Jeremy C. Simpson Cell Screening Laboratory, UCD School of Biology and Environmental Science University College Dublin Biography Publications Institution JoVE Articles Jeremy C. Simpson has not added a biography. If you are Jeremy C. Simpson and would like to personalize this page please email our Author Liaison for assistance. Publications Cell3: a New Vision for Study of the Endomembrane System in Mammalian Cells Bioscience Reports. Dec, 2021 | Pubmed ID: 34874399 Cell3: A New Vision for Study of the Endomembrane System in Mammalian Cells Bioscience Reports. Nov, 2021 | Pubmed ID: 34793591 2D-GolgiTrack-a Semi-automated Tracking System to Quantify Morphological Changes and Dynamics of the Golgi Apparatus and Golgi-derived Membrane Tubules Medical & Biological Engineering & Computing. Nov, 2021 | Pubmed ID: 34783979 Multiparametric Nanoparticle-induced Toxicity Readouts with Single Cell Resolution in HepG2 Multicellular Tumour Spheroids Nanoscale. Oct, 2021 | Pubmed ID: 34661590 A Novel Automated Image Analysis Pipeline for Quantifying Morphological Changes to the Endoplasmic Reticulum in Cultured Human Cells BMC Bioinformatics. Sep, 2021 | Pubmed ID: 34496765 Inactivation Efficacy of Atmospheric Air Plasma and Airborne Acoustic Ultrasound Against Bacterial Biofilms Scientific Reports. 01, 2021 | Pubmed ID: 33504900 A Novel High-content Screening Approach for the Elucidation of C. Jejuni Biofilm Composition and Integrity BMC Microbiology. 01, 2021 | Pubmed ID: 33397288 Emerging Roles for Rho GTPases Operating at the Golgi Complex Small GTPases. Sep-Nov, 2021 | Pubmed ID: 32881632 Antimicrobial Effects of Airborne Acoustic Ultrasound and Plasma Activated Water from Cold and Thermal Plasma Systems on Biofilms Scientific Reports. 10, 2020 | Pubmed ID: 33057158 RNA Interference Screening Identifies Novel Roles for RhoBTB1 and RhoBTB3 in Membrane Trafficking Events in Mammalian Cells Cells. 04, 2020 | Pubmed ID: 32354068 Modification of the Mammalian Endomembrane System in Healthy and Diseased Cells International Journal of Molecular Sciences. Mar, 2020 | Pubmed ID: 32244909 Characterisation of GLUT4 Trafficking in HeLa Cells: Comparable Kinetics and Orthologous Trafficking Mechanisms to 3T3-L1 Adipocytes PeerJ. 2020 | Pubmed ID: 32185116 SCLpred-EMS: Subcellular Localization Prediction of Endomembrane System and Secretory Pathway Proteins by Deep N-to-1 Convolutional Neural Networks Bioinformatics (Oxford, England). 06, 2020 | Pubmed ID: 32142105 Precise Targeting of MiRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. 04, 2020 | Pubmed ID: 32059764 Acquisition of Fluoroquinolone Resistance Leads to Increased Biofilm Formation and Pathogenicity in Campylobacter Jejuni Scientific Reports. 12, 2019 | Pubmed ID: 31796849 NeurodegenERation: The Central Role for ER Contacts in Neuronal Function and Axonopathy, Lessons From Hereditary Spastic Paraplegias and Related Diseases Frontiers in Neuroscience. 2019 | Pubmed ID: 31680803 Rab35 Controls Cilium Length, Function and Membrane Composition EMBO Reports. 10, 2019 | Pubmed ID: 31432619 The Challenges and Possibilities of Extracellular Vesicles As Therapeutic Vehicles European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Nov, 2019 | Pubmed ID: 31419585 Multitasking Rab Proteins in Autophagy and Membrane Trafficking: A Focus on Rab33b International Journal of Molecular Sciences. Aug, 2019 | Pubmed ID: 31408960 A High-Throughput Automated Confocal Microscopy Platform for Quantitative Phenotyping of Nanoparticle Uptake and Transport in Spheroids Small (Weinheim an Der Bergstrasse, Germany). 09, 2019 | Pubmed ID: 31334922 Computational and Experimental Analysis of Bioactive Peptide Linear Motifs in the Integrin Adhesome PloS One. 2019 | Pubmed ID: 30689642 Rapid Growth Cone Uptake and Dynein-Mediated Axonal Retrograde Transport of Negatively Charged Nanoparticles in Neurons Is Dependent on Size and Cell Type Small (Weinheim an Der Bergstrasse, Germany). 01, 2019 | Pubmed ID: 30565853 Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells Molecular Pharmaceutics. 05, 2018 | Pubmed ID: 29590755 Heritable Skeletal Disorders Arising from Defects in Processing and Transport of Type I Procollagen from the ER: Perspectives on Possible Therapeutic Approaches Handbook of Experimental Pharmacology. 2018 | Pubmed ID: 29071510 Roles for the VCP Co-factors Npl4 and Ufd1 in Neuronal Function in Drosophila Melanogaster Journal of Genetics and Genomics = Yi Chuan Xue Bao. Oct, 2017 | Pubmed ID: 29037990 Characterization of Carboxylate Nanoparticle Adhesion with the Fungal Pathogen Candida Albicans Nanoscale. Oct, 2017 | Pubmed ID: 29019498 Functional Characterisation of the YIPF Protein Family in Mammalian Cells Histochemistry and Cell Biology. Apr, 2017 | Pubmed ID: 27999994 Systematic Functional Analysis of the Ras GTPase Family Unveils a Conserved Network Required for Anterograde Protein Trafficking Proteomics. 01, 2017 | Pubmed ID: 27957805 Rho GTPases Operating at the Golgi Complex: Implications for Membrane Traffic and Cancer Biology Tissue & Cell. Apr, 2017 | Pubmed ID: 27720426 Genome-Wide SiRNA Screening Using Forward Transfection: Identification of Modulators of Membrane Trafficking in Mammalian Cells Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27581283 A Systematic High-Content Screening Microscopy Approach Reveals Key Roles for Rab33b, OATL1 and Myo6 in Nanoparticle Trafficking in HeLa Cells Scientific Reports. 07, 2016 | Pubmed ID: 27374232 Lysosome Triggered Near-infrared Fluorescence Imaging of Cellular Trafficking Processes in Real Time Nature Communications. Mar, 2016 | Pubmed ID: 26927507 Implementation of the Rank-Weighted Co-localization (RWC) Algorithm in Multiple Image Analysis Platforms for Quantitative Analysis of Microscopy Images Source Code for Biology and Medicine. 2016 | Pubmed ID: 26884809 High-content Analysis of Rab Protein Function at the ER-Golgi Interface Bioarchitecture. 2015 | Pubmed ID: 26693811 A High-content Screening Microscopy Approach to Dissect the Role of Rab Proteins in Golgi-to-ER Retrograde Trafficking Journal of Cell Science. Jul, 2015 | Pubmed ID: 25999475 High-content Analysis for Drug Delivery and Nanoparticle Applications Drug Discovery Today. Aug, 2015 | Pubmed ID: 25908578 A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways Molecular & Cellular Proteomics : MCP. May, 2015 | Pubmed ID: 25759509 Hydroxyapatite and Fluorapatite Coatings on Dental Screws: Effects of Blast Coating Process and Biological Response Journal of Materials Science. Materials in Medicine. Jan, 2015 | Pubmed ID: 25578701 Biocompatibility of Ferroelectric Lithium Niobate and the Influence of Polarization Charge on Osteoblast Proliferation and Function Journal of Biomedical Materials Research. Part A. Aug, 2015 | Pubmed ID: 25504748 Trajectory-based Co-localization Measures for Nanoparticle-cell Interaction Studies Small (Weinheim an Der Bergstrasse, Germany). May, 2015 | Pubmed ID: 25504742 The Trials and Tubule-ations of Rab6 Involvement in Golgi-to-ER Retrograde Transport Biochemical Society Transactions. Oct, 2014 | Pubmed ID: 25233431 HGF Induces Epithelial-to-mesenchymal Transition by Modulating the Mammalian Hippo/MST2 and ISG15 Pathways Journal of Proteome Research. Jun, 2014 | Pubmed ID: 24766643 Endoplasmic Reticulum Stress-activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 to Modulate Chemoresistance Molecular and Cellular Biology. May, 2014 | Pubmed ID: 24636989 RNAi-mediated Inhibition of Apoptosis Fails to Prevent Cationic Nanoparticle-induced Cell Death in Cultured Cells Nanomedicine (London, England). Aug, 2014 | Pubmed ID: 24359549 Actin in Action: Imaging Approaches to Study Cytoskeleton Structure and Function Cells. Nov, 2013 | Pubmed ID: 24709877 High-content Screening and Analysis of the Golgi Complex Methods in Cell Biology. 2013 | Pubmed ID: 24295313 Time Resolved Study of Cell Death Mechanisms Induced by Amine-modified Polystyrene Nanoparticles Nanoscale. Nov, 2013 | Pubmed ID: 24108393 Human Diseases Associated with Form and Function of the Golgi Complex International Journal of Molecular Sciences. Sep, 2013 | Pubmed ID: 24025425 A Real-time Impedance Based Method to Assess Rhodococcus Equi Virulence PloS One. 2013 | Pubmed ID: 23555995 Anti-prion Drug MPPIg5 Inhibits PrP(C) Conversion to PrP(Sc) PloS One. 2013 | Pubmed ID: 23383136 Quantitative Image Analysis Approaches for Probing Rab GTPase Localization and Function in Mammalian Cells Biochemical Society Transactions. Dec, 2012 | Pubmed ID: 23176486 Quantifying Size-dependent Interactions Between Fluorescently Labeled Polystyrene Nanoparticles and Mammalian Cells Journal of Nanobiotechnology. Sep, 2012 | Pubmed ID: 23006133 Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A PloS One. 2012 | Pubmed ID: 22973456 A Method for Improved Clustering and Classification of Microscopy Images Using Quantitative Co-localization Coefficients BMC Research Notes. Jun, 2012 | Pubmed ID: 22681635 Genome-wide RNAi Screening Identifies Human Proteins with a Regulatory Function in the Early Secretory Pathway Nature Cell Biology. Jun, 2012 | Pubmed ID: 22660414 High-speed Imaging of Rab Family Small GTPases Reveals Rare Events in Nanoparticle Trafficking in Living Cells ACS Nano. Feb, 2012 | Pubmed ID: 22276691 Dual Channel Rank-based Intensity Weighting for Quantitative Co-localization of Microscopy Images BMC Bioinformatics. Oct, 2011 | Pubmed ID: 22017789 Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation Molecular & Cellular Proteomics : MCP. Oct, 2011 | Pubmed ID: 21778410 Cationic Nanoparticles Induce Caspase 3-, 7- and 9-mediated Cytotoxicity in a Human Astrocytoma Cell Line Nanotoxicology. Dec, 2011 | Pubmed ID: 21142842 Role of Varp, a Rab21 Exchange Factor and TI-VAMP/VAMP7 Partner, in Neurite Growth EMBO Reports. Oct, 2009 | Pubmed ID: 19745841 Screening the Secretion Machinery: High Throughput Imaging Approaches to Elucidate the Secretory Pathway Seminars in Cell & Developmental Biology. Oct, 2009 | Pubmed ID: 19660568 En robust metode for storskala produksjon av sfæroider for screening- og analyseapplikasjoner med høyt innhold Alannah S. Chalkley1, Margaritha M. Mysior1, Jeremy C. Simpson1 1Cell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin JoVE 63436 Biology
En robust metode for storskala produksjon av sfæroider for screening- og analyseapplikasjoner med høyt innhold Alannah S. Chalkley1, Margaritha M. Mysior1, Jeremy C. Simpson1 1Cell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin JoVE 63436 Biology