James A. Thomson

Publications

• Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Mar, 2012  |   Pubmed ID: 22213079
• Thermal Stability of FGF Protein is a Determinant Factor in Regulating Self-Renewal, Differentiation and Reprogramming in Human Pluripotent Stem Cells
  Stem Cells (Dayton, Ohio). Dec, 2011  |   Pubmed ID: 22213113
• Proteomics and Pluripotency
  Critical Reviews in Biochemistry and Molecular Biology. Dec, 2011  |   Pubmed ID: 21999516
• Proteomic and Phosphoproteomic Comparison of Human ES and IPS Cells
  Nature Methods. 2011  |   Pubmed ID: 21983960
• High Purity Human-induced Pluripotent Stem Cell-derived Cardiomyocytes: Electrophysiological Properties of Action Potentials and Ionic Currents
  American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2011  |   Pubmed ID: 21890694
• Dynamic Chromatin States in Human ES Cells Reveal Potential Regulatory Sequences and Genes Involved in Pluripotency
  Cell Research. Oct, 2011  |   Pubmed ID: 21876557
• Human Lymphoblastoid B-cell Lines Reprogrammed to EBV-free Induced Pluripotent Stem Cells
  Blood. Aug, 2011  |   Pubmed ID: 21708888
• Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment
  Stem Cells (Dayton, Ohio). Aug, 2011  |   Pubmed ID: 21678528
• TF-Cluster: a Pipeline for Identifying Functionally Coordinated Transcription Factors Via Network Decomposition of the Shared Coexpression Connectivity Matrix (SCCM)
  BMC Systems Biology. 2011  |   Pubmed ID: 21496241
• Chemically Defined Conditions for Human IPSC Derivation and Culture
  Nature Methods. May, 2011  |   Pubmed ID: 21478862
• Genetic Correction and Analysis of Induced Pluripotent Stem Cells from a Patient with Gyrate Atrophy
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011  |   Pubmed ID: 21464322
• Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells
  Stem Cells and Development. Sep, 2011  |   Pubmed ID: 21434814
• Somatic Coding Mutations in Human Induced Pluripotent Stem Cells
  Nature. Mar, 2011  |   Pubmed ID: 21368825
• FGF2 Sustains NANOG and Switches the Outcome of BMP4-induced Human Embryonic Stem Cell Differentiation
  Cell Stem Cell. Mar, 2011  |   Pubmed ID: 21362572
• Efficient Generation of Transgene-free Induced Pluripotent Stem Cells from Normal and Neoplastic Bone Marrow and Cord Blood Mononuclear Cells
  Blood. Apr, 2011  |   Pubmed ID: 21296996
• Hotspots of Aberrant Epigenomic Reprogramming in Human Induced Pluripotent Stem Cells
  Nature. Mar, 2011  |   Pubmed ID: 21289626
• A Mesoderm-derived Precursor for Mesenchymal Stem and Endothelial Cells
  Cell Stem Cell. Dec, 2010  |   Pubmed ID: 21112566
• The NIH Roadmap Epigenomics Mapping Consortium
  Nature Biotechnology. Oct, 2010  |   Pubmed ID: 20944595
• The Social Cognitive Determinants of Offending Drivers' Speeding Behaviour
  Accident; Analysis and Prevention. Nov, 2010  |   Pubmed ID: 20728608
• Quantitative Selection of DNA Aptamers Through Microfluidic Selection and High-throughput Sequencing
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010  |   Pubmed ID: 20705898
• Actin-myosin Contractility is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells
  Cell Stem Cell. Aug, 2010  |   Pubmed ID: 20682449
• Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells
  Cell Stem Cell. May, 2010  |   Pubmed ID: 20452322
• No Evidence for Clonal Selection Due to Lentiviral Integration Sites in Human Induced Pluripotent Stem Cells
  Stem Cells (Dayton, Ohio). Apr, 2010  |   Pubmed ID: 20166152
• Neural Differentiation of Human Induced Pluripotent Stem Cells Follows Developmental Principles but with Variable Potency
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20160098
• RNA-Seq Gene Expression Estimation with Read Mapping Uncertainty
  Bioinformatics (Oxford, England). Feb, 2010  |   Pubmed ID: 20022975
• The Microwell Control of Embryoid Body Size in Order to Regulate Cardiac Differentiation of Human Embryonic Stem Cells
  Biomaterials. Mar, 2010  |   Pubmed ID: 19945747
• Human DNA Methylomes at Base Resolution Show Widespread Epigenomic Differences
  Nature. Nov, 2009  |   Pubmed ID: 19829295
• MicroRNA 92b Controls the G1/S Checkpoint Gene P57 in Human Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Jul, 2009  |   Pubmed ID: 19544458
• MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells
  Cell. May, 2009  |   Pubmed ID: 19409607
• ProbeMatch: Rapid Alignment of Oligonucleotides to Genome Allowing Both Gaps and Mismatches
  Bioinformatics (Oxford, England). Jun, 2009  |   Pubmed ID: 19351619
• Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
  Science (New York, N.Y.). May, 2009  |   Pubmed ID: 19325077
• Histone Modifications at Human Enhancers Reflect Global Cell-type-specific Gene Expression
  Nature. May, 2009  |   Pubmed ID: 19295514
• Functional Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells
  Circulation Research. Feb, 2009  |   Pubmed ID: 19213953
• Human Embryonic Stem Cell Phosphoproteome Revealed by Electron Transfer Dissociation Tandem Mass Spectrometry
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009  |   Pubmed ID: 19144917
• Induced Pluripotent Stem Cells from a Spinal Muscular Atrophy Patient
  Nature. Jan, 2009  |   Pubmed ID: 19098894
• Secreted Proteoglycans Directly Mediate Human Embryonic Stem Cell-basic Fibroblast Growth Factor 2 Interactions Critical for Proliferation
  Stem Cells (Dayton, Ohio). Dec, 2008  |   Pubmed ID: 18802039
• Cell Type-specific DNA Methylation Patterns in the Human Breast
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008  |   Pubmed ID: 18780791
• NANOG is a Direct Target of TGFbeta/activin-mediated SMAD Signaling in Human ESCs
  Cell Stem Cell. Aug, 2008  |   Pubmed ID: 18682241
• Pluripotent Stem Cell Lines
  Genes & Development. Aug, 2008  |   Pubmed ID: 18676805
• Optical Mapping Discerns Genome Wide DNA Methylation Profiles
  BMC Molecular Biology. 2008  |   Pubmed ID: 18667073
• Ronin is Essential for Embryogenesis and the Pluripotency of Mouse Embryonic Stem Cells
  Cell. Jun, 2008  |   Pubmed ID: 18585351
• Caspase Activity Mediates the Differentiation of Embryonic Stem Cells
  Cell Stem Cell. Jun, 2008  |   Pubmed ID: 18522852
• A Study of the Relationships Between Oligonucleotide Properties and Hybridization Signal Intensities from NimbleGen Microarray Datasets
  Nucleic Acids Research. May, 2008  |   Pubmed ID: 18385155
• Mass Spectrometry Identifies and Quantifies 74 Unique Histone H4 Isoforms in Differentiating Human Embryonic Stem Cells
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008  |   Pubmed ID: 18326628
• Dielectrophoretic Separation of Platelets from Diluted Whole Blood in Microfluidic Channels
  Electrophoresis. Mar, 2008  |   Pubmed ID: 18288670
• Steady-state and Pre-steady-state Kinetic Evaluation of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CLpro Cysteine Protease: Development of an Ion-pair Model for Catalysis
  Biochemistry. Feb, 2008  |   Pubmed ID: 18237196
• Defined, Feeder-independent Medium for Human Embryonic Stem Cell Culture
  Current Protocols in Stem Cell Biology. Sep, 2007  |   Pubmed ID: 18785163
• Whole-genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells
  Cell Stem Cell. Sep, 2007  |   Pubmed ID: 18371364
• Conserved Regulation of MAP Kinase Expression by PUF RNA-binding Proteins
  PLoS Genetics. Dec, 2007  |   Pubmed ID: 18166083
• Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
  Science (New York, N.Y.). Dec, 2007  |   Pubmed ID: 18029452
• A Microarray Analysis of the Emergence of Embryonic Definitive Hematopoiesis
  Experimental Hematology. Sep, 2007  |   Pubmed ID: 17761287
• LongSAGE Profiling of Nine Human Embryonic Stem Cell Lines
  Genome Biology. 2007  |   Pubmed ID: 17570852
• Defined Substrates for Human Embryonic Stem Cell Growth Identified from Surface Arrays
  ACS Chemical Biology. May, 2007  |   Pubmed ID: 17480050
• Differential Requirements for Hematopoietic Commitment Between Human and Rhesus Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Feb, 2007  |   Pubmed ID: 17284653
• Nanog and Transcriptional Networks in Embryonic Stem Cell Pluripotency
  Cell Research. Jan, 2007  |   Pubmed ID: 17211451
• Microarray Analysis of Stem Cells and Differentiation
  Methods in Enzymology. 2006  |   Pubmed ID: 17161699
• A Severe De Novo Methylation of Episomal Vectors by Human ES Cells
  Biochemical and Biophysical Research Communications. Nov, 2006  |   Pubmed ID: 16973130
• Feeder-independent Culture of Human Embryonic Stem Cells
  Nature Methods. Aug, 2006  |   Pubmed ID: 16862139
• Leukosialin (CD43) Defines Hematopoietic Progenitors in Human Embryonic Stem Cell Differentiation Cultures
  Blood. Sep, 2006  |   Pubmed ID: 16757688
• Directed Differentiation of Human Embryonic Stem Cells into Functional Dendritic Cells Through the Myeloid Pathway
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2006  |   Pubmed ID: 16493050
• Derivation of Human Embryonic Stem Cells in Defined Conditions
  Nature Biotechnology. Feb, 2006  |   Pubmed ID: 16388305
• Basic Fibroblast Growth Factor Support of Human Embryonic Stem Cell Self-renewal
  Stem Cells (Dayton, Ohio). Mar, 2006  |   Pubmed ID: 16282444
• Human Embryonic Stem Cell-derived Hematopoietic Cells Are Capable of Engrafting Primary As Well As Secondary Fetal Sheep Recipients
  Blood. Mar, 2006  |   Pubmed ID: 16278307
• Human Embryonic Stem Cells Reprogram Myeloid Precursors Following Cell-cell Fusion
  Stem Cells (Dayton, Ohio). Jan, 2006  |   Pubmed ID: 16210403
• Influence of Virtual Reality Training on the Roadside Crossing Judgments of Child Pedestrians
  Journal of Experimental Psychology. Applied. Sep, 2005  |   Pubmed ID: 16221036
• Human ERas Gene Has an Upstream Premature Polyadenylation Signal That Results in a Truncated, Noncoding Transcript
  Stem Cells (Dayton, Ohio). Nov-Dec, 2005  |   Pubmed ID: 16081664
• The Effects of Adult Guidance and Peer Discussion on the Development of Children's Representations: Evidence from the Training of Pedestrian Skills
  British Journal of Psychology (London, England : 1953). May, 2005  |   Pubmed ID: 15969830
• Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Jun-Jul, 2005  |   Pubmed ID: 15917474
• Basic FGF and Suppression of BMP Signaling Sustain Undifferentiated Proliferation of Human ES Cells
  Nature Methods. Mar, 2005  |   Pubmed ID: 15782187
• Differentiation of Human Embryonic Stem Cells Occurs Through Symmetric Cell Division
  Stem Cells (Dayton, Ohio). Feb, 2005  |   Pubmed ID: 15671139
• A Germ Cell Origin of Embryonic Stem Cells?
  Development (Cambridge, England). Jan, 2005  |   Pubmed ID: 15623802
• Human Embryonic Stem Cell-derived CD34+ Cells: Efficient Production in the Coculture with OP9 Stromal Cells and Analysis of Lymphohematopoietic Potential
  Blood. Jan, 2005  |   Pubmed ID: 15374881
• Crystal Structure of Human ABAD/HSD10 with a Bound Inhibitor: Implications for Design of Alzheimer's Disease Therapeutics
  Journal of Molecular Biology. Sep, 2004  |   Pubmed ID: 15342248
• Arrays for the Combinatorial Exploration of Cell Adhesion
  Journal of the American Chemical Society. Sep, 2004  |   Pubmed ID: 15339142
• Trophoblast Differentiation in Embryoid Bodies Derived from Human Embryonic Stem Cells
  Endocrinology. Apr, 2004  |   Pubmed ID: 14684604
• Recurrent Gain of Chromosomes 17q and 12 in Cultured Human Embryonic Stem Cells
  Nature Biotechnology. Jan, 2004  |   Pubmed ID: 14661028
• Functional Endothelial Cells Derived from Rhesus Monkey Embryonic Stem Cells
  Blood. Feb, 2004  |   Pubmed ID: 14563647
• Gene Expression Patterns in Human Embryonic Stem Cells and Human Pluripotent Germ Cell Tumors
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003  |   Pubmed ID: 14595015
• Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme
  Journal of Virology. Jul, 2003  |   Pubmed ID: 12805457
• Human Embryonic Stem Cells Develop into Multiple Types of Cardiac Myocytes: Action Potential Characterization
  Circulation Research. Jul, 2003  |   Pubmed ID: 12791707
• Homologous Recombination in Human Embryonic Stem Cells
  Nature Biotechnology. Mar, 2003  |   Pubmed ID: 12577066
• High-level Sustained Transgene Expression in Human Embryonic Stem Cells Using Lentiviral Vectors
  Stem Cells (Dayton, Ohio). 2003  |   Pubmed ID: 12529558
• BMP4 Initiates Human Embryonic Stem Cell Differentiation to Trophoblast
  Nature Biotechnology. Dec, 2002  |   Pubmed ID: 12426580
• Surface Antigens of Human Embryonic Stem Cells: Changes Upon Differentiation in Culture
  Journal of Anatomy. Mar, 2002  |   Pubmed ID: 12033729
• Efficient Method for Expressing Transgenes in Nonhuman Primate Embryos Using a Stable Episomal Vector
  Molecular Reproduction and Development. May, 2002  |   Pubmed ID: 11933162
• On-Line Updating of Spatial Information Druing Locomotion Without Vision
  Journal of Motor Behavior. Mar, 1999  |   Pubmed ID: 11177618