Kelvin Yen Leonard Davis School of Gerontology University of Southern California Biography Publications Institution JoVE Articles Kelvin Yen has not added a biography. If you are Kelvin Yen and would like to personalize this page please email our Author Liaison for assistance. Publications The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity Scientific Reports. Aug, 2017 | Pubmed ID: 28798389 Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production Cell Metabolism. Jun, 2017 | Pubmed ID: 28591635 Mitochondrially Derived Peptides As Novel Regulators of Metabolism The Journal of Physiology. Jun, 2017 | Pubmed ID: 28574175 The Mitochondrial-derived Peptide Humanin Activates the ERK1/2, AKT, and STAT3 Signaling Pathways and Has Age-dependent Signaling Differences in the Hippocampus Oncotarget. Jul, 2016 | Pubmed ID: 27384491 Naturally Occurring Mitochondrial-derived Peptides Are Age-dependent Regulators of Apoptosis, Insulin Sensitivity, and Inflammatory Markers Aging. Apr, 2016 | Pubmed ID: 27070352 The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction Investigative Ophthalmology & Visual Science. Mar, 2016 | Pubmed ID: 26990160 Uncoupling Lifespan and Healthspan in Caenorhabditis Elegans Longevity Mutants Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25561524 IGF-I Regulates the Age-dependent Signaling Peptide Humanin Aging Cell. Oct, 2014 | Pubmed ID: 25040290 Humanin: a Harbinger of Mitochondrial-derived Peptides? Trends in Endocrinology and Metabolism: TEM. May, 2013 | Pubmed ID: 23402768 The Emerging Role of the Mitochondrial-derived Peptide Humanin in Stress Resistance Journal of Molecular Endocrinology. Feb, 2013 | Pubmed ID: 23239898 Hypothalamic Fkbp51 is Induced by Fasting, and Elevated Hypothalamic Expression Promotes Obese Phenotypes American Journal of Physiology. Endocrinology and Metabolism. Apr, 2012 | Pubmed ID: 22318949 FDA-approved Drugs That Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity PloS One. 2011 | Pubmed ID: 22114686 PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism PLoS Genetics. Apr, 2011 | Pubmed ID: 21533078 DAF-16/Forkhead Box O Transcription Factor: Many Paths to a Single Fork(head) in the Road Antioxidants & Redox Signaling. Feb, 2011 | Pubmed ID: 20673162 A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis Elegans Using Label and Label-free Methods PloS One. Sep, 2010 | Pubmed ID: 20862331 A New DAF-16 Isoform Regulates Longevity Nature. Jul, 2010 | Pubmed ID: 20613724 Evidence for Only Two Independent Pathways for Decreasing Senescence in Caenorhabditis Elegans Age (Dordrecht, Netherlands). Mar, 2010 | Pubmed ID: 19662517 Role of CBP and SATB-1 in Aging, Dietary Restriction, and Insulin-like Signaling PLoS Biology. Nov, 2009 | Pubmed ID: 19924292 Converging Pathways in Lifespan Regulation Current Biology : CB. Aug, 2009 | Pubmed ID: 19674551 SOD Isoforms Play No Role in Lifespan in Ad Lib or Dietary Restricted Conditions, but Mutational Inactivation of SOD-1 Reduces Life Extension by Cold Mechanisms of Ageing and Development. Mar, 2009 | Pubmed ID: 19059428 Validated Analysis of Mortality Rates Demonstrates Distinct Genetic Mechanisms That Influence Lifespan Experimental Gerontology. Dec, 2008 | Pubmed ID: 18832022 Chemosensory and Caloric Mechanisms Influence Distinct Components of Mortality Rate Experimental Gerontology. Dec, 2008 | Pubmed ID: 18790043 Low-carbohydrate Diets Cause Obesity, Low-carbohydrate Diets Reverse Obesity: a Metabolic Mechanism Resolving the Paradox Appetite. Mar, 2007 | Pubmed ID: 17141367 Secrets of the Lac Operon. Glucose Hysteresis As a Mechanism in Dietary Restriction, Aging and Disease Interdisciplinary Topics in Gerontology. 2007 | Pubmed ID: 17063032 Impaired Glucose Signaling As a Cause of Obesity and the Metabolic Syndrome: the Glucoadipostatic Hypothesis Physiology & Behavior. May, 2005 | Pubmed ID: 15924903 Lifespan is Not Determined by Metabolic Rate: Evidence from Fishes and C. Elegans Experimental Gerontology. Jun, 2004 | Pubmed ID: 15217699 Mining Microarrays for Metabolic Meaning: Nutritional Regulation of Hypothalamic Gene Expression Neurochemical Research. Jun, 2004 | Pubmed ID: 15176466 Subcellular Fractionation for ERK Activation Upon Mitochondrial-derived Peptide Treatment Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology
Subcellular Fractionation for ERK Activation Upon Mitochondrial-derived Peptide Treatment Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology
