Karen M. Vasquez Division of Pharmacology and Toxicology, College of Pharmacy The University of Texas at Austin Biography Publications Institution JoVE Articles Karen M. Vasquez has not added a biography. If you are Karen M. Vasquez and would like to personalize this page please email our Author Liaison for assistance. Publications Detection of Cis- and Trans-acting Factors in DNA Structure-Induced Genetic Instability Using In Silico and Cellular Approaches Frontiers in Genetics. 2016 | Pubmed ID: 27532010 Translocation and Deletion Breakpoints in Cancer Genomes Are Associated with Potential Non-B DNA-forming Sequences Nucleic Acids Research. Jul, 2016 | Pubmed ID: 27084947 HMGB1 Interacts with XPA to Facilitate the Processing of DNA Interstrand Crosslinks in Human Cells Nucleic Acids Research. Feb, 2016 | Pubmed ID: 26578599 New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity PLoS Genetics. Dec, 2015 | Pubmed ID: 26700634 Long Non-coding RNA: A New Paradigm for Lung Cancer Molecular Carcinogenesis. Nov, 2015 | Pubmed ID: 26332907 Erratum To: The Somatic Autosomal Mutation Matrix in Cancer Genomes Human Genetics. Aug, 2015 | Pubmed ID: 26071096 The Somatic Autosomal Mutation Matrix in Cancer Genomes Human Genetics. Aug, 2015 | Pubmed ID: 26001532 Local DNA Dynamics Shape Mutational Patterns of Mononucleotide Repeats in Human Genomes Nucleic Acids Research. May, 2015 | Pubmed ID: 25897114 Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes Cell Reports. Mar, 2015 | Pubmed ID: 25772355 Impact of Alternative DNA Structures on DNA Damage, DNA Repair, and Genetic Instability DNA Repair. Jul, 2014 | Pubmed ID: 24767258 Mechanisms of Base Substitution Mutagenesis in Cancer Genomes Genes. Mar, 2014 | Pubmed ID: 24705290 Triplex-forming Oligonucleotides Targeting C-MYC Potentiate the Anti-tumor Activity of Gemcitabine in a Mouse Model of Human Cancer Molecular Carcinogenesis. Sep, 2014 | Pubmed ID: 23681918 Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease PLoS Genetics. 2013 | Pubmed ID: 24086153 DHX9 Helicase is Involved in Preventing Genomic Instability Induced by Alternatively Structured DNA in Human Cells Nucleic Acids Research. Dec, 2013 | Pubmed ID: 24049074 Methods to Detect Replication-dependent and Replication-independent DNA Structure-induced Genetic Instability Methods (San Diego, Calif.). Nov, 2013 | Pubmed ID: 23954565 DNA Structure Matters Genome Medicine. 2013 | Pubmed ID: 23796271 FANCM and FAAP24 Maintain Genome Stability Via Cooperative As Well As Unique Functions Molecular Cell. Mar, 2013 | Pubmed ID: 23333308 The Yin and Yang of Repair Mechanisms in DNA Structure-induced Genetic Instability Mutation Research. Mar-Apr, 2013 | Pubmed ID: 23219604 Direct and Inverted Repeats Elicit Genetic Instability by Both Exploiting and Eluding DNA Double-strand Break Repair Systems in Mycobacteria PloS One. 2012 | Pubmed ID: 23251422 2,6-Dithiopurine, a Nucleophilic Scavenger, Protects Against Mutagenesis in Mouse Skin Treated in Vivo with 2-(chloroethyl) Ethyl Sulfide, a Mustard Gas Analog Toxicology and Applied Pharmacology. Sep, 2012 | Pubmed ID: 22732900 On the Sequence-directed Nature of Human Gene Mutation: the Role of Genomic Architecture and the Local DNA Sequence Environment in Mediating Gene Mutations Underlying Human Inherited Disease Human Mutation. Oct, 2011 | Pubmed ID: 21853507 Triplex Technology in Studies of DNA Damage, DNA Repair, and Mutagenesis Biochimie. Aug, 2011 | Pubmed ID: 21501652 Non-B DNA-forming Sequences and WRN Deficiency Independently Increase the Frequency of Base Substitution in Human Cells The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21285356 Human DHX9 Helicase Unwinds Triple-helical DNA Structures Biochemistry. Aug, 2010 | Pubmed ID: 20669935 DNA Interstrand Crosslinks: Repair, Cell Signaling, and Therapeutic Implications Environmental and Molecular Mutagenesis. Jul, 2010 | Pubmed ID: 20577999 Pathways for Double-strand Break Repair in Genetically Unstable Z-DNA-forming Sequences Journal of Molecular Biology. May, 2010 | Pubmed ID: 20347845 Targeting and Processing of Site-specific DNA Interstrand Crosslinks Environmental and Molecular Mutagenesis. Jul, 2010 | Pubmed ID: 20196133 2,6-Dithiopurine Blocks Toxicity and Mutagenesis in Human Skin Cells Exposed to Sulfur Mustard Analogues, 2-chloroethyl Ethyl Sulfide and 2-chloroethyl Methyl Sulfide Chemical Research in Toxicology. Mar, 2010 | Pubmed ID: 20050631 Non-B DNA Structure-induced Genetic Instability and Evolution Cellular and Molecular Life Sciences : CMLS. Jan, 2010 | Pubmed ID: 19727556 Targeted Gene Conversion Induced by Triplex-directed Psoralen Interstrand Crosslinks in Mammalian Cells Nucleic Acids Research. Oct, 2009 | Pubmed ID: 19726585 Cruciform-forming Inverted Repeats Appear to Have Mediated Many of the Microinversions That Distinguish the Human and Chimpanzee Genomes Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 2009 | Pubmed ID: 19475482 Mismatch Repair and Nucleotide Excision Repair Proteins Cooperate in the Recognition of DNA Interstrand Crosslinks Nucleic Acids Research. Jul, 2009 | Pubmed ID: 19468048 Human HMGB1 Directly Facilitates Interactions Between Nucleotide Excision Repair Proteins on Triplex-directed Psoralen Interstrand Crosslinks DNA Repair. Jul, 2009 | Pubmed ID: 19446504 HMGB1: the Jack-of-all-trades Protein is a Master DNA Repair Mechanic Molecular Carcinogenesis. Jul, 2009 | Pubmed ID: 19360789 Intrinsic Genomic Instability from Naturally Occurring DNA Structures: An Introduction to the Special Issue Molecular Carcinogenesis. Apr, 2009 | Pubmed ID: 19306307 Methods to Determine DNA Structural Alterations and Genetic Instability Methods (San Diego, Calif.). May, 2009 | Pubmed ID: 19245837 Models for Chromosomal Replication-independent Non-B DNA Structure-induced Genetic Instability Molecular Carcinogenesis. Apr, 2009 | Pubmed ID: 19123200 Role of TLS DNA Polymerases Eta and Kappa in Processing Naturally Occurring Structured DNA in Human Cells Molecular Carcinogenesis. Apr, 2009 | Pubmed ID: 19117014 DNA Structure-induced Genomic Instability in Vivo Journal of the National Cancer Institute. Dec, 2008 | Pubmed ID: 19066276 Efficient Processing of TFO-directed Psoralen DNA Interstrand Crosslinks by the UvrABC Nuclease Nucleic Acids Research. Dec, 2008 | Pubmed ID: 18996898 Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling in Response to DNA Interstrand Crosslinks, While MSH2 Functions in DNA Repair PLoS Genetics. Sep, 2008 | Pubmed ID: 18787700 High Mobility Group Protein B1 Enhances DNA Repair and Chromatin Modification After DNA Damage Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18650382 Processing of Triplex-directed Psoralen DNA Interstrand Crosslinks by Recombination Mechanisms Nucleic Acids Research. Aug, 2008 | Pubmed ID: 18628293 Targeted Generation of DNA Strand Breaks Using Pyrene-conjugated Triplex-forming Oligonucleotides Biochemistry. Jun, 2008 | Pubmed ID: 18473480 Inhibitory Effect of a Short Z-DNA Forming Sequence on Transcription Elongation by T7 RNA Polymerase Nucleic Acids Research. Jun, 2008 | Pubmed ID: 18400779 DNA Triple Helices: Biological Consequences and Therapeutic Potential Biochimie. Aug, 2008 | Pubmed ID: 18331847 A Triplex-forming Sequence from the Human C-MYC Promoter Interferes with DNA Transcription The Journal of Biological Chemistry. Nov, 2007 | Pubmed ID: 17785457 Z-DNA, an Active Element in the Genome Frontiers in Bioscience : a Journal and Virtual Library. May, 2007 | Pubmed ID: 17485386 Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model Cancer Research. Apr, 2007 | Pubmed ID: 17440093 High-affinity Triplex-forming Oligonucleotide Target Sequences in Mammalian Genomes Molecular Carcinogenesis. Jan, 2007 | Pubmed ID: 17013831 A Web-based Search Engine for Triplex-forming Oligonucleotide Target Sequences Oligonucleotides. 2006 | Pubmed ID: 16764543 Targeting Oncogenes to Improve Breast Cancer Chemotherapy Cancer Research. Apr, 2006 | Pubmed ID: 16618728 Non-B DNA Structure-induced Genetic Instability Mutation Research. Jun, 2006 | Pubmed ID: 16516932 Z-DNA-forming Sequences Generate Large-scale Deletions in Mammalian Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16473937 Repair of Genome Destabilizing Lesions Radiation Research. Oct, 2005 | Pubmed ID: 16187737 Human XPC-hHR23B Interacts with XPA-RPA in the Recognition of Triplex-directed Psoralen DNA Interstrand Crosslinks Nucleic Acids Research. 2005 | Pubmed ID: 15914671 Mismatch Repair Participates in Error-free Processing of DNA Interstrand Crosslinks in Human Cells EMBO Reports. Jun, 2005 | Pubmed ID: 15891767 Interplay Between Human High Mobility Group Protein 1 and Replication Protein A on Psoralen-cross-linked DNA Biochemistry. Mar, 2005 | Pubmed ID: 15766246 Naturally Occurring H-DNA-forming Sequences Are Mutagenic in Mammalian Cells Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15342911 Mutation Frequencies in Murine Keratinocytes As a Function of Carcinogenic Status Molecular Carcinogenesis. Jun, 2004 | Pubmed ID: 15170817 Critical DNA Damage Recognition Functions of XPC-hHR23B and XPA-RPA in Nucleotide Excision Repair Molecular Carcinogenesis. Sep, 2003 | Pubmed ID: 12949838 Site-directed Recombination Via Bifunctional PNA-DNA Conjugates Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12461167 Triplex-forming Oligonucleotides: Principles and Applications Quarterly Reviews of Biophysics. Feb, 2002 | Pubmed ID: 11997982 Human XPA and RPA DNA Repair Proteins Participate in Specific Recognition of Triplex-induced Helical Distortions Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11972036 Verktøy for å studere rollen til Architectural Protein HMGB1 i behandlingen av Helix forvrenge, Site-spesifikke DNA Interstrand tverrbindinger Anirban Mukherjee1, Karen M. Vasquez1 1Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin Genetics
Verktøy for å studere rollen til Architectural Protein HMGB1 i behandlingen av Helix forvrenge, Site-spesifikke DNA Interstrand tverrbindinger Anirban Mukherjee1, Karen M. Vasquez1 1Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin Genetics