Jacob H. Hanna Department of Molecular Genetics Weizmann Institute of Science Biography Publications Institution JoVE Articles Jacob H. Hanna has not added a biography. If you are Jacob H. Hanna and would like to personalize this page please email our Author Liaison for assistance. Publications Mechanism of Noncoding RNA-associated N-methyladenosine Recognition by an RNA Processing Complex During IgH DNA Recombination Molecular Cell. Oct, 2021 | Pubmed ID: 34450044 The Germinal Center Reaction Depends on RNA Methylation and Divergent Functions of Specific Methyl Readers The Journal of Experimental Medicine. Oct, 2021 | Pubmed ID: 34402854 Modeling Genetic Epileptic Encephalopathies Using Brain Organoids EMBO Molecular Medicine. Aug, 2021 | Pubmed ID: 34268881 Principles of Signaling Pathway Modulation for Enhancing Human Naive Pluripotency Induction Cell Stem Cell. 09, 2021 | Pubmed ID: 33915080 Ex Utero Mouse Embryogenesis from Pre-gastrulation to Late Organogenesis Nature. 05, 2021 | Pubmed ID: 33731940 Production and Analysis of Human Primordial Germ Cell-Like Cells Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 32852762 Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis Molecular Cell. 12, 2020 | Pubmed ID: 33217318 Context-dependent Functional Compensation Between Ythdf MA Reader Proteins Genes & Development. 10, 2020 | Pubmed ID: 32943573 β-Catenin Safeguards the Ground State of Mousepluripotency by Strengthening the Robustness of the Transcriptional Apparatus Science Advances. Jul, 2020 | Pubmed ID: 32832621 Generation of Human Endothelium in Pig Embryos Deficient in ETV2 Nature Biotechnology. 03, 2020 | Pubmed ID: 32094659 Deciphering the "mA Code" Via Antibody-Independent Quantitative Profiling Cell. 07, 2019 | Pubmed ID: 31257032 Stage-specific Requirement for Mettl3-dependent MA MRNA Methylation During Haematopoietic Stem Cell Differentiation Nature Cell Biology. 06, 2019 | Pubmed ID: 31061465 Universally Non-immunogenic IPSCs Nature Biomedical Engineering. 05, 2019 | Pubmed ID: 31036889 Stem Cell-Derived Human Gametes: The Public Engagement Imperative Trends in Molecular Medicine. 03, 2019 | Pubmed ID: 30738627 Publisher Correction: M6A Modification Controls the Innate Immune Response to Infection by Targeting Type I Interferons Nature Immunology. 02, 2019 | Pubmed ID: 30635652 The N-Methyladenosine MRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy Circulation. 01, 2019 | Pubmed ID: 30586742 MA Modification Controls the Innate Immune Response to Infection by Targeting Type I Interferons Nature Immunology. 02, 2019 | Pubmed ID: 30559377 Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules Cell Stem Cell. Dec, 2018 | Pubmed ID: 30554962 MTCH2-mediated Mitochondrial Fusion Drives Exit from Naïve Pluripotency in Embryonic Stem Cells Nature Communications. 12, 2018 | Pubmed ID: 30510213 Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency Cell Stem Cell. Sep, 2018 | Pubmed ID: 30122475 The Role of MA/m-RNA Methylation in Stress Response Regulation Neuron. Jul, 2018 | Pubmed ID: 30048615 Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies Immunity. May, 2018 | Pubmed ID: 29768178 Human Brain Organoids on a Chip Reveal the Physics of Folding Nature Physics. May, 2018 | Pubmed ID: 29760764 MA Deposition: a Boost from TGFβ Cell Research. May, 2018 | Pubmed ID: 29679051 RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells Stem Cell Reports. 03, 2018 | Pubmed ID: 29456180 NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis Immunity. 01, 2018 | Pubmed ID: 29329948 Relevance of IPSC-derived Human PGC-like Cells at the Surface of Embryoid Bodies to Prechemotaxis Migrating PGCs Proceedings of the National Academy of Sciences of the United States of America. 11, 2017 | Pubmed ID: 29087313 OCT4 Impedes Cell Fate Redirection by the Melanocyte Lineage Master Regulator MITF in Mouse ESCs Nature Communications. Oct, 2017 | Pubmed ID: 29044103 Increased NK Cell Immunity in a Transgenic Mouse Model of NKp46 Overexpression Scientific Reports. 10, 2017 | Pubmed ID: 29026144 A Multiplexed Screening Method for Pluripotency Stem Cell Research. 08, 2017 | Pubmed ID: 28756340 MA MRNA Modifications Are Deposited in Nascent Pre-mRNA and Are Not Required for Splicing but Do Specify Cytoplasmic Turnover Genes & Development. 05, 2017 | Pubmed ID: 28637692 Transcriptional Programs That Control Expression of the Autoimmune Regulator Gene Aire Nature Immunology. 02, 2017 | Pubmed ID: 27941786 Co-ChIP Enables Genome-wide Mapping of Histone Mark Co-occurrence at Single-molecule Resolution Nature Biotechnology. 09, 2016 | Pubmed ID: 27454738 Dynamic Stem Cell States: Naive to Primed Pluripotency in Rodents and Humans Nature Reviews. Molecular Cell Biology. Mar, 2016 | Pubmed ID: 26860365 Evolutionary Analysis Across Mammals Reveals Distinct Classes of Long Non-coding RNAs Genome Biology. Feb, 2016 | Pubmed ID: 26838501 An Essential Role for UTX in Resolution and Activation of Bivalent Promoters Nucleic Acids Research. 05, 2016 | Pubmed ID: 26762983 Failure to Replicate the STAP Cell Phenomenon Nature. Sep, 2015 | Pubmed ID: 26399835 Establishing the Human Naïve Pluripotent State Current Opinion in Genetics & Development. Oct, 2015 | Pubmed ID: 26291026 Transient Acquisition of Pluripotency During Somatic Cell Transdifferentiation with IPSC Reprogramming Factors Nature Biotechnology. Jul, 2015 | Pubmed ID: 26098448 CD24 Tracks Divergent Pluripotent States in Mouse and Human Cells Nature Communications. Jun, 2015 | Pubmed ID: 26076835 Stem Cells. M6A MRNA Methylation Facilitates Resolution of Naïve Pluripotency Toward Differentiation Science (New York, N.Y.). Feb, 2015 | Pubmed ID: 25569111 SOX17 is a Critical Specifier of Human Primordial Germ Cell Fate Cell. Jan, 2015 | Pubmed ID: 25543152 Hijacked by an Oocyte: Hierarchical Molecular Changes in Somatic Cell Nuclear Transfer Molecular Cell. Aug, 2014 | Pubmed ID: 25148360 Stem Cells: The Quest for the Perfect Reprogrammed Cell Nature. Jul, 2014 | Pubmed ID: 25008516 Lucky IPSCs Genome Biology. Mar, 2014 | Pubmed ID: 25002192 Passage Number is a Major Contributor to Genomic Structural Variations in Mouse IPSCs Stem Cells (Dayton, Ohio). Oct, 2014 | Pubmed ID: 24965231 Derivation of Novel Human Ground State Naive Pluripotent Stem Cells Nature. Dec, 2013 | Pubmed ID: 24172903 Deterministic Direct Reprogramming of Somatic Cells to Pluripotency Nature. Oct, 2013 | Pubmed ID: 24048479 The Expression of the Beta Cell-derived Autoimmune Ligand for the Killer Receptor Nkp46 is Attenuated in Type 2 Diabetes PloS One. 2013 | Pubmed ID: 24009765 Oct4 Shuffles Sox Partners to Direct Cell Fate The EMBO Journal. Apr, 2013 | Pubmed ID: 23474893 The H3K27 Demethylase Utx Regulates Somatic and Germ Cell Epigenetic Reprogramming Nature. Aug, 2012 | Pubmed ID: 22801502 خارج الرحم زراعة أجنة الفئران من ما قبل المعدة إلى التكوين العضوي المتقدم Alejandro Aguilera-Castrejon1, Jacob H. Hanna1 1Department of Molecular Genetics, Weizmann Institute of Science JoVE 63160 Developmental Biology جيل من البشرية البدائية الخلية الجرثومية مثل الخلايا على سطح الهيئات امبريويد من بلوريبوتينسي جاهزة للانفجار الناجم عن الخلايا الجذعية Pluripotent Shino Mitsunaga1, Keiko Shioda1, Kurt J. Isselbacher1, Jacob H. Hanna2, Toshi Shioda1 1Center for Cancer Research, Massachusetts General Hospital, 2Department of Molecular Genetics, Weizmann Institute of Science JoVE 58297 Developmental Biology
خارج الرحم زراعة أجنة الفئران من ما قبل المعدة إلى التكوين العضوي المتقدم Alejandro Aguilera-Castrejon1, Jacob H. Hanna1 1Department of Molecular Genetics, Weizmann Institute of Science JoVE 63160 Developmental Biology
جيل من البشرية البدائية الخلية الجرثومية مثل الخلايا على سطح الهيئات امبريويد من بلوريبوتينسي جاهزة للانفجار الناجم عن الخلايا الجذعية Pluripotent Shino Mitsunaga1, Keiko Shioda1, Kurt J. Isselbacher1, Jacob H. Hanna2, Toshi Shioda1 1Center for Cancer Research, Massachusetts General Hospital, 2Department of Molecular Genetics, Weizmann Institute of Science JoVE 58297 Developmental Biology
