Karla J. Hutt

Publications

• The PARP Inhibitor, Olaparib, Depletes the Ovarian Reserve in Mice: Implications for Fertility Preservation
  Human Reproduction (Oxford, England). Aug, 2020  |   Pubmed ID: 32604417
• Oocytes Can Efficiently Repair DNA Double-strand Breaks to Restore Genetic Integrity and Protect Offspring Health
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2020  |   Pubmed ID: 32381741
• Moderate Episodic Prenatal Alcohol Does Not Impact Female Offspring Fertility in Rats
  Reproduction (Cambridge, England). 05, 2020  |   Pubmed ID: 32168471
• Do Cancer Therapies Damage the Uterus and Compromise Fertility?
  Human Reproduction Update. Feb, 2020  |   Pubmed ID: 31863097
• Evaluation of Mitochondria in Oocytes Following γ-irradiation
  Scientific Reports. 12, 2019  |   Pubmed ID: 31882895
• Do BRCA1 and BRCA2 Gene Mutation Carriers Have a Reduced Ovarian Reserve? Protocol for a Prospective Observational Study
  BMJ Open. 11, 2019  |   Pubmed ID: 31772111
• Nicotinamide Mononucleotide Does Not Protect the Ovarian Reserve from Cancer Treatments
  Reproduction (Cambridge, England). Nov, 2019  |   Pubmed ID: 31751296
• Vincristine Chemotherapy Induces Atresia of Growing Ovarian Follicles in Mice
  Toxicological Sciences : an Official Journal of the Society of Toxicology. 05, 2019  |   Pubmed ID: 30657998
• Oocytes from Stem Cells
  Best Practice & Research. Clinical Obstetrics & Gynaecology. Feb, 2019  |   Pubmed ID: 30120061
• Maternal Low-protein Diet Programmes Low Ovarian Reserve in Offspring
  Reproduction (Cambridge, England). 10, 2018  |   Pubmed ID: 30306601
• Methylation of All BRCA1 Copies Predicts Response to the PARP Inhibitor Rucaparib in Ovarian Carcinoma
  Nature Communications. 09, 2018  |   Pubmed ID: 30266954
• Multidose 5-Fluorouracil is Highly Toxic to Growing Ovarian Follicles in Mice
  Toxicological Sciences : an Official Journal of the Society of Toxicology. 11, 2018  |   Pubmed ID: 30085306
• Maternal Low-protein Diet Programmes Low Ovarian Reserve in Offspring
  Reproduction (Cambridge, England). 10, 2018  |   Pubmed ID: 29991566
• Loss of PUMA Protects the Ovarian Reserve During DNA-damaging Chemotherapy and Preserves Fertility
  Cell Death & Disease. 05, 2018  |   Pubmed ID: 29795269
• The Capacity of Oocytes for DNA Repair
  Cellular and Molecular Life Sciences : CMLS. 08, 2018  |   Pubmed ID: 29748894
• Dacarbazine Depletes the Ovarian Reserve in Mice and Depletion is Enhanced with Age
  Scientific Reports. 04, 2018  |   Pubmed ID: 29695822
• Examination of the Ovotoxicity of 5-fluorouracil in Mice
  Journal of Assisted Reproduction and Genetics. Jun, 2018  |   Pubmed ID: 29589294
• The Importance of DNA Repair for Maintaining Oocyte Quality in Response to Anti-cancer Treatments, Environmental Toxins and Maternal Ageing
  Human Reproduction Update. Mar, 2018  |   Pubmed ID: 29377997
• The Ovarian Reserve is Depleted During Puberty in a Hormonally Driven Process Dependent on the Pro-apoptotic Protein BMF
  Cell Death & Disease. 08, 2017  |   Pubmed ID: 28771225
• BCL2-modifying Factor Promotes Germ Cell Loss During Murine Oogenesis
  Reproduction (Cambridge, England). May, 2016  |   Pubmed ID: 26917450
• How Is the Number of Primordial Follicles in the Ovarian Reserve Established?
  Biology of Reproduction. Nov, 2015  |   Pubmed ID: 26423124
• Ovarian Reserve Screening: a Scientific and Ethical Analysis
  Human Reproduction (Oxford, England). Apr, 2015  |   Pubmed ID: 25637623
• What is the "ovarian Reserve"?
  Fertility and Sterility. Mar, 2015  |   Pubmed ID: 25500021
• Dual Roles for Id4 in the Regulation of Estrogen Signaling in the Mammary Gland and Ovary
  Development (Cambridge, England). Aug, 2014  |   Pubmed ID: 25038044
• Loss of the Proapoptotic BH3-only Protein BCL-2 Modifying Factor Prolongs the Fertile Life Span in Female Mice
  Biology of Reproduction. Apr, 2014  |   Pubmed ID: 24571986
• Molecular Correlates of Platinum Response in Human High-grade Serous Ovarian Cancer Patient-derived Xenografts
  Molecular Oncology. May, 2014  |   Pubmed ID: 24560445
• DNA Damage-induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-mediated Induction of Puma and Noxa
  Molecular Cell. Nov, 2012  |   Pubmed ID: 23000175
• Cisplatin-induced Primordial Follicle Oocyte Killing and Loss of Fertility Are Not Prevented by Imatinib
  Nature Medicine. Aug, 2012  |   Pubmed ID: 22869179