Judith Klumperman

Publications

• Small Molecules to Regulate the GH/IGF1 Axis by Inhibiting the Growth Hormone Receptor Synthesis
  Frontiers in Endocrinology. 2022  |   Pubmed ID: 35966052
• Bimodal Endocytic Probe for Three-dimensional Correlative Light and Electron Microscopy
  Cell Reports Methods. May, 2022  |   Pubmed ID: 35637912
• Correlative Organelle Microscopy: Fluorescence Guided Volume Electron Microscopy of Intracellular Processes
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 35478966
• An Optimized Protocol for Immuno-electron Microscopy of Endogenous LC3
  Autophagy. Apr, 2022  |   Pubmed ID: 35387562
• FER Regulates Endosomal Recycling and is a Predictor for Adjuvant Taxane Benefit in Breast Cancer
  Cell Reports. Apr, 2022  |   Pubmed ID: 35385742
• High Resolution Proteomic Analysis of Subcellular Fractionated Boar Spermatozoa Provides Comprehensive Insights Into Perinuclear Theca-Residing Proteins
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 35252197
• Quantitative Correlative Microscopy Reveals the Ultrastructural Distribution of Endogenous Endosomal Proteins
  The Journal of Cell Biology. Jan, 2022  |   Pubmed ID: 34817533
• The Potential and Limitations of Intrahepatic Cholangiocyte Organoids to Study Inborn Errors of Metabolism
  Journal of Inherited Metabolic Disease. Mar, 2022  |   Pubmed ID: 34671987
• Author Correction: Vps3 and Vps8 Control Integrin Trafficking from Early to Recycling Endosomes and Regulate Integrin-dependent Functions
  Nature Communications. Sep, 2021  |   Pubmed ID: 34588435
• ER - lysosome Contacts at a Pre-axonal Region Regulate Axonal Lysosome Availability
  Nature Communications. Jul, 2021  |   Pubmed ID: 34301956
• α-Synuclein Fibrils Subvert Lysosome Structure and Function for the Propagation of Protein Misfolding Between Cells Through Tunneling Nanotubes
  PLoS Biology. Jul, 2021  |   Pubmed ID: 34283825
• Understanding Membrane Traffic from Molecular Ensemble, Energetics, and the Cell Biology of Participant Components
  Current Opinion in Cell Biology. Aug, 2021  |   Pubmed ID: 34219001
• Cysteamine-bicalutamide Combination Therapy Corrects Proximal Tubule Phenotype in Cystinosis
  EMBO Molecular Medicine. Jul, 2021  |   Pubmed ID: 34165243
• Neurodegenerative VPS41 Variants Inhibit HOPS Function and MTORC1-dependent TFEB/TFE3 Regulation
  EMBO Molecular Medicine. May, 2021  |   Pubmed ID: 33851776
• Pancreatic β-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion
  Diabetes. Feb, 2021  |   Pubmed ID: 33168621
• Apolipoprotein L1-Specific Antibodies Detect Endogenous APOL1 Inside the Endoplasmic Reticulum and on the Plasma Membrane of Podocytes
  Journal of the American Society of Nephrology : JASN. 09, 2020  |   Pubmed ID: 32764142
• Wiskott-Aldrich Syndrome Protein Restricts CGAS/STING Activation by DsDNA Immune Complexes
  JCI Insight. Sep, 2020  |   Pubmed ID: 32721945
• Quantifying Lymphocyte Vacuolization Serves As a Measure of CLN3 Disease Severity
  JIMD Reports. Jul, 2020  |   Pubmed ID: 32685355
• A Paralog-specific Role of COPI Vesicles in the Neuronal Differentiation of Mouse Pluripotent Cells
  Life Science Alliance. Sep, 2020  |   Pubmed ID: 32665377
• Integrated Super Resolution Fluorescence Microscopy and Transmission Electron Microscopy
  Ultramicroscopy. Aug, 2020  |   Pubmed ID: 32470633
• Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening
  SLAS Discovery : Advancing Life Sciences R & D. Jul, 2020  |   Pubmed ID: 32400262
• Single-cell Analysis Uncovers That Metabolic Reprogramming by ErbB2 Signaling is Essential for Cardiomyocyte Proliferation in the Regenerating Heart
  ELife. Dec, 2019  |   Pubmed ID: 31868166
• The Ubiquitin-conjugating Enzyme UBE2QL1 Coordinates Lysophagy in Response to Endolysosomal Damage
  EMBO Reports. Oct, 2019  |   Pubmed ID: 31432621
• DGAT2 Partially Compensates for Lipid-induced ER Stress in Human DGAT1-deficient Intestinal Stem Cells
  Journal of Lipid Research. Oct, 2019  |   Pubmed ID: 31315900
• The Hepatic WASH Complex is Required for Efficient Plasma LDL and HDL Cholesterol Clearance
  JCI Insight. Jun, 2019  |   Pubmed ID: 31167970
• CORVET, CHEVI and HOPS - Multisubunit Tethers of the Endo-lysosomal System in Health and Disease
  Journal of Cell Science. May, 2019  |   Pubmed ID: 31092635
• Visualizing the Cellular Route of Entry of a Cystine-knot Peptide with Xfect Transfection Reagent by Electron Microscopy
  Scientific Reports. May, 2019  |   Pubmed ID: 31061420
• High Accuracy, Fiducial Marker-based Image Registration of Correlative Microscopy Images
  Scientific Reports. Mar, 2019  |   Pubmed ID: 30824844
• The 2018 Correlative Microscopy Techniques Roadmap
  Journal of Physics D: Applied Physics. Nov, 2018  |   Pubmed ID: 30799880
• Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
  Neuron. Dec, 2018  |   Pubmed ID: 30392797
• Fluorescently Labelled Silica Coated Gold Nanoparticles As Fiducial Markers for Correlative Light and Electron Microscopy
  Scientific Reports. Sep, 2018  |   Pubmed ID: 30206379
• Vps3 and Vps8 Control Integrin Trafficking from Early to Recycling Endosomes and Regulate Integrin-dependent Functions
  Nature Communications. Feb, 2018  |   Pubmed ID: 29476049
• Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration
  Theranostics. 2018  |   Pubmed ID: 29463990
• Single Organelle Dynamics Linked to 3D Structure by Correlative Live-cell Imaging and 3D Electron Microscopy
  Traffic (Copenhagen, Denmark). May, 2018  |   Pubmed ID: 29451726
• Ultrastructural Characterization of Membrane Rearrangements Induced by Porcine Epidemic Diarrhea Virus Infection
  Viruses. Sep, 2017  |   Pubmed ID: 28872588
• Improving Comprehension Efficiency of High Content Screening Data Through Interactive Visualizations
  Assay and Drug Development Technologies. 2017  |   Pubmed ID: 28837357
• EB1 and EB3 Regulate Microtubule Minus End Organization and Golgi Morphology
  The Journal of Cell Biology. Oct, 2017  |   Pubmed ID: 28814570
• Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform
  Assay and Drug Development Technologies. Oct, 2016  |   Pubmed ID: 27732064
• Molecular Pathway of Microtubule Organization at the Golgi Apparatus
  Developmental Cell. Oct, 2016  |   Pubmed ID: 27666745
• HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets
  Assay and Drug Development Technologies. Oct, 2016  |   Pubmed ID: 27636821
• Architecture of the Mammalian Golgi
  Cold Spring Harbor Perspectives in Biology. Jul, 2011  |   Pubmed ID: 21502307
• A Flippase-independent Function of ATP8B1, the Protein Affected in Familial Intrahepatic Cholestasis Type 1, is Required for Apical Protein Expression and Microvillus Formation in Polarized Epithelial Cells
  Hepatology (Baltimore, Md.). Jun, 2010  |   Pubmed ID: 20512993
• Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes
  PLoS Biology. Jan, 2010  |   Pubmed ID: 20098723
• Efficient IgM Assembly and Secretion Require the Plasma Cell Induced Endoplasmic Reticulum Protein PERp1
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009  |   Pubmed ID: 19805154
• Glycolipid-dependent Sorting of Melanosomal from Lysosomal Membrane Proteins by Lumenal Determinants
  Traffic (Copenhagen, Denmark). Jun, 2008  |   Pubmed ID: 18373728
• Pre- and Post-Golgi Translocation of Glucosylceramide in Glycosphingolipid Synthesis
  The Journal of Cell Biology. Oct, 2007  |   Pubmed ID: 17923531
• Involvement of a Golgi-resident GPI-anchored Protein in Maintenance of the Golgi Structure
  Molecular Biology of the Cell. Apr, 2007  |   Pubmed ID: 17251550
• Short-chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17101973
• Aberrant Receptor-mediated Endocytosis of Schistosoma Mansoni Glycoproteins on Host Lipoproteins
  PLoS Medicine. Aug, 2006  |   Pubmed ID: 16942390
• Presenilin-1 Exists in Both Pre- and Post-Golgi Compartments and Recycles Via COPI-coated Membranes
  Traffic (Copenhagen, Denmark). Aug, 2003  |   Pubmed ID: 12839498
• A Phosphorylation Site Regulates Sorting of the Vesicular Acetylcholine Transporter to Dense Core Vesicles
  The Journal of Cell Biology. Apr, 2000  |   Pubmed ID: 10769030
• Synaptic Vesicles Form by Budding from Tubular Extensions of Sorting Endosomes in PC12 Cells
  Molecular Biology of the Cell. Dec, 1999  |   Pubmed ID: 10588650
• Dynamic Kinetochore Size Regulation Promotes Microtubule Capture and Chromosome Biorientation in Mitosis
  Nature Cell Biology.   |   Pubmed ID: 29915359