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Articles by James I. Andorko in JoVE
Intra-lymph Node Injection of Biodegradable Polymer Particles James I. Andorko*1, Lisa H. Tostanoski*1, Eduardo Solano1, Maryam Mukhamedova1, Christopher M. Jewell1 1Fischell Department of Bioengineering, University of Maryland, College Park Lymph nodes are the immunological tissues that orchestrate immune response and are a critical target for vaccines. Biomaterials have been employed to better target lymph nodes and to control delivery of antigens or adjuvants. This paper describes a technique combining these ideas to inject biocompatible polymer particles into lymph nodes.