Kendal Broadie Biography Publications JoVE Articles Kendal Broadie has not added a biography. If you are Kendal Broadie and would like to personalize this page please email our Author Liaison for assistance. Publications Use-dependent, Untapped Dual Kinase Signaling Localized in Brain Learning Circuitry The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2024 | Pubmed ID: 38267256 Muscle Cofilin Alters Neuromuscular Junction Postsynaptic Development to Strengthen Functional Neurotransmission BioRxiv : the Preprint Server for Biology. Nov, 2023 | Pubmed ID: 38045306 Glycosphingolipids Are Linked to Elevated Neurotransmission and Neurodegeneration in a Drosophila Model of Niemann Pick Type C Disease Models & Mechanisms. Oct, 2023 | Pubmed ID: 37815467 Fragile X Mental Retardation Protein Coordinates Neuron-to-glia Communication for Clearance of Developmentally Transient Brain Neurons Proceedings of the National Academy of Sciences of the United States of America. Mar, 2023 | Pubmed ID: 36920921 FMRP Activity and Control of Csw/SHP2 Translation Regulate MAPK-dependent Synaptic Transmission PLoS Biology. Jan, 2023 | Pubmed ID: 36701299 Dysregulation of BMP, Wnt, and Insulin Signaling in Fragile X Syndrome Frontiers in Cell and Developmental Biology. 2022 | Pubmed ID: 35880195 RNA-binding FMRP and Staufen Sequentially Regulate the Coracle Scaffold to Control Synaptic Glutamate Receptor and Bouton Development Development (Cambridge, England). May, 2022 | Pubmed ID: 35394012 Temporally and Spatially Localized PKA Activity Within Learning and Memory Circuitry Regulated by Network Feedback ENeuro. 2022 | Pubmed ID: 35301221 Secreted C-type Lectin Regulation of Neuromuscular Junction Synaptic Vesicle Dynamics Modulates Coordinated Movement Journal of Cell Science. May, 2021 | Pubmed ID: 33973638 Neuronal Fragile X Mental Retardation Protein Activates Glial Insulin Receptor Mediated PDF-Tri Neuron Developmental Clearance Nature Communications. Feb, 2021 | Pubmed ID: 33608547 Neuron-Specific FMRP Roles in Experience-Dependent Remodeling of Olfactory Brain Innervation During an Early-Life Critical Period The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2021 | Pubmed ID: 33402421 FMRP-PKA Activity Negative Feedback Regulates RNA Binding-Dependent Fibrillation in Brain Learning and Memory Circuitry Cell Reports. Oct, 2020 | Pubmed ID: 33053340 Extracellular Heparan Sulfate Proteoglycans and Glycan-binding Lectins Orchestrate -synaptic Signaling Journal of Cell Science. Aug, 2020 | Pubmed ID: 32788209 Genetic Background Mutations Drive Neural Circuit Hyperconnectivity in a Fragile X Syndrome Model BMC Biology. Jul, 2020 | Pubmed ID: 32731855 Carrier of Wingless (Cow) Regulation of Neuromuscular Junction Development ENeuro. 2020 | Pubmed ID: 32024666 Fragile X Mental Retardation Protein Positively Regulates PKA Anchor Rugose and PKA Activity to Control Actin Assembly in Learning/memory Circuitry Neurobiology of Disease. Jul, 2019 | Pubmed ID: 30771457 Activity-Dependent Remodeling of Olfactory Sensory Neuron Brain Innervation During an Early-Life Critical Period The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2019 | Pubmed ID: 30755492 Newly Identified Electrically Coupled Neurons Support Development of the Giant Fiber Model Circuit ENeuro. 2018 | Pubmed ID: 30627638 Neuronal Activity Drives FMRP- and HSPG-dependent Matrix Metalloproteinase Function Required for Rapid Synaptogenesis Science Signaling. Nov, 2017 | Pubmed ID: 29114039 Fragile X Mental Retardation Protein Restricts Small Dye Iontophoresis Entry into Central Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2017 | Pubmed ID: 28887386 Notum Coordinates Synapse Development Via Extracellular Regulation of Wingless Trans-synaptic Signaling Development (Cambridge, England). 10, 2017 | Pubmed ID: 28860114 Multifarious Functions of the Fragile X Mental Retardation Protein Trends in Genetics : TIG. 10, 2017 | Pubmed ID: 28826631 ESCRT-III Membrane Trafficking Misregulation Contributes To Fragile X Syndrome Synaptic Defects Scientific Reports. Aug, 2017 | Pubmed ID: 28819289 Fragile X Mental Retardation Protein Requirements in Activity-Dependent Critical Period Neural Circuit Refinement Current Biology : CB. Aug, 2017 | Pubmed ID: 28756946 Secreted Tissue Inhibitor of Matrix Metalloproteinase Restricts -synaptic Signaling to Coordinate Synaptogenesis Journal of Cell Science. Jul, 2017 | Pubmed ID: 28576972 Neural Circuits: Reduced Inhibition in Fragile X Syndrome Current Biology : CB. Apr, 2017 | Pubmed ID: 28441561 Developmental Experience-dependent Plasticity in the First Synapse of the Drosophila Olfactory Circuit Journal of Neurophysiology. Dec, 2016 | Pubmed ID: 27683892 Coordinated Movement, Neuromuscular Synaptogenesis and Trans-synaptic Signaling Defects in Drosophila Galactosemia Models Human Molecular Genetics. 09, 2016 | Pubmed ID: 27466186 Synaptic Roles for Phosphomannomutase Type 2 in a New Drosophila Congenital Disorder of Glycosylation Disease Model Disease Models & Mechanisms. 05, 2016 | Pubmed ID: 26940433 Neuron Class-specific Requirements for Fragile X Mental Retardation Protein in Critical Period Development of Calcium Signaling in Learning and Memory Circuitry Neurobiology of Disease. May, 2016 | Pubmed ID: 26851502 A Fully Automated Drosophila Olfactory Classical Conditioning and Testing System for Behavioral Learning and Memory Assessment Journal of Neuroscience Methods. Mar, 2016 | Pubmed ID: 26703418 Two Classes of Matrix Metalloproteinases Reciprocally Regulate Synaptogenesis Development (Cambridge, England). Jan, 2016 | Pubmed ID: 26603384 Activity-dependent FMRP Requirements in Development of the Neural Circuitry of Learning and Memory Development (Cambridge, England). Apr, 2015 | Pubmed ID: 25804740 Overelaborated Synaptic Architecture and Reduced Synaptomatrix Glycosylation in a Drosophila Classic Galactosemia Disease Model Disease Models & Mechanisms. Dec, 2014 | Pubmed ID: 25326312 Two Protein N-acetylgalactosaminyl Transferases Regulate Synaptic Plasticity by Activity-dependent Regulation of Integrin Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2014 | Pubmed ID: 25253852 GABAergic Circuit Dysfunction in the Drosophila Fragile X Syndrome Model Neurobiology of Disease. May, 2014 | Pubmed ID: 24423648 Structure-function Analysis of Endogenous Lectin Mind-the-gap in Synaptogenesis Developmental Neurobiology. Jan, 2012 | Pubmed ID: 22234957 In Vivo Neuronal Function of the Fragile X Mental Retardation Protein is Regulated by Phosphorylation Human Molecular Genetics. Feb, 2012 | Pubmed ID: 22080836 Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome Results and Problems in Cell Differentiation. 2012 | Pubmed ID: 22009350 Glycosylated Synaptomatrix Regulation of Trans-synaptic Signaling Developmental Neurobiology. Jan, 2012 | Pubmed ID: 21509945 Extracellular Matrix and Its Receptors in Drosophila Neural Development Developmental Neurobiology. Nov, 2011 | Pubmed ID: 21688401 Neural Circuit Architecture Defects in a Drosophila Model of Fragile X Syndrome Are Alleviated by Minocycline Treatment and Genetic Removal of Matrix Metalloproteinase Disease Models & Mechanisms. Sep-Oct, 2011 | Pubmed ID: 21669931 Drosophila Modeling of Heritable Neurodevelopmental Disorders Current Opinion in Neurobiology. Dec, 2011 | Pubmed ID: 21596554 Fragile X Mental Retardation Protein is Required for Programmed Cell Death and Clearance of Developmentally-transient Peptidergic Neurons Developmental Biology. Aug, 2011 | Pubmed ID: 21596027 The Fragile X Mental Retardation Protein Developmentally Regulates the Strength and Fidelity of Calcium Signaling in Drosophila Mushroom Body Neurons Neurobiology of Disease. Jan, 2011 | Pubmed ID: 20843478 Genetic Controls Balancing Excitatory and Inhibitory Synaptogenesis in Neurodevelopmental Disorder Models Frontiers in Synaptic Neuroscience. 2010 | Pubmed ID: 21423490 The Cdc42-selective GAP Rich Regulates Postsynaptic Development and Retrograde BMP Transsynaptic Signaling The Journal of Cell Biology. Nov, 2010 | Pubmed ID: 21041451 Drosophila Rolling Blackout Displays Lipase Domain-dependent and -independent Endocytic Functions Downstream of Dynamin Traffic (Copenhagen, Denmark). Dec, 2010 | Pubmed ID: 21029287 Anterograde Jelly Belly Ligand to Alk Receptor Signaling at Developing Synapses is Regulated by Mind the Gap Development (Cambridge, England). Oct, 2010 | Pubmed ID: 20876658 The Nonsense-mediated Decay Pathway Maintains Synapse Architecture and Synaptic Vesicle Cycle Efficacy Journal of Cell Science. Oct, 2010 | Pubmed ID: 20826458 Fragile X Mental Retardation Protein Has a Unique, Evolutionarily Conserved Neuronal Function Not Shared with FXR1P or FXR2P Disease Models & Mechanisms. Jul-Aug, 2010 | Pubmed ID: 20442204 Structural Mass Spectrometry Analysis of Lipid Changes in a Drosophila Epilepsy Model Brain Molecular BioSystems. Jun, 2010 | Pubmed ID: 20379606 Temporal Requirements of the Fragile X Mental Retardation Protein in Modulating Circadian Clock Circuit Synaptic Architecture Frontiers in Neural Circuits. 2009 | Pubmed ID: 19738924 Activity-dependent Modulation of Neural Circuit Synaptic Connectivity Frontiers in Molecular Neuroscience. 2009 | Pubmed ID: 19668708 Presynaptic Secretion of Mind-the-gap Organizes the Synaptic Extracellular Matrix-integrin Interface and Postsynaptic Environments Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2009 | Pubmed ID: 19235718 The Fragile X Mental Retardation Protein in Circadian Rhythmicity and Memory Consolidation Molecular Neurobiology. Apr, 2009 | Pubmed ID: 19214804 Rolling Blackout is Required for Bulk Endocytosis in Non-neuronal Cells and Neuronal Synapses Journal of Cell Science. Jan, 2009 | Pubmed ID: 19066280 Metabotropic Glutamate Receptor-mediated Use-dependent Down-regulation of Synaptic Excitability Involves the Fragile X Mental Retardation Protein Journal of Neurophysiology. Feb, 2009 | Pubmed ID: 19036865 Motor Deficit in a Drosophila Model of Mucolipidosis Type IV Due to Defective Clearance of Apoptotic Cells Cell. Nov, 2008 | Pubmed ID: 19041749 Two Peptide Transmitters Co-packaged in a Single Neurosecretory Vesicle Peptides. Dec, 2008 | Pubmed ID: 18848852 Excess Protein Synthesis in Drosophila Fragile X Mutants Impairs Long-term Memory Nature Neuroscience. Oct, 2008 | Pubmed ID: 18776892 Neuronal Loss of Drosophila NPC1a Causes Cholesterol Aggregation and Age-progressive Neurodegeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579730 Temporal Requirements of the Fragile X Mental Retardation Protein in the Regulation of Synaptic Structure Development (Cambridge, England). Aug, 2008 | Pubmed ID: 18579676 Presynaptic Calcium Channel Localization and Calcium-dependent Synaptic Vesicle Exocytosis Regulated by the Fuseless Protein The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18385325 Mutational Analysis Establishes a Critical Role for the N Terminus of Fragile X Mental Retardation Protein FMRP The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2008 | Pubmed ID: 18354025 Drosophila Fragile X Mental Retardation Protein Developmentally Regulates Activity-dependent Axon Pruning Development (Cambridge, England). Apr, 2008 | Pubmed ID: 18321984 Mechanistic Relationships Between Drosophila Fragile X Mental Retardation Protein and Metabotropic Glutamate Receptor A Signaling Molecular and Cellular Neurosciences. Apr, 2008 | Pubmed ID: 18280750 Roles of Ubiquitination at the Synapse Biochimica Et Biophysica Acta. Aug, 2008 | Pubmed ID: 18222124 CNS-derived Glia Ensheath Peripheral Nerves and Mediate Motor Root Development Nature Neuroscience. Feb, 2008 | Pubmed ID: 18176560 Drosophila Fragile X Mental Retardation Protein and Metabotropic Glutamate Receptor A Convergently Regulate the Synaptic Ratio of Ionotropic Glutamate Receptor Subclasses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2007 | Pubmed ID: 17989302 Presynaptic Establishment of the Synaptic Cleft Extracellular Matrix is Required for Post-synaptic Differentiation Genes & Development. Oct, 2007 | Pubmed ID: 17901219 Proteasome Function is Required to Maintain Muscle Cellular Architecture Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Nov, 2007 | Pubmed ID: 17523916 The Ubiquitin-proteasome System Postsynaptically Regulates Glutamatergic Synaptic Function Molecular and Cellular Neurosciences. May, 2007 | Pubmed ID: 17363264 In Vivo Assay of Presynaptic Microtubule Cytoskeleton Dynamics in Drosophila Journal of Neuroscience Methods. May, 2007 | Pubmed ID: 17331586 Rolling Blackout is Required for Synaptic Vesicle Exocytosis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16510714 An Essential Drosophila Glutamate Receptor Subunit That Functions in Both Central Neuropil and Neuromuscular Junction The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15788777 Translational Complexity of the Fragile X Mental Retardation Protein: Insights from the Fly Molecular Cell. Mar, 2005 | Pubmed ID: 15780932 Lipid Regulation of the Synaptic Vesicle Cycle Nature Reviews. Neuroscience. Feb, 2005 | Pubmed ID: 15685219 Fathoming Fragile X in Fruit Flies Trends in Genetics : TIG. Jan, 2005 | Pubmed ID: 15680513 Protein Expression Profiling of the Drosophila Fragile X Mutant Brain Reveals Up-regulation of Monoamine Synthesis Molecular & Cellular Proteomics : MCP. Mar, 2005 | Pubmed ID: 15634690 The Drosophila Fragile X Gene Negatively Regulates Neuronal Elaboration and Synaptic Differentiation Current Biology : CB. Oct, 2004 | Pubmed ID: 15498496 The Drosophila Metabotropic Glutamate Receptor DmGluRA Regulates Activity-dependent Synaptic Facilitation and Fine Synaptic Morphology The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004 | Pubmed ID: 15483129 Synapse Scaffolding: Intersection of Endocytosis and Growth Current Biology : CB. Oct, 2004 | Pubmed ID: 15458667 Rolling Blackout, a Newly Identified PIP2-DAG Pathway Lipase Required for Drosophila Phototransduction Nature Neuroscience. Oct, 2004 | Pubmed ID: 15361878 Ceramidase Regulates Synaptic Vesicle Exocytosis and Trafficking The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2004 | Pubmed ID: 15356190 Cellular Bases of Activity-dependent Paralysis in Drosophila Stress-sensitive Mutants Journal of Neurobiology. Sep, 2004 | Pubmed ID: 15281071 The Hereditary Spastic Paraplegia Gene, Spastin, Regulates Microtubule Stability to Modulate Synaptic Structure and Function Current Biology : CB. Jul, 2004 | Pubmed ID: 15242610 The Drosophila Fragile X-related Gene Regulates Axoneme Differentiation During Spermatogenesis Developmental Biology. Jun, 2004 | Pubmed ID: 15183715 Axon Pruning: an Active Role for Glial Cells Current Biology : CB. Apr, 2004 | Pubmed ID: 15084298 Techniques to Dissect Cellular and Subcellular Function in the Drosophila Nervous System Methods in Cell Biology. 2003 | Pubmed ID: 12884693 The Ubiquitin Proteasome System Acutely Regulates Presynaptic Protein Turnover and Synaptic Efficacy Current Biology : CB. May, 2003 | Pubmed ID: 12781128 Mutation and Activation of Galpha S Similarly Alters Pre- and Postsynaptic Mechanisms Modulating Neurotransmission Journal of Neurophysiology. May, 2003 | Pubmed ID: 12611964 Synaptic Drosophila UNC-13 is Regulated by Antagonistic G-protein Pathways Via a Proteasome-dependent Degradation Mechanism Journal of Neurobiology. Feb, 2003 | Pubmed ID: 12532395 Cellular Bases of Behavioral Plasticity: Establishing and Modifying Synaptic Circuits in the Drosophila Genetic System Journal of Neurobiology. Jan, 2003 | Pubmed ID: 12486708 Drosophila Sec10 is Required for Hormone Secretion but Not General Exocytosis or Neurotransmission Traffic (Copenhagen, Denmark). Dec, 2002 | Pubmed ID: 12453153 The Synaptic Vesicle Cycle: Exocytosis and Endocytosis in Drosophila and C. Elegans Current Opinion in Neurobiology. Oct, 2002 | Pubmed ID: 12367628 Establishing and Sculpting the Synapse in Drosophila and C. Elegans Current Opinion in Neurobiology. Oct, 2002 | Pubmed ID: 12367627 Living Synaptic Vesicle Marker: Synaptotagmin-GFP Genesis (New York, N.Y. : 2000). Sep-Oct, 2002 | Pubmed ID: 12324970 Electrophysiological Analysis of Synaptic Transmission in Central Neurons of Drosophila Larvae Journal of Neurophysiology. Aug, 2002 | Pubmed ID: 12163536 Response: Meaningless Minis? Trends in Neurosciences. Aug, 2002 | Pubmed ID: 12127747 Integrins Regulate DLG/FAS2 Via a CaM Kinase II-dependent Pathway to Mediate Synapse Elaboration and Stabilization During Postembryonic Development Development (Cambridge, England). Jul, 2002 | Pubmed ID: 12091308 Wrestling with Pleiotropy: Genomic and Topological Analysis of the Yeast Gene Expression Network BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Mar, 2002 | Pubmed ID: 11891763 Developmental Regulation of Glutamate Receptor Field Size by Nonvesicular Glutamate Release Nature Neuroscience. Feb, 2002 | Pubmed ID: 11753421 Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period JoVE 66629 Neuroscience Краситель FM Велоспорт на синапсе: сравнение деполяризации высоким содержанием калия, электрических и Channelrhodopsin стимуляции Danielle L. Kopke1, Kendal Broadie2 1Department of Biological Sciences, Vanderbilt University, 2Departments of Biological Sciences, Pharmacology, Cell and Developmental Biology, Kennedy Center for Research on Human Development, Vanderbilt University and Medical Center JoVE 57765 Neuroscience Электрофизиологические Запись в Drosophila Эмбрионов Kaiyun Chen1, David E. Featherstone1, Kendal Broadie2 1Department of Biological Sciences, University of Illinois, 2Department of Biological Sciences, Vanderbilt University JoVE 1348 Biology Сбор и подготовка Drosophila Эмбрионы для Электрофизиологические Запись и другие процедуры David E. Featherstone1, Kaiyun Chen1, Kendal Broadie2 1Department of Biological Sciences, University of Illinois, 2Department of Biological Sciences, Vanderbilt University JoVE 1347 Biology
Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period JoVE 66629 Neuroscience
Краситель FM Велоспорт на синапсе: сравнение деполяризации высоким содержанием калия, электрических и Channelrhodopsin стимуляции Danielle L. Kopke1, Kendal Broadie2 1Department of Biological Sciences, Vanderbilt University, 2Departments of Biological Sciences, Pharmacology, Cell and Developmental Biology, Kennedy Center for Research on Human Development, Vanderbilt University and Medical Center JoVE 57765 Neuroscience
Электрофизиологические Запись в Drosophila Эмбрионов Kaiyun Chen1, David E. Featherstone1, Kendal Broadie2 1Department of Biological Sciences, University of Illinois, 2Department of Biological Sciences, Vanderbilt University JoVE 1348 Biology
Сбор и подготовка Drosophila Эмбрионы для Электрофизиологические Запись и другие процедуры David E. Featherstone1, Kaiyun Chen1, Kendal Broadie2 1Department of Biological Sciences, University of Illinois, 2Department of Biological Sciences, Vanderbilt University JoVE 1347 Biology
