Jen-Tsan Chi

Publications

• A Comprehensive Joint Analysis of the Long and Short RNA Transcriptomes of Human Erythrocytes
  BMC Genomics. 2015  |   Pubmed ID: 26573221
• FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target
  Radiation Research. Nov, 2015  |   Pubmed ID: 26488758
• ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 Via α-ketoglutarate
  PLoS Genetics. Oct, 2015  |   Pubmed ID: 26452058
• Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition
  Journal of Medicinal Chemistry. Oct, 2015  |   Pubmed ID: 26394152
• A Paclitaxel-loaded Recombinant Polypeptide Nanoparticle Outperforms Abraxane in Multiple Murine Cancer Models
  Nature Communications. 2015  |   Pubmed ID: 26239362
• Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
  Cell Reports. Jul, 2015  |   Pubmed ID: 26119730
• Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers
  International Journal of Radiation Oncology, Biology, Physics. Jul, 2015  |   Pubmed ID: 26104938
• Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis
  PloS One. 2015  |   Pubmed ID: 26075887
• Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2015  |   Pubmed ID: 26071485
• E2F1-Mediated Induction of NFYB Attenuates Apoptosis Via Joint Regulation of a Pro-Survival Transcriptional Program
  PloS One. 2015  |   Pubmed ID: 26039627
• Comprehensive Profiling of Amino Acid Response Uncovers Unique Methionine-deprived Response Dependent on Intact Creatine Biosynthesis
  PLoS Genetics. Apr, 2015  |   Pubmed ID: 25849282
• Alternative Fuels for Cancer Cells
  Cancer Journal (Sudbury, Mass.). Mar-Apr, 2015  |   Pubmed ID: 25815843
• Whole Blood Gene Expression Profiles Distinguish Clinical Phenotypes of Venous Thromboembolism
  Thrombosis Research. Apr, 2015  |   Pubmed ID: 25684211
• Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
  Molecular Cancer Therapeutics. Mar, 2015  |   Pubmed ID: 25589495
• An Unexpected Alliance Between Stress Responses to Drive Oncogenesis
  Breast Cancer Research : BCR. 2014  |   Pubmed ID: 25927911
• Utilization of the Eμ-Myc Mouse to Model Heterogeneity of Therapeutic Response
  Molecular Cancer Therapeutics. Dec, 2014  |   Pubmed ID: 25349303
• Glycolysis-dependent Histone Deacetylase 4 Degradation Regulates Inflammatory Cytokine Production
  Molecular Biology of the Cell. Nov, 2014  |   Pubmed ID: 25187650
• A Joint Analysis of Metabolomics and Genetics of Breast Cancer
  Breast Cancer Research : BCR. 2014  |   Pubmed ID: 25091696
• Alveolar Rhabdomyosarcoma-associated PAX3-FOXO1 Promotes Tumorigenesis Via Hippo Pathway Suppression
  The Journal of Clinical Investigation. Jan, 2014  |   Pubmed ID: 24334454
• Acidosis Induces Reprogramming of Cellular Metabolism to Mitigate Oxidative Stress
  Cancer & Metabolism. 2013  |   Pubmed ID: 24359630
• Catabolism of Exogenous Lactate Reveals It As a Legitimate Metabolic Substrate in Breast Cancer
  PloS One. 2013  |   Pubmed ID: 24069390
• Understanding the Tumor Microenvironment and Radioresistance by Combining Functional Imaging with Global Gene Expression
  Seminars in Radiation Oncology. Oct, 2013  |   Pubmed ID: 24012344
• Aspirin Exposure Reveals Novel Genes Associated with Platelet Function and Cardiovascular Events
  Journal of the American College of Cardiology. Oct, 2013  |   Pubmed ID: 23831034
• Acidosis Activation of the Proton-sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis
  PloS One. 2013  |   Pubmed ID: 23613998
• Iron-responsive MiR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin
  PLoS Genetics. Apr, 2013  |   Pubmed ID: 23593016
• Global Identification of MLL2-targeted Loci Reveals MLL2's Role in Diverse Signaling Pathways
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012  |   Pubmed ID: 23045699
• Associations Between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans
  Journal of Cancer Epidemiology. 2012  |   Pubmed ID: 22927849
• Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium Falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance
  Cell Host & Microbe. Aug, 2012  |   Pubmed ID: 22901539
• A Heterozygous IDH1R132H/WT Mutation Induces Genome-wide Alterations in DNA Methylation
  Genome Research. Dec, 2012  |   Pubmed ID: 22899282
• Time-dependent Changes in Non-COX-1-dependent Platelet Function with Daily Aspirin Therapy
  Journal of Thrombosis and Thrombolysis. Apr, 2012  |   Pubmed ID: 22294277
• Functional Interaction Between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
  Cancer Research. Jan, 2012  |   Pubmed ID: 22135092
• Glutamine Synthetase is a Genetic Determinant of Cell Type-specific Glutamine Independence in Breast Epithelia
  PLoS Genetics. Aug, 2011  |   Pubmed ID: 21852960
• Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality
  Science Translational Medicine. Aug, 2011  |   Pubmed ID: 21813754
• Whole Blood Gene Expression Analyses in Patients with Single Versus Recurrent Venous Thromboembolism
  Thrombosis Research. Dec, 2011  |   Pubmed ID: 21737128
• Analysis of Tumor Environmental Response and Oncogenic Pathway Activation Identifies Distinct Basal and Luminal Features in HER2-related Breast Tumor Subtypes
  Breast Cancer Research : BCR. 2011  |   Pubmed ID: 21672245
• Polysome Profiling of the Malaria Parasite Plasmodium Falciparum
  Molecular and Biochemical Parasitology. Sep, 2011  |   Pubmed ID: 21605599
• Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2011  |   Pubmed ID: 21292819
• Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP Through MondoA
  PLoS Genetics. Sep, 2010  |   Pubmed ID: 20844768
• Isolation and Characterization of MicroRNAs of Human Mature Erythrocytes
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20827535
• Latent Factor Analysis to Discover Pathway-associated Putative Segmental Aneuploidies in Human Cancers
  PLoS Computational Biology. 2010  |   Pubmed ID: 20824128
• MicroRNA MiR-144 Modulates Oxidative Stress Tolerance and Associates with Anemia Severity in Sickle Cell Disease
  Blood. Nov, 2010  |   Pubmed ID: 20709907
• Pleiotrophin Regulates the Expansion and Regeneration of Hematopoietic Stem Cells
  Nature Medicine. Apr, 2010  |   Pubmed ID: 20305662
• AN INTEGRATIVE ANALYSIS OF CANCER GENE EXPRESSION STUDIES USING BAYESIAN LATENT FACTOR MODELING
  The Annals of Applied Statistics. 2009  |   Pubmed ID: 20953268
• P38gamma Mitogen-activated Protein Kinase is a Key Regulator in Skeletal Muscle Metabolic Adaptation in Mice
  PloS One. 2009  |   Pubmed ID: 19936205
• Tumor Vasculature is Regulated by PHD2-mediated Angiogenesis and Bone Marrow-derived Cell Recruitment
  Cancer Cell. Jun, 2009  |   Pubmed ID: 19477431
• Cross-study Projections of Genomic Biomarkers: an Evaluation in Cancer Genomics
  PloS One. 2009  |   Pubmed ID: 19225561
• The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers
  PLoS Genetics. Dec, 2008  |   Pubmed ID: 19057672
• Combining Biological Gene Expression Signatures in Predicting Outcome in Breast Cancer: An Alternative to Supervised Classification
  European Journal of Cancer (Oxford, England : 1990). Oct, 2008  |   Pubmed ID: 18715778
• The Genomic Analysis of Erythrocyte MicroRNA Expression in Sickle Cell Diseases
  PloS One. 2008  |   Pubmed ID: 18523662
• Modeling Cancer Progression Via Pathway Dependencies
  PLoS Computational Biology. Feb, 2008  |   Pubmed ID: 18282083
• A Viral MicroRNA Functions As an Orthologue of Cellular MiR-155
  Nature. Dec, 2007  |   Pubmed ID: 18075594
• Gene Expression Programs of Human Smooth Muscle Cells: Tissue-specific Differentiation and Prognostic Significance in Breast Cancers
  PLoS Genetics. Sep, 2007  |   Pubmed ID: 17907811
• The Potential Role of Intrinsic Hypoxia Markers As Prognostic Variables in Cancer
  Antioxidants & Redox Signaling. Aug, 2007  |   Pubmed ID: 17571959
• Minimizing Off-target Effects by Using Diced SiRNAs for RNA Interference
  Journal of RNAi and Gene Silencing : an International Journal of RNA and Gene Targeting Research. 2006  |   Pubmed ID: 19771225
• Predicting a Local Recurrence After Breast-conserving Therapy by Gene Expression Profiling
  Breast Cancer Research : BCR. 2006  |   Pubmed ID: 17069664
• Lysyl Oxidase is Essential for Hypoxia-induced Metastasis
  Nature. Apr, 2006  |   Pubmed ID: 16642001
• Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
  PLoS Medicine. Mar, 2006  |   Pubmed ID: 16417408
• Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities Between Tumors and Wounds
  PLoS Biology. Feb, 2004  |   Pubmed ID: 14737219
• Systemic and Cell Type-specific Gene Expression Patterns in Scleroderma Skin
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003  |   Pubmed ID: 14530402
• Endothelial Cell Diversity Revealed by Global Expression Profiling
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003  |   Pubmed ID: 12963823
• Genomewide View of Gene Silencing by Small Interfering RNAs
  Proceedings of the National Academy of Sciences of the United States of America. May, 2003  |   Pubmed ID: 12730368
• Diversity, Topographic Differentiation, and Positional Memory in Human Fibroblasts
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002  |   Pubmed ID: 12297622
• Comprehensive Analysis of the Gene Expression Profiles in Human Gastric Cancer Cell Lines
  Oncogene. Sep, 2002  |   Pubmed ID: 12226758