James Fraser Department of Veterinary and Biomedical Sciences The Pennsylvania State University Biography Publications Institution JoVE Articles James Fraser has not added a biography. If you are James Fraser and would like to personalize this page please email our Author Liaison for assistance. Publications Calcium-dependent Nedd4-2 Upregulation Mediates Degradation of the Cardiac Sodium Channel Nav1.5: Implications for Heart Failure Acta Physiologica (Oxford, England). Mar, 2017 | Pubmed ID: 28296171 Complex Multi-enhancer Contacts Captured by Genome Architecture Mapping Nature. Mar, 2017 | Pubmed ID: 28273065 QUESTION 2: Does Prophylactic Nystatin Prevent Invasive Fungal Infections in Immunocompetent Critically Ill Children on Broad-spectrum Antibiotics? Archives of Disease in Childhood. Mar, 2017 | Pubmed ID: 28213455 The 2.0 Å X-ray Structure for Yeast Acetohydroxyacid Synthase Provides New Insights into Its Cofactor and Quaternary Structure Requirements PloS One. 2017 | Pubmed ID: 28178302 Cytidine Deaminase Efficiency of the Lentiviral Viral Restriction Factor APOBEC3C Correlates with Dimerization Nucleic Acids Research. Feb, 2017 | Pubmed ID: 28158858 GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus Neoformans The Journal of Biological Chemistry. Feb, 2017 | Pubmed ID: 28062578 Conformational Variation of Proteins at Room Temperature is Not Dominated by Radiation Damage Journal of Synchrotron Radiation. Jan, 2017 | Pubmed ID: 28009548 Men with Duchenne Muscular Dystrophy and End of Life Planning Neuromuscular Disorders : NMD. Jan, 2017 | Pubmed ID: 27816330 Calculating the Cost and Risk of Comorbidities in Total Joint Arthroplasty in the United States The Journal of Arthroplasty. Feb, 2017 | Pubmed ID: 27623745 International Rates of Patellar Resurfacing in Primary Total Knee Arthroplasty, 2004-2014 The Journal of Arthroplasty. Jan, 2017 | Pubmed ID: 27421587 The Halo Effect: An Unintended Benefit of Care Pathways The Journal of Knee Surgery. Mar, 2017 | Pubmed ID: 27362923 Immunogenicity of a Peptide-based Anti-IgE Conjugate Vaccine in Non-human Primates Immunity, Inflammation and Disease. Jun, 2016 | Pubmed ID: 27957325 Cell-type-specific Expression of NFIX in the Developing and Adult Cerebellum Brain Structure & Function. Nov, 2016 | Pubmed ID: 27878595 Corrigendum: Determining Crystal Structures Through Crowdsourcing and Coursework Nature Communications. Oct, 2016 | Pubmed ID: 27779204 Disruption of De Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus Neoformans ACS Infectious Diseases. Sep, 2016 | Pubmed ID: 27759389 Targeted Genome Editing Via CRISPR in the Pathogen Cryptococcus Neoformans PloS One. 2016 | Pubmed ID: 27711143 Automated Structure Refinement of Macromolecular Assemblies from Cryo-EM Maps Using Rosetta ELife. Sep, 2016 | Pubmed ID: 27669148 Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus Neoformans PloS One. 2016 | Pubmed ID: 27643854 Determining Crystal Structures Through Crowdsourcing and Coursework Nature Communications. Sep, 2016 | Pubmed ID: 27633552 From Deep TLS Validation to Ensembles of Atomic Models Built from Elemental Motions. Addenda and Corrigendum Acta Crystallographica. Section D, Structural Biology. Sep, 2016 | Pubmed ID: 27599739 Patient Perception of Value in Bundled Payments for Total Joint Arthroplasty The Journal of Arthroplasty. Dec, 2016 | Pubmed ID: 27378636 SCIENTIFIC COMMUNITY. Preprints for the Life Sciences Science (New York, N.Y.). May, 2016 | Pubmed ID: 27199406 Benchmarking in Australia Using the International Foundations of Medicine Clinical Science Examination The Medical Journal of Australia. May, 2016 | Pubmed ID: 27169965 Determination of Ubiquitin Fitness Landscapes Under Different Chemical Stresses in a Classroom Setting ELife. Apr, 2016 | Pubmed ID: 27111525 Measuring and Modeling Diffuse Scattering in Protein X-ray Crystallography Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27035972 Metapopulation Viability of an Endangered Shorebird Depends on Dispersal and Human-created Habitats: Piping Plovers (Charadrius Melodus) and Prairie Rivers Movement Ecology. 2016 | Pubmed ID: 26981249 Data Publication with the Structural Biology Data Grid Supports Live Analysis Nature Communications. Mar, 2016 | Pubmed ID: 26947396 Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase Angewandte Chemie (International Ed. in English). Mar, 2016 | Pubmed ID: 26924714 High-density Grids for Efficient Data Collection from Multiple Crystals Acta Crystallographica. Section D, Structural Biology. Jan, 2016 | Pubmed ID: 26894529 Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of Commercial Wine Strains of Saccharomyces Cerevisiae G3 (Bethesda, Md.). Apr, 2016 | Pubmed ID: 26869621 CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites Journal of Molecular Biology. Feb, 2016 | Pubmed ID: 26854760 Antibacterial and Antifungal Screening of Natural Products Sourced from Australian Fungi and Characterisation of Pestalactams D-F Phytochemistry. Apr, 2016 | Pubmed ID: 26743853 Automated 3D Bone Ablation with 1,070 nm Ytterbium-doped Fiber Laser Enabled by Inline Coherent Imaging Lasers in Surgery and Medicine. Mar, 2016 | Pubmed ID: 26718116 Impact of Neuraminidase Inhibitors on Influenza A(H1N1)pdm09-related Pneumonia: an Individual Participant Data Meta-analysis Influenza and Other Respiratory Viruses. May, 2016 | Pubmed ID: 26602067 The Morbidity and Mortality Meeting: Time for a Different Approach? Archives of Disease in Childhood. Jan, 2016 | Pubmed ID: 26566689 The RyR2-P2328S Mutation Downregulates Nav1.5 Producing Arrhythmic Substrate in Murine Ventricles Pflugers Archiv : European Journal of Physiology. Apr, 2016 | Pubmed ID: 26545784 Hierarchical Folding and Reorganization of Chromosomes Are Linked to Transcriptional Changes in Cellular Differentiation Molecular Systems Biology. Dec, 2015 | Pubmed ID: 26700852 High-resolution Structures of the M2 Channel from Influenza A Virus Reveal Dynamic Pathways for Proton Stabilization and Transduction Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26578770 Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using QFit PLoS Computational Biology. Oct, 2015 | Pubmed ID: 26506617 Polyploid Titan Cells Produce Haploid and Aneuploid Progeny to Promote Stress Adaptation MBio. Oct, 2015 | Pubmed ID: 26463162 Mapping the Conformational Landscape of a Dynamic Enzyme by Multitemperature and XFEL Crystallography ELife. Sep, 2015 | Pubmed ID: 26422513 Comparative Genomics of Non-pseudomonal Bacterial Species Colonising Paediatric Cystic Fibrosis Patients PeerJ. 2015 | Pubmed ID: 26401445 Whole-genome Sequencing Identifies EN1 As a Determinant of Bone Density and Fracture Nature. Oct, 2015 | Pubmed ID: 26367794 Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium Congestum Journal of Natural Products. Aug, 2015 | Pubmed ID: 26284978 EMRinger: Side Chain-directed Model and Map Validation for 3D Cryo-electron Microscopy Nature Methods. Oct, 2015 | Pubmed ID: 26280328 From Deep TLS Validation to Ensembles of Atomic Models Built from Elemental Motions Acta Crystallographica. Section D, Biological Crystallography. Aug, 2015 | Pubmed ID: 26249348 Predicting X-ray Diffuse Scattering from Translation-libration-screw Structural Ensembles Acta Crystallographica. Section D, Biological Crystallography. Aug, 2015 | Pubmed ID: 26249347 An Overview of Genome Organization and How We Got There: from FISH to Hi-C Microbiology and Molecular Biology Reviews : MMBR. Sep, 2015 | Pubmed ID: 26223848 Complete Genome Sequence of Sporisorium Scitamineum and Biotrophic Interaction Transcriptome with Sugarcane PloS One. 2015 | Pubmed ID: 26065709 One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites Chembiochem : a European Journal of Chemical Biology. Jul, 2015 | Pubmed ID: 26032594 Negative Epistasis and Evolvability in TEM-1 β-Lactamase--The Thin Line Between an Enzyme's Conformational Freedom and Disorder Journal of Molecular Biology. Jul, 2015 | Pubmed ID: 26004540 Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity Cell Reports. May, 2015 | Pubmed ID: 25981045 A Genomic Safe Haven for Mutant Complementation in Cryptococcus Neoformans PloS One. 2015 | Pubmed ID: 25856300 Integrative, Dynamic Structural Biology at Atomic Resolution--it's About Time Nature Methods. Apr, 2015 | Pubmed ID: 25825836 Differential Regenerative Capacity of Neonatal Mouse Hearts After Cryoinjury Developmental Biology. Mar, 2015 | Pubmed ID: 25555840 Keep on Moving: Discovering and Perturbing the Conformational Dynamics of Enzymes Accounts of Chemical Research. Feb, 2015 | Pubmed ID: 25539415 Wear and Loosening in Total Knee Arthroplasty: a Quick Review The Journal of Knee Surgery. Apr, 2015 | Pubmed ID: 25539400 The Gown-glove Interface Is a Source of Contamination: A Comparative Study Clinical Orthopaedics and Related Research. Jul, 2015 | Pubmed ID: 25488405 Conformational Dynamics of a Crystalline Protein from Microsecond-scale Molecular Dynamics Simulations and Diffuse X-ray Scattering Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453071 The Determinants of Transverse Tubular Volume in Resting Skeletal Muscle The Journal of Physiology. Dec, 2014 | Pubmed ID: 25384782 Discovery and Characterization of Gut Microbiota Decarboxylases That Can Produce the Neurotransmitter Tryptamine Cell Host & Microbe. Oct, 2014 | Pubmed ID: 25263219 Understanding Why Children Die in High-income Countries Lancet (London, England). Sep, 2014 | Pubmed ID: 25209491 Patterns of Child Death in England and Wales Lancet (London, England). Sep, 2014 | Pubmed ID: 25209490 Learning from Child Death Review in the USA, England, Australia, and New Zealand Lancet (London, England). Sep, 2014 | Pubmed ID: 25209489 Child Death in High-income Countries Lancet (London, England). Sep, 2014 | Pubmed ID: 25209471 Increased Transfusion-free Survival Following Auxiliary Pig Liver Xenotransplantation Xenotransplantation. Sep-Oct, 2014 | Pubmed ID: 25130043 E Pluribus Unum, No More: from One Crystal, Many Conformations Current Opinion in Structural Biology. Oct, 2014 | Pubmed ID: 25113271 Cryptococcus Neoformans and Cryptococcus Gattii, the Etiologic Agents of Cryptococcosis Cold Spring Harbor Perspectives in Medicine. Jul, 2014 | Pubmed ID: 24985132 Incorporation of Protein Flexibility and Conformational Energy Penalties in Docking Screens to Improve Ligand Discovery Nature Chemistry. Jul, 2014 | Pubmed ID: 24950326 Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR Structure (London, England : 1993). Jun, 2014 | Pubmed ID: 24882744 Analysis of the Genome and Transcriptome of Cryptococcus Neoformans Var. Grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation PLoS Genetics. Apr, 2014 | Pubmed ID: 24743168 Mkk4 is a Negative Regulator of the Transforming Growth Factor Beta 1 Signaling Associated with Atrial Remodeling and Arrhythmogenesis with Age Journal of the American Heart Association. Apr, 2014 | Pubmed ID: 24721794 Measurement and Interpretation of Electrocardiographic QT Intervals in Murine Hearts American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2014 | Pubmed ID: 24705556 Teaching and Physics Education Research: Bridging the Gap Reports on Progress in Physics. Physical Society (Great Britain). Mar, 2014 | Pubmed ID: 24595011 Multiple Nuclear Localization Signals Mediate Nuclear Localization of the GATA Transcription Factor AreA Eukaryotic Cell. Apr, 2014 | Pubmed ID: 24562911 A Conceptual Model of the Role of Complexity in the Care of Patients with Multiple Chronic Conditions Medical Care. Mar, 2014 | Pubmed ID: 24561762 Antimicrobial Distribution from Local Delivery Depends on Dose : a Pilot Study with MRI Clinical Orthopaedics and Related Research. Nov, 2014 | Pubmed ID: 24510357 Diffuse X-ray Scattering to Model Protein Motions Structure (London, England : 1993). Feb, 2014 | Pubmed ID: 24507780 Functional Consequences of NKCC2 Splice Isoforms: Insights from a Xenopus Oocyte Model American Journal of Physiology. Renal Physiology. Apr, 2014 | Pubmed ID: 24477685 Integrated Description of Protein Dynamics from Room-temperature X-ray Crystallography and NMR Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24474795 Protein Structural Ensembles Are Revealed by Redefining X-ray Electron Density Noise Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24363322 Improving the Practice of Child Death Overview Panels: a Paediatric Perspective Archives of Disease in Childhood. Mar, 2014 | Pubmed ID: 24255566 The SCN5A Mutation A1180V is Associated with Electrocardiographic Features of LQT3 Pediatric Cardiology. Feb, 2014 | Pubmed ID: 23963187 Balancing Stability and Flexibility Within the Genome of the Pathogen Cryptococcus Neoformans PLoS Pathogens. 2013 | Pubmed ID: 24348244 Repurposing CRISPR/Cas9 for in Situ Functional Assays Genes & Development. Dec, 2013 | Pubmed ID: 24298059 Purification, Crystallization and Preliminary X-ray Analysis of Adenylosuccinate Synthetase from the Fungal Pathogen Cryptococcus Neoformans Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2013 | Pubmed ID: 23989157 From Structure to Systems: High-resolution, Quantitative Genetic Analysis of RNA Polymerase II Cell. Aug, 2013 | Pubmed ID: 23932120 Automated Identification of Functional Dynamic Contact Networks from X-ray Crystallography Nature Methods. Sep, 2013 | Pubmed ID: 23913260 Secondary Metabolites of the Sponge-derived Fungus Acremonium Persicinum Journal of Natural Products. Aug, 2013 | Pubmed ID: 23883432 Determinants of Myocardial Conduction Velocity: Implications for Arrhythmogenesis Frontiers in Physiology. 2013 | Pubmed ID: 23825462 A Polymer Model Explains the Complexity of Large-scale Chromatin Folding Nucleus (Austin, Tex.). Jul-Aug, 2013 | Pubmed ID: 23823730 Is the Nickel-dependent Urease Complex of Cryptococcus the Pathogen's Achilles' Heel? MBio. Jun, 2013 | Pubmed ID: 23800398 Phase I Dose Escalation Study of Bortezomib in Combination with Lenalidomide in Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Leukemia Research. Sep, 2013 | Pubmed ID: 23773898 "It's Common Sense That It's Wrong": Young People's Perceptions and Experiences of Cyberbullying Cyberpsychology, Behavior and Social Networking. Nov, 2013 | Pubmed ID: 23745618 Loss of Nav1.5 Expression and Function in Murine Atria Containing the RyR2-P2328S Gain-of-function Mutation Cardiovascular Research. Sep, 2013 | Pubmed ID: 23723061 Deep Nonlinear Ablation of Silicon with a Quasi-continuous Wave Fiber Laser at 1070 Nm Optics Letters. Jun, 2013 | Pubmed ID: 23722748 Nitrogen Regulation of Virulence in Clinically Prevalent Fungal Pathogens FEMS Microbiology Letters. Aug, 2013 | Pubmed ID: 23701678 Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus Neoformans PloS One. 2013 | Pubmed ID: 23667704 Extracellular Magnesium and Calcium Reduce Myotonia in ClC-1 Inhibited Rat Muscle Neuromuscular Disorders : NMD. Jun, 2013 | Pubmed ID: 23623567 Reactive Oxygen Species Homeostasis and Virulence of the Fungal Pathogen Cryptococcus Neoformans Requires an Intact Proline Catabolism Pathway Genetics. Jun, 2013 | Pubmed ID: 23564202 Comparative Genomics of Serial Isolates of Cryptococcus Neoformans Reveals Gene Associated With Carbon Utilization and Virulence G3 (Bethesda, Md.). Apr, 2013 | Pubmed ID: 23550133 Appropriateness of Imaging in Canada Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes. May, 2013 | Pubmed ID: 23528386 A Model of the Large-scale Organization of Chromatin Biochemical Society Transactions. Apr, 2013 | Pubmed ID: 23514144 Flexible Backbone Sampling Methods to Model and Design Protein Alternative Conformations Methods in Enzymology. 2013 | Pubmed ID: 23422426 Ploidy Variation As an Adaptive Mechanism in Human Pathogenic Fungi Seminars in Cell & Developmental Biology. Apr, 2013 | Pubmed ID: 23380396 From Systems to Structure: Bridging Networks and Mechanism Molecular Cell. Jan, 2013 | Pubmed ID: 23352243 Sulfonylureas Have Antifungal Activity and Are Potent Inhibitors of Candida Albicans Acetohydroxyacid Synthase Journal of Medicinal Chemistry. Jan, 2013 | Pubmed ID: 23237384 Conduction Slowing Contributes to Spontaneous Ventricular Arrhythmias in Intrinsically Active Murine RyR2-P2328S Hearts Journal of Cardiovascular Electrophysiology. Feb, 2013 | Pubmed ID: 23131176 De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans PLoS Pathogens. 2012 | Pubmed ID: 23071437 Complexity of Chromatin Folding is Captured by the Strings and Binders Switch Model Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 22988072 In Support of the BMRB Nature Structural & Molecular Biology. Sep, 2012 | Pubmed ID: 22955930 Convergent Adaptations: Bitter Manioc Cultivation Systems in Fertile Anthropogenic Dark Earths and Floodplain Soils in Central Amazonia PloS One. 2012 | Pubmed ID: 22952727 CheShift-2 Resolves a Local Inconsistency Between Two X-ray Crystal Structures Journal of Biomolecular NMR. Oct, 2012 | Pubmed ID: 22945426 A Torrent of Data: Mapping Chromatin Organization Using 5C and High-throughput Sequencing Methods in Enzymology. 2012 | Pubmed ID: 22929767 Systematic Functional Prioritization of Protein Posttranslational Modifications Cell. Jul, 2012 | Pubmed ID: 22817900 Anti-interleukin-10R1 Monoclonal Antibody Enhances Bacillus Calmette-Guérin Induced T-helper Type 1 Immune Responses and Antitumor Immunity in a Mouse Orthotopic Model of Bladder Cancer The Journal of Urology. Jun, 2012 | Pubmed ID: 22503050 Characterization of an Nmr Homolog That Modulates GATA Factor-mediated Nitrogen Metabolite Repression in Cryptococcus Neoformans PloS One. 2012 | Pubmed ID: 22470421 Control of Protein Signaling Using a Computationally Designed GTPase/GEF Orthogonal Pair Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22403064 A Unique Chromosomal Rearrangement in the Cryptococcus Neoformans Var. Grubii Type Strain Enhances Key Phenotypes Associated with Virulence MBio. 2012 | Pubmed ID: 22375073 Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus Amylolentus and the Evolution of MAT in the Cryptococcus Species Complex PLoS Genetics. 2012 | Pubmed ID: 22359516 Quantifying and Comparing Torsional Strains After Olecranon Plating Injury. Jun, 2012 | Pubmed ID: 22348953 Microevolution of Cryptococcus Neoformans Driven by Massive Tandem Gene Amplification Molecular Biology and Evolution. Aug, 2012 | Pubmed ID: 22334577 Altered Sinoatrial Node Function and Intra-atrial Conduction in Murine Gain-of-function Scn5a+/ΔKPQ Hearts Suggest an Overlap Syndrome American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2012 | Pubmed ID: 22287583 Real-time Guidance of Thermal and Ultrashort Pulsed Laser Ablation in Hard Tissue Using Inline Coherent Imaging Lasers in Surgery and Medicine. Mar, 2012 | Pubmed ID: 22241665 Dimethyl Sulphoxide Addition or Withdrawal Causes Biphasic Volume Changes and Its Withdrawal Causes T-system Vacuolation in Skeletal Muscle The Journal of Physiology. Nov, 2011 | Pubmed ID: 22086252 Three-dimensional Modeling of Chromatin Structure from Interaction Frequency Data Using Markov Chain Monte Carlo Sampling BMC Bioinformatics. Oct, 2011 | Pubmed ID: 22026390 Reciprocal Dihydropyridine and Ryanodine Receptor Interactions in Skeletal Muscle Activation Journal of Muscle Research and Cell Motility. Nov, 2011 | Pubmed ID: 21993921 Accessing Protein Conformational Ensembles Using Room-temperature X-ray Crystallography Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21918110 A Diverse Population of Cryptococcus Gattii Molecular Type VGIII in Southern Californian HIV/AIDS Patients PLoS Pathogens. Sep, 2011 | Pubmed ID: 21909264 An Analysis of the Relationships Between Subthreshold Electrical Properties and Excitability in Skeletal Muscle The Journal of General Physiology. Jul, 2011 | Pubmed ID: 21670208 Relationships Between Resting Conductances, Excitability, and T-system Ionic Homeostasis in Skeletal Muscle The Journal of General Physiology. Jul, 2011 | Pubmed ID: 21670205 Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus Neoformans Genetics. Jun, 2011 | Pubmed ID: 21441208 Increasing Prevalence of Domiciliary Ventilation: Changes in Service Demand and Provision in the South West of the UK European Journal of Pediatrics. Sep, 2011 | Pubmed ID: 21360027 Repetitive Flood Victims and Acceptance of FEMA Mitigation Offers: an Analysis with Community-system Policy Implications Disasters. Jul, 2011 | Pubmed ID: 21272056 The Underwater Photic Environment of Cape Maclear, Lake Malawi: Comparison Between Rock- and Sand-bottom Habitats and Implications for Cichlid Fish Vision The Journal of Experimental Biology. Feb, 2011 | Pubmed ID: 21228208 Mining Electron Density for Functionally Relevant Protein Polysterism in Crystal Structures Cellular and Molecular Life Sciences : CMLS. Jun, 2011 | Pubmed ID: 21190057 Acute Atrial Arrhythmogenicity and Altered Ca(2+) Homeostasis in Murine RyR2-P2328S Hearts Cardiovascular Research. Mar, 2011 | Pubmed ID: 20621925 The Tumor-associated EpCAM Regulates Morphogenetic Movements Through Intracellular Signaling The Journal of Cell Biology. Nov, 2010 | Pubmed ID: 20974811 Computing Chromosome Conformation Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20827597 Crystallization and Preliminary X-ray Analysis of Mycophenolic Acid-resistant and Mycophenolic Acid-sensitive Forms of IMP Dehydrogenase from the Human Fungal Pathogen Cryptococcus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2010 | Pubmed ID: 20823538 Automated Electron-density Sampling Reveals Widespread Conformational Polymorphism in Proteins Protein Science : a Publication of the Protein Society. Jul, 2010 | Pubmed ID: 20499387 America's Fertile Frontier: How America Surpassed Britain in the Development and Growth of Plastic Surgery During the Interwar Years of 1920-1940 Annals of Plastic Surgery. May, 2010 | Pubmed ID: 20395812 Comprehensive Management of Hot-press Hand Injuries: Long-term Outcomes Following Reconstruction and Rehabilitation Annals of Plastic Surgery. May, 2010 | Pubmed ID: 20395811 Saturation of the Photoluminescence at Few-exciton Levels in a Single-walled Carbon Nanotube Under Ultrafast Excitation Physical Review Letters. Jan, 2010 | Pubmed ID: 20366391 In Situ 24 KHz Coherent Imaging of Morphology Change in Laser Percussion Drilling Optics Letters. Mar, 2010 | Pubmed ID: 20195306 Accidental Ingestion of Dosulepin Presenting As Atrial Flutter in a Child European Journal of Pediatrics. Jan, 2010 | Pubmed ID: 19347362 Hidden Alternative Structures of Proline Isomerase Essential for Catalysis Nature. Dec, 2009 | Pubmed ID: 19956261 Prevalence of Antibodies to West Nile Virus and Other Arboviruses Among Crested Caracaras (Caracara Cheriway) in Florida Journal of Wildlife Diseases. Jul, 2009 | Pubmed ID: 19617494 Chromatin Conformation Signatures of Cellular Differentiation Genome Biology. 2009 | Pubmed ID: 19374771 Contrast Improvement in Fourier-domain Optical Coherence Tomography Through Time Gating Journal of the Optical Society of America. A, Optics, Image Science, and Vision. Apr, 2009 | Pubmed ID: 19340272 Sexual Reproduction and Dimorphism in the Pathogenic Basidiomycetes FEMS Yeast Research. Mar, 2009 | Pubmed ID: 19220864 Control of Cell Volume in Skeletal Muscle Biological Reviews of the Cambridge Philosophical Society. Feb, 2009 | Pubmed ID: 19133959 Pharmacological Characterization of a Small Molecule Inhibitor of C-Jun Kinase American Journal of Physiology. Endocrinology and Metabolism. Nov, 2008 | Pubmed ID: 18728225 Transitions in Sexuality: Recapitulation of an Ancestral Tri- and Tetrapolar Mating System in Cryptococcus Neoformans Eukaryotic Cell. Oct, 2008 | Pubmed ID: 18723606 Translational Imaging Studies of Cortical Spreading Depression in Experimental Models for Migraine Aura Expert Review of Neurotherapeutics. May, 2008 | Pubmed ID: 18457533 Extracellular Charge Adsorption Influences Intracellular Electrochemical Homeostasis in Amphibian Skeletal Muscle Biophysical Journal. Jun, 2008 | Pubmed ID: 18310253 High Speed in Situ Depth Profiling of Ultrafast Micromachining Optics Express. Nov, 2007 | Pubmed ID: 19550777 Similarities and Contrasts in Ryanodine Receptor Localization and Function in Osteoclasts and Striated Muscle Cells Annals of the New York Academy of Sciences. Nov, 2007 | Pubmed ID: 18083933 Time-gated Fourier-domain Optical Coherence Tomography Optics Letters. Nov, 2007 | Pubmed ID: 18026299 Birnbaum LM, Filion KB, Joyal D, Eisenberg MJ. Second Reading of Coronary Angiograms by Radiologists. Can J Cardiol 2006;22(14):1217-1221 The Canadian Journal of Cardiology. Sep, 2007 | Pubmed ID: 17907348 Immunoglobulin-like Domains on Bacteriophage: Weapons of Modest Damage? Current Opinion in Microbiology. Aug, 2007 | Pubmed ID: 17765600 First Contemporary Case of Human Infection with Cryptococcus Gattii in Puget Sound: Evidence for Spread of the Vancouver Island Outbreak Journal of Clinical Microbiology. Sep, 2007 | Pubmed ID: 17596366 An Atypical Receiver Domain Controls the Dynamic Polar Localization of the Myxococcus Xanthus Social Motility Protein FrzS Molecular Microbiology. Jul, 2007 | Pubmed ID: 17573816 Distribution Patterns of Estrogen Receptor Alpha and Beta in the Human Cortex and Hippocampus During Development and Adulthood The Journal of Comparative Neurology. Aug, 2007 | Pubmed ID: 17570500 A Quantitative Analysis of the Effect of Cycle Length on Arrhythmogenicity in Hypokalaemic Langendorff-perfused Murine Hearts Pflugers Archiv : European Journal of Physiology. Sep, 2007 | Pubmed ID: 17437126 Evolution of the Mating Type Locus: Insights Gained from the Dimorphic Primary Fungal Pathogens Histoplasma Capsulatum, Coccidioides Immitis, and Coccidioides Posadasii Eukaryotic Cell. Apr, 2007 | Pubmed ID: 17337636 Alterations in Triad Ultrastructure Following Repetitive Stimulation and Intracellular Changes Associated with Exercise in Amphibian Skeletal Muscle Journal of Muscle Research and Cell Motility. 2007 | Pubmed ID: 17333488 The Contribution of Refractoriness to Arrhythmic Substrate in Hypokalemic Langendorff-perfused Murine Hearts Pflugers Archiv : European Journal of Physiology. May, 2007 | Pubmed ID: 17295037 Heat-induced Dimerization of BCL-xL Through Alpha-helix Swapping Biochemistry. Jan, 2007 | Pubmed ID: 17223694 Quantitative Techniques for Steady-state Calculation and Dynamic Integrated Modelling of Membrane Potential and Intracellular Ion Concentrations Progress in Biophysics and Molecular Biology. Jul, 2007 | Pubmed ID: 17129600 Biochemical Signal Detection in Miniaturized Fluidic Systems by Integrated Microresonator Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2006 | Pubmed ID: 17946809 Membrane Potentials in Rana Temporaria Muscle Fibres in Strongly Hypertonic Solutions Journal of Muscle Research and Cell Motility. 2006 | Pubmed ID: 17051346 Characterization of Estrogen Receptors Alpha and Beta in Uterine Leiomyoma Cells Fertility and Sterility. Dec, 2006 | Pubmed ID: 17011556 Pyridine-2-propanoic Acids: Discovery of Dual PPARalpha/gamma Agonists As Antidiabetic Agents Bioorganic & Medicinal Chemistry Letters. Dec, 2006 | Pubmed ID: 16979341 Pyridine-3-propanoic Acids: Discovery of Dual PPARalpha/gamma Agonists As Antidiabetic Agents Bioorganic & Medicinal Chemistry Letters. Dec, 2006 | Pubmed ID: 16973358 Alterations in Calcium Homeostasis Reduce Membrane Excitability in Amphibian Skeletal Muscle Pflugers Archiv : European Journal of Physiology. Nov, 2006 | Pubmed ID: 16955310 Recent Evolution of the Human Pathogen Cryptococcus Neoformans by Intervarietal Transfer of a 14-gene Fragment Molecular Biology and Evolution. Oct, 2006 | Pubmed ID: 16870684 Parametric Cascade Downconverter for Intense Ultrafast Mid-infrared Generation Beyond the Manley-Rowe Limit Applied Optics. Jun, 2006 | Pubmed ID: 16761052 Yeast Diversity Sampling on the San Juan Islands Reveals No Evidence for the Spread of the Vancouver Island Cryptococcus Gattii Outbreak to This Locale FEMS Yeast Research. Jun, 2006 | Pubmed ID: 16696658 Ig-like Domains on Bacteriophages: a Tale of Promiscuity and Deceit Journal of Molecular Biology. Jun, 2006 | Pubmed ID: 16631788 The Influence of Intracellular Lactate and H+ on Cell Volume in Amphibian Skeletal Muscle The Journal of Physiology. Jun, 2006 | Pubmed ID: 16613877 Effect of Repetitive Stimulation on Cell Volume and Its Relationship to Membrane Potential in Amphibian Skeletal Muscle Pflugers Archiv : European Journal of Physiology. May, 2006 | Pubmed ID: 16404610 Same-sex Mating and the Origin of the Vancouver Island Cryptococcus Gattii Outbreak Nature. Oct, 2005 | Pubmed ID: 16222245 Nuclear Accumulation of the GATA Factor AreA in Response to Complete Nitrogen Starvation by Regulation of Nuclear Export Eukaryotic Cell. Oct, 2005 | Pubmed ID: 16215172 Chromosomal Sex-determining Regions in Animals, Plants and Fungi Current Opinion in Genetics & Development. Dec, 2005 | Pubmed ID: 16182521 Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans Nature Reviews. Microbiology. Oct, 2005 | Pubmed ID: 16132036 Clinical and Environmental Isolates of Cryptococcus Gattii from Australia That Retain Sexual Fecundity Eukaryotic Cell. Aug, 2005 | Pubmed ID: 16087746 Chromosomal Translocation and Segmental Duplication in Cryptococcus Neoformans Eukaryotic Cell. Feb, 2005 | Pubmed ID: 15701802 The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus Neoformans Science (New York, N.Y.). Feb, 2005 | Pubmed ID: 15653466 Slow Volume Transients in Amphibian Skeletal Muscle Fibres Studied in Hypotonic Solutions The Journal of Physiology. Apr, 2005 | Pubmed ID: 15649980 The Effect of Intracellular Acidification on the Relationship Between Cell Volume and Membrane Potential in Amphibian Skeletal Muscle The Journal of Physiology. Mar, 2005 | Pubmed ID: 15618273 2-Alkoxydihydrocinnamates As PPAR Agonists. Activity Modulation by the Incorporation of Phenoxy Substituents Bioorganic & Medicinal Chemistry Letters. Jan, 2005 | Pubmed ID: 15582409 Detubulation Experiments Localise Delayed Rectifier Currents to the Surface Membrane of Amphibian Skeletal Muscle Fibres Journal of Muscle Research and Cell Motility. 2004 | Pubmed ID: 15548868 Detubulation Abolishes Membrane Potential Stabilization in Amphibian Skeletal Muscle Journal of Muscle Research and Cell Motility. 2004 | Pubmed ID: 15548867 Convergent Evolution of Chromosomal Sex-determining Regions in the Animal and Fungal Kingdoms PLoS Biology. Dec, 2004 | Pubmed ID: 15538538 Improving Treatment Services for Substance Abusers with Comorbid Depression The American Journal on Addictions. May-Jun, 2004 | Pubmed ID: 15370949 Coherent Vibrational Climbing in Carboxyhemoglobin Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15319472 PAK Kinases Ste20 and Pak1 Govern Cell Polarity at Different Stages of Mating in Cryptococcus Neoformans Molecular Biology of the Cell. Oct, 2004 | Pubmed ID: 15282344 A Quantitative Analysis of Cell Volume and Resting Potential Determination and Regulation in Excitable Cells The Journal of Physiology. Sep, 2004 | Pubmed ID: 15243134 Venous Protocols, Techniques, and Interpretations of the Upper and Lower Extremities Radiologic Clinics of North America. Mar, 2004 | Pubmed ID: 15136017 Isolatie, karakterisering en zuivering van macrofagen uit weefsels beïnvloed door zwaarlijvigheidbetrekking hebbende ontsteking Joselyn N. Allen1, Adwitia Dey1, Ruth Nissly2, James Fraser1, Shan Yu1, Gayathri Balandaram1, Jeffrey M. Peters1, Pamela A. Hankey-Giblin1 1Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 2Microscopy and Cytometry Facility, The Huck Institutes of Life Sciences, Pennsylvania State University JoVE 55445 Immunology and Infection
Isolatie, karakterisering en zuivering van macrofagen uit weefsels beïnvloed door zwaarlijvigheidbetrekking hebbende ontsteking Joselyn N. Allen1, Adwitia Dey1, Ruth Nissly2, James Fraser1, Shan Yu1, Gayathri Balandaram1, Jeffrey M. Peters1, Pamela A. Hankey-Giblin1 1Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 2Microscopy and Cytometry Facility, The Huck Institutes of Life Sciences, Pennsylvania State University JoVE 55445 Immunology and Infection