Kathleen Gabrielson Department of Molecular and Comparative Pathobiology Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Kathleen Gabrielson has not added a biography. If you are Kathleen Gabrielson and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of Cardiovascular Pathology in Animal Models of SARS-CoV-2 Infection: Recommendations Regarding Standardization of Research Methods Comparative Medicine. Feb, 2023 | Pubmed ID: 36731878 Alteration in Tyrosine Phosphorylation of Cardiac Proteome and EGFR Pathway Contribute to Hypertrophic Cardiomyopathy Communications Biology. Nov, 2022 | Pubmed ID: 36380187 HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells Cancer Research. Oct, 2022 | Pubmed ID: 36166646 Canine Idiopathic Arteriopathy, Appendicular Bone Infarcts, and Neoplastic Transformation of Bone Infarcts in 108 Dogs () Comparative Medicine. Oct, 2022 | Pubmed ID: 36113969 Polymeric Nanoparticles for Dual-targeted Theranostic Gene Delivery to Hepatocellular Carcinoma Science Advances. Jul, 2022 | Pubmed ID: 35857843 Intraductal Administration of Transferrin Receptor-targeted Immunotoxin Clears Ductal Carcinoma in Situ in Mouse Models of Breast Cancer-a Preclinical Study Proceedings of the National Academy of Sciences of the United States of America. Jun, 2022 | Pubmed ID: 35675429 The Common Marmoset-Biomedical Research Animal Model Applications and Common Spontaneous Diseases Toxicologic Pathology. Jul, 2022 | Pubmed ID: 35535728 Prenatal Stress Enhances Atherosclerosis and Telomere Shortening in ApoE Knockout Mouse Offspring American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2022 | Pubmed ID: 35411811 Bionized Nanoferrite Particles Alter the Course of Experimental Cryptococcus Neoformans Pneumonia Antimicrobial Agents and Chemotherapy. Apr, 2022 | Pubmed ID: 35293784 Hepatic Steatosis in the Mouse Model of Wilson Disease Coincides with a Muted Inflammatory Response The American Journal of Pathology. Jan, 2022 | Pubmed ID: 34627751 An Improved At-Labeled Agent for PSMA-Targeted α-Therapy Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2022 | Pubmed ID: 34088772 Dual-Modality PET-SPECT Image-Guided Pretargeting Delivery in HER2(+) Breast Cancer Models Biomacromolecules. Nov, 2021 | Pubmed ID: 34704434 CRYβB2 Enhances Tumorigenesis Through Upregulation of Nucleolin in Triple Negative Breast Cancer Oncogene. Sep, 2021 | Pubmed ID: 34341513 GPCR-ErbB Transactivation Pathways and Clinical Implications Cellular Signalling. Oct, 2021 | Pubmed ID: 34303814 A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes Cancer Discovery. May, 2021 | Pubmed ID: 33408241 Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy Molecular Pharmaceutics. 09, 2020 | Pubmed ID: 32803984 Prenatal Stress Enhances NNK-induced Lung Tumors in A/J Mice Carcinogenesis. Apr, 2020 | Pubmed ID: 32249286 Fropofol Prevents Disease Progression in Mice with Hypertrophic Cardiomyopathy Cardiovascular Research. May, 2020 | Pubmed ID: 31424496 FATAL RANAVIRUS INFECTION IN A GROUP OF ZOO-HOUSED MELLER'S CHAMELEONS () Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. Sep, 2019 | Pubmed ID: 33517641 Enhancing the Abscopal Effect of Radiation and Immune Checkpoint Inhibitor Therapies with Magnetic Nanoparticle Hyperthermia in a Model of Metastatic Breast Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 11, 2019 | Pubmed ID: 31795835 Engineered Nanoparticles for Systemic SiRNA Delivery to Malignant Brain Tumours Nanoscale. Nov, 2019 | Pubmed ID: 31612183 Noninvasive Monitoring of Allogeneic Stem Cell Delivery with Dual-Modality Imaging-Visible Microcapsules in a Rabbit Model of Peripheral Arterial Disease Stem Cells International. 2019 | Pubmed ID: 31001343 Stationary Phase Persister/biofilm Microcolony of Borrelia Burgdorferi Causes More Severe Disease in a Mouse Model of Lyme Arthritis: Implications for Understanding Persistence, Post-treatment Lyme Disease Syndrome (PTLDS), and Treatment Failure Discovery Medicine. Mar, 2019 | Pubmed ID: 30946803 RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3 Cancer Research. Nov, 2016 | Pubmed ID: 27634756 Echocardiographic Characterization of a Murine Model of Hypertrophic Obstructive Cardiomyopathy Induced by Cardiac-specific Overexpression of Epidermal Growth Factor Receptor 2 Comparative Medicine. 2016 | Pubmed ID: 27538857 An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor Chembiochem : a European Journal of Chemical Biology. Oct, 2016 | Pubmed ID: 27432157 A Preclinical Murine Model for the Early Detection of Radiation-induced Brain Injury Using Magnetic Resonance Imaging and Behavioral Tests for Learning and Memory: with Applications for the Evaluation of Possible Stem Cell Imaging Agents and Therapies Journal of Neuro-oncology. 06, 2016 | Pubmed ID: 27021492 Bidirectional Cross-regulation Between ErbB2 and β-adrenergic Signalling Pathways Cardiovascular Research. Mar, 2016 | Pubmed ID: 26692570 Imaging Transplanted Stem Cells in Real Time Using an MRI Dual-contrast Method Scientific Reports. Sep, 2015 | Pubmed ID: 26330231 Electrocardiographic Characterization of Cardiac Hypertrophy in Mice That Overexpress the ErbB2 Receptor Tyrosine Kinase Comparative Medicine. Aug, 2015 | Pubmed ID: 26310459 ErbB2 Overexpression Upregulates Antioxidant Enzymes, Reduces Basal Levels of Reactive Oxygen Species, and Protects Against Doxorubicin Cardiotoxicity American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2015 | Pubmed ID: 26254336 Targeting DDX3 with a Small Molecule Inhibitor for Lung Cancer Therapy EMBO Molecular Medicine. May, 2015 | Pubmed ID: 25820276 Parkin-independent Mitophagy Requires Drp1 and Maintains the Integrity of Mammalian Heart and Brain The EMBO Journal. Dec, 2014 | Pubmed ID: 25349190 A Novel Viscous Dissecting Gel for Endoscopic Submucosal Dissection: a Prospective Survival Study in a Porcine Model Endoscopy. Jul, 2014 | Pubmed ID: 24770967 Fused X-ray and MR Imaging Guidance of Intrapericardial Delivery of Microencapsulated Human Mesenchymal Stem Cells in Immunocompetent Swine Radiology. Aug, 2014 | Pubmed ID: 24749713 Geranylgeranylacetone Blocks Doxorubicin-induced Cardiac Toxicity and Reduces Cancer Cell Growth and Invasion Through RHO Pathway Inhibition Molecular Cancer Therapeutics. Jul, 2014 | Pubmed ID: 24737026 Generation of a Cre Recombinase-conditional Nos1ap Over-expression Transgenic Mouse Biotechnology Letters. Jun, 2014 | Pubmed ID: 24563304 A Pkd1-Fbn1 Genetic Interaction Implicates TGF-β Signaling in the Pathogenesis of Vascular Complications in Autosomal Dominant Polycystic Kidney Disease Journal of the American Society of Nephrology : JASN. Jan, 2014 | Pubmed ID: 24071006 Fatal Eosinophilic Myocarditis Develops in the Absence of IFN-γ and IL-17A Journal of Immunology (Baltimore, Md. : 1950). Oct, 2013 | Pubmed ID: 24048893 Endocardial Endothelium is a Key Determinant of Force-frequency Relationship in Rat Ventricular Myocardium Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2013 | Pubmed ID: 23703113 Anti-hypertrophic and Anti-oxidant Effect of Beta3-adrenergic Stimulation in Myocytes Requires Differential Neuronal NOS Phosphorylation Journal of Molecular and Cellular Cardiology. Sep, 2013 | Pubmed ID: 23643588 Beneficial Cardiac Effects of Caloric Restriction Are Lost with Age in a Murine Model of Obesity Journal of Cardiovascular Translational Research. Jun, 2013 | Pubmed ID: 23456569 A Composite Polymer Nanoparticle Overcomes Multidrug Resistance and Ameliorates Doxorubicin-associated Cardiomyopathy Oncotarget. Jun, 2012 | Pubmed ID: 22791660 Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism: Role of Neuronal Nitric Oxide Synthase Journal of the American College of Cardiology. May, 2012 | Pubmed ID: 22624839 X-ray-visible Microcapsules Containing Mesenchymal Stem Cells Improve Hind Limb Perfusion in a Rabbit Model of Peripheral Arterial Disease Stem Cells (Dayton, Ohio). Jun, 2012 | Pubmed ID: 22438076 Endothelial Expression of Hypoxia-inducible Factor 1 Protects the Murine Heart and Aorta from Pressure Overload by Suppression of TGF-β Signaling Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22403061 Dose-dependent Depth of Tissue Injury with Carbon Dioxide Cryotherapy in Porcine GI Tract Gastrointestinal Endoscopy. May, 2012 | Pubmed ID: 22301345 Acute Renal Venous Obstruction is More Detrimental to the Kidney Than Arterial Occlusion: Implication for Murine Models of Acute Kidney Injury American Journal of Physiology. Renal Physiology. Mar, 2012 | Pubmed ID: 22114209 쥐에서 바이러스 성 심근 염의 Th2 규정: 만성 질병 진행에 TRIF 대 Tlr3에 대 한 서로 다른 역할 Clinical & Developmental Immunology. 2012 | Pubmed ID: 22013485 The Innate Immune Response to Coxsackievirus B3 Predicts Progression to Cardiovascular Disease and Heart Failure in Male Mice Biology of Sex Differences. Feb, 2011 | Pubmed ID: 21338512 Myocardial Remodeling is Controlled by Myocyte-targeted Gene Regulation of Phosphodiesterase Type 5 Journal of the American College of Cardiology. Dec, 2010 | Pubmed ID: 20970280 Gastric Wall Healing After NOTES Procedures: Closure with Endoscopic Clips Provides Superior Histological Outcome Compared with Threaded Tags Closure Gastrointestinal Endoscopy. Aug, 2010 | Pubmed ID: 20674622 Interleukin-17A is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy Circulation Research. May, 2010 | Pubmed ID: 20378858 Evidence for a Role of Immunoproteasomes in Regulating Cardiac Muscle Mass in Diabetic Mice Journal of Molecular and Cellular Cardiology. Jul, 2010 | Pubmed ID: 20153750 Adverse Ventricular Remodeling and Exacerbated NOS Uncoupling from Pressure-overload in Mice Lacking the Beta3-adrenoreceptor Journal of Molecular and Cellular Cardiology. Nov, 2009 | Pubmed ID: 19766235 Regulator of G Protein Signaling 2 Mediates Cardiac Compensation to Pressure Overload and Antihypertrophic Effects of PDE5 Inhibition in Mice The Journal of Clinical Investigation. Feb, 2009 | Pubmed ID: 19127022 Phosphodiesterase 5 Inhibition Blocks Pressure Overload-induced Cardiac Hypertrophy Independent of the Calcineurin Pathway Cardiovascular Research. Feb, 2009 | Pubmed ID: 19029137 Detection of Dose Response in Chronic Doxorubicin-mediated Cell Death with Cardiac Technetium 99m Annexin V Single-photon Emission Computed Tomography Molecular Imaging. May-Jun, 2008 | Pubmed ID: 19123983 고슴도치 신호 Bioavailable 작은 분자 억제 물 종양 개시와 췌 장 암에서 전이 억제 하는 구두 Molecular Cancer Therapeutics. Sep, 2008 | Pubmed ID: 18790753 Etanercept, a TNF-alpha Binding Agent, is Ineffective in the Prevention of Post-ERCP Pancreatitis in Canines JOP : Journal of the Pancreas. 2008 | Pubmed ID: 18648137 Interleukin-13 Protects Against Experimental Autoimmune Myocarditis by Regulating Macrophage Differentiation The American Journal of Pathology. May, 2008 | Pubmed ID: 18403598 Spontaneous Lesions in the Reproductive Tract and Mammary Gland of Female Non-human Primates Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Apr, 2007 | Pubmed ID: 17342758 고슴도치 신호 봉쇄 췌장암 침공과 전이 억제: 조합 단단한 암 치료의 새로운 패러다임 Cancer Research. Mar, 2007 | Pubmed ID: 17332349 Heat Shock Protein 90 and ErbB2 in the Cardiac Response to Doxorubicin Injury Cancer Research. Feb, 2007 | Pubmed ID: 17308081 Aging Impairs the Beneficial Effect of Granulocyte Colony-stimulating Factor and Stem Cell Factor on Post-myocardial Infarction Remodeling Circulation Research. Sep, 2006 | Pubmed ID: 16873716 Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome Science (New York, N.Y.). Apr, 2006 | Pubmed ID: 16601194 조건에 따라 Vivo에서 비활성화 될 수 있습니다 Pkd1의 기능 Floxed 대립 유전자 Journal of the American Society of Nephrology : JASN. Dec, 2004 | Pubmed ID: 15579506 TGF-beta-dependent Pathogenesis of Mitral Valve Prolapse in a Mouse Model of Marfan Syndrome The Journal of Clinical Investigation. Dec, 2004 | Pubmed ID: 15546004 Protection from Doxorubicin-induced Cardiac Toxicity in Mice with a Null Allele of Carbonyl Reductase 1 Cancer Research. Oct, 2003 | Pubmed ID: 14583452 Mitochondrial Toxin 3-nitropropionic Acid Induces Cardiac and Neurotoxicity Differentially in Mice The American Journal of Pathology. Oct, 2001 | Pubmed ID: 11583977 Apoptosis Has a Prolonged Role in the Neurodegeneration After Hypoxic Ischemia in the Newborn Rat The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2000 | Pubmed ID: 11050120 Induction of STK11-dependent Cytoprotective Autophagy in Breast Cancer Cells Upon Honokiol Treatment Cell Death Discovery. | Pubmed ID: 32963809 마우스에서 종양 억제인자 Arid1a 및 Pten 의 Pax8 지시 결실에서 자궁내막암 진행의 비침습적 초음파 평가 Rachel Vistein1, Briana Winer2, Stephanie Myers1,3, Juliane Liberto4, Shun Ishiyama1,5,6, Xin Guo1, Harumi Saeki7, Tian-Li Wang4,8, Ie-Ming Shih2,4,8, Kathleen Gabrielson1,4,8 1Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, 2Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, 3Texas Tech University School of Veterinary Medicine, 4Department of Pathology, Johns Hopkins University School of Medicine, 5Department of Surgery, Johns Hopkins University School of Medicine, 6Department of Coloproctological Surgery, Juntendo University School of Medicine, 7Department of Human Pathology, Juntendo University School of Medicine, 8Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University JoVE 64732 Cancer Research 전이율을 제어하는 절단을 가진 신제닉 직소 성 골육종 스프라그 Dawley 쥐 모델 Shun Ishiyama1,2,3,4, Casey Kissel5, Xin Guo1, Alexis Howard6, Harumi Saeki7, Tomoaki Ito8, Polina Sysa-Shah9, Hajime Orita10, Kazuhiro Sakamoto4, Kathleen Gabrielson1,2 1Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 3Department of Surgery, Johns Hopkins University School of Medicine, 4Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 5Program for Comparative Medicine, Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, 6Tuskegee College of Veterinary Medicine, 7Department of Human Pathology, Juntendo University Faculty of Medicine, 8Department of Surgery, Juntendo University Shizuoka Hospital, Juntendo University School of Medicine, 9Department of Urology, The Johns Hopkins School of Medicine, 10Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Faculty of Medicine JoVE 62139 Cancer Research
마우스에서 종양 억제인자 Arid1a 및 Pten 의 Pax8 지시 결실에서 자궁내막암 진행의 비침습적 초음파 평가 Rachel Vistein1, Briana Winer2, Stephanie Myers1,3, Juliane Liberto4, Shun Ishiyama1,5,6, Xin Guo1, Harumi Saeki7, Tian-Li Wang4,8, Ie-Ming Shih2,4,8, Kathleen Gabrielson1,4,8 1Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, 2Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, 3Texas Tech University School of Veterinary Medicine, 4Department of Pathology, Johns Hopkins University School of Medicine, 5Department of Surgery, Johns Hopkins University School of Medicine, 6Department of Coloproctological Surgery, Juntendo University School of Medicine, 7Department of Human Pathology, Juntendo University School of Medicine, 8Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University JoVE 64732 Cancer Research
전이율을 제어하는 절단을 가진 신제닉 직소 성 골육종 스프라그 Dawley 쥐 모델 Shun Ishiyama1,2,3,4, Casey Kissel5, Xin Guo1, Alexis Howard6, Harumi Saeki7, Tomoaki Ito8, Polina Sysa-Shah9, Hajime Orita10, Kazuhiro Sakamoto4, Kathleen Gabrielson1,2 1Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 3Department of Surgery, Johns Hopkins University School of Medicine, 4Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 5Program for Comparative Medicine, Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, 6Tuskegee College of Veterinary Medicine, 7Department of Human Pathology, Juntendo University Faculty of Medicine, 8Department of Surgery, Juntendo University Shizuoka Hospital, Juntendo University School of Medicine, 9Department of Urology, The Johns Hopkins School of Medicine, 10Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Faculty of Medicine JoVE 62139 Cancer Research
