Jean Gruenberg

Publications

• LLOMe Does Not Release Cysteine Cathepsins to the Cytosol but Inactivates Them in Transiently Permeabilized Lysosomes
  Journal of Cell Science. Jul, 2017  |   Pubmed ID: 28754686
• Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs
  Chimia. Dec, 2016  |   Pubmed ID: 28661361
• Moesin and Cortactin Control Actin-dependent Multivesicular Endosome Biogenesis
  Molecular Biology of the Cell. Nov, 2016  |   Pubmed ID: 27605702
• Selective Imaging of Late Endosomes with a PH-Sensitive Diazaoxatriangulene Fluorescent Probe
  Journal of the American Chemical Society. Feb, 2016  |   Pubmed ID: 26799309
• Secondary Structure and (1)H, (13)C, (15)N Resonance Assignments of the Endosomal Sorting Protein Sorting Nexin 3
  Biomolecular NMR Assignments. Oct, 2015  |   Pubmed ID: 25893673
• Wnt Directs the Endosomal Flux of LDL-derived Cholesterol and Lipid Droplet Homeostasis
  EMBO Reports. Jun, 2015  |   Pubmed ID: 25851648
• Close Encounter of the Third Kind: the ER Meets Endosomes at Fission Sites
  Developmental Cell. Dec, 2014  |   Pubmed ID: 25535914
• Discovery of Novel Membrane Binding Structures and Functions
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Dec, 2014  |   Pubmed ID: 25394204
• Endosome Maturation, Transport and Functions
  Seminars in Cell & Developmental Biology. Jul, 2014  |   Pubmed ID: 24709024
• ALIX and the Multivesicular Endosome: ALIX in Wonderland
  Trends in Cell Biology. Jan, 2014  |   Pubmed ID: 24287454
• Lipid Sorting and Multivesicular Endosome Biogenesis
  Cold Spring Harbor Perspectives in Biology. Oct, 2013  |   Pubmed ID: 24086044
• Viral Infection Controlled by a Calcium-dependent Lipid-binding Module in ALIX
  Developmental Cell. May, 2013  |   Pubmed ID: 23664863
• PNPLA3/adiponutrin Functions in Lipid Droplet Formation
  Biology of the Cell. May, 2013  |   Pubmed ID: 23398201
• An MBoC Favorite: Functional Interactions Between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology
  Molecular Biology of the Cell. Jul, 2012  |   Pubmed ID: 22745339
• SNX12 Role in Endosome Membrane Transport
  PloS One. 2012  |   Pubmed ID: 22719997
• Single-cell Analysis of Population Context Advances RNAi Screening at Multiple Levels
  Molecular Systems Biology. Apr, 2012  |   Pubmed ID: 22531119
• Regulation of the EGF Transcriptional Response by Endocytic Sorting
  Science Signaling. Mar, 2012  |   Pubmed ID: 22416276
• Studying Lipids Involved in the Endosomal Pathway
  Methods in Cell Biology. 2012  |   Pubmed ID: 22325596
• Regulation of the MVB Pathway by SCAMP3
  Traffic (Copenhagen, Denmark). Jan, 2012  |   Pubmed ID: 21951651
• A Novel Strategy to Identify Drugs That Interfere with Endosomal Lipids
  Chimia. 2011  |   Pubmed ID: 22289369
• Duelling Functions of the V-ATPase
  The EMBO Journal. Oct, 2011  |   Pubmed ID: 22009224
• Role of SNX16 in the Dynamics of Tubulo-cisternal Membrane Domains of Late Endosomes
  PloS One. 2011  |   Pubmed ID: 21754999
• Role of AP1 and Gadkin in the Traffic of Secretory Endo-lysosomes
  Molecular Biology of the Cell. Jun, 2011  |   Pubmed ID: 21525240
• Ion Flux and the Function of Endosomes and Lysosomes: PH is Just the Start: the Flux of Ions Across Endosomal Membranes Influences Endosome Function Not Only Through Regulation of the Luminal PH
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2011  |   Pubmed ID: 21140470
• The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization
  Chimia. Dec, 2009  |   Pubmed ID: 28372605
• Viruses and Endosome Membrane Dynamics
  Current Opinion in Cell Biology. Aug, 2009  |   Pubmed ID: 19443190
• Annexin A2-dependent Polymerization of Actin Mediates Endosome Biogenesis
  Developmental Cell. Mar, 2009  |   Pubmed ID: 19289089
• Molecular Assemblies and Membrane Domains in Multivesicular Endosome Dynamics
  Experimental Cell Research. May, 2009  |   Pubmed ID: 19133258
• Annexin A2 Binding to Endosomes and Functions in Endosomal Transport Are Regulated by Tyrosine 23 Phosphorylation
  The Journal of Biological Chemistry. Jan, 2009  |   Pubmed ID: 18990701
• The ESCRT-I Subunit TSG101 Controls Endosome-to-cytosol Release of Viral RNA
  Traffic (Copenhagen, Denmark). Dec, 2008  |   Pubmed ID: 18817529
• In Vitro Budding of Intralumenal Vesicles into Late Endosomes is Regulated by Alix and Tsg101
  Molecular Biology of the Cell. Nov, 2008  |   Pubmed ID: 18768755
• Hrs and SNX3 Functions in Sorting and Membrane Invagination Within Multivesicular Bodies
  PLoS Biology. Sep, 2008  |   Pubmed ID: 18767904
• Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels
  The Journal of Biological Chemistry. Oct, 2008  |   Pubmed ID: 18644787
• Down Syndrome Fibroblast Model of Alzheimer-related Endosome Pathology: Accelerated Endocytosis Promotes Late Endocytic Defects
  The American Journal of Pathology. Aug, 2008  |   Pubmed ID: 18535180
• The Cargo Receptors Surf4, Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)-53, and P25 Are Required to Maintain the Architecture of ERGIC and Golgi
  Molecular Biology of the Cell. May, 2008  |   Pubmed ID: 18287528
• The Redox Sensor TXNL1 Plays a Regulatory Role in Fluid Phase Endocytosis
  PloS One. Nov, 2007  |   Pubmed ID: 17987124
• The P11/S100A10 Light Chain of Annexin A2 is Dispensable for Annexin A2 Association to Endosomes and Functions in Endosomal Transport
  PloS One. Oct, 2007  |   Pubmed ID: 17971878
• Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-endosomal Trafficking
  PloS One. Sep, 2007  |   Pubmed ID: 17786222
• Core Protein Machinery for Mammalian Phosphatidylinositol 3,5-bisphosphate Synthesis and Turnover That Regulates the Progression of Endosomal Transport. Novel Sac Phosphatase Joins the ArPIKfyve-PIKfyve Complex
  The Journal of Biological Chemistry. Aug, 2007  |   Pubmed ID: 17556371
• Diversity of Raft-like Domains in Late Endosomes
  PloS One. Apr, 2007  |   Pubmed ID: 17460758
• Intracellular Trafficking of Interleukin-1 Receptor I Requires Tollip
  Current Biology : CB. Nov, 2006  |   Pubmed ID: 17113392
• Intra-endosomal Membrane Traffic
  Trends in Cell Biology. Oct, 2006  |   Pubmed ID: 16949287
• Mechanisms of Pathogen Entry Through the Endosomal Compartments
  Nature Reviews. Molecular Cell Biology. Jul, 2006  |   Pubmed ID: 16773132
• Toxoplasma: Guess Who's Coming to Dinner
  Cell. Apr, 2006  |   Pubmed ID: 16630810
• Capture of the Small GTPase Rab5 by GDI: Regulation by P38 MAP Kinase
  Methods in Enzymology. 2005  |   Pubmed ID: 16473603
• [Endocytosis: the Trojan Horse of Viral Infection]
  Medecine Sciences : M/S. Nov, 2005  |   Pubmed ID: 16274637
• Concise Synthesis of Ether Analogues of Lysobisphosphatidic Acid
  Organic Letters. Sep, 2005  |   Pubmed ID: 16119911
• The Secreted Form of Dengue Virus Nonstructural Protein NS1 is Endocytosed by Hepatocytes and Accumulates in Late Endosomes: Implications for Viral Infectivity
  Journal of Virology. Sep, 2005  |   Pubmed ID: 16103191
• Subcellular Fractionation of Tissue Culture Cells
  Current Protocols in Protein Science. Aug, 2004  |   Pubmed ID: 18429269
• ARF1 Regulates Nef-induced CD4 Degradation
  Current Biology : CB. Jun, 2004  |   Pubmed ID: 15202998
• Acquisition of Hrs, an Essential Component of Phagosomal Maturation, is Impaired by Mycobacteria
  Molecular and Cellular Biology. May, 2004  |   Pubmed ID: 15121875
• The Biogenesis of Multivesicular Endosomes
  Nature Reviews. Molecular Cell Biology. Apr, 2004  |   Pubmed ID: 15071556
• Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
  Science (New York, N.Y.). Jan, 2004  |   Pubmed ID: 14739459
• Subcellular Fractionation of Tissue Culture Cells
  Current Protocols in Immunology. Nov, 2003  |   Pubmed ID: 18432914
• The Trans-membrane Protein P25 Forms Highly Specialized Domains That Regulate Membrane Composition and Dynamics
  Journal of Cell Science. Dec, 2003  |   Pubmed ID: 14600267
• Lipids in Endocytic Membrane Transport and Sorting
  Current Opinion in Cell Biology. Aug, 2003  |   Pubmed ID: 12892777
• Annexin II Regulates Multivesicular Endosome Biogenesis in the Degradation Pathway of Animal Cells
  The EMBO Journal. Jul, 2003  |   Pubmed ID: 12839987
• Sliding Doors: Clathrin-coated Pits or Caveolae?
  Nature Cell Biology. May, 2003  |   Pubmed ID: 12724770
• Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-kinase
  Molecular and Cellular Biology. Apr, 2003  |   Pubmed ID: 12640132
• Signaling from the Far Side
  Molecular Cell. Dec, 2002  |   Pubmed ID: 12503999
• Oiling the Wheels of the Endocytic Pathway
  Trends in Cell Biology. Jul, 2002  |   Pubmed ID: 12185843
• Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes
  Current Biology : CB. Jun, 2002  |   Pubmed ID: 12123571
• Separation and Characterization of Late Endosomal Membrane Domains
  The Journal of Biological Chemistry. Aug, 2002  |   Pubmed ID: 12065580
• Late Endosome Motility Depends on Lipids Via the Small GTPase Rab7
  The EMBO Journal. Mar, 2002  |   Pubmed ID: 11889035