Jeffrey D. Varner Robert Frederick Smith School of Chemical and Biomolecular Engineering Cornell University Biography Publications Institution JoVE Articles Jeffrey D. Varner has not added a biography. If you are Jeffrey D. Varner and would like to personalize this page please email our Author Liaison for assistance. Publications Improving Designer Glycan Production in Through Model-guided Metabolic Engineering Metabolic Engineering Communications. Dec, 2019 | Pubmed ID: 31008057 Analysis of the Role of Thrombomodulin in All-trans Retinoic Acid Treatment of Coagulation Disorders in Cancer Patients Theoretical Biology & Medical Modelling. 02, 2019 | Pubmed ID: 30764845 Retinoic Acid and 6-formylindolo(3,2-b)carbazole (FICZ) Combination Therapy Reveals Putative Targets for Enhancing Response in Non-APL AML Leukemia & Lymphoma. Jul, 2019 | Pubmed ID: 30570341 Multi-scale Computational Study of the Warburg Effect, Reverse Warburg Effect and Glutamine Addiction in Solid Tumors PLoS Computational Biology. 12, 2018 | Pubmed ID: 30532226 Dynamic Optimization with Particle Swarms (DOPS): a Meta-heuristic for Parameter Estimation in Biochemical Models BMC Systems Biology. 10, 2018 | Pubmed ID: 30314484 Sequence Specific Modeling of E. Coli Cell-Free Protein Synthesis ACS Synthetic Biology. 08, 2018 | Pubmed ID: 29944340 Src Family Kinase Inhibitor Bosutinib Enhances Retinoic Acid-induced Differentiation of HL-60 Leukemia Cells Leukemia & Lymphoma. 12, 2018 | Pubmed ID: 29569971 Potential for Subsets of Wt-NPM1 Primary AML Blasts to Respond to Retinoic Acid Treatment Oncotarget. Jan, 2018 | Pubmed ID: 29423110 Reduced Order Modeling and Analysis of the Human Complement System PloS One. 2017 | Pubmed ID: 29155837 An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program Scientific Reports. 10, 2017 | Pubmed ID: 29085021 JuPOETs: a Constrained Multiobjective Optimization Approach to Estimate Biochemical Model Ensembles in the Julia Programming Language BMC Systems Biology. 01, 2017 | Pubmed ID: 28122561 Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1 PLoS Computational Biology. Dec, 2016 | Pubmed ID: 28027307 Induced Myelomonocytic Differentiation in Leukemia Cells is Accompanied by Noncanonical Transcription Factor Expression FEBS Open Bio. 2015 | Pubmed ID: 26566473 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells PloS One. 2015 | Pubmed ID: 26287494 Generating Effective Models and Parameters for RNA Genetic Circuits ACS Synthetic Biology. Aug, 2015 | Pubmed ID: 26046393 GW5074 and PP2 Kinase Inhibitors Implicate Nontraditional C-Raf and Lyn Function As Drivers of Retinoic Acid-induced Maturation Cellular Signalling. Aug, 2015 | Pubmed ID: 25817574 Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts PloS One. 2014 | Pubmed ID: 24922062 Ubiquibodies, Synthetic E3 Ubiquitin Ligases Endowed with Unnatural Substrate Specificity for Targeted Protein Silencing The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474696 Physicochemical Regulation of Endothelial Sprouting in a 3D Microfluidic Angiogenesis Model Journal of Biomedical Materials Research. Part A. Oct, 2013 | Pubmed ID: 23559519 The Src-family Kinase Inhibitor PP2 Rescues Inducible Differentiation Events in Emergent Retinoic Acid-resistant Myeloblastic Leukemia Cells PloS One. 2013 | Pubmed ID: 23554907 Hierarchical Approaches for Systems Modeling in Cardiac Development Wiley Interdisciplinary Reviews. Systems Biology and Medicine. May-Jun, 2013 | Pubmed ID: 23463736 Multiscale Models of Breast Cancer Progression Annals of Biomedical Engineering. Nov, 2012 | Pubmed ID: 23008097 Computational Modeling and Analysis of Insulin Induced Eukaryotic Translation Initiation PLoS Computational Biology. Nov, 2011 | Pubmed ID: 22102801 A Review of the Mammalian Unfolded Protein Response Biotechnology and Bioengineering. Dec, 2011 | Pubmed ID: 21809331 Interferon Regulatory Factor-1 Binds C-Cbl, Enhances Mitogen Activated Protein Kinase Signaling and Promotes Retinoic Acid-induced Differentiation of HL-60 Human Myelo-monoblastic Leukemia Cells Leukemia & Lymphoma. Dec, 2011 | Pubmed ID: 21740303 Modeling and Analysis of Retinoic Acid Induced Differentiation of Uncommitted Precursor Cells Integrative Biology : Quantitative Biosciences from Nano to Macro. May, 2011 | Pubmed ID: 21437295 Ensembles of Uncertain Mathematical Models Can Identify Network Response to Therapeutic Interventions Molecular BioSystems. Nov, 2010 | Pubmed ID: 20844798 Ensembles of Signal Transduction Models Using Pareto Optimal Ensemble Techniques (POETs) Biotechnology Journal. Jul, 2010 | Pubmed ID: 20665647 Arsenic Trioxide Cooperates with All Trans Retinoic Acid to Enhance Mitogen-activated Protein Kinase Activation and Differentiation in PML-RARalpha Negative Human Myeloblastic Leukemia Cells Leukemia & Lymphoma. Sep, 2010 | Pubmed ID: 20615082 Analysis of the Molecular Networks in Androgen Dependent and Independent Prostate Cancer Revealed Fragile and Robust Subsystems PloS One. Jan, 2010 | Pubmed ID: 20126616 Engineering the Spatial Organization of Metabolic Enzymes: Mimicking Nature's Synergy Current Opinion in Biotechnology. Oct, 2008 | Pubmed ID: 18725290 A Test of Highly Optimized Tolerance Reveals Fragile Cell-cycle Mechanisms Are Molecular Targets in Clinical Cancer Trials PloS One. Apr, 2008 | Pubmed ID: 18431497 Computationally Derived Points of Fragility of a Human Cascade Are Consistent with Current Therapeutic Strategies PLoS Computational Biology. Jul, 2007 | Pubmed ID: 17658944 Stochastic Reaction-diffusion Simulation of Enzyme Compartmentalization Reveals Improved Catalytic Efficiency for a Synthetic Metabolic Pathway Metabolic Engineering. Jul, 2007 | Pubmed ID: 17601761 Systems Biology and the Mathematical Modelling of Antibody-directed Enzyme Prodrug Therapy (ADEPT) Systems Biology. Dec, 2005 | Pubmed ID: 16986273 Абсолютная количественная количественная количественная количественная метания белка без клеток путем обратной фазы жидкой хроматографии-масс-спектрометрии Michael Vilkhovoy1, David Dai1, Sandra Vadhin*1, Abhinav Adhikari*1, Jeffrey D. Varner1 1Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University JoVE 60329 Biochemistry
Абсолютная количественная количественная количественная количественная метания белка без клеток путем обратной фазы жидкой хроматографии-масс-спектрометрии Michael Vilkhovoy1, David Dai1, Sandra Vadhin*1, Abhinav Adhikari*1, Jeffrey D. Varner1 1Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University JoVE 60329 Biochemistry