Jonna Frasor

Publications

• Full Antagonism of the Estrogen Receptor Without a Prototypical Ligand Side Chain
  Nature Chemical Biology. Jan, 2017  |   Pubmed ID: 27870835
• Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of P65 Protein
  The Journal of Biological Chemistry. Feb, 2016  |   Pubmed ID: 26683377
• Correlative Analysis of MiRNA Expression and Oncotype Dx Recurrence Score in Estrogen Receptor Positive Breast Carcinomas
  PloS One. 2015  |   Pubmed ID: 26717565
• A Novel Aspirin Prodrug Inhibits NFκB Activity and Breast Cancer Stem Cell Properties
  BMC Cancer. Nov, 2015  |   Pubmed ID: 26530254
• NFκB Affects Estrogen Receptor Expression and Activity in Breast Cancer Through Multiple Mechanisms
  Molecular and Cellular Endocrinology. Dec, 2015  |   Pubmed ID: 25450861
• Growth Hormone Potentiates 17β-estradiol-dependent Breast Cancer Cell Proliferation Independently of IGF-I Receptor Signaling
  Endocrinology. Sep, 2013  |   Pubmed ID: 23782942
• 14-3-3ζ As a Predictor of Early Time to Recurrence and Distant Metastasis in Hormone Receptor-positive and -negative Breast Cancers
  Breast Cancer Research and Treatment. Feb, 2013  |   Pubmed ID: 23271328
• Minireview: Inflammation: an Instigator of More Aggressive Estrogen Receptor (ER) Positive Breast Cancers
  Molecular Endocrinology (Baltimore, Md.). Mar, 2012  |   Pubmed ID: 22301780
• CBP Mediates NF-κB-dependent Histone Acetylation and Estrogen Receptor Recruitment to an Estrogen Response Element in the BIRC3 Promoter
  Molecular and Cellular Biology. Jan, 2012  |   Pubmed ID: 22083956
• An Integrated Bioinformatics Approach Identifies Elevated Cyclin E2 Expression and E2F Activity As Distinct Features of Tamoxifen Resistant Breast Tumors
  PloS One. 2011  |   Pubmed ID: 21789246
• The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells
  Molecular Endocrinology (Baltimore, Md.). May, 2011  |   Pubmed ID: 21372145
• Estrogen Promotes Breast Cancer Cell Survival in an Inhibitor of Apoptosis (IAP)-dependent Manner
  Hormones & Cancer. Jun, 2010  |   Pubmed ID: 21152357
• Proinflammatory Cytokines Enhance Estrogen-dependent Expression of the Multidrug Transporter Gene ABCG2 Through Estrogen Receptor and NF{kappa}B Cooperativity at Adjacent Response Elements
  The Journal of Biological Chemistry. Oct, 2010  |   Pubmed ID: 20705611
• Estrogenic and Progestagenic Effects of Extracts of Justicia Pectoralis Jacq., an Herbal Medicine from Costa Rica Used for the Treatment of Menopause and PMS
  Maturitas. Jul, 2010  |   Pubmed ID: 20452152
• Positive Cross-talk Between Estrogen Receptor and NF-kappaB in Breast Cancer
  Cancer Research. Dec, 2009  |   Pubmed ID: 19920189
• Estrogenic Effects of Herbal Medicines from Costa Rica Used for the Management of Menopausal Symptoms
  Menopause (New York, N.Y.). Jul-Aug, 2009  |   Pubmed ID: 19424091
• Synergistic Up-regulation of Prostaglandin E Synthase Expression in Breast Cancer Cells by 17beta-estradiol and Proinflammatory Cytokines
  Endocrinology. Dec, 2008  |   Pubmed ID: 18703630
• Structure-activity Relationships for a Family of Benzothiophene Selective Estrogen Receptor Modulators Including Raloxifene and Arzoxifene
  ChemMedChem. Oct, 2007  |   Pubmed ID: 17654759
• Estrogen-regulated Gene Networks in Human Breast Cancer Cells: Involvement of E2F1 in the Regulation of Cell Proliferation
  Molecular Endocrinology (Baltimore, Md.). Sep, 2007  |   Pubmed ID: 17550982
• Gene Expression Preferentially Regulated by Tamoxifen in Breast Cancer Cells and Correlations with Clinical Outcome
  Cancer Research. Jul, 2006  |   Pubmed ID: 16849584
• Impact of Estrogen Receptor Beta on Gene Networks Regulated by Estrogen Receptor Alpha in Breast Cancer Cells
  Endocrinology. Oct, 2006  |   Pubmed ID: 16809442
• Estrogen Down-regulation of the Corepressor N-CoR: Mechanism and Implications for Estrogen Derepression of N-CoR-regulated Genes
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005  |   Pubmed ID: 16141343
• Distinctive Actions of Membrane-targeted Versus Nuclear Localized Estrogen Receptors in Breast Cancer Cells
  Molecular Endocrinology (Baltimore, Md.). Jun, 2005  |   Pubmed ID: 15831524
• Therapeutic Targeting in the Estrogen Receptor Hormonal Pathway
  Seminars in Oncology. Feb, 2004  |   Pubmed ID: 15052541
• Transcriptional Profiling of Estrogen-regulated Gene Expression Via Estrogen Receptor (ER) Alpha or ERbeta in Human Osteosarcoma Cells: Distinct and Common Target Genes for These Receptors
  Endocrinology. Jul, 2004  |   Pubmed ID: 15033914
• Selective Estrogen Receptor Modulators: Discrimination of Agonistic Versus Antagonistic Activities by Gene Expression Profiling in Breast Cancer Cells
  Cancer Research. Feb, 2004  |   Pubmed ID: 14973112
• Profiling of Estrogen Up- and Down-regulated Gene Expression in Human Breast Cancer Cells: Insights into Gene Networks and Pathways Underlying Estrogenic Control of Proliferation and Cell Phenotype
  Endocrinology. Oct, 2003  |   Pubmed ID: 12959972
• Response-specific and Ligand Dose-dependent Modulation of Estrogen Receptor (ER) Alpha Activity by ERbeta in the Uterus
  Endocrinology. Jul, 2003  |   Pubmed ID: 12810572
• Prolactin Regulation of Estrogen Receptor Expression
  Trends in Endocrinology and Metabolism: TEM. Apr, 2003  |   Pubmed ID: 12670737
• Regulation of Nuclear Receptor Transcriptional Activity by a Novel DEAD Box RNA Helicase (DP97)
  The Journal of Biological Chemistry. Feb, 2003  |   Pubmed ID: 12466272