Karolin Luger Biochemistry and Molecular Biology Colorado State University Biography Publications Institution JoVE Articles Karolin Luger has not added a biography. If you are Karolin Luger and would like to personalize this page please email our Author Liaison for assistance. Publications Chaperone Nap1 Shields Histone Surfaces Used in a Nucleosome and Can Put H2A-H2B in an Unconventional Tetrameric Form Molecular Cell. Aug, 2013 | Pubmed ID: 23973327 Histone Chaperone FACT Action During Transcription Through Chromatin by RNA Polymerase II Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23610384 Evidence for Monomeric Actin Function in INO80 Chromatin Remodeling Nature Structural & Molecular Biology. Apr, 2013 | Pubmed ID: 23524535 The Role of the Nucleosome Acidic Patch in Modulating Higher Order Chromatin Structure Journal of the Royal Society, Interface / the Royal Society. May, 2013 | Pubmed ID: 23446052 Linker Histone H1.0 Interacts with an Extensive Network of Proteins Found in the Nucleolus Nucleic Acids Research. Feb, 2013 | Pubmed ID: 23435226 Stability of Nucleosomes Containing Homogenously Ubiquitylated H2A and H2B Prepared Using Semisynthesis Journal of the American Chemical Society. Dec, 2012 | Pubmed ID: 23163596 Structure of Actin-related Protein 8 and Its Contribution to Nucleosome Binding Nucleic Acids Research. Nov, 2012 | Pubmed ID: 22977180 Yeast CAF-1 Assembles Histone (H3-H4)2 Tetramers Prior to DNA Deposition Nucleic Acids Research. Nov, 2012 | Pubmed ID: 22941638 Quantifying Chromatin-associated Interactions: the HI-FI System Methods in Enzymology. 2012 | Pubmed ID: 22910210 Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes The Journal of Biological Chemistry. Sep, 2012 | Pubmed ID: 22854955 New Insights into Nucleosome and Chromatin Structure: an Ordered State or a Disordered Affair? Nature Reviews. Molecular Cell Biology. Jul, 2012 | Pubmed ID: 22722606 Proteins for Packaging, Partitioning, Processing, and Proofing of Nucleic Acids Current Opinion in Structural Biology. Feb, 2012 | Pubmed ID: 22261637 Fluorescence Strategies for High-throughput Quantification of Protein Interactions Nucleic Acids Research. Mar, 2012 | Pubmed ID: 22121211 Understanding Histone Acetyltransferase Rtt109 Structure and Function: How Many Chaperones Does It Take? Current Opinion in Structural Biology. Dec, 2011 | Pubmed ID: 22023828 Histone Chaperone FACT Coordinates Nucleosome Interaction Through Multiple Synergistic Binding Events The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 21969370 Replacement of Histone H3 with CENP-A Directs Global Nucleosome Array Condensation and Loosening of Nucleosome Superhelical Termini Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21949362 Structure and Scm3-mediated Assembly of Budding Yeast Centromeric Nucleosomes Nature Communications. 2011 | Pubmed ID: 21587230 The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21532035 The DEK Oncoprotein is a Su(var) That is Essential to Heterochromatin Integrity Genes & Development. Apr, 2011 | Pubmed ID: 21460035 The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454601 Nucleosome Structure(s) and Stability: Variations on a Theme Annual Review of Biophysics. 2011 | Pubmed ID: 21332355 Biophysical Analysis and Small-angle X-ray Scattering-derived Structures of MeCP2-nucleosome Complexes Nucleic Acids Research. May, 2011 | Pubmed ID: 21278419 A Coupled Equilibrium Approach to Study Nucleosome Thermodynamics Methods in Enzymology. 2011 | Pubmed ID: 21195232 Nucleosome Accessibility Governed by the Dimer/tetramer Interface Nucleic Acids Research. Apr, 2011 | Pubmed ID: 21177647 The Transcription Factor Spn1 Regulates Gene Expression Via a Highly Conserved Novel Structural Motif Journal of Molecular Biology. Nov, 2010 | Pubmed ID: 20875428 Histone Chaperones, Histone Acetylation, and the Fluidity of the Chromogenome Journal of Cellular Physiology. Aug, 2010 | Pubmed ID: 20432449 The Histone Chaperone Nap1 Promotes Nucleosome Assembly by Eliminating Nonnucleosomal Histone DNA Interactions Molecular Cell. Mar, 2010 | Pubmed ID: 20347425 Rise of the Molecular Machines Current Opinion in Structural Biology. Feb, 2010 | Pubmed ID: 20133121 Structural Characterization of H3K56Q Nucleosomes and Nucleosomal Arrays Biochimica Et Biophysica Acta. May-Jun, 2010 | Pubmed ID: 20100606 Methods to Characterize the Effect of DNA-modifying Compounds on Nucleosomal DNA Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 19997884 Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA Journal of Molecular Biology. Feb, 2010 | Pubmed ID: 19962992 A Positive Spin on the Centromere Cell. Jul, 2009 | Pubmed ID: 19596232 Nucleosome-binding Affinity As a Primary Determinant of the Nuclear Mobility of the Pioneer Transcription Factor FoxA Genes & Development. Apr, 2009 | Pubmed ID: 19339686 Histone Chaperone Specificity in Rtt109 Activation Nature Structural & Molecular Biology. Sep, 2008 | Pubmed ID: 19172749 The Effect of H3K79 Dimethylation and H4K20 Trimethylation on Nucleosome and Chromatin Structure Nature Structural & Molecular Biology. Oct, 2008 | Pubmed ID: 18794842 A Thermodynamic Model for Nap1-histone Interactions The Journal of Biological Chemistry. Nov, 2008 | Pubmed ID: 18728017 Histone Chaperones in Nucleosome Eviction and Histone Exchange Current Opinion in Structural Biology. Jun, 2008 | Pubmed ID: 18534842 A Beta-hairpin Comprising the Nuclear Localization Sequence Sustains the Self-associated States of Nucleosome Assembly Protein 1 Journal of Molecular Biology. Jan, 2008 | Pubmed ID: 18068721 Structure of the Drosophila Nucleosome Core Particle Highlights Evolutionary Constraints on the H2A-H2B Histone Dimer Proteins. Apr, 2008 | Pubmed ID: 17957772 A Charged and Contoured Surface on the Nucleosome Regulates Chromatin Compaction Nature Structural & Molecular Biology. Nov, 2007 | Pubmed ID: 17965723 Effects of Photochemically Activated Alkylating Agents of the FR900482 Family on Chromatin Chemistry & Biology. May, 2007 | Pubmed ID: 17524986 Structure and Function of Nucleosome Assembly Proteins Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2006 | Pubmed ID: 16936827 Nucleosome Core Particles Containing a Poly(dA.dT) Sequence Element Exhibit a Locally Distorted DNA Structure Journal of Molecular Biology. Aug, 2006 | Pubmed ID: 16860337 A Feed-forward Repression Mechanism Anchors the Sin3/histone Deacetylase and N-CoR/SMRT Corepressors on Chromatin Molecular and Cellular Biology. Jul, 2006 | Pubmed ID: 16809761 The Histone Variant Macro-H2A Preferentially Forms "hybrid Nucleosomes" The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16803903 Kaposi's Sarcoma-associated Herpesvirus LANA Hitches a Ride on the Chromosome Cell Cycle (Georgetown, Tex.). May, 2006 | Pubmed ID: 16721045 Dynamic Nucleosomes Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 2006 | Pubmed ID: 16506092 The Nucleosomal Surface As a Docking Station for Kaposi's Sarcoma Herpesvirus LANA Science (New York, N.Y.). Feb, 2006 | Pubmed ID: 16469929 The Structure of Nucleosome Assembly Protein 1 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16432217 Structural Characterization of the Histone Variant MacroH2A Molecular and Cellular Biology. Sep, 2005 | Pubmed ID: 16107708 The Core Histone N-terminal Tail Domains Function Independently and Additively During Salt-dependent Oligomerization of Nucleosomal Arrays The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16033758 The Temperature of Flash-cooling Has Dramatic Effects on the Diffraction Quality of Nucleosome Crystals Acta Crystallographica. Section D, Biological Crystallography. Jul, 2005 | Pubmed ID: 15983411 Nucleosome and Chromatin Fiber Dynamics Current Opinion in Structural Biology. Apr, 2005 | Pubmed ID: 15837178 Structure and Dynamic Properties of Nucleosome Core Particles FEBS Letters. Feb, 2005 | Pubmed ID: 15680970 Nucleosomes in Solution Exist As a Mixture of Twist-defect States Journal of Molecular Biology. Jan, 2005 | Pubmed ID: 15567414 Nucleosome Assembly Protein 1 Exchanges Histone H2A-H2B Dimers and Assists Nucleosome Sliding The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15516689 H2A.Z Alters the Nucleosome Surface to Promote HP1alpha-mediated Chromatin Fiber Folding Molecular Cell. Nov, 2004 | Pubmed ID: 15546624 Defined Structural Changes Occur in a Nucleosome Upon Amt1 Transcription Factor Binding Journal of Molecular Biology. Oct, 2004 | Pubmed ID: 15364568 Structural Determinants for Generating Centromeric Chromatin Nature. Jul, 2004 | Pubmed ID: 15282608 Nucleosomes Containing the Histone Variant H2A.Bbd Organize Only 118 Base Pairs of DNA The EMBO Journal. Aug, 2004 | Pubmed ID: 15257289 Molecular Recognition of the Nucleosomal "supergroove" Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15100411 A New Fluorescence Resonance Energy Transfer Approach Demonstrates That the Histone Variant H2AZ Stabilizes the Histone Octamer Within the Nucleosome The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15020582 Reconstitution of Nucleosome Core Particles from Recombinant Histones and DNA Methods in Enzymology. 2004 | Pubmed ID: 14870657 Crystal Structures of Histone Sin Mutant Nucleosomes Reveal Altered Protein-DNA Interactions The EMBO Journal. Jan, 2004 | Pubmed ID: 14739929 Preferential Binding of the Histone (H3-H4)2 Tetramer by NAP1 is Mediated by the Amino-terminal Histone Tails The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12928440 Tax Recruitment of CBP/p300, Via the KIX Domain, Reveals a Potent Requirement for Acetyltransferase Activity That is Chromatin Dependent and Histone Tail Independent Molecular and Cellular Biology. May, 2003 | Pubmed ID: 12724399 Structure and Dynamic Behavior of Nucleosomes Current Opinion in Genetics & Development. Apr, 2003 | Pubmed ID: 12672489 Structure and Dynamics of Nucleosomal DNA Biopolymers. Apr, 2003 | Pubmed ID: 12666179 Histone Chaperones and Nucleosome Assembly Current Opinion in Structural Biology. Feb, 2003 | Pubmed ID: 12581654 Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands Journal of Molecular Biology. Feb, 2003 | Pubmed ID: 12559907 The Tail Does Not Always Wag the Dog Nature Genetics. Oct, 2002 | Pubmed ID: 12244314 Blocking Transcription Through a Nucleosome with Synthetic DNA Ligands Journal of Molecular Biology. Aug, 2002 | Pubmed ID: 12144782 Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 a Resolution Journal of Molecular Biology. Jun, 2002 | Pubmed ID: 12079350 The Essential Histone Variant H2A.Z Regulates the Equilibrium Between Different Chromatin Conformational States Nature Structural Biology. Mar, 2002 | Pubmed ID: 11850638 P300-mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function Molecular and Cellular Biology. Jan, 2002 | Pubmed ID: 11739728 Ассамблея нуклеосомной массивов из рекомбинантных стержневых гистонов и позиционированием нуклеосом ДНК Ryan A. Rogge1, Anna A. Kalashnikova1, Uma M. Muthurajan1, Mary E. Porter-Goff1, Karolin Luger1, Jeffrey C. Hansen1 1Biochemistry and Molecular Biology, Colorado State University JoVE 50354 Biology
Ассамблея нуклеосомной массивов из рекомбинантных стержневых гистонов и позиционированием нуклеосом ДНК Ryan A. Rogge1, Anna A. Kalashnikova1, Uma M. Muthurajan1, Mary E. Porter-Goff1, Karolin Luger1, Jeffrey C. Hansen1 1Biochemistry and Molecular Biology, Colorado State University JoVE 50354 Biology