Klaus Pantel Department of Tumor Biology University Medical Center Hamburg-Eppendorf Biography Publications Institution JoVE Articles Klaus Pantel has not added a biography. If you are Klaus Pantel and would like to personalize this page please email our Author Liaison for assistance. Publications Elevated Serum RAS P21 is an Independent Prognostic Factor in Metastatic Breast Cancer BMC Cancer. May, 2018 | Pubmed ID: 29739347 Blockade of Myeloid-derived Suppressor Cell Expansion with All-trans Retinoic Acid Increases the Efficacy of Anti-angiogenic Therapy Cancer Research. Apr, 2018 | Pubmed ID: 29674477 Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells Developmental Cell. Apr, 2018 | Pubmed ID: 29634935 BET-inhibition by JQ1 Promotes Proliferation and Self-renewal Capacity of Hematopoietic Stem Cells Haematologica. Mar, 2018 | Pubmed ID: 29567778 Improved Risk Stratification by Circulating Tumor Cell Counts in Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2018 | Pubmed ID: 29559560 Advances in Liquid Biopsy Approaches for Early Detection and Monitoring of Cancer Genome Medicine. Mar, 2018 | Pubmed ID: 29558971 Clinical Applications of the CellSearch Platform in Cancer Patients Advanced Drug Delivery Reviews. Jan, 2018 | Pubmed ID: 29355669 In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and Point Mutations in Circulating Tumor Cells Clinical Chemistry. Mar, 2018 | Pubmed ID: 29301749 Disseminated Breast Tumour Cells: Biological and Clinical Meaning Nature Reviews. Clinical Oncology. Mar, 2018 | Pubmed ID: 29158590 Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients Clinical Chemistry. Feb, 2018 | Pubmed ID: 29122836 Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy Cancer Cell. Dec, 2017 | Pubmed ID: 29232552 Evaluation of Serum Epidermal Growth Factor Receptor (EGFR) in Correlation to Circulating Tumor Cells in Patients with Metastatic Breast Cancer Scientific Reports. Dec, 2017 | Pubmed ID: 29229933 Circulating Tumor Cells As Liquid Biomarker for High HCC Recurrence Risk After Curative Liver Resection Oncotarget. Oct, 2017 | Pubmed ID: 29163804 Copy Number Variations of Circulating, Cell-free DNA in Urothelial Carcinoma of the Bladder Patients Treated with Radical Cystectomy: a Prospective Study Oncotarget. Aug, 2017 | Pubmed ID: 28915599 Comparative Study of Whole Genome Amplification and Next Generation Sequencing Performance of Single Cancer Cells Oncotarget. Aug, 2017 | Pubmed ID: 28915574 Biology and Clinical Significance of Circulating Tumor Cell Subpopulations in Lung Cancer Translational Lung Cancer Research. Aug, 2017 | Pubmed ID: 28904887 Tracing the Seeds in the Soil Clinical Chemistry. Nov, 2017 | Pubmed ID: 28687635 Prognostic Impact of Circulating Tumor Cells for Breast Cancer Patients Treated in the Neoadjuvant "Geparquattro" Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2017 | Pubmed ID: 28679772 Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer Clinical Chemistry. Aug, 2017 | Pubmed ID: 28588120 Plasma MicroRNA Signature is Associated with Risk Stratification in Prostate Cancer Patients International Journal of Cancer. 09, 2017 | Pubmed ID: 28571116 Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28560676 Clinical Relevance of Serum HER2 and Circulating Tumor Cell Detection in Metastatic Breast Cancer Patients Anticancer Research. 06, 2017 | Pubmed ID: 28551653 Cancer Stem Cells: The Root of Tumor Recurrence and Metastases Seminars in Cancer Biology. 06, 2017 | Pubmed ID: 28257956 Catch and Release: Rare Cell Analysis from a Functionalised Medical Wire Scientific Reports. Feb, 2017 | Pubmed ID: 28233867 Liquid Biopsies, What We Do Not Know (Yet) Cancer Cell. Feb, 2017 | Pubmed ID: 28196593 Prevalence of Circulating Tumor Cells After Adjuvant Chemotherapy With or Without Anthracyclines in Patients With HER2-negative, Hormone Receptor-positive Early Breast Cancer Clinical Breast Cancer. Jul, 2017 | Pubmed ID: 28190761 Detection and Oncological Effect of Circulating Tumour Cells in Patients with Variant Urothelial Carcinoma Histology Treated with Radical Cystectomy BJU International. 06, 2017 | Pubmed ID: 28182321 Epithelial-mesenchymal Plasticity in Circulating Tumor Cells Journal of Molecular Medicine (Berlin, Germany). Feb, 2017 | Pubmed ID: 28013389 PTEN Mediates the Cross Talk Between Breast and Glial Cells in Brain Metastases Leading to Rapid Disease Progression Oncotarget. Jan, 2017 | Pubmed ID: 28008153 Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2017 | Pubmed ID: 27856601 A Nonrandomized, Prospective, Clinical Study on the Impact of Circulating Tumor Cells on Outcomes of Urothelial Carcinoma of the Bladder Patients Treated with Radical Cystectomy with or Without Adjuvant Chemotherapy International Journal of Cancer. Jan, 2017 | Pubmed ID: 27668704 Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection PLoS Medicine. Dec, 2016 | Pubmed ID: 28027295 Improved Detection of Circulating Tumor Cells in Non-metastatic High-risk Prostate Cancer Patients Scientific Reports. Dec, 2016 | Pubmed ID: 28000772 Liquid Biopsies for Surveillance and Monitoring Treatment Response of Bladder Cancer Annals of Translational Medicine. Oct, 2016 | Pubmed ID: 27826581 Circulating Cell-Free MiR-373, MiR-200a, MiR-200b and MiR-200c in Patients with Epithelial Ovarian Cancer Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27753009 Cancer: A Shocking Protein Complex Nature. 10, 2016 | Pubmed ID: 27706139 Impact of Apoptotic Circulating Tumor Cells (aCTC) in Metastatic Breast Cancer Breast Cancer Research and Treatment. 11, 2016 | Pubmed ID: 27696083 Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells Clinical Chemistry. Nov, 2016 | Pubmed ID: 27630154 Frequent Detection of PIK3CA Mutations in Single Circulating Tumor Cells of Patients Suffering from HER2-negative Metastatic Breast Cancer Molecular Oncology. 10, 2016 | Pubmed ID: 27491860 Chronic UVB-irradiation Actuates Perpetuated Dermal Matrix Remodeling in Female Mice: Protective Role of Estrogen Scientific Reports. 07, 2016 | Pubmed ID: 27460287 TP53 Mutations on Circulating Cell-free DNA EBioMedicine. Aug, 2016 | Pubmed ID: 27412263 Liquid Biopsy-based Clinical Research in Early Breast Cancer: The EORTC 90091-10093 Treat CTC Trial European Journal of Cancer (Oxford, England : 1990). 08, 2016 | Pubmed ID: 27289552 Circulating Tumor DNA As a Cancer Biomarker: Fact or Fiction? Clinical Chemistry. Aug, 2016 | Pubmed ID: 27259816 Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest® PloS One. 2016 | Pubmed ID: 27182774 Heterogeneous PSMA Expression on Circulating Tumor Cells: a Potential Basis for Stratification and Monitoring of PSMA-directed Therapies in Prostate Cancer Oncotarget. Jun, 2016 | Pubmed ID: 27145459 Perspectives on Sipuleucel-T: Its Role in the Prostate Cancer Treatment Paradigm Oncoimmunology. Apr, 2016 | Pubmed ID: 27141392 Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA As Liquid Biopsy Cancer Discovery. 05, 2016 | Pubmed ID: 26969689 Diagnostic and Prognostic Relevance of Circulating Exosomal MiR-373, MiR-200a, MiR-200b and MiR-200c in Patients with Epithelial Ovarian Cancer Oncotarget. Mar, 2016 | Pubmed ID: 26943577 Genetic Traits for Hematogeneous Tumor Cell Dissemination in Cancer Patients Cancer Metastasis Reviews. Mar, 2016 | Pubmed ID: 26931653 Liquid Biopsy: Potential and Challenges Molecular Oncology. Mar, 2016 | Pubmed ID: 26875532 RHAMM Splice Variants Confer Radiosensitivity in Human Breast Cancer Cell Lines Oncotarget. Apr, 2016 | Pubmed ID: 26870892 Functional Studies on Circulating and Disseminated Tumor Cells in Carcinoma Patients Molecular Oncology. Mar, 2016 | Pubmed ID: 26847851 Potential of Circulating Tumor Cells As Blood-based Biomarkers in Cancer Liquid Biopsy Pharmacogenomics. Feb, 2016 | Pubmed ID: 26799583 Limited Prognostic Value of Preoperative Circulating Tumor Cells for Early Biochemical Recurrence in Patients with Localized Prostate Cancer Urologic Oncology. May, 2016 | Pubmed ID: 26795608 Breast Cancer Brain Metastases: Biology and New Clinical Perspectives Breast Cancer Research : BCR. Jan, 2016 | Pubmed ID: 26781299 Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas Clinical Chemistry. Feb, 2016 | Pubmed ID: 26721293 Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2016 | Pubmed ID: 26667488 Diverse Expression Patterns of the EMT Suppressor Grainyhead-like 2 (GRHL2) in Normal and Tumour Tissues International Journal of Cancer. Feb, 2016 | Pubmed ID: 26355710 Evaluation of the Germline Single Nucleotide Polymorphism Rs583522 in the TNFAIP3 Gene As a Prognostic Marker in Esophageal Cancer Cancer Genetics. Dec, 2015 | Pubmed ID: 26598072 Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients Through Sustained Activation of the Unfolded Protein Response Cancer Research. Dec, 2015 | Pubmed ID: 26573792 Iroquois Homeobox 2 Suppresses Cellular Motility and Chemokine Expression in Breast Cancer Cells BMC Cancer. Nov, 2015 | Pubmed ID: 26560478 Tumor-Educated Platelets As Liquid Biopsy in Cancer Patients Cancer Cell. Nov, 2015 | Pubmed ID: 26555171 Tumour Exosome Integrins Determine Organotropic Metastasis Nature. Nov, 2015 | Pubmed ID: 26524530 Heterogeneity of MiR-10b Expression in Circulating Tumor Cells Scientific Reports. Nov, 2015 | Pubmed ID: 26522916 A Versatile Microarray Platform for Capturing Rare Cells Scientific Reports. Oct, 2015 | Pubmed ID: 26493176 Circulating DNA As Biomarker in Breast Cancer Breast Cancer Research : BCR. Oct, 2015 | Pubmed ID: 26453190 Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer Frontiers in Oncology. 2015 | Pubmed ID: 26442219 Data Normalization Strategies for MicroRNA Quantification Clinical Chemistry. Nov, 2015 | Pubmed ID: 26408530 Diagnostic and Prognostic Potential of Serum MiR-7, MiR-16, MiR-25, MiR-93, MiR-182, MiR-376a and MiR-429 in Ovarian Cancer Patients British Journal of Cancer. Nov, 2015 | Pubmed ID: 26393886 Whole Genome Amplification in Genomic Analysis of Single Circulating Tumor Cells Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26374320 Stromal Expression of ALDH1 in Human Breast Carcinomas Indicates Reduced Tumor Progression Oncotarget. Sep, 2015 | Pubmed ID: 26305673 Aberrant Plasma Levels of Circulating MiR-16, MiR-107, MiR-130a and MiR-146a Are Associated with Lymph Node Metastasis and Receptor Status of Breast Cancer Patients Oncotarget. May, 2015 | Pubmed ID: 26033453 Do Circulating Tumor Cells Have a Role in Deciding on Adjuvant Chemotherapy After Radical Cystectomy? Current Urology Reports. Jul, 2015 | Pubmed ID: 26025496 The Impact of HER2 Phenotype of Circulating Tumor Cells in Metastatic Breast Cancer: a Retrospective Study in 107 Patients BMC Cancer. May, 2015 | Pubmed ID: 25972110 Epithelial-mesenchymal Plasticity is a Decisive Feature for the Metastatic Outgrowth of Disseminated WAP-T Mouse Mammary Carcinoma Cells BMC Cancer. Mar, 2015 | Pubmed ID: 25886487 Cyclooxygenase-2 Blockade Can Improve Efficacy of VEGF-targeting Drugs Oncotarget. Mar, 2015 | Pubmed ID: 25849942 Suppression of Early Hematogenous Dissemination of Human Breast Cancer Cells to Bone Marrow by Retinoic Acid-induced 2 Cancer Discovery. May, 2015 | Pubmed ID: 25716347 Establishment and Characterization of a Cell Line from Human Circulating Colon Cancer Cells Cancer Research. Mar, 2015 | Pubmed ID: 25592149 Biology, Detection, and Clinical Implications of Circulating Tumor Cells EMBO Molecular Medicine. Jan, 2015 | Pubmed ID: 25398926 Identification of HERC5 and Its Potential Role in NSCLC Progression International Journal of Cancer. May, 2015 | Pubmed ID: 25353388 Mutant P53 Promotes Epithelial-mesenchymal Plasticity and Enhances Metastasis in Mammary Carcinomas of WAP-T Mice International Journal of Cancer. Mar, 2015 | Pubmed ID: 25195563 Differential Regulation of MAGE-A1 Promoter Activity by BORIS and Sp1, Both Interacting with the TATA Binding Protein BMC Cancer. Nov, 2014 | Pubmed ID: 25363021 An A/C Germline Single-nucleotide Polymorphism in the TNFAIP3 Gene is Associated with Advanced Disease Stage and Survival in Only Surgically Treated Esophageal Cancer Journal of Human Genetics. Dec, 2014 | Pubmed ID: 25354935 Increased Serum Levels of Circulating Exosomal MicroRNA-373 in Receptor-negative Breast Cancer Patients Oncotarget. Oct, 2014 | Pubmed ID: 25333260 PGC-1α Mediates Mitochondrial Biogenesis and Oxidative Phosphorylation in Cancer Cells to Promote metastasis Nature Cell Biology. Oct, 2014 | Pubmed ID: 25241037 The Dynamic Range of Circulating Tumor DNA in Metastatic Breast Cancer Breast Cancer Research : BCR. Aug, 2014 | Pubmed ID: 25107527 Changes in Serum Levels of MiR-21, MiR-210, and MiR-373 in HER2-positive Breast Cancer Patients Undergoing Neoadjuvant Therapy: a Translational Research Project Within the Geparquinto Trial Breast Cancer Research and Treatment. Aug, 2014 | Pubmed ID: 25086636 Hematogenous Dissemination of Glioblastoma Multiforme Science Translational Medicine. Jul, 2014 | Pubmed ID: 25080476 Serial Enumeration of Circulating Tumor Cells Predicts Treatment Response and Prognosis in Metastatic Breast Cancer: a Prospective Study in 393 Patients BMC Cancer. Jul, 2014 | Pubmed ID: 25015676 Loss of CADM1 Expression is Associated with Poor Prognosis and Brain Metastasis in Breast Cancer Patients Oncotarget. May, 2014 | Pubmed ID: 24833255 Circulating Tumor Cells Predict Survival in Early Average-to-high Risk Breast Cancer Patients Journal of the National Cancer Institute. May, 2014 | Pubmed ID: 24832787 Squamous Cell Carcinoma of the Oral Cavity and Circulating Tumour Cells World Journal of Clinical Oncology. May, 2014 | Pubmed ID: 24829858 Prognostic Impact of Perineural, Blood and Lymph Vessel Invasion for Esophageal Cancer Histology and Histopathology. Nov, 2014 | Pubmed ID: 24819775 Tumor Signatures in the Blood Nature Biotechnology. May, 2014 | Pubmed ID: 24811515 International Study on Inter-reader Variability for Circulating Tumor Cells in Breast Cancer Breast Cancer Research : BCR. Apr, 2014 | Pubmed ID: 24758318 Clinical Validity of Circulating Tumour Cells in Patients with Metastatic Breast Cancer: a Pooled Analysis of Individual Patient Data The Lancet. Oncology. Apr, 2014 | Pubmed ID: 24636208 AKT3 Regulates ErbB2, ErbB3 and Estrogen Receptor α Expression and Contributes to Endocrine Therapy Resistance of ErbB2(+) Breast Tumor Cells from Balb-neuT Mice Cellular Signalling. May, 2014 | Pubmed ID: 24463007 Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of Patients with Squamous Cell Carcinoma of the Oral Cavity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2014 | Pubmed ID: 24218516 EGFR Intron-1 CA Repeat Polymorphism is a Predictor of Relapse and Survival in Complete Resected Only Surgically Treated Esophageal Cancer Targeted Oncology. Mar, 2014 | Pubmed ID: 23377570 Real-time Liquid Biopsy: Circulating Tumor Cells Versus Circulating Tumor DNA Annals of Translational Medicine. Jul, 2013 | Pubmed ID: 25332962 Advances in Circulating Tumor Cells (ACTC): from Basic Research to Clinical Practice Breast Cancer Research : BCR. Dec, 2013 | Pubmed ID: 24314311 Real-time Liquid Biopsy in Cancer Patients: Fact or Fiction? Cancer Research. Nov, 2013 | Pubmed ID: 24145355 Tumor-Induced Osteoclast MiRNA Changes As Regulators and Biomarkers of Osteolytic Bone Metastasis Cancer Cell. Oct, 2013 | Pubmed ID: 24135284 CXCR7 Expression in Esophageal Cancer Journal of Translational Medicine. Sep, 2013 | Pubmed ID: 24074251 Heterogeneity of Estrogen Receptor Expression in Circulating Tumor Cells from Metastatic Breast Cancer Patients PloS One. 2013 | Pubmed ID: 24058649 Axl, a Prognostic and Therapeutic Target in Acute Myeloid Leukemia Mediates Paracrine Crosstalk of Leukemia Cells with Bone Marrow Stroma Blood. Oct, 2013 | Pubmed ID: 23982172 Functional Activity of RLIM/Rnf12 is Regulated by Phosphorylation-dependent Nucleocytoplasmic Shuttling Molecular Biology of the Cell. Oct, 2013 | Pubmed ID: 23904271 Dual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer The Journal of Biological Chemistry. Aug, 2013 | Pubmed ID: 23814079 Tracking Tumor Resistance Using 'liquid Biopsies' Nature Medicine. Jun, 2013 | Pubmed ID: 23744147 Frequent Genetic Alterations in EGFR- and HER2-driven Pathways in Breast Cancer Brain Metastases The American Journal of Pathology. Jul, 2013 | Pubmed ID: 23665199 Presence of EpCAM-positive Circulating Tumor Cells As Biomarker for Systemic Disease Strongly Correlates to Survival in Patients with Hepatocellular Carcinoma International Journal of Cancer. Nov, 2013 | Pubmed ID: 23616258 Tumor-associated Copy Number Changes in the Circulation of Patients with Prostate Cancer Identified Through Whole-genome Sequencing Genome Medicine. 2013 | Pubmed ID: 23561577 Genomic Deletion of MAP3K7 at 6q12-22 is Associated with Early PSA Recurrence in Prostate Cancer and Absence of TMPRSS2:ERG Fusions Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jul, 2013 | Pubmed ID: 23370768 Circulating Tumor Cells As Therapy-related Biomarkers in Cancer Patients Cancer Immunology, Immunotherapy : CII. May, 2013 | Pubmed ID: 23314304 Biologic Challenges in the Detection of Circulating Tumor Cells Cancer Research. Jan, 2013 | Pubmed ID: 23271724 Frequent Intratumoral Heterogeneity of EGFR Gene Copy Gain in Non-small Cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Mar, 2013 | Pubmed ID: 23238037 Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation Cancer Research. Jan, 2013 | Pubmed ID: 23149920 Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer Clinical Chemistry. Jan, 2013 | Pubmed ID: 23136247 Low-grade and High-grade Mammary Carcinomas in WAP-T Transgenic Mice Are Independent Entities Distinguished by Met Expression International Journal of Cancer. Mar, 2013 | Pubmed ID: 22907219 Clinical Relevance of Loss of 11p15 in Primary and Metastatic Breast Cancer: Association with Loss of PRKCDBP Expression in Brain Metastases PloS One. 2012 | Pubmed ID: 23118876 Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-positive Esophageal Cancer PloS One. 2012 | Pubmed ID: 23082154 Circulating Tumor-derived Biomarkers in Lung Cancer Journal of Thoracic Disease. Oct, 2012 | Pubmed ID: 23050103 Loss of Heterozygosity at Tumor Suppressor Genes Detectable on Fractionated Circulating Cell-free Tumor DNA As Indicator of Breast Cancer Progression Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2012 | Pubmed ID: 23014523 Prognostic Impact of Circulating Tumor Cells Assessed with the CellSearch System™ and AdnaTest Breast™ in Metastatic Breast Cancer Patients: the DETECT Study Breast Cancer Research : BCR. Aug, 2012 | Pubmed ID: 22894854 Considerations in the Development of Circulating Tumor Cell Technology for Clinical Use Journal of Translational Medicine. 2012 | Pubmed ID: 22747748 Low Levels of Cell-free Circulating MiR-361-3p and MiR-625* As Blood-based Markers for Discriminating Malignant from Benign Lung Tumors PloS One. 2012 | Pubmed ID: 22675530 Disseminated Tumor Cells in Bone Marrow and the Natural Course of Resected Esophageal Cancer Annals of Surgery. Jun, 2012 | Pubmed ID: 22580852 Relevance of PTEN Loss in Brain Metastasis Formation in Breast Cancer Patients Breast Cancer Research : BCR. Mar, 2012 | Pubmed ID: 22429330 The Current Role of Circulating Tumor Cells in the Diagnosis and Management of Bone Metastases in Advanced Prostate Cancer Future Oncology (London, England). Mar, 2012 | Pubmed ID: 22409467 Opposite Roles of FOXA1 and NKX2-1 in Lung Cancer Progression Genes, Chromosomes & Cancer. Jun, 2012 | Pubmed ID: 22383183 Diagnostic Potential of PTEN-targeting MiR-214 in the Blood of Breast Cancer Patients Breast Cancer Research and Treatment. Aug, 2012 | Pubmed ID: 22350790 Changes in Keratin Expression During Metastatic Progression of Breast Cancer: Impact on the Detection of Circulating Tumor Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2012 | Pubmed ID: 22228641 Circulating Epithelial Cells in Patients with Benign Colon Diseases Clinical Chemistry. May, 2012 | Pubmed ID: 22205690 Disseminated Tumor Cells in Pancreatic Cancer-an Independent Prognosticator of Disease Progression and Survival International Journal of Cancer. Aug, 2012 | Pubmed ID: 21932421 ALCAM (CD166) Expression and Serum Levels Are Markers for Poor Survival of Esophageal Cancer Patients International Journal of Cancer. Jul, 2012 | Pubmed ID: 21858815 The Interrelating Dynamics of Hypoxic Tumor Microenvironments and Cancer Cell Phenotypes in Cancer Metastasis Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. Apr, 2012 | Pubmed ID: 21626313 Circulating Tumors Cells As Biomarkers: Progress Toward Biomarker Qualification Cancer Journal (Sudbury, Mass.). Nov-Dec, 2011 | Pubmed ID: 22157288 Quantitative High-resolution Genomic Analysis of Single Cancer Cells PloS One. 2011 | Pubmed ID: 22140428 VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-positive Osteoclast Progenitors Cancer Cell. Dec, 2011 | Pubmed ID: 22137794 ERG Status is Unrelated to PSA Recurrence in Radically Operated Prostate Cancer in the Absence of Antihormonal Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011 | Pubmed ID: 21791629 Evaluation of Cell-free Tumour DNA and RNA in Patients with Breast Cancer and Benign Breast Disease Molecular BioSystems. Oct, 2011 | Pubmed ID: 21785770 Distinct Functional Roles of Akt Isoforms for Proliferation, Survival, Migration and EGF-mediated Signalling in Lung Cancer Derived Disseminated Tumor Cells Cellular Signalling. Dec, 2011 | Pubmed ID: 21777670 Controversies in Clinical Cancer Dormancy Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746894 Prospective Evaluation of Serum Tissue Inhibitor of Metalloproteinase 1 and Carbonic Anhydrase IX in Correlation to Circulating Tumor Cells in Patients with Metastatic Breast Cancer Breast Cancer Research : BCR. Jul, 2011 | Pubmed ID: 21745383 Cell-free Nucleic Acids As Biomarkers in Cancer Patients Nature Reviews. Cancer. Jun, 2011 | Pubmed ID: 21562580 Screening for Circulating Nucleic Acids and Caspase Activity in the Peripheral Blood As Potential Diagnostic Tools in Lung Cancer Molecular Oncology. Jun, 2011 | Pubmed ID: 21398193 The GNAS1 T393C Single Nucleotide Polymorphism Predicts the Natural Postoperative Course of Complete Resected Esophageal Cancer Cellular Oncology (Dordrecht). Aug, 2011 | Pubmed ID: 21340746 Apoptosis-related Deregulation of Proteolytic Activities and High Serum Levels of Circulating Nucleosomes and DNA in Blood Correlate with Breast Cancer Progression BMC Cancer. Jan, 2011 | Pubmed ID: 21211028 Biologic Role of Activated Leukocyte Cell Adhesion Molecule Overexpression in Breast Cancer Cell Lines and Clinical Tumor Tissue Breast Cancer Research and Treatment. Sep, 2011 | Pubmed ID: 20972617 Genomic Profiling of Cell-free DNA in Blood and Bone Marrow of Prostate Cancer Patients Journal of Cancer Research and Clinical Oncology. May, 2011 | Pubmed ID: 20683729 Detection and Clinical Relevance of Early Disseminated Breast Cancer Cells Depend on Their Cytokeratin Expression Pattern Breast Cancer Research and Treatment. Feb, 2011 | Pubmed ID: 20449649 Prospective Multi-centre Study to Validate Chromogenic in Situ Hybridisation for the Assessment of HER2 Gene Amplification in Specimens from Adjuvant and Metastatic Breast Cancer Patients Journal of Cancer Research and Clinical Oncology. Feb, 2011 | Pubmed ID: 20396915 Circulating MicroRNAs As Blood-based Markers for Patients with Primary and Metastatic Breast Cancer Breast Cancer Research : BCR. 2010 | Pubmed ID: 21047409 Advancing Personalized Cancer Therapy by Detection and Characterization of Circulating Carcinoma Cells Annals of the New York Academy of Sciences. Oct, 2010 | Pubmed ID: 20973800 What's New on Circulating Tumor Cells? A Meeting Report Breast Cancer Research : BCR. 2010 | Pubmed ID: 20727231 BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2010 | Pubmed ID: 20592016 Promoter- and Cell-specific Epigenetic Regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG Binding Proteins and Histone Modifications BMC Cancer. Jun, 2010 | Pubmed ID: 20565761 Discovery of a Novel Unfolded Protein Response Phenotype of Cancer Stem/progenitor Cells from the Bone Marrow of Breast Cancer Patients Journal of Proteome Research. Jun, 2010 | Pubmed ID: 20423148 Detection and HER2 Expression of Circulating Tumor Cells: Prospective Monitoring in Breast Cancer Patients Treated in the Neoadjuvant GeparQuattro Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2010 | Pubmed ID: 20406831 Insights into Minimal Residual Disease in Cancer Patients: Implications for Anti-cancer Therapies European Journal of Cancer (Oxford, England : 1990). May, 2010 | Pubmed ID: 20347588 Molecular Analysis of the Polymorphisms of Thymidylate Synthase on Cell-free Circulating DNA in Blood of Patients with Advanced Colorectal Carcinoma International Journal of Cancer. Aug, 2010 | Pubmed ID: 19998340 Clinical Relevance and Current Challenges of Research on Disseminating Tumor Cells in Cancer Patients Breast Cancer Research : BCR. 2009 | Pubmed ID: 20030861 Comparative Evaluation of Cell-free Tumor DNA in Blood and Disseminated Tumor Cells in Bone Marrow of Patients with Primary Breast Cancer Breast Cancer Research : BCR. 2009 | Pubmed ID: 19772563 Two-dimensional Differential Gel Electrophoresis of a Cell Line Derived from a Breast Cancer Micrometastasis Revealed a Stem/ Progenitor Cell Protein Profile Journal of Proteome Research. Apr, 2009 | Pubmed ID: 19714817 Full-length Cytokeratin-19 is Released by Human Tumor Cells: a Potential Role in Metastatic Progression of Breast Cancer Breast Cancer Research : BCR. 2009 | Pubmed ID: 19549321 Cancer Micrometastases Nature Reviews. Clinical Oncology. Jun, 2009 | Pubmed ID: 19399023 Pathology: Are Circulating Tumor Cells Predictive of Overall Survival? Nature Reviews. Clinical Oncology. 04, 2009 | Pubmed ID: 19333222 Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19208797 Cell-free Tumor DNA in Blood Plasma As a Marker for Circulating Tumor Cells in Prostate Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2009 | Pubmed ID: 19188176 Regulation of Estrogen-dependent Transcription by the LIM Cofactors CLIM and RLIM in Breast Cancer Cancer Research. Jan, 2009 | Pubmed ID: 19117995 HER2 As Marker for the Detection of Circulating Tumor Cells Breast Cancer Research and Treatment. Oct, 2009 | Pubmed ID: 19115105 Micrometastatic Spread in Breast Cancer: Detection, Molecular Characterization and Clinical Relevance Breast Cancer Research : BCR. 2008 | Pubmed ID: 19091005 Detection and Monitoring of Cell-free DNA in Blood of Patients with Colorectal Cancer Annals of the New York Academy of Sciences. Aug, 2008 | Pubmed ID: 18837946 Cancer Micrometastasis and Tumour Dormancy APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2008 | Pubmed ID: 18834417 Prognostic Significance of Disseminated Tumor Cells in the Bone Marrow of Prostate Cancer Patients Treated with Neoadjuvant Hormone Treatment Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2008 | Pubmed ID: 18794550 Review: Biological Relevance of Disseminated Tumor Cells in Cancer Patients International Journal of Cancer. Nov, 2008 | Pubmed ID: 18712708 Disseminated Tumor Cells in Bone Marrow and Circulating Tumor Cells in Blood of Breast Cancer Patients: Current State of Detection and Characterization Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 2008 | Pubmed ID: 18544969 Detection, Clinical Relevance and Specific Biological Properties of Disseminating Tumour Cells Nature Reviews. Cancer. May, 2008 | Pubmed ID: 18404148 Identification of Loss of Heterozygosity on Circulating Free DNA in Peripheral Blood of Prostate Cancer Patients: Potential and Technical Improvements Clinical Chemistry. Apr, 2008 | Pubmed ID: 18281424 A Critical Evaluation of Loss of Heterozygosity Detected in Tumor Tissues, Blood Serum and Bone Marrow Plasma from Patients with Breast Cancer Breast Cancer Research : BCR. 2007 | Pubmed ID: 17915011 L1 is Associated with Micrometastatic Spread and Poor Outcome in Colorectal Cancer Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Nov, 2007 | Pubmed ID: 17873897 Microsatellite Analysis in Serum DNA As a Diagnostic Tool for Distinction of Patients with Unknown Pancreatic Masses Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Sep, 2007 | Pubmed ID: 17721326 Short Tandem Repeat Polymorphism in Exon 4 of Esophageal Cancer-related Gene 2 Detected in Genomic DNA is a Prognostic Marker for Esophageal Cancer American Journal of Surgery. Sep, 2007 | Pubmed ID: 17693286 Methyl-CpG Binding Domain Proteins and Their Involvement in the Regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 Gene Promoters Molecular Cancer Research : MCR. Jul, 2007 | Pubmed ID: 17634428 Central Mesenteric Lymph Node BER-Ep4+ Cells in Colorectal Cancer: Challenge to Sentinel Node Concept? Digestive Surgery. 2007 | Pubmed ID: 17369677 Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: a Validation Study of the CellSearch System Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2007 | Pubmed ID: 17289886 Detection of Tumor-specific DNA in Blood and Bone Marrow Plasma from Patients with Prostate Cancer International Journal of Cancer. Apr, 2007 | Pubmed ID: 17205532 Comparison of Genetic Alterations Detected in Circulating Microsatellite DNA in Blood Plasma Samples of Patients with Prostate Cancer and Benign Prostatic Hyperplasia Annals of the New York Academy of Sciences. Sep, 2006 | Pubmed ID: 17108215 Recent Translational Research: Circulating Tumor Cells in Breast Cancer Patients Breast Cancer Research : BCR. 2006 | Pubmed ID: 16953898 Lymphatic Spread and Microinvolvement in Adenocarcinoma of the Esophago-gastric Junction Journal of Surgical Oncology. Sep, 2006 | Pubmed ID: 16917878 High Incidence of EMMPRIN Expression in Human Tumors International Journal of Cancer. Oct, 2006 | Pubmed ID: 16721788 Promoter Demethylation and Histone Acetylation Mediate Gene Expression of MAGE-A1, -A2, -A3, and -A12 in Human Cancer Cells Molecular Cancer Research : MCR. May, 2006 | Pubmed ID: 16687489 Prognostic and Predictive Impact of Soluble Epidermal Growth Factor Receptor (sEGFR) Protein in the Serum of Patients Treated with Chemotherapy for Metastatic Breast Cancer Anticancer Research. Mar-Apr, 2006 | Pubmed ID: 16619561 Changes in Cytoskeletal Protein Composition Indicative of an Epithelial-mesenchymal Transition in Human Micrometastatic and Primary Breast Carcinoma Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2005 | Pubmed ID: 16299229 Circulating Tumor Cells in Breast Cancer: Correlation to Bone Marrow Micrometastases, Heterogeneous Response to Systemic Therapy and Low Proliferative Activity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2005 | Pubmed ID: 15897564 Influence of Immunomagnetic Enrichment on Gene Expression of Tumor Cells Journal of Translational Medicine. Mar, 2005 | Pubmed ID: 15771776 Bone Marrow Micrometastases and Circulating Tumor Cells: Current Aspects and Future Perspectives Breast Cancer Research : BCR. 2004 | Pubmed ID: 15535856 Dissecting the Metastatic Cascade Nature Reviews. Cancer. Jun, 2004 | Pubmed ID: 15170447 Amplificação de genoma pré-enriquecimento e toda célula alvo para jusante caracterização única célula Shukun Chen*1, Amin El-Heliebi*1, Julia Schmid1, Karl Kashofer2, Zbigniew T. Czyż3, Bernhard Michael Polzer3, Klaus Pantel4, Thomas Kroneis1,5, Peter Sedlmayr1 1Institute of Cell Biology, Histology and Embryology, Medical University of Graz, 2Institute of Pathology, Medical University of Graz, 3Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, 4Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, 5Sahlgrenska Cancer Center, University of Gothenburg JoVE 56394 Cancer Research
Amplificação de genoma pré-enriquecimento e toda célula alvo para jusante caracterização única célula Shukun Chen*1, Amin El-Heliebi*1, Julia Schmid1, Karl Kashofer2, Zbigniew T. Czyż3, Bernhard Michael Polzer3, Klaus Pantel4, Thomas Kroneis1,5, Peter Sedlmayr1 1Institute of Cell Biology, Histology and Embryology, Medical University of Graz, 2Institute of Pathology, Medical University of Graz, 3Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, 4Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, 5Sahlgrenska Cancer Center, University of Gothenburg JoVE 56394 Cancer Research
