Kathy Steece-Collier

Publications

• α-Synuclein Antisense Oligonucleotides As a Disease-modifying Therapy for Parkinson's Disease
  JCI Insight. 03, 2021  |   Pubmed ID: 33682798
• Striatal Afferent BDNF is Disrupted by Synucleinopathy and Partially Restored by STN DBS
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2021  |   Pubmed ID: 33472823
• The BDNF Val66Met Polymorphism (rs6265) Enhances Dopamine Neuron Graft Efficacy and Side-effect Liability in Rs6265 Knock-in Rats
  Neurobiology of Disease. Jan, 2021  |   Pubmed ID: 33188920
• Preclinical Evidence in Support of Repurposing Sub-anesthetic Ketamine As a Treatment for L-DOPA-induced Dyskinesia
  Experimental Neurology. 11, 2020  |   Pubmed ID: 32717354
• Striatal Nurr1, but Not FosB Expression Links a Levodopa-induced Dyskinesia Phenotype to Genotype in Fisher 344 Vs. Lewis Hemiparkinsonian Rats
  Experimental Neurology. 08, 2020  |   Pubmed ID: 32387398
• Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 04, 2020  |   Pubmed ID: 32238479
• Cell Therapy for Parkinson's Disease: Why It Doesn't Work Every Time
  Movement Disorders : Official Journal of the Movement Disorder Society. 08, 2019  |   Pubmed ID: 31234239
• Genetic Silencing of Striatal CaV1.3 Prevents and Ameliorates Levodopa Dyskinesia
  Movement Disorders : Official Journal of the Movement Disorder Society. 05, 2019  |   Pubmed ID: 31002755
• Regulation of Dopamine Neurotransmission from Serotonergic Neurons by Ectopic Expression of the Dopamine D2 Autoreceptor Blocks Levodopa-induced Dyskinesia
  Acta Neuropathologica Communications. 01, 2019  |   Pubmed ID: 30646956
• Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression
  Scientific Reports. Nov, 2017  |   Pubmed ID: 29180681
• Subthalamic Nucleus Deep Brain Stimulation Employs TrkB Signaling for Neuroprotection and Functional Restoration
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 07, 2017  |   Pubmed ID: 28607168
• Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic
  Journal of Clinical & Cellular Immunology. Dec, 2016  |   Pubmed ID: 28111608
• Impact of Age and Vector Construct on Striatal and Nigral Transgene Expression
  Molecular Therapy. Methods & Clinical Development. 2016  |   Pubmed ID: 27933309
• Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and L-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2015  |   Pubmed ID: 26558771
• Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration
  PloS One. 2015  |   Pubmed ID: 26340267
• High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine
  PloS One. 2015  |   Pubmed ID: 26222442
• Pathophysiology of L-dopa-induced Motor and Non-motor Complications in Parkinson's Disease
  Progress in Neurobiology. Sep, 2015  |   Pubmed ID: 26209473
• Intrastriatal Injection of Pre-formed Mouse α-synuclein Fibrils into Rats Triggers α-synuclein Pathology and Bilateral Nigrostriatal Degeneration
  Neurobiology of Disease. Oct, 2015  |   Pubmed ID: 26093169
• The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-hydroxydopamine Reveals Significant Upregulation of Regeneration-associated Genes
  PloS One. 2015  |   Pubmed ID: 25992874
• Interrogating the Aged Striatum: Robust Survival of Grafted Dopamine Neurons in Aging Rats Produces Inferior Behavioral Recovery and Evidence of Impaired Integration
  Neurobiology of Disease. May, 2015  |   Pubmed ID: 25771169
• Recombinant Adenoassociated Virus 2/5-mediated Gene Transfer is Reduced in the Aged Rat Midbrain
  Neurobiology of Aging. Feb, 2015  |   Pubmed ID: 25457558
• Chronic Amitriptyline Treatment Attenuates Nigrostriatal Degeneration and Significantly Alters Trophic Support in a Rat Model of Parkinsonism
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Mar, 2015  |   Pubmed ID: 25267343
• Aberrant Restoration of Spines and Their Synapses in L-DOPA-induced Dyskinesia: Involvement of Corticostriatal but Not Thalamostriatal Synapses
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2013  |   Pubmed ID: 23843533
• Advances in Thin Tissue Golgi-Cox Impregnation: Fast, Reliable Methods for Multi-assay Analyses in Rodent and Non-human Primate Brain
  Journal of Neuroscience Methods. Mar, 2013  |   Pubmed ID: 23313849
• Anatomy of Graft-induced Dyskinesias: Circuit Remodeling in the Parkinsonian Striatum
  Basal Ganglia. Mar, 2012  |   Pubmed ID: 22712056
• Subthalamic Nucleus Stimulation Increases Brain Derived Neurotrophic Factor in the Nigrostriatal System and Primary Motor Cortex
  Journal of Parkinson's Disease. May, 2011  |   Pubmed ID: 22328911
• Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2011  |   Pubmed ID: 22008908
• Transfer of Host-derived α Synuclein to Grafted Dopaminergic Neurons in Rat
  Neurobiology of Disease. Sep, 2011  |   Pubmed ID: 21600984