Joshua D. Nosanchuk Department of Microbiology and Immunology Albert Einstein College of Medicine Biography Publications Institution JoVE Articles Joshua D. Nosanchuk has not added a biography. If you are Joshua D. Nosanchuk and would like to personalize this page please email our Author Liaison for assistance. Publications Nitric Oxide-Releasing Nanoparticles Accelerate Wound Healing by Promoting Fibroblast Migration and Collagen Deposition The American Journal of Pathology. Feb, 2012 | Pubmed ID: 22306734 The Identification of Gene Duplication and the Role of Secreted Aspartyl Proteinase 1 in Candida Parapsilosis Virulence The Journal of Infectious Diseases. Feb, 2012 | Pubmed ID: 22301631 Radioimmunotherapy of Fungal Diseases: the Therapeutic Potential of Cytocidal Radiation Delivered by Antibody Targeting Fungal Cell Surface Antigens Frontiers in Microbiology. 2011 | Pubmed ID: 22275913 Surface Architecture of Histoplasma Capsulatum Frontiers in Microbiology. 2011 | Pubmed ID: 22121356 Effects of Microplusin, a Copper-chelating Antimicrobial Peptide, Against Cryptococcus Neoformans FEMS Microbiology Letters. Nov, 2011 | Pubmed ID: 22092765 Vesicular Transport Systems in Fungi Future Microbiology. Nov, 2011 | Pubmed ID: 22082294 Secreted Lipases Supply Fatty Acids for Yeast Growth in the Absence of De Novo Fatty Acid Synthesis Virulence. Nov-Dec, 2011 | Pubmed ID: 22030857 Improved Antimicrobial Efficacy with Nitric Oxide Releasing Nanoparticle Generated S-nitrosoglutathione Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2011 | Pubmed ID: 21946032 Sodium Butyrate Inhibits Pathogenic Yeast Growth and Enhances the Functions of Macrophages The Journal of Antimicrobial Chemotherapy. Nov, 2011 | Pubmed ID: 21911344 Lipid Droplet Formation Protects Against Gluco/lipotoxicity in Candida Parapsilosis: an Essential Role of Fatty Acid Desaturase Ole1 Cell Cycle (Georgetown, Tex.). Sep, 2011 | Pubmed ID: 21897120 The Homeostasis of Iron, Copper, and Zinc in Paracoccidioides Brasiliensis, Cryptococcus Neoformans Var. Grubii, and Cryptococcus Gattii: a Comparative Analysis Frontiers in Microbiology. 2011 | Pubmed ID: 21833306 Detection of Antibodies Against Paracoccidioides Brasiliensis Melanin in in Vitro and in Vivo Studies During Infection Clinical and Vaccine Immunology : CVI. Oct, 2011 | Pubmed ID: 21813659 A Rat Model of Neonatal Candidiasis Demonstrates the Importance of Lipases As Virulence Factors for Candida Albicans and Candida Parapsilosis Mycopathologia. Sep, 2011 | Pubmed ID: 21667319 Susceptibility of Gram-positive and -negative Bacteria to Novel Nitric Oxide-releasing Nanoparticle Technology Virulence. May-Jun, 2011 | Pubmed ID: 21577055 Melanogenesis in Dermatophyte Species in Vitro and During Infection Microbiology (Reading, England). Aug, 2011 | Pubmed ID: 21565930 Candida Parapsilosis Fat Storage-inducing Transmembrane (FIT) Protein 2 Regulates Lipid Droplet Formation and Impacts Virulence Microbes and Infection / Institut Pasteur. Jul, 2011 | Pubmed ID: 21396481 Mycobacteria Release Active Membrane Vesicles That Modulate Immune Responses in a TLR2-dependent Manner in Mice The Journal of Clinical Investigation. Apr, 2011 | Pubmed ID: 21364279 Autophagy-related Lipase FgATG15 of Fusarium Graminearum is Important for Lipid Turnover and Plant Infection Fungal Genetics and Biology : FG & B. Mar, 2011 | Pubmed ID: 21094265 The Stearoyl-coenzyme A Desaturase 1 is Essential for Virulence and Membrane Stress in Candida Parapsilosis Through Unsaturated Fatty Acid Production Infection and Immunity. Jan, 2011 | Pubmed ID: 20974817 Phenylalanine Hydroxylase (PAH) from the Lower Eukaryote Leishmania Major Molecular and Biochemical Parasitology. Jan, 2011 | Pubmed ID: 20887755 Biogenesis of Extracellular Vesicles in Yeast: Many Questions with Few Answers Communicative & Integrative Biology. Nov, 2010 | Pubmed ID: 21331232 The Use of Nitric Oxide Releasing Nanoparticles As a Treatment Against Acinetobacter Baumannii in Wound Infections Virulence. Mar-Apr, 2010 | Pubmed ID: 21178416 Monoclonal Antibodies Against Peptidorhamnomannans of Scedosporium Apiospermum Enhance the Pathogenicity of the Fungus PLoS Neglected Tropical Diseases. 2010 | Pubmed ID: 20976055 Fungal Cell Gigantism During Mammalian Infection PLoS Pathogens. 2010 | Pubmed ID: 20585557 Characterization of Yeast Extracellular Vesicles: Evidence for the Participation of Different Pathways of Cellular Traffic in Vesicle Biogenesis PloS One. 2010 | Pubmed ID: 20559436 A Histoplasma Capsulatum-specific IgG1 Isotype Monoclonal Antibody, H1C, to a 70-kilodalton Cell Surface Protein is Not Protective in Murine Histoplasmosis Clinical and Vaccine Immunology : CVI. Jul, 2010 | Pubmed ID: 20484567 Melanin-covered Nanoparticles for Protection of Bone Marrow During Radiation Therapy of Cancer International Journal of Radiation Oncology, Biology, Physics. Dec, 2010 | Pubmed ID: 20421152 Demonstration of Antibiofilm and Antifungal Efficacy of Chitosan Against Candidal Biofilms, Using an in Vivo Central Venous Catheter Model The Journal of Infectious Diseases. May, 2010 | Pubmed ID: 20331379 Aggregation of Streptococcus Pneumoniae by a Pneumococcal Capsular Polysaccharide-specific Human Monoclonal IgM Correlates with Antibody Efficacy in Vivo Clinical and Vaccine Immunology : CVI. May, 2010 | Pubmed ID: 20200186 Extracellular Vesicles from Cryptococcus Neoformans Modulate Macrophage Functions Infection and Immunity. Apr, 2010 | Pubmed ID: 20145096 Cryptococcus Neoformans Responds to Mannitol by Increasing Capsule Size in Vitro and in Vivo Cellular Microbiology. Jun, 2010 | Pubmed ID: 20070311 The Use of Chitosan to Damage Cryptococcus Neoformans Biofilms Biomaterials. Feb, 2010 | Pubmed ID: 19819009 Fatty Acid Synthase Impacts the Pathobiology of Candida Parapsilosis in Vitro and During Mammalian Infection PloS One. 2009 | Pubmed ID: 20027295 Nitric Oxide Releasing Nanoparticles Are Therapeutic for Staphylococcus Aureus Abscesses in a Murine Model of Infection PloS One. 2009 | Pubmed ID: 19915659 Acetylsalicylic Acid (aspirin) Reduces Damage to Reconstituted Human Tissues Infected with Candida Species by Inhibiting Extracellular Fungal Lipases Microbes and Infection / Institut Pasteur. Dec, 2009 | Pubmed ID: 19703582 Methamphetamine Enhances Histoplasmosis by Immunosuppression of the Host The Journal of Infectious Diseases. Jul, 2009 | Pubmed ID: 19473099 Antimicrobial and Healing Efficacy of Sustained Release Nitric Oxide Nanoparticles Against Staphylococcus Aureus Skin Infection The Journal of Investigative Dermatology. Oct, 2009 | Pubmed ID: 19387479 Growth Conditions Influence Melanization of Brazilian Clinical Sporothrix Schenckii Isolates Microbes and Infection / Institut Pasteur. Apr, 2009 | Pubmed ID: 19328867 Vesicular Transport Across the Fungal Cell Wall Trends in Microbiology. Apr, 2009 | Pubmed ID: 19299133 Radioimmunotherapy of Experimental Human Metastatic Melanoma with Melanin-binding Antibodies and in Combination with Dacarbazine Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19293257 Iatrogenic Meningitis in an Obstetric Patient After Combined Spinal-epidural Analgesia: Case Report and Review of the Literature Southern Medical Journal. Mar, 2009 | Pubmed ID: 19204609 Monoclonal Antibodies to Heat Shock Protein 60 Alter the Pathogenesis of Histoplasma Capsulatum Infection and Immunity. Apr, 2009 | Pubmed ID: 19179416 Vesicular Trans-Cell Wall Transport in Fungi: A Mechanism for the Delivery of Virulence-Associated Macromolecules? Lipid Insights. Aug, 2008 | Pubmed ID: 20617119 A Role for Vesicular Transport of Macromolecules Across Cell Walls in Fungal Pathogenesis Communicative & Integrative Biology. 2008 | Pubmed ID: 19169363 Candida Parapsilosis, an Emerging Fungal Pathogen Clinical Microbiology Reviews. Oct, 2008 | Pubmed ID: 18854483 Melanin As a Virulence Factor of Paracoccidioides Brasiliensis and Other Dimorphic Pathogenic Fungi: a Minireview Mycopathologia. Apr-May, 2008 | Pubmed ID: 18777637 Histoplasma Capsulatum at the Host-pathogen Interface Microbes and Infection / Institut Pasteur. Jul, 2008 | Pubmed ID: 18672088 A Monoclonal Antibody to Histoplasma Capsulatum Alters the Intracellular Fate of the Fungus in Murine Macrophages Eukaryotic Cell. Jul, 2008 | Pubmed ID: 18487350 The Radioprotective Properties of Fungal Melanin Are a Function of Its Chemical Composition, Stable Radical Presence and Spatial Arrangement Pigment Cell & Melanoma Research. Apr, 2008 | Pubmed ID: 18426412 Vesicular Transport in Histoplasma Capsulatum: an Effective Mechanism for Trans-cell Wall Transfer of Proteins and Lipids in Ascomycetes Cellular Microbiology. Aug, 2008 | Pubmed ID: 18419773 Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis PLoS Pathogens. Feb, 2008 | Pubmed ID: 18282092 The PD-1/PD-L Costimulatory Pathway Critically Affects Host Resistance to the Pathogenic Fungus Histoplasma Capsulatum Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18268348 Extracellular Vesicles Produced by Cryptococcus Neoformans Contain Protein Components Associated with Virulence Eukaryotic Cell. Jan, 2008 | Pubmed ID: 18039940 Voriconazole Inhibits Melanization in Cryptococcus Neoformans Antimicrobial Agents and Chemotherapy. Dec, 2007 | Pubmed ID: 17923488 Phage Display Library Derived Peptides That Bind to Human Tumor Melanin As Potential Vehicles for Targeted Radionuclide Therapy of Metastatic Melanoma Bioconjugate Chemistry. Nov-Dec, 2007 | Pubmed ID: 17907769 Caspofungin Reduces the Incidence of Fungal Contamination in Cell Culture Mycopathologia. Dec, 2007 | Pubmed ID: 17899440 Targeted Gene Deletion in Candida Parapsilosis Demonstrates the Role of Secreted Lipase in Virulence The Journal of Clinical Investigation. Oct, 2007 | Pubmed ID: 17853941 Monoclonal Antibody to Fungal Glucosylceramide Protects Mice Against Lethal Cryptococcus Neoformans Infection Clinical and Vaccine Immunology : CVI. Oct, 2007 | Pubmed ID: 17715331 Lipase 8 Affects the Pathogenesis of Candida Albicans Infection and Immunity. Oct, 2007 | Pubmed ID: 17646357 Immunoglobulins G, M, and A Against Sporothrix Schenckii Exoantigens in Patients with Sporotrichosis Before and During Treatment with Itraconazole Clinical and Vaccine Immunology : CVI. Sep, 2007 | Pubmed ID: 17634504 Ionizing Radiation Changes the Electronic Properties of Melanin and Enhances the Growth of Melanized Fungi PloS One. 2007 | Pubmed ID: 17520016 Virulence of Candida Parapsilosis, Candida Orthopsilosis, and Candida Metapsilosis in Reconstituted Human Tissue Models Fungal Genetics and Biology : FG & B. Dec, 2007 | Pubmed ID: 17391997 Use of Mycelial-phase Sporothrix Schenckii Exoantigens in an Enzyme-linked Immunosorbent Assay for Diagnosis of Sporotrichosis by Antibody Detection Clinical and Vaccine Immunology : CVI. Mar, 2007 | Pubmed ID: 17215334 Coccidioides Posadasii Produces Melanin in Vitro and During Infection Fungal Genetics and Biology : FG & B. Jun, 2007 | Pubmed ID: 17074521 Synthetic Consolidants Attacked by Melanin-producing Fungi: Case Study of the Biodeterioration of Milan (Italy) Cathedral Marble Treated with Acrylics Applied and Environmental Microbiology. Jan, 2007 | Pubmed ID: 17071788 DIAGNOSIS OF HISTOPLASMOSIS Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]. Jan, 2006 | Pubmed ID: 20445761 Current Status and Future of Antifungal Therapy for Systemic Mycoses Recent Patents on Anti-infective Drug Discovery. Jan, 2006 | Pubmed ID: 18221136 Impact of Melanin on Microbial Virulence and Clinical Resistance to Antimicrobial Compounds Antimicrobial Agents and Chemotherapy. Nov, 2006 | Pubmed ID: 17065617 Efficacy of Voriconazole in Experimental Cryptococcus Neoformans Infection Mycopathologia. Aug, 2006 | Pubmed ID: 16897589 Effects of Disrupting the Polyketide Synthase Gene WdPKS1 in Wangiella [Exophiala] Dermatitidis on Melanin Production and Resistance to Killing by Antifungal Compounds, Enzymatic Degradation, and Extremes in Temperature BMC Microbiology. 2006 | Pubmed ID: 16784529 Radiolabeled Melanin-binding Peptides Are Safe and Effective in Treatment of Human Pigmented Melanoma in a Mouse Model of Disease Cancer Biotherapy & Radiopharmaceuticals. Apr, 2006 | Pubmed ID: 16706632 Adrenal Infections International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Sep, 2006 | Pubmed ID: 16483815 Comparative Analysis of Cryptococcus Neoformans Acid-resistant Particles Generated from Pigmented Cells Grown in Different Laccase Substrates Fungal Genetics and Biology : FG & B. Dec, 2005 | Pubmed ID: 16289955 Effect of Amphotericin B on Capsule and Cell Size in Cryptococcus Neoformans During Murine Infection Antimicrobial Agents and Chemotherapy. Oct, 2005 | Pubmed ID: 16189121 Dual Infections with Pigmented and Albino Strains of Cryptococcus Neoformans in Patients with or Without Human Immunodeficiency Virus Infection in India Journal of Clinical Microbiology. Sep, 2005 | Pubmed ID: 16145139 Synthesis of Melanin Pigment by Candida Albicans in Vitro and During Infection Infection and Immunity. Sep, 2005 | Pubmed ID: 16113337 Melanization of Cryptococcus Neoformans Affects Lung Inflammatory Responses During Cryptococcal Infection Infection and Immunity. Apr, 2005 | Pubmed ID: 15784542 Microstructure of Cell Wall-associated Melanin in the Human Pathogenic Fungus Cryptococcus Neoformans Biochemistry. Mar, 2005 | Pubmed ID: 15751945 Investigation of Fungal Deterioration of Synthetic Paint Binders Using Vibrational Spectroscopic Techniques Macromolecular Bioscience. Jan, 2005 | Pubmed ID: 15635715 Dead Cells in Melanoma Tumors Provide Abundant Antigen for Targeted Delivery of Ionizing Radiation by a MAb to Melanin Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15469923 Blastomyces Dermatitidis Produces Melanin in Vitro and During Infection FEMS Microbiology Letters. Oct, 2004 | Pubmed ID: 15451118 Interaction of Blastomyces Dermatitidis, Sporothrix Schenckii, and Histoplasma Capsulatum with Acanthamoeba Castellanii Infection and Immunity. Jun, 2004 | Pubmed ID: 15155655 Effects of Voriconazole on Cryptococcus Neoformans Antimicrobial Agents and Chemotherapy. Jun, 2004 | Pubmed ID: 15155193 Tuberculosis in New York City: Recent Lessons and a Look Ahead The Lancet Infectious Diseases. May, 2004 | Pubmed ID: 15120345 Susceptibility of the Human Pathogenic Fungi Cryptococcus Neoformans and Histoplasma Capsulatum to Gamma-radiation Versus Radioimmunotherapy with Alpha- and Beta-emitting Radioisotopes Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2004 | Pubmed ID: 14960655 Antibodies to a Cell Surface Histone-like Protein Protect Against Histoplasma Capsulatum The Journal of Clinical Investigation. Oct, 2003 | Pubmed ID: 14561701 'Ready Made' Virulence and 'dual Use' Virulence Factors in Pathogenic Environmental Fungi--the Cryptococcus Neoformans Paradigm Current Opinion in Microbiology. Aug, 2003 | Pubmed ID: 12941400 Cryptococcus Neoformans Virulence is Enhanced After Growth in the Genetically Malleable Host Dictyostelium Discoideum Infection and Immunity. Sep, 2003 | Pubmed ID: 12933827 Experimental Murine Cryptococcal Infection Results in Contamination of Bedding with Cryptococcus Neoformans Contemporary Topics in Laboratory Animal Science / American Association for Laboratory Animal Science. Jul, 2003 | Pubmed ID: 12906395 Budding of Melanized Cryptococcus Neoformans in the Presence or Absence of L-dopa Microbiology (Reading, England). Jul, 2003 | Pubmed ID: 12855745 Synthesis of Melanin-like Pigments by Sporothrix Schenckii in Vitro and During Mammalian Infection Infection and Immunity. Jul, 2003 | Pubmed ID: 12819091 Melanin and Fungi Current Opinion in Infectious Diseases. Apr, 2003 | Pubmed ID: 12734441 The Contribution of Melanin to Microbial Pathogenesis Cellular Microbiology. Apr, 2003 | Pubmed ID: 12675679 Melanization of Cryptococcus Neoformans and Histoplasma Capsulatum Reduces Their Susceptibilities to Amphotericin B and Caspofungin Antimicrobial Agents and Chemotherapy. Nov, 2002 | Pubmed ID: 12384341 Histoplasma Capsulatum Synthesizes Melanin-like Pigments in Vitro and During Mammalian Infection Infection and Immunity. Sep, 2002 | Pubmed ID: 12183562 Administração passiva de anticorpos monoclonais contra H. capsulatum E outros patógenos fúngicos Allan J. Guimarães1, Luis R. Martinez1, Joshua D. Nosanchuk1 1Department of Microbiology and Immunology, Albert Einstein College of Medicine JoVE 2532 Immunology and Infection
Administração passiva de anticorpos monoclonais contra H. capsulatum E outros patógenos fúngicos Allan J. Guimarães1, Luis R. Martinez1, Joshua D. Nosanchuk1 1Department of Microbiology and Immunology, Albert Einstein College of Medicine JoVE 2532 Immunology and Infection