J. Steven Alexander

Publications

• Three-dimensional Printing of Bioactive Hernia Meshes: In vitro Proof of Principle
  Surgery. Oct, 2016  |   Pubmed ID: 27726915
• Hydrogen Sulfide Metabolism Regulates Endothelial Solute Barrier Function
  Redox Biology. Oct, 2016  |   Pubmed ID: 27552214
• From Trash to Treasure: The Untapped Potential of Endothelial Microparticles in Neurovascular Diseases
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Aug, 2016  |   Pubmed ID: 27531185
• Sulforaphane Induces Neurovascular Protection Against a Systemic Inflammatory Challenge Via Both Nrf2-dependent and Independent Pathways
  Vascular Pharmacology. Oct, 2016  |   Pubmed ID: 27401964
• Substitution with Alternative Anti-TNFα Therapy (SAVANT)-Outcomes of a Crohn's Disease Cohort Undergoing Substitution Therapy with Certolizumab
  Inflammatory Bowel Diseases. Jun, 2016  |   Pubmed ID: 27104819
• 1,25(OH)2D3 Induces Placental Vascular Smooth Muscle Cell Relaxation by Phosphorylation of Myosin Phosphatase Target Subunit 1Ser507: Potential Beneficial Effects of Vitamin D on Placental Vasculature in Humans
  Biology of Reproduction. May, 2016  |   Pubmed ID: 27075619
• "Microglial Nodules" and "newly Forming Lesions" May Be a Janus Face of Early MS Lesions; Implications from Virus-induced Demyelination, the Inside-Out Model
  BMC Neurology. Oct, 2015  |   Pubmed ID: 26499989
• Evidence for Nontraditional Lymphatics in the Choroid
  Investigative Ophthalmology & Visual Science. Feb, 2015  |   Pubmed ID: 26241180
• Dual Signals Underlying Diabetic Lymphatic Barrier Dysregulation
  Cardiovascular Research. Jul, 2015  |   Pubmed ID: 25994173
• Distinct Kinetics of Viral Replication, T Cell Infiltration, and Fibrosis in Three Phases of Myocarditis Following Theiler's Virus Infection
  Cellular Immunology. Nov-Dec, 2014  |   Pubmed ID: 25460083
• Preface of the Special Issue - "Africa"
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2014  |   Pubmed ID: 25236675
• Bioinformatics Multivariate Analysis Determined a Set of Phase-specific Biomarker Candidates in a Novel Mouse Model for Viral Myocarditis
  Circulation. Cardiovascular Genetics. Aug, 2014  |   Pubmed ID: 25031303
• Photothermolysis of Lymphatic Endothelial Cells by Gold Nanoshell-mediated Hyperthermia
  Journal of Nanoscience and Nanotechnology. Jul, 2014  |   Pubmed ID: 24758030
• Improved Wound Healing of Postischemic Cutaneous Flaps with the Use of Bone Marrow-derived Stem Cells
  The Laryngoscope. Mar, 2014  |   Pubmed ID: 23818296
• Role of Chymase in Preeclampsia
  Current Vascular Pharmacology. Sep, 2013  |   Pubmed ID: 24063379
• VEGF-A Isoform Modulation in an Preclinical TNBS Model of Ulcerative Colitis: Protective Effects of a VEGF164b Therapy
  Journal of Translational Medicine. Sep, 2013  |   Pubmed ID: 24020796
• A Recombinant Inhibitory Isoform of Vascular Endothelial Growth Factor164/165 Aggravates Ischemic Brain Damage in a Mouse Model of Focal Cerebral Ischemia
  The American Journal of Pathology. Sep, 2013  |   Pubmed ID: 23906811
• Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-mediated Transport of HDL
  Cell Metabolism. May, 2013  |   Pubmed ID: 23663736
• Does Pelvic Mesh Treated with Phosphorylcholine Improve Outcomes? An Early Experience
  European Journal of Obstetrics, Gynecology, and Reproductive Biology. Apr, 2013  |   Pubmed ID: 23280282
• Acute Carbonyl Stress Induces Occludin Glycation and Brain Microvascular Endothelial Barrier Dysfunction: Role for Glutathione-dependent Metabolism of Methylglyoxal
  Free Radical Biology & Medicine. Jan, 2013  |   Pubmed ID: 23108103
• Enhancing the Adhesion of Hematopoietic Precursor Cell Integrins with Hydrogen Peroxide Increases Recruitment Within Murine Gut
  Cell Transplantation. 2013  |   Pubmed ID: 22889470
• Immunopathological Patterns from EAE and Theiler's Virus Infection: Is Multiple Sclerosis a Homogenous 1-stage or Heterogenous 2-stage Disease?
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22633747
• Angiopoietins As Promising Biomarkers and Potential Therapeutic Targets in Brain Injury
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22633746
• Introduction: Brain Injury
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22503573
• Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy
  Neurological Research. Oct, 2012  |   Pubmed ID: 22828184
• Plasma Ubiquitin-proteasome System Profile in Patients with Multiple Sclerosis: Correlation with Clinical Features, Neuroimaging, and Treatment with Interferon-beta-1b
  Neurological Research. Jul, 2012  |   Pubmed ID: 22709658
• Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
  International Journal of Cell Biology. 2012  |   Pubmed ID: 22505936
• Rapamycin Inhibits Lymphatic Endothelial Cell Tube Formation by Downregulating Vascular Endothelial Growth Factor Receptor 3 Protein Expression
  Neoplasia (New York, N.Y.). Mar, 2012  |   Pubmed ID: 22496622
• Interferon-beta-1b Protects Against Multiple Sclerosis-induced Endothelial Cells Apoptosis
  Frontiers in Bioscience (Elite Edition). Jan, 2012  |   Pubmed ID: 22201961
• Gliovascular and Cytokine Interactions Modulate Brain Endothelial Barrier in Vitro
  Journal of Neuroinflammation. Nov, 2011  |   Pubmed ID: 22112345
• Synergistic Effect of Resveratrol and Quercetin Released from Drug-eluting Polymer Coatings for Endovascular Devices
  Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2011  |   Pubmed ID: 21948767
• Cryptotanshinone Inhibits Lymphatic Endothelial Cell Tube Formation by Suppressing VEGFR-3/ERK and Small GTPase Pathways
  Cancer Prevention Research (Philadelphia, Pa.). Dec, 2011  |   Pubmed ID: 21881029
• Analysis of Endothelial Barrier Function in Vitro
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21874457
• Complement in Neurobiology
  Frontiers in Bioscience (Landmark Edition). Jun, 2011  |   Pubmed ID: 21622213
• The Effects of High Dose Interferon-β1a on Plasma Microparticles: Correlation with MRI Parameters
  Journal of Neuroinflammation. May, 2011  |   Pubmed ID: 21554694
• Role of the Endothelium in Inflammatory Bowel Diseases
  World Journal of Gastroenterology. Feb, 2011  |   Pubmed ID: 21350707
• Selectin-mediated Recruitment of Bone Marrow Stromal Cells in the Postischemic Cerebral Microvasculature
  Stroke; a Journal of Cerebral Circulation. Mar, 2011  |   Pubmed ID: 21257828
• Multiple Sclerosis and Cerebral Endothelial Dysfunction: Mechanisms
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2011  |   Pubmed ID: 20663648
• Murine RVEGF164b, an Inhibitory VEGF Reduces VEGF-A-dependent Endothelial Proliferation and Barrier Dysfunction
  Microcirculation (New York, N.Y. : 1994). Oct, 2010  |   Pubmed ID: 21040119
• Emerging Roles of Lymphatics in Inflammatory Bowel Disease
  Annals of the New York Academy of Sciences. Oct, 2010  |   Pubmed ID: 20961310
• VEGF₁₆₄ Differentially Regulates Neutrophil and T Cell Adhesion Through ItgaL- and ItgaM-dependent Mechanisms
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2010  |   Pubmed ID: 20884890
• Analysis of in Vitro Transfection by Sonoporation Using Cationic and Neutral Microbubbles
  Ultrasound in Medicine & Biology. Nov, 2010  |   Pubmed ID: 20800945
• Elevated Plasma Chymotrypsin-like Protease (chymase) Activity in Women with Preeclampsia
  Hypertension in Pregnancy. 2010  |   Pubmed ID: 20670150
• Induction of Neuro-protective/regenerative Genes in Stem Cells Infiltrating Post-ischemic Brain Tissue
  Experimental & Translational Stroke Medicine. May, 2010  |   Pubmed ID: 20509949
• Alemtuzumab and Multiple Sclerosis: Therapeutic Application
  Expert Opinion on Biological Therapy. Mar, 2010  |   Pubmed ID: 20095876
• Editorial: Lymphatic Vessel Functions in Health and Disease
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2010  |   Pubmed ID: 20005084
• Angiopoietin-2 in Experimental Colitis
  Inflammatory Bowel Diseases. Jun, 2010  |   Pubmed ID: 19902545
• Potential Roles of Cell-derived Microparticles in Ischemic Brain Disease
  Neurological Research. Oct, 2009  |   Pubmed ID: 19723448
• Chymotrypsin-like Protease (chymase) Mediates Endothelial Activation by Factors Derived from Preeclamptic Placentas
  Reproductive Sciences (Thousand Oaks, Calif.). Sep, 2009  |   Pubmed ID: 19494363
• Placenta-derived Chymotrypsin-like Protease (CLP) Disturbs Endothelial Junctional Structure in Preeclampsia
  Reproductive Sciences (Thousand Oaks, Calif.). May, 2009  |   Pubmed ID: 19126871
• Isotope Tracing Enhancement of Chemiluminescence Assays for Nitric Oxide Research
  Biological Chemistry. Feb, 2009  |   Pubmed ID: 19040352
• Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Glutamate/MK-801: Significance in Ischemic Stroke Injury
  Journal of Molecular Neuroscience : MN. Jun, 2009  |   Pubmed ID: 18843451
• Evidence of Platelet Activation in Multiple Sclerosis
  Journal of Neuroinflammation. Jun, 2008  |   Pubmed ID: 18588683
• NeuroAIDS: Characteristics and Diagnosis of the Neurological Complications of AIDS
  Molecular Diagnosis & Therapy. 2008  |   Pubmed ID: 18288880
• Combination Therapy with Interferon Beta-1a and Doxycycline in Multiple Sclerosis: an Open-label Trial
  Archives of Neurology. Feb, 2008  |   Pubmed ID: 18071030
• Clinical and Neuroimaging Correlates of Antiphospholipid Antibodies in Multiple Sclerosis: a Preliminary Study
  BMC Neurology. Oct, 2007  |   Pubmed ID: 17945023
• Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Multiple Sclerosis Serum and IFNbeta-1b
  Journal of Molecular Neuroscience : MN. 2007  |   Pubmed ID: 17873362
• Inflammatory Cytokines Induce MAdCAM-1 in Murine Hepatic Endothelial Cells and Mediate Alpha-4 Beta-7 Integrin Dependent Lymphocyte Endothelial Adhesion in Vitro
  BMC Physiology. Sep, 2007  |   Pubmed ID: 17868448
• HIV Antiretroviral Drug Combination Induces Endothelial Mitochondrial Dysfunction and Reactive Oxygen Species Production, but Not Apoptosis
  Toxicology and Applied Pharmacology. Oct, 2007  |   Pubmed ID: 17669453
• Platelet-associated NAD(P)H Oxidase Contributes to the Thrombogenic Phenotype Induced by Hypercholesterolemia
  Free Radical Biology & Medicine. Jul, 2007  |   Pubmed ID: 17561090
• Evolving Therapies for Multiple Sclerosis
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531859
• Cell-derived Microparticles and Exosomes in Neuroinflammatory Disorders
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531844
• The Destructive Alliance: Interactions of Leukocytes, Cerebral Endothelial Cells, and the Immune Cascade in Pathogenesis of Multiple Sclerosis
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531835
• CD40-CD40 Ligand Mediates the Recruitment of Leukocytes and Platelets in the Inflamed Murine Colon
  Gastroenterology. Mar, 2007  |   Pubmed ID: 17324402
• Multiple Sclerosis As a Vascular Disease
  Neurological Research. Apr, 2006  |   Pubmed ID: 16687046
• Expression of Lymphatic Vascular Endothelial Hyaluronan Receptor-1 (LYVE-1) in the Human Placenta
  Lymphatic Research and Biology. 2006  |   Pubmed ID: 16569201
• Insulin Prevents Oxidant-induced Endothelial Cell Barrier Dysfunction Via Nitric Oxide-dependent Pathway
  Surgery. Jan, 2006  |   Pubmed ID: 16364721
• VEGF-A Stimulation of Leukocyte Adhesion to Colonic Microvascular Endothelium: Implications for Inflammatory Bowel Disease
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2006  |   Pubmed ID: 16293653
• Apolipoprotein A-IV Attenuates Oxidant-induced Apoptosis in Mitotic Competent, Undifferentiated Cells by Modulating Intracellular Glutathione Redox Balance
  American Journal of Physiology. Cell Physiology. Jan, 2006  |   Pubmed ID: 16120654
• Effects of Peroxynitrite and Superoxide Radicals on Endothelial Monolayer Permeability: Potential Role of Peroxynitrite in Preeclampsia
  Journal of the Society for Gynecologic Investigation. Dec, 2005  |   Pubmed ID: 16325748
• The Role of Alpha-4 Integrin in the Aetiology of Multiple Sclerosis: Current Knowledge and Therapeutic Implications
  CNS Drugs. 2005  |   Pubmed ID: 16268663
• Reversal of Experimental Colitis Disease Activity in Mice Following Administration of an Adenoviral IL-10 Vector
  Journal of Inflammation (London, England). Oct, 2005  |   Pubmed ID: 16259632
• DSS-induced Colitis is Exacerbated in STAT-6 Knockout Mice
  Inflammatory Bowel Diseases. Oct, 2005  |   Pubmed ID: 16189417
• Troglitazone, a PPAR-gamma Activator Prevents Endothelial Cell Adhesion Molecule Expression and Lymphocyte Adhesion Mediated by TNF-alpha
  BMC Physiology. Feb, 2005  |   Pubmed ID: 15694007
• Near-infrared Spectroscopy: a Tool to Monitor Cerebral Hemodynamic and Metabolic Changes After Cardiac Arrest in Rats
  Resuscitation. Nov, 2004  |   Pubmed ID: 15531074
• Mmp-9 Deficiency Enhances Collagenase-induced Intracerebral Hemorrhage and Brain Injury in Mutant Mice
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2004  |   Pubmed ID: 15529013
• Cerebral Cortical Aquaporin-4 Expression in Brain Edema Following Cardiac Arrest in Rats
  Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Oct, 2004  |   Pubmed ID: 15466140
• HIV-associated Dementia, Alzheimer's Disease, Multiple Sclerosis, and Schizophrenia: Gene Expression Review
  Journal of the Neurological Sciences. Sep, 2004  |   Pubmed ID: 15450765
• Pathogenesis of Brain and Spinal Cord Atrophy in Multiple Sclerosis
  Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. Jul, 2004  |   Pubmed ID: 15228754
• Effect of Ifenprodil, a Polyamine Site NMDA Receptor Antagonist, on Brain Edema Formation Following Asphyxial Cardiac Arrest in Rats
  Resuscitation. May, 2004  |   Pubmed ID: 15135198
• Human Cytomegalovirus Induces Monocyte Differentiation and Migration As a Strategy for Dissemination and Persistence
  Journal of Virology. May, 2004  |   Pubmed ID: 15078925
• CYP450 Dietary Inhibitors Attenuate TNF-alpha-stimulated Endothelial Molecule Expression and Leukocyte Adhesion
  American Journal of Physiology. Cell Physiology. Apr, 2004  |   Pubmed ID: 15001427
• Stereotactic Radiosurgery Using the Leksell Gamma Knife: Current Trends and Future Directives
  Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2004  |   Pubmed ID: 14766419
• Role of Prostaglandins in Maintaining Gastric Mucus-cell Permeability Against Acid Exposure
  The Journal of Laboratory and Clinical Medicine. Jan, 2004  |   Pubmed ID: 14749685
• Increased Disease Activity in ENOS-deficient Mice in Experimental Colitis
  Free Radical Biology & Medicine. Dec, 2003  |   Pubmed ID: 14680690
• Blood-brain Barrier Disruption in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2003  |   Pubmed ID: 14664465
• Tight Junction Peptide Antagonists Enhance Neutrophil Trans-endothelial Chemotaxis
  Life Sciences. Aug, 2003  |   Pubmed ID: 12875904
• Gamma Knife Irradiation Increases Cerebral Endothelial Expression of Intercellular Adhesion Molecule 1 and E-selectin
  Neurosurgery. Jul, 2003  |   Pubmed ID: 12823884
• Serum from Patients with Multiple Sclerosis Downregulates Occludin and VE-cadherin Expression in Cultured Endothelial Cells
  Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2003  |   Pubmed ID: 12814168
• Randomized, Placebo-controlled, Double Blind, Crossover Design Trial of the Efficacy and Safety of Zestra for Women in Women with and Without Female Sexual Arousal Disorder
  Journal of Sex & Marital Therapy. 2003  |   Pubmed ID: 12735087
• The 3-hydroxy-3-methylglutaryl-CoA Reductase Inhibitor Pravastatin Reduces Disease Activity and Inflammation in Dextran-sulfate Induced Colitis
  The Journal of Pharmacology and Experimental Therapeutics. Apr, 2003  |   Pubmed ID: 12649355
• Transfection of IL-10 Expression Vectors into Endothelial Cultures Attenuates Alpha4beta7-dependent Lymphocyte Adhesion Mediated by MAdCAM-1
  BMC Gastroenterology. Feb, 2003  |   Pubmed ID: 12625840
• Is the Gastric Epithelial Barrier Regulated by Cadherin Recruitment?
  European Journal of Gastroenterology & Hepatology. Dec, 2002  |   Pubmed ID: 12468947
• Devic Disease: Clinical Course, Pathophysiology, and Management
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Oct, 2002  |   Pubmed ID: 12385963
• Identification of an Occludin Cell Adhesion Recognition Sequence
  Inflammation. Aug, 2002  |   Pubmed ID: 12184633
• Extravascular Transport of Fluorescently Labeled Albumins in the Rat Mesentery
  Microcirculation (New York, N.Y. : 1994). Jul, 2002  |   Pubmed ID: 12080415
• Endothelial Junctional Protein Redistribution and Increased Monolayer Permeability in Human Umbilical Vein Endothelial Cells Isolated During Preeclampsia
  American Journal of Obstetrics and Gynecology. Feb, 2002  |   Pubmed ID: 11854638
• Mild Hypothermia Induced Before Cardiac Arrest Reduces Brain Edema Formation in Rats
  Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Feb, 2002  |   Pubmed ID: 11825833