John P. Kirwan Integrated Physiology and Molecular Medicine Laboratory Pennington Biomedical Research Center Biography Publications Institution JoVE Articles John P. Kirwan has not added a biography. If you are John P. Kirwan and would like to personalize this page please email our Author Liaison for assistance. Publications CRISPR/Cas9-engineered Drosophila Knock-in Models to Study VCP Diseases Disease Models & Mechanisms. Jul, 2021 | Pubmed ID: 34296742 Constraints of Weight Loss As a Marker of Bariatric Surgery Success: An Exploratory Study Frontiers in Physiology. 2021 | Pubmed ID: 34177607 CRISPR/Cas9-engineered Drosophila Knock-in Models to Study VCP Diseases Disease Models & Mechanisms. Jul, 2021 | Pubmed ID: 34160014 Patient Reported Outcomes After Metabolic Surgery Versus Medical Therapy for Diabetes: Insights from the STAMPEDE Randomized Trial Annals of Surgery. Jun, 2021 | Pubmed ID: 34132694 Exercise Is Key to Sustaining Metabolic Gains After Bariatric Surgery Exercise and Sport Sciences Reviews. Jul, 2021 | Pubmed ID: 34112745 Lipids Activate Skeletal Muscle Mitochondrial Fission and Quality Control Networks to Induce Insulin Resistance in Humans Metabolism: Clinical and Experimental. Aug, 2021 | Pubmed ID: 34090870 Foregut Exclusion Enhances Incretin and Insulin Secretion After Roux-en-Y Gastric Bypass in Adults with Type 2 Diabetes The Journal of Clinical Endocrinology and Metabolism. Apr, 2021 | Pubmed ID: 33870426 Resting Energy Expenditure Is Elevated in Asthma Nutrients. Mar, 2021 | Pubmed ID: 33805960 Roux-en-Y Gastric Bypass Restores Islet Function and Morphology Independent of Body Weight in ZDF Rats American Journal of Physiology. Endocrinology and Metabolism. Jan, 2021 | Pubmed ID: 33427046 Exercise Enhances the Effect of Bariatric Surgery in Markers of Cardiac Autonomic Function Obesity Surgery. 03, 2021 | Pubmed ID: 33111247 Adiposity, Physical Function, and Their Associations With Insulin Resistance, Inflammation, and Adipokines in CKD American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 01, 2021 | Pubmed ID: 32798563 Metabolic Effects of Duodenojejunal Bypass Surgery in a Rat Model of Type 1 Diabetes Surgical Endoscopy. Jun, 2021 | Pubmed ID: 32607903 Sleep Extension: A Potential Target for Obesity Treatment Current Diabetes Reports. 12, 2020 | Pubmed ID: 33275183 Outpatient Screening of Health Status Among Postbariatric Patients During the COVID-19 Pandemic in Sao Paulo, Brazil Obesity (Silver Spring, Md.). 12, 2020 | Pubmed ID: 32881292 Obesity, the Most Common Comorbidity in SARS-CoV-2: is Leptin the Link? International Journal of Obesity (2005). 09, 2020 | Pubmed ID: 32647360 Mitochondrial Utilization of Competing Fuels Is Altered in Insulin Resistant Skeletal Muscle of Non-obese Rats (Goto-Kakizaki) Frontiers in Physiology. 2020 | Pubmed ID: 32612543 Exercise Plus Caloric Restriction Lowers Soluble RAGE in Adults with Chronic Kidney Disease Obesity Science & Practice. Jun, 2020 | Pubmed ID: 32523720 BAM15-mediated Mitochondrial Uncoupling Protects Against Obesity and Improves Glycemic Control EMBO Molecular Medicine. 07, 2020 | Pubmed ID: 32519812 Effects of Gastric Bypass Surgery on Expression of Glucose Transporters and Fibrotic Biomarkers in Kidney of Diabetic Fatty Rats Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. Sep, 2020 | Pubmed ID: 32505735 Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes Medicine and Science in Sports and Exercise. 10, 2020 | Pubmed ID: 32496736 Exercise-Induced Increases in Insulin Sensitivity After Bariatric Surgery Are Mediated By Muscle Extracellular Matrix Remodeling Diabetes. 08, 2020 | Pubmed ID: 32409493 β-Hydroxybutyrate is Reduced in Humans with Obesity-related NAFLD and Displays a Dose-dependent Effect on Skeletal Muscle Mitochondrial Respiration in Vitro American Journal of Physiology. Endocrinology and Metabolism. 07, 2020 | Pubmed ID: 32396388 Rationale and Study Design for Lifestyle Intervention in Preparation for Pregnancy (LIPP): A Randomized Controlled Trial Contemporary Clinical Trials. 07, 2020 | Pubmed ID: 32389808 Joint International Consensus Statement for Ending Stigma of Obesity Nature Medicine. 04, 2020 | Pubmed ID: 32127716 Plasma Metabolomic Profile in Chronic Thromboembolic Pulmonary Hypertension Pulmonary Circulation. Jan-Mar, 2020 | Pubmed ID: 32110382 Lipids and Ketones Dominate Metabolism at the Expense of Glucose Control in Pulmonary Arterial Hypertension: a Hyperglycaemic Clamp and Metabolomics Study The European Respiratory Journal. 04, 2020 | Pubmed ID: 32108049 A Randomized Controlled Trial to Reduce Sedentary Time in Rheumatoid Arthritis: Protocol and Rationale of the Take a STAND for Health Study Trials. Feb, 2020 | Pubmed ID: 32051025 Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD Medicine and Science in Sports and Exercise. 07, 2020 | Pubmed ID: 32028458 UCC118 Supplementation Reduces Exercise-induced Gastrointestinal Permeability and Remodels the Gut Microbiome in Healthy Humans Physiological Reports. 11, 2019 | Pubmed ID: 31758610 Non-invasive Assessment of Hepatic Lipid Subspecies Matched with Non-alcoholic Fatty Liver Disease Phenotype Nutrition, Metabolism, and Cardiovascular Diseases : NMCD. 11, 2019 | Pubmed ID: 31371265 Exercise Mitigates Bone Loss in Women With Severe Obesity After Roux-en-Y Gastric Bypass: A Randomized Controlled Trial The Journal of Clinical Endocrinology and Metabolism. 10, 2019 | Pubmed ID: 31322672 Skeletal Muscle Nur77 and NOR1 Insulin Responsiveness is Blunted in Obesity and Type 2 Diabetes but Improved After Exercise Training Physiological Reports. 03, 2019 | Pubmed ID: 30912283 Exercise Training Promotes a GDF15-associated Reduction in Fat Mass in Older Adults with Obesity American Journal of Physiology. Endocrinology and Metabolism. 05, 2019 | Pubmed ID: 30860878 Gastric Bypass Surgery Improves the Skeletal Muscle Ceramide/S1P Ratio and Upregulates the AMPK/ SIRT1/ PGC-1α Pathway in Zucker Diabetic Fatty Rats Obesity Surgery. 07, 2019 | Pubmed ID: 30809769 A Whole-Grain Diet Increases Glucose-Stimulated Insulin Secretion Independent of Gut Hormones in Adults at Risk for Type 2 Diabetes Molecular Nutrition & Food Research. 04, 2019 | Pubmed ID: 30763457 Medical Marijuana-an Obesity Problem or Opportunity? International Journal of Obesity (2005). 04, 2019 | Pubmed ID: 30755697 The Historical Context and Scientific Legacy of John O. Holloszy Journal of Applied Physiology (Bethesda, Md. : 1985). 08, 2019 | Pubmed ID: 30730811 Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults Nutrients. Jan, 2019 | Pubmed ID: 30654453 Exercise-induced Improvements in Glucose Effectiveness Are blunted by a High Glycemic Diet in Adults with Prediabetes Acta Diabetologica. Feb, 2019 | Pubmed ID: 30612202 Exercise Training Remodels Human Skeletal Muscle Mitochondrial Fission and Fusion Machinery Towards a Pro-elongation Phenotype Acta Physiologica (Oxford, England). 04, 2019 | Pubmed ID: 30408342 Mitochondrial Dynamics in Skeletal Muscle Insulin Resistance and Type 2 Diabetes Translational Research : the Journal of Laboratory and Clinical Medicine. 12, 2018 | Pubmed ID: 30153426 Mechanisms Responsible for Metabolic Improvements of Bariatric Surgeries Diabetes. 06, 2018 | Pubmed ID: 29784652 Functional High-intensity Exercise Training Ameliorates Insulin Resistance and Cardiometabolic Risk Factors in Type 2 Diabetes Experimental Physiology. 07, 2018 | Pubmed ID: 29766601 切除された固形腫瘍均質物のミトコンドリア機能の分析的決定 Elizabeth R. M. Zunica1,2,3, Christopher L. Axelrod1, L. Anne Gilmore2,4, John P. Kirwan1,3 1Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, 2Clinical Oncology and Metabolism, Pennington Biomedical Research Center, 3Department of Nutrition, Case Western Reserve University, 4Department of Clinical Nutrition, University of Texas Southwestern Medical Center JoVE 62875 Cancer Research
切除された固形腫瘍均質物のミトコンドリア機能の分析的決定 Elizabeth R. M. Zunica1,2,3, Christopher L. Axelrod1, L. Anne Gilmore2,4, John P. Kirwan1,3 1Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, 2Clinical Oncology and Metabolism, Pennington Biomedical Research Center, 3Department of Nutrition, Case Western Reserve University, 4Department of Clinical Nutrition, University of Texas Southwestern Medical Center JoVE 62875 Cancer Research
