Corpus Callosum
  Journal of Neuroscience Research. Feb, 2013  |   Pubmed ID: 23161705
• Methamphetamine Administration Targets Multiple Immune Subsets and Induces Phenotypic Alterations Suggestive of Immunosuppression
  PloS One. 2012  |   Pubmed ID: 23227154
• The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-associated Neurocognitive Impairment
  PloS One. 2012  |   Pubmed ID: 23049970
• Protective Role for the Disulfide Isomerase PDIA3 in Methamphetamine Neurotoxicity
  PloS One. 2012  |   Pubmed ID: 22715419
• Methamphetamine and Inflammatory Cytokines Increase Neuronal Na+/K+-ATPase Isoform 3: Relevance for HIV Associated Neurocognitive Disorders
  PloS One. 2012  |   Pubmed ID: 22662178
• Comparison of 4-plex to 8-plex ITRAQ Quantitative Measurements of Proteins in Human Plasma Samples
  Journal of Proteome Research. Jul, 2012  |   Pubmed ID: 22594965
• Commentary: Animal Models of NeuroAIDS
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jun, 2012  |   Pubmed ID: 22549136
• Translating the Brain Transcriptome in NeuroAIDS: from Non-human Primates to Humans
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jun, 2012  |   Pubmed ID: 22367717
• Proteasome Activity and Autophagosome Content in Liver Are Reciprocally Regulated by Ethanol Treatment
  Biochemical and Biophysical Research Communications. Jan, 2012  |   Pubmed ID: 22142844
• Changes in the Plasma Proteome Follows Chronic Opiate Administration in Simian Immunodeficiency Virus Infected Rhesus Macaques
  Drug and Alcohol Dependence. Jan, 2012  |   Pubmed ID: 21821369
• Upregulation of Cathepsin D in the Caudate Nucleus of Primates with Experimental Parkinsonism
  Molecular Neurodegeneration. Jul, 2011  |   Pubmed ID: 21777416
• Pulsed Stable Isotope Labeling of Amino Acids in Cell Culture Uncovers the Dynamic Interactions Between HIV-1 and the Monocyte-derived Macrophage
  Journal of Proteome Research. Jun, 2011  |   Pubmed ID: 21500866
• Short Communication: Quantitative Proteomic Plasma Profiling Reveals Activation of Host Defense to Oxidative Stress in Chronic SIV and Methamphetamine Comorbidity
  AIDS Research and Human Retroviruses. Feb, 2011  |   Pubmed ID: 20929344
• Epithelial Progenitor 1, a Novel Factor Associated with Epithelial Cell Growth and Differentiation
  Endocrine. Apr, 2010  |   Pubmed ID: 20960269
• Plasma Proteomic Analysis of Simian Immunodeficiency Virus Infection of Rhesus Macaques
  Journal of Proteome Research. Sep, 2010  |   Pubmed ID: 20677826
• Proteomic and Metabolomic Strategies to Investigate HIV-associated Neurocognitive Disorders
  Genome Medicine. Mar, 2010  |   Pubmed ID: 20353544
• Advances in the "omics" for Diagnosis, Pathogenesis, and Therapeutic Development
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2010  |   Pubmed ID: 20143174
• Quantitative Plasma Proteomic Profiling Identifies the Vitamin E Binding Protein Afamin As a Potential Pathogenic Factor in SIV Induced CNS Disease
  Journal of Proteome Research. Jan, 2010  |   Pubmed ID: 19908921
• Defining Larger Roles for "tiny" RNA Molecules: Role of MiRNAs in Neurodegeneration Research
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2010  |   Pubmed ID: 19757077
• A Coat of Many Colors: Neuroimmune Crosstalk in Human Immunodeficiency Virus Infection
  Neuron. Oct, 2009  |   Pubmed ID: 19840555
• An Integrated Systems Analysis Implicates EGR1 Downregulation in Simian Immunodeficiency Virus Encephalitis-induced Neural Dysfunction
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009  |   Pubmed ID: 19812322
• Cerebrospinal Fluid Proteomics Reveals Potential Pathogenic Changes in the Brains of SIV-infected Monkeys
  Journal of Proteome Research. May, 2009  |   Pubmed ID: 19281240
• Decreased Neuronal Autophagy in HIV Dementia: a Mechanism of Indirect Neurotoxicity
  Autophagy. Oct, 2008  |   Pubmed ID: 18772620