Kullervo Hynynen Physical Sciences Platform Sunnybrook Research Institute Biography Publications Institution JoVE Articles Kullervo Hynynen has not added a biography. If you are Kullervo Hynynen and would like to personalize this page please email our Author Liaison for assistance. Publications Targeted Nanoparticle for Co-delivery of HER2 SiRNA and a Taxane to Mirror the Standard Treatment of HER2+ Breast Cancer: Efficacy in Breast Tumor and Brain Metastasis Small (Weinheim an Der Bergstrasse, Germany). Jan, 2022 | Pubmed ID: 35083840 Ultrasound Delivery of a TrkA Agonist Confers Neuroprotection to Alzheimer-associated Pathologies Brain : a Journal of Neurology. Dec, 2021 | Pubmed ID: 34919633 Transgene Distribution and Immune Response After Ultrasound Delivery of RAAV9 and PHP.B to the Brain in a Mouse Model of Amyloidosis Molecular Therapy. Methods & Clinical Development. Dec, 2021 | Pubmed ID: 34761053 MR-guided Focused Ultrasound Enhances Delivery of Trastuzumab to Her2-positive Brain Metastases Science Translational Medicine. 10, 2021 | Pubmed ID: 34644145 Comparison of Computer Simulations and Clinical Treatment Results of Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids Medical Physics. Oct, 2021 | Pubmed ID: 34601729 Sub-millimetre Precision of Drug Delivery in the Brain from Ultrasound-triggered Nanodroplets Journal of Controlled Release : Official Journal of the Controlled Release Society. 10, 2021 | Pubmed ID: 34530050 Focused Ultrasound Neuromodulation International Review of Neurobiology. 2021 | Pubmed ID: 34446247 Intravenous and Non-invasive Drug Delivery to the Mouse Basal ForebrainUsing MRI-guided Focused Ultrasound Bio-protocol. Jun, 2021 | Pubmed ID: 34262999 The Mechanical Potential of Ultrasound on Nervous Tissue The Journal of the Acoustical Society of America. 06, 2021 | Pubmed ID: 34241452 Erratum: "Registration of Human Skull Computed Tomography Data to an Ultrasound Treatment Space Using a Sparse High Frequency Ultrasound Hemispherical Array" [Med. Phys. 43, 5063-5071 (2016)] Medical Physics. Jun, 2021 | Pubmed ID: 34235769 Corrigendum: Perfusion Fixation Methods for Preclinical Biodistribution Studies: a Comparative Assessment Using Automated Image Processing (2021 017001) Methods and Applications in Fluorescence. Jun, 2021 | Pubmed ID: 34110305 Therapeutic Agent Delivery Across the Blood-Brain Barrier Using Focused Ultrasound Annual Review of Biomedical Engineering. 07, 2021 | Pubmed ID: 33752471 MR-guided Focused Ultrasound Liquid Biopsy Enriches Circulating Biomarkers in Patients with Brain Tumors Neuro-oncology. 10, 2021 | Pubmed ID: 33693781 Ultrasound-sensitive Nanodroplets Achieve Targeted Neuromodulation Journal of Controlled Release : Official Journal of the Controlled Release Society. 04, 2021 | Pubmed ID: 33600879 Systemic AAV6-synapsin-GFP Administration Results in Lower Liver Biodistribution, Compared to AAV1&2 and AAV9, with Neuronal Expression Following Ultrasound-mediated Brain Delivery Scientific Reports. 01, 2021 | Pubmed ID: 33479314 Novel Treatment Approaches for Brain Tumour from a Blood-Brain Barrier Perspective Handbook of Experimental Pharmacology. Jan, 2021 | Pubmed ID: 33454856 Neutrophil Recruitment and Leukocyte Response Following Focused Ultrasound and Microbubble Mediated Blood-brain Barrier Treatments Theranostics. 2021 | Pubmed ID: 33408773 Vasculotide Restores the Blood-brain Barrier After Focused Ultrasound-induced Permeability in a Mouse Model of Alzheimer's Disease International Journal of Medical Sciences. 2021 | Pubmed ID: 33390817 Perfusion Fixation Methods for Preclinical Biodistribution Studies: A Comparative Assessment Using Automated Image Processing Methods and Applications in Fluorescence. Jan, 2021 | Pubmed ID: 33316782 Technical Principles and Clinical Workflow of Transcranial MR-Guided Focused Ultrasound Stereotactic and Functional Neurosurgery. 2021 | Pubmed ID: 33302282 MRI-guided Focused Ultrasound Enhances Drug Delivery in Experimental Diffuse Intrinsic Pontine Glioma Journal of Controlled Release : Official Journal of the Controlled Release Society. 02, 2021 | Pubmed ID: 33188825 Applications of Focused Ultrasound in the Brain: from Thermoablation to Drug Delivery Nature Reviews. Neurology. 01, 2021 | Pubmed ID: 33106619 Comparing Rapid Short-pulse to Tone Burst Sonication Sequences for Focused Ultrasound and Microbubble-mediated Blood-brain Barrier Permeability Enhancement Journal of Controlled Release : Official Journal of the Controlled Release Society. 01, 2021 | Pubmed ID: 33022327 Focused Ultrasound and Microbubbles-Mediated Drug Delivery to Brain Tumor Pharmaceutics. Dec, 2020 | Pubmed ID: 33374205 Microbubble Formulation Influences Inflammatory Response to Focused Ultrasound Exposure in the Brain Scientific Reports. 12, 2020 | Pubmed ID: 33299094 Clinically Approved IVIg Delivered to the Hippocampus with Focused Ultrasound Promotes Neurogenesis in a Model of Alzheimer's Disease Proceedings of the National Academy of Sciences of the United States of America. 12, 2020 | Pubmed ID: 33288687 Systematic Examination of Low-intensity Ultrasound Parameters on Human Motor Cortex Excitability and Behavior ELife. 11, 2020 | Pubmed ID: 33236981 Technical and Radiographic Considerations for Magnetic Resonance Imaging-guided Focused Ultrasound Capsulotomy Journal of Neurosurgery. Sep, 2020 | Pubmed ID: 32977311 Novel Fractionated Ultrashort Thermal Exposures with MRI-guided Focused Ultrasound for Treating Tumors with Thermosensitive Drugs Science Advances. Sep, 2020 | Pubmed ID: 32917589 Echo-Focusing in Transcranial Focused Ultrasound Thalamotomy for Essential Tremor: A Feasibility Study Movement Disorders : Official Journal of the Movement Disorder Society. 12, 2020 | Pubmed ID: 32815611 Ultrafast Three-dimensional Microbubble Imaging Predicts Tissue Damage Volume Distributions During Nonthermal Brain Ablation Theranostics. 2020 | Pubmed ID: 32641988 Magnetic Resonance-guided Focused Ultrasound Capsulotomy for Refractory Obsessive Compulsive Disorder and Major Depressive Disorder: Clinical and Imaging Results from Two Phase I Trials Molecular Psychiatry. 09, 2020 | Pubmed ID: 32404942 Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation Nano Letters. 06, 2020 | Pubmed ID: 32374617 Focused Ultrasound As a Novel Strategy for Noninvasive Gene Delivery to Retinal Müller Glia Theranostics. 2020 | Pubmed ID: 32194850 Localized Anesthesia of a Specific Brain Region Using Ultrasound-responsive Barbiturate Nanodroplets Theranostics. 2020 | Pubmed ID: 32194839 Investigating the Effects of Dexamethasone on Blood-brain Barrier Permeability and Inflammatory Response Following Focused Ultrasound and Microbubble Exposure Theranostics. 2020 | Pubmed ID: 32042325 A Noninvasive Ultrasound Resonance Method for Detecting Skull Induced Phase Shifts May Provide a Signal for Adaptive Focusing IEEE Transactions on Bio-medical Engineering. 09, 2020 | Pubmed ID: 31976875 Super-resolution Ultrasound Imaging Ultrasound in Medicine & Biology. 04, 2020 | Pubmed ID: 31973952 Transcranial Photoacoustic Detection of Blood-Brain Barrier Disruption Following Focused Ultrasound-Mediated Nanoparticle Delivery Molecular Imaging and Biology. 04, 2020 | Pubmed ID: 31286352 Strategy to Enhance Transgene Expression in Proximity of Amyloid Plaques in a Mouse Model of Alzheimer's Disease Theranostics. 2019 | Pubmed ID: 31754385 Tractography-based Targeting of the Ventral Intermediate Nucleus: Accuracy and Clinical Utility in MRgFUS Thalamotomy Journal of Neurosurgery. Sep, 2019 | Pubmed ID: 31561221 First-in-human Trial of Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis Using MR-guided Focused Ultrasound Nature Communications. 09, 2019 | Pubmed ID: 31558719 Glymphatics Visualization After Focused Ultrasound-Induced Blood-Brain Barrier Opening in Humans Annals of Neurology. 12, 2019 | Pubmed ID: 31525269 Safety and Efficacy of Focused Ultrasound Induced Blood-brain Barrier Opening, an Integrative Review of Animal and Human Studies Journal of Controlled Release : Official Journal of the Controlled Release Society. 09, 2019 | Pubmed ID: 31326464 MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model Scientific Reports. 07, 2019 | Pubmed ID: 31320671 Resting State Functional Connectivity Changes After MR-guided Focused Ultrasound Mediated Blood-brain Barrier Opening in Patients with Alzheimer's Disease NeuroImage. 10, 2019 | Pubmed ID: 31254646 Acoustic Radiation Force Induced Accumulation and Dynamics of Microbubbles on Compliant Surfaces Physics in Medicine and Biology. 07, 2019 | Pubmed ID: 31082815 Accumulated Thermal Dose in MRI-guided Focused Ultrasound for Essential Tremor: Repeated Sonications with Low Focal Temperatures Journal of Neurosurgery. May, 2019 | Pubmed ID: 31075781 The Relevance of Skull Density Ratio in Selecting Candidates for Transcranial MR-guided Focused Ultrasound Journal of Neurosurgery. May, 2019 | Pubmed ID: 31051458 MRI-Guided Focused Ultrasound for Targeted Delivery of RAAV to the Brain Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30783974 Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study Scientific Reports. 01, 2019 | Pubmed ID: 30674905 Evaluating the Safety Profile of Focused Ultrasound and Microbubble-mediated Treatments to Increase Blood-brain Barrier Permeability Expert Opinion on Drug Delivery. 02, 2019 | Pubmed ID: 30628455 Advances in Acoustic Monitoring and Control of Focused Ultrasound-mediated Increases in Blood-brain Barrier Permeability The British Journal of Radiology. Apr, 2019 | Pubmed ID: 30507302 Enhancing Checkpoint Inhibitor Therapy with Ultrasound Stimulated Microbubbles Ultrasound in Medicine & Biology. 02, 2019 | Pubmed ID: 30447880 Hyperthermia-induced Drug Delivery in Humans Nature Biomedical Engineering. 09, 2018 | Pubmed ID: 31015680 Receiver Array Design for Sonothrombolysis Treatment Monitoring in Deep Vein Thrombosis Physics in Medicine and Biology. Nov, 2018 | Pubmed ID: 30484436 Focused Ultrasound Thalamotomy Location Determines Clinical Benefits in Patients with Essential Tremor Brain : a Journal of Neurology. 12, 2018 | Pubmed ID: 30452554 Microbubble-assisted MRI-guided Focused Ultrasound for Hyperthermia at Reduced Power Levels International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018 | Pubmed ID: 30295119 Magnetic Resonance-guided Focused Ultrasound Thalamotomy for Treatment of Essential Tremor: A 2-year Outcome Study Movement Disorders : Official Journal of the Movement Disorder Society. 10, 2018 | Pubmed ID: 30288794 Noninvasive Delivery of an α-synuclein Gene Silencing Vector with Magnetic Resonance-guided Focused Ultrasound Movement Disorders : Official Journal of the Movement Disorder Society. 10, 2018 | Pubmed ID: 30264465 Time Course of Focused Ultrasound Effects on β-amyloid Plaque Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease Scientific Reports. 09, 2018 | Pubmed ID: 30232364 Angiogenic Response of Rat Hippocampal Vasculature to Focused Ultrasound-mediated Increases in Blood-brain Barrier Permeability Scientific Reports. 08, 2018 | Pubmed ID: 30111814 Predicting Lesion Size by Accumulated Thermal Dose in MR-guided Focused Ultrasound for Essential Tremor Medical Physics. Oct, 2018 | Pubmed ID: 30098027 Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to The Brain Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30051428 Blood-brain Barrier Opening in Alzheimer's Disease Using MR-guided Focused Ultrasound Nature Communications. 07, 2018 | Pubmed ID: 30046032 Microbubble Localization for Three-Dimensional Superresolution Ultrasound Imaging Using Curve Fitting and Deconvolution Methods IEEE Transactions on Bio-medical Engineering. 12, 2018 | Pubmed ID: 29993387 Preliminary Investigation of Focused Ultrasound-Facilitated Drug Delivery for the Treatment of Leptomeningeal Metastases Scientific Reports. 06, 2018 | Pubmed ID: 29899537 Three-dimensional Transcranial Microbubble Imaging for Guiding Volumetric Ultrasound-mediated Blood-brain Barrier Opening Theranostics. 2018 | Pubmed ID: 29896293 An MR-based Quantitative Intraventricular Hemorrhage Porcine Model for MR-guided Focused Ultrasound Thrombolysis Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. 09, 2018 | Pubmed ID: 29796753 The Reduction in Treatment Efficiency at High Acoustic Powers During MR-guided Transcranial Focused Ultrasound Thalamotomy for Essential Tremor Medical Physics. Jul, 2018 | Pubmed ID: 29758099 Brainstem Blood Brain Barrier Disruption Using Focused Ultrasound: A Demonstration of Feasibility and Enhanced Doxorubicin Delivery Journal of Controlled Release : Official Journal of the Controlled Release Society. 07, 2018 | Pubmed ID: 29753957 Skull Bone Marrow Injury Caused by MR-guided Focused Ultrasound for Cerebral Functional Procedures Journal of Neurosurgery. 05, 2018 | Pubmed ID: 29726769 Reply to Kovacs .: Concerning Acute Inflammatory Response Following Focused Ultrasound and Microbubbles in the Brain Theranostics. 2018 | Pubmed ID: 29722372 Antidepressant Effects of Focused Ultrasound Induced Blood-brain-barrier Opening Behavioural Brain Research. 04, 2018 | Pubmed ID: 29326057 Investigating the Efficacy of a Combination Aβ-targeted Treatment in a Mouse Model of Alzheimer's Disease Brain Research. Jan, 2018 | Pubmed ID: 29066368 Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose Theranostics. 2017 | Pubmed ID: 29109793 Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging Theranostics. 2017 | Pubmed ID: 28912896 Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With Two-Photon Microscopy Theranostics. 2017 | Pubmed ID: 28819458 Megahertz Rate, Volumetric Imaging of Bubble Clouds in Sonothrombolysis Using a Sparse Hemispherical Receiver Array Physics in Medicine and Biology. Sep, 2017 | Pubmed ID: 28786395 A Viscoelastic Model for the Prediction of Transcranial Ultrasound Propagation: Application for the Estimation of Shear Acoustic Properties in the Human Skull Physics in Medicine and Biology. Aug, 2017 | Pubmed ID: 28783716 Design of Patient-specific Focused Ultrasound Arrays for Non-invasive Brain Therapy with Increased Trans-skull Transmission and Steering Range Physics in Medicine and Biology. Aug, 2017 | Pubmed ID: 28665289 Design of a HIFU Array for the Treatment of Deep Venous Thrombosis: a Simulation Study Physics in Medicine and Biology. Jul, 2017 | Pubmed ID: 28486218 A Computerized Tablet System for Evaluating Treatment of Essential Tremor by Magnetic Resonance Guided Focused Ultrasound BMC Neurology. Apr, 2017 | Pubmed ID: 28412948 Focused Ultrasound As a Novel Strategy for Alzheimer Disease Therapeutics Annals of Neurology. 05, 2017 | Pubmed ID: 28395123 Acute Effects of Focused Ultrasound-induced Increases in Blood-brain Barrier Permeability on Rat Microvascular Transcriptome Scientific Reports. 04, 2017 | Pubmed ID: 28374753 Urinary Cytokines/chemokines After Magnetic Resonance-guided High Intensity Focused Ultrasound for Palliative Treatment of Painful Bone Metastases Annals of Palliative Medicine. Jan, 2017 | Pubmed ID: 28209068 To Heat or Not to Heat: Challenges with Clinical Translation of Thermosensitive Liposomes Journal of Controlled Release : Official Journal of the Controlled Release Society. 03, 2017 | Pubmed ID: 28122204 Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening Volume Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Mar, 2017 | Pubmed ID: 28108988 Magnetic Resonance-Guided High-Intensity-Focused Ultrasound for Palliation of Painful Skeletal Metastases: A Pilot Study Technology in Cancer Research & Treatment. Oct, 2017 | Pubmed ID: 27480322 Opening the Blood-Brain Barrier with MR Imaging-guided Focused Ultrasound: Preclinical Testing on a Trans-Human Skull Porcine Model Radiology. Jan, 2017 | Pubmed ID: 27420647 Noninvasive and Targeted Delivery of Therapeutics to the Brain Using Focused Ultrasound Neuropharmacology. Jul, 2017 | Pubmed ID: 26907805 A Tikhonov Regularization Scheme for Focus Rotations With Focused Ultrasound-Phased Arrays IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 12, 2016 | Pubmed ID: 27913323 A Multi-frequency Sparse Hemispherical Ultrasound Phased Array for Microbubble-mediated Transcranial Therapy and Simultaneous Cavitation Mapping Physics in Medicine and Biology. 12, 2016 | Pubmed ID: 27845920 A Numerical Study on the Oblique Focus in MR-guided Transcranial Focused Ultrasound Physics in Medicine and Biology. Nov, 2016 | Pubmed ID: 27779134 Registration of Human Skull Computed Tomography Data to an Ultrasound Treatment Space Using a Sparse High Frequency Ultrasound Hemispherical Array Medical Physics. Sep, 2016 | Pubmed ID: 27587036 A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor The New England Journal of Medicine. Aug, 2016 | Pubmed ID: 27557301 Image-guided Ultrasound Phased Arrays Are a Disruptive Technology for Non-invasive Therapy Physics in Medicine and Biology. 09, 2016 | Pubmed ID: 27494561 Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability PloS One. 2016 | Pubmed ID: 27459643 Magnetic Resonance-Guided High-Intensity Focused Ultrasound Hyperthermia for Recurrent Rectal Cancer: MR Thermometry Evaluation and Preclinical Validation International Journal of Radiation Oncology, Biology, Physics. 07, 2016 | Pubmed ID: 27209510 Magnetic Resonance-guided High-intensity Focused Ultrasound Combined with Radiotherapy for Palliation of Head and Neck Cancer-a Pilot Study Journal of Therapeutic Ultrasound. 2016 | Pubmed ID: 27042308 Early Treatment of HER2-amplified Brain Tumors with Targeted NK-92 Cells and Focused Ultrasound Improves Survival Neuro-oncology. 07, 2016 | Pubmed ID: 26819443 A Review of Ablative Techniques in the Treatment of Breast Fibroadenomata Journal of Therapeutic Ultrasound. 2016 | Pubmed ID: 26788322 Comparison of Analytical and Numerical Approaches for CT-based Aberration Correction in Transcranial Passive Acoustic Imaging Physics in Medicine and Biology. Jan, 2016 | Pubmed ID: 26605827 Microbubble-Assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 26486344 Combined Therapeutic and Monitoring Ultrasonic Catheter For Cardiac Ablation Therapies Ultrasound in Medicine & Biology. Jan, 2016 | Pubmed ID: 26431798 Frequency Considerations for Deep Ablation with High-intensity Focused Ultrasound: A Simulation Study Medical Physics. Aug, 2015 | Pubmed ID: 26233216 Experimental Demonstration of Passive Acoustic Imaging in the Human Skull Cavity Using CT-based Aberration Corrections Medical Physics. Jul, 2015 | Pubmed ID: 26133635 Quantitative MRI in a Non-surgical Model of Cervical Spinal Cord Injury NMR in Biomedicine. Aug, 2015 | Pubmed ID: 26053102 Focused Ultrasound-mediated Drug Delivery Through the Blood-brain Barrier Expert Review of Neurotherapeutics. May, 2015 | Pubmed ID: 25936845 Emerging Non-cancer Applications of Therapeutic Ultrasound International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2015 | Pubmed ID: 25792225 Gene Delivery to the Spinal Cord Using MRI-guided Focused Ultrasound Gene Therapy. Jul, 2015 | Pubmed ID: 25781651 A Novel, Flat, Electronically-steered Phased Array Transducer for Tissue Ablation: Preliminary Results Physics in Medicine and Biology. Mar, 2015 | Pubmed ID: 25683789 Hyperthermia-mediated Doxorubicin Release from Thermosensitive Liposomes Using MR-HIFU: Therapeutic Effect in Rabbit Vx2 Tumours International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2015 | Pubmed ID: 25582131 Microbubbles and Blood-brain Barrier Opening: a Numerical Study on Acoustic Emissions and Wall Stress Predictions IEEE Transactions on Bio-medical Engineering. May, 2015 | Pubmed ID: 25546853 Modeling Localized Delivery of Doxorubicin to the Brain Following Focused Ultrasound Enhanced Blood-brain Barrier Permeability Physics in Medicine and Biology. Oct, 2014 | Pubmed ID: 25230100 Alzheimer Disease in a Mouse Model: MR Imaging-guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-brain Barrier and Improves Pathologic Abnormalities and Behavior Radiology. Dec, 2014 | Pubmed ID: 25222068 Analysis of Focused Ultrasound-induced Blood-brain Barrier Permeability in a Mouse Model of Alzheimer's Disease Using Two-photon Microscopy Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2014 | Pubmed ID: 25107692 High-intensity Focused Ultrasound Sonothrombolysis: the Use of Perfluorocarbon Droplets to Achieve Clot Lysis at Reduced Acoustic Power Ultrasound in Medicine & Biology. Sep, 2014 | Pubmed ID: 25023095 Simulation Study of the Effects of Near- and Far-field Heating During Focused Ultrasound Uterine Fibroid Ablation Using an Electronically Focused Phased Array: A Theoretical Analysis of Patient Safety Medical Physics. Jul, 2014 | Pubmed ID: 24989412 A Non-surgical Model of Cervical Spinal Cord Injury Induced with Focused Ultrasound and Microbubbles Journal of Neuroscience Methods. Sep, 2014 | Pubmed ID: 24970578 Intracranial Applications of Magnetic Resonance-guided Focused Ultrasound Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jul, 2014 | Pubmed ID: 24850310 Three-dimensional Transcranial Ultrasound Imaging of Microbubble Clouds Using a Sparse Hemispherical Array IEEE Transactions on Bio-medical Engineering. Apr, 2014 | Pubmed ID: 24658252 Drug Delivery Across the Blood-brain Barrier Using Focused Ultrasound Expert Opinion on Drug Delivery. May, 2014 | Pubmed ID: 24650132 Stimulation of Hippocampal Neurogenesis by Transcranial Focused Ultrasound and Microbubbles in Adult Mice Brain Stimulation. Mar-Apr, 2014 | Pubmed ID: 24629831 Numerical Simulations of Clinical Focused Ultrasound Functional Neurosurgery Physics in Medicine and Biology. Apr, 2014 | Pubmed ID: 24619067 Focused Ultrasound Delivery of Raman Nanoparticles Across the Blood-brain Barrier: Potential for Targeting Experimental Brain Tumors Nanomedicine : Nanotechnology, Biology, and Medicine. Jul, 2014 | Pubmed ID: 24374363 The Evaluation of Steerable Ultrasonic Catheters for Minimally Invasive MRI-guided Cardiac Ablation Magnetic Resonance in Medicine. Aug, 2014 | Pubmed ID: 24114767 The Application of Sparse Arrays in High Frequency Transcranial Focused Ultrasound Therapy: a Simulation Study Medical Physics. Dec, 2013 | Pubmed ID: 24320540 A Super-resolution Ultrasound Method for Brain Vascular Mapping Medical Physics. Nov, 2013 | Pubmed ID: 24320408 Cavitation-based Third Ventriculostomy Using MRI-guided Focused Ultrasound Journal of Neurosurgery. Dec, 2013 | Pubmed ID: 24074494 Drug Delivery to the Brain by Focused Ultrasound Induced Blood-brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-photon Microscopy Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2013 | Pubmed ID: 24008151 Transcranial Passive Acoustic Mapping with Hemispherical Sparse Arrays Using CT-based Skull-specific Aberration Corrections: a Simulation Study Physics in Medicine and Biology. Jul, 2013 | Pubmed ID: 23807573 Creating Brain Lesions with Low-intensity Focused Ultrasound with Microbubbles: a Rat Study at Half a Megahertz Ultrasound in Medicine & Biology. Aug, 2013 | Pubmed ID: 23743099 Amyloid-β Plaque Reduction, Endogenous Antibody Delivery and Glial Activation by Brain-targeted, Transcranial Focused Ultrasound Experimental Neurology. May, 2013 | Pubmed ID: 23707300 Enhancing Drug Delivery for Boron Neutron Capture Therapy of Brain Tumors with Focused Ultrasound Neuro-oncology. Sep, 2013 | Pubmed ID: 23640533 Noninvasive and Targeted Drug Delivery to the Brain Using Focused Ultrasound ACS Chemical Neuroscience. Apr, 2013 | Pubmed ID: 23379618 Focused Ultrasound Delivers Targeted Immune Cells to Metastatic Brain Tumors Cancer Research. Mar, 2013 | Pubmed ID: 23302230 Contrast-enhanced Transcranial Two-dimensional Ultrasound Imaging Using Shear-mode Conversion at Low Frequency Ultrasound in Medicine & Biology. Feb, 2013 | Pubmed ID: 23245822 Antitumor Effects of Combining Docetaxel (taxotere) with the Antivascular Action of Ultrasound Stimulated Microbubbles PloS One. 2012 | Pubmed ID: 23284980 Enhanced Drug Delivery in Rabbit VX2 Tumours Using Thermosensitive Liposomes and MRI-controlled Focused Ultrasound Hyperthermia International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 23153219 Focused Ultrasound for Targeted Delivery of SiRNA and Efficient Knockdown of Htt Expression Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2012 | Pubmed ID: 22921802 High-intensity Focused Ultrasound (HIFU) for Dissolution of Clots in a Rabbit Model of Embolic Stroke PloS One. 2012 | Pubmed ID: 22870315 Targeted Delivery of Self-complementary Adeno-associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-guided Focused Ultrasound Human Gene Therapy. Nov, 2012 | Pubmed ID: 22838844 Improved Anti-tumor Effect of Liposomal Doxorubicin After Targeted Blood-brain Barrier Disruption by MRI-guided Focused Ultrasound in Rat Glioma Ultrasound in Medicine & Biology. Oct, 2012 | Pubmed ID: 22818878 The Design of a Focused Ultrasound Transducer Array for the Treatment of Stroke: a Simulation Study Physics in Medicine and Biology. Aug, 2012 | Pubmed ID: 22800986 Ultrasound Enhanced Drug Delivery to the Brain and Central Nervous System International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 22621739 Overview of Therapeutic Ultrasound Applications and Safety Considerations Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Apr, 2012 | Pubmed ID: 22441920 Hyperthermia in Bone Generated with MR Imaging-controlled Focused Ultrasound: Control Strategies and Drug Delivery Radiology. Apr, 2012 | Pubmed ID: 22438444 In Vitroおよびin Vivoで高強度集束超音波血栓溶解療法で Investigative Radiology. Feb, 2012 | Pubmed ID: 22373533 MRI誘導集束超音波を用いて脳への治療の可能性を持つ金ナノ粒子の強化された配信 Nanomedicine : Nanotechnology, Biology, and Medicine. Feb, 2012 | Pubmed ID: 22349099 MRイメージング制御集束超音波で生成された骨の温熱療法:コントロール戦略とドラッグデリバリー Radiology. Feb, 2012 | Pubmed ID: 22344400 血液脳関門:アコースティックエミッションベースのコントローラを使用して、リアルタイムフィードバック制御された集束超音波破砕 Radiology. Feb, 2012 | Pubmed ID: 22332065 血液脳関門の集束超音波破砕:分子神経腫瘍学の治療配信するための新しいフロンティア Neurosurgical Focus. Jan, 2012 | Pubmed ID: 22208896 体外血液凝固に閉じ込めにおけるパルス集束超音波誘起変位 IEEE Transactions on Bio-medical Engineering. Mar, 2012 | Pubmed ID: 22194235 実験とシミュレーションに関する研究:大口径、頭蓋MRガイド下集束超音波(MRgFUS)フェーズドアレイの臨床プロトタイプのために人間の頭蓋骨で定在波形成の調査 IEEE Transactions on Bio-medical Engineering. Feb, 2012 | Pubmed ID: 22049360 位相または周波数のマッピングを使用して超次元MR温度測定 Magma (New York, N.Y.). Feb, 2012 | Pubmed ID: 21800192 MRIgHIFU: a Tool for Image-guided Therapeutics Journal of Magnetic Resonance Imaging : JMRI. Sep, 2011 | Pubmed ID: 22896850 集束超音波非侵襲的手術とドラッグデリバリーアプリケーションのための駆動回路 Sensors (Basel, Switzerland). 2011 | Pubmed ID: 22346589 血液脳関門を破壊するためにMRI誘導集束超音波を用いて脳への神経幹細胞の標的デリバリー PloS One. 2011 | Pubmed ID: 22114718 ラット頭頂骨の超音波挿入損失はSubmegahertz周波数での動物の質量に比例するように見える Ultrasound in Medicine & Biology. Nov, 2011 | Pubmed ID: 21925788 熱手術のためのスパース2Dの完全電子制御導波集束超音波フェイズドアレイのユーティリティ:シミュレーションによる検討 Physics in Medicine and Biology. Aug, 2011 | Pubmed ID: 21772081 スカルベース暖房と治療の有効面積:頭蓋低周波超音波療法のシミュレーションと測定 Physics in Medicine and Biology. Aug, 2011 | Pubmed ID: 21734333 ターゲット集束超音波手術用にローカライズされた高調波モーションイメージング Ultrasound in Medicine & Biology. Aug, 2011 | Pubmed ID: 21683514 超音波誘導血液脳関門の開口部に脳血管ダイナミクスの二光子蛍光顕微鏡の研究 Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2011 | Pubmed ID: 21505473 がん領域における集束超音波手術:概要と原理 Radiology. Apr, 2011 | Pubmed ID: 21436096 密接にタイムアウト短パルスを用いた血液脳関門の集束超音波破砕:超音波パラメータと噴射率の影響 Ultrasound in Medicine & Biology. Apr, 2011 | Pubmed ID: 21376455 脳アブレーションと血液脳関門の破壊のためのMRガイド下集束超音波 Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21279624 MRI制御集束超音波ハイパーサーミアを使用したローカル化薬剤放出 International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2011 | Pubmed ID: 21158487 新鮮な摘出人間の頭骨の縦伝達のための音と減衰係数の速度のマルチ周波数特性 Physics in Medicine and Biology. Jan, 2011 | Pubmed ID: 21149950 ダナファーバー癌研究所の研究94から153からの長期結果:温熱療法は、局所進行前立腺癌の治療のための放射線との組み合わせ Cancer. Feb, 2011 | Pubmed ID: 20886629 集束超音波媒介BBBの破壊がAktの活性化の増加に関連付けられて:ラットにおける実験的研究 BMC Neurology. 2010 | Pubmed ID: 21078165 ラットモデルにおける血液脳関門の頭蓋集束超音波破砕上の定在波効果の影響 Physics in Medicine and Biology. Sep, 2010 | Pubmed ID: 20720286 集束超音波治療のためのパーフルオロカーボン液滴のインビトロ特性に Physics in Medicine and Biology. Sep, 2010 | Pubmed ID: 20693614 経頭蓋超音波エクスポージャーを用いた血液脳関門のオープニングでの露光時間と圧力振幅の影響 ACS Chemical Neuroscience. May, 2010 | Pubmed ID: 20563295 頭蓋集束超音波療法の超音波モニタリングのためのPVDFレシーバ IEEE Transactions on Bio-medical Engineering. Sep, 2010 | Pubmed ID: 20515709 画像誘導集束超音波で脳をターゲットに抗体は、アルツハイマー病のTgCRND8マウスモデルにおけるアミロイドβプラーク負荷を軽減 PloS One. 2010 | Pubmed ID: 20485502 超音波治療への暴露中のウサギ脳における造影剤動態 Ultrasound in Medicine & Biology. Jun, 2010 | Pubmed ID: 20447757 ヒトMG-63骨芽細胞におけるWntシグナル伝達の超音波誘導活性 Bone. Aug, 2010 | Pubmed ID: 20435172 集束超音波の間に毛細血管網の中でマイクロバブル付近の温度変化 Physics in Medicine and Biology. Mar, 2010 | Pubmed ID: 20164536 温熱療法·クラシック解説:K. Hynynen、R.ローマー、D.アンら、温熱療法、1987年の国際ジャーナルによる "局所限定温熱治療のためにスキャンされ、集束、複数のトランスデューサー超音波システム '; 3:21-35。 International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Feb, 2010 | Pubmed ID: 20100047 脳腫瘍の頭蓋磁気共鳴イメージングガイド下集束超音波手術:3例の初期所見 Neurosurgery. Feb, 2010 | Pubmed ID: 20087132 集束超音波手術のローカル高調波モーション監視 - シミュレーション·モデル IEEE Transactions on Bio-medical Engineering. Jan, 2010 | Pubmed ID: 19822463 MRI誘導集束超音波治療 Ultrasonics. Feb, 2010 | Pubmed ID: 19818981 非侵襲的頭蓋療法のための大規模超音波フェイズドアレイの横方向モード結合法を用いた実現可能性 IEEE Transactions on Bio-medical Engineering. Jan, 2010 | Pubmed ID: 19695987 In Vitroにおける神経活動電位に焦点を当てた超音波の影響 Ultrasound in Medicine & Biology. Oct, 2009 | Pubmed ID: 19647923 MR音響放射力イメージング:生体内の比較超音波モーショントラッキングに Medical Physics. Jun, 2009 | Pubmed ID: 19610290 小動物モデルにおける集束超音波実験のためのMRI対応システム Medical Physics. May, 2009 | Pubmed ID: 19544806 ローカル高調波運動によって制御されるVX2腫瘍の集束超音波治療 Physics in Medicine and Biology. Jun, 2009 | Pubmed ID: 19436103 心房細動の治療のためにEndoesophagealセクターベースのアレイ用の新しいデザイン:パラメトリックシミュレーション研究 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2009 | Pubmed ID: 19411218 ハイパワー超音波療法のフェーズドアレーのために必要な小さな要素の電気的インピーダンスを低減するカップ横モード IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2009 | Pubmed ID: 19411214 MRIベースの熱線量と子宮筋腫のMRIガイド下集束超音波熱アブレーションの拡散強調画像 Journal of Magnetic Resonance Imaging : JMRI. Feb, 2009 | Pubmed ID: 19161196 頭蓋せん断モードの超音波:結像性能の評価と励起テクニック IEEE Transactions on Medical Imaging. May, 2009 | Pubmed ID: 19150789 血液脳関門を越えて高分子デリバリー Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19085123 ローカル高調波動作を用いた集束超音波手術のin Vivoモニタリングで Ultrasound in Medicine & Biology. Jan, 2009 | Pubmed ID: 18805626 超音波にさらされたMG-63骨芽細胞のゲノムワイドなマイクロアレイ解析 Biorheology. 2008 | Pubmed ID: 18836235 子宮筋腫のMRIガイド下集束超音波手術でReferenceless温度測定の評価 Journal of Magnetic Resonance Imaging : JMRI. Oct, 2008 | Pubmed ID: 18821603 複合ドアレイLHMI·テクニックを使用して病変検出のシミュレーション Ultrasonics. Nov, 2008 | Pubmed ID: 18778843 子宮筋腫:MRイメージング誘導集束超音波手術 - 成功のイメージング予測 Radiology. Oct, 2008 | Pubmed ID: 18695211 血液脳関門の破壊のための集束超音波の応用の進歩と問題点 Ultrasonics. Aug, 2008 | Pubmed ID: 18511095 脳への薬物および遺伝子送達のための超音波 Advanced Drug Delivery Reviews. Jun, 2008 | Pubmed ID: 18486271 アルツハイマー病のマウスモデルにおける分子イメージングと治療薬の超音波検査の強化配信 PloS One. 2008 | Pubmed ID: 18478109 脳微小血管内皮細胞のタイトジャンクションの整合性に超音波造影剤と応用集束超音波の効果 Ultrasound in Medicine & Biology. Jul, 2008 | Pubmed ID: 18378064 超音波診断の胎児の熱的効果 Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Apr, 2008 | Pubmed ID: 18359908 集束超音波誘起血液脳関門の破壊の音響パラメータと超音波造影剤の投与の効果 Ultrasound in Medicine & Biology. Jun, 2008 | Pubmed ID: 18294757 集束超音波とマイクロバブル循環前もって形成によって誘起された血液脳関門の破壊はメカニカルインデックスによって特徴付けられたように見える Ultrasound in Medicine & Biology. May, 2008 | Pubmed ID: 18207311 真の同時超音波および磁気共鳴イメージングモダリティイメージングの進展 IEEE Transactions on Medical Imaging. Dec, 2007 | Pubmed ID: 18092742 せん断モード変換を用いた集束デバイスを使用した近頭蓋骨の脳組織の治療:数値的研究 Physics in Medicine and Biology. Dec, 2007 | Pubmed ID: 18065841 ラインスキャンエコープラナー分光イメージングによる乳がんの温度マッピングの考慮事項 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2007 | Pubmed ID: 18046702 せん断波伝送方式を使用してTransskull流体検出のためのコンピュータ制御超音波パルサーレシーバ·システム IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Sep, 2007 | Pubmed ID: 17941383 ブタモデルにおける頭蓋骨のサウンド·オン·スピード乾燥の影響 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Aug, 2007 | Pubmed ID: 17703676 数値解析:2次元配列Endoesophagealデバイスを使用して集束超音波と左心房の肺静脈周囲の周病変形成 Physics in Medicine and Biology. Aug, 2007 | Pubmed ID: 17671344 集束超音波によるゲルトンネルのマイクロバブルのキャビテーション閾値 Ultrasound in Medicine & Biology. Oct, 2007 | Pubmed ID: 17590501 Clinical Applications of Focused Ultrasound-the Brain International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2007 | Pubmed ID: 17578343 体外設定でのソノポレーション効率に影響を与える主要な要因:ソノポレーションの定在波の重要性 Biochemical and Biophysical Research Communications. Aug, 2007 | Pubmed ID: 17568561 中枢神経系悪性腫瘍の化学療法配信の問題:リアリティチェック Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2007 | Pubmed ID: 17538176 子宮筋腫:MRイメージング誘導集束超音波手術 - さまざまな治療プロトコルの結果 Radiology. Jun, 2007 | Pubmed ID: 17446521 高密度集束超音波アレイのための新しいフェーズの割り当てプロトコルと駆動システム IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Apr, 2007 | Pubmed ID: 17441588 MRI誘導集束超音波を用いた治療レベルでのラット脳へのドキソルビシンの標的デリバリー International Journal of Cancer. Journal International Du Cancer. Aug, 2007 | Pubmed ID: 17437269 ターゲット血液脳関門破壊用のDefinityと組み合わせることで超音波パルスの使用:フィージビリティ·スタディ Ultrasound in Medicine & Biology. Apr, 2007 | Pubmed ID: 17337109 マウス脳におけるin Vivo光イメージングと超音波治療のためのモジュラー設計 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Feb, 2007 | Pubmed ID: 17328340 超音波誘導におけるBakの活性化、JNK-およびBcl-2によるP38非依存性アポトーシスとその抑制 Biochemical and Biophysical Research Communications. Feb, 2007 | Pubmed ID: 17188240 脳に血液脳の中断や治療分子の送達のための集束超音波 Expert Opinion on Drug Delivery. Jan, 2007 | Pubmed ID: 17184160 超音波/ Optisonの多光子イメージング、in Vivoで脳に及ぼす影響を媒介 Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2007 | Pubmed ID: 16685254 集束超音波とOptisonのウサギ脳におけるin Vivoでのアポトーシスの誘導 Ultrasound in Medicine & Biology. Dec, 2006 | Pubmed ID: 17169704 臨床MRI誘導集束超音波システムの品質保証とシステムの安定性:4年間の経験 Medical Physics. Nov, 2006 | Pubmed ID: 17153409 リニア超音波フェイズドアレイを用いて組織の高調波運動を誘導するための最適な方法の検討 - シミュレーションによる検討 Ultrasonic Imaging. Apr, 2006 | Pubmed ID: 17094690 画像誘導ブリガムでの脳神経外科および女性の病院 IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. Sep-Oct, 2006 | Pubmed ID: 17020201 低電力レベルでの脳病変を作成するための集束超音波とマイクロバブル造影剤:MRイメージングとウサギにおける組織学的研究 Radiology. Oct, 2006 | Pubmed ID: 16990673 集束超音波誘発後の脳動脈は血液脳関門のオープニングキャピラリと静脈より血液を媒介とするトレーサー分子のより積極的な小胞輸送を表示する Ultrasound in Medicine & Biology. Sep, 2006 | Pubmed ID: 16965980 260 KHzの超音波バーストのために血液脳関門の焦点破壊:分子イメージングと標的薬物送達のための方法 Journal of Neurosurgery. Sep, 2006 | Pubmed ID: 16961141 超音波エラストグラフィで使用される音響放射力により誘導される血管壁にローカライズされた高調波運動のシミュレーション Physics in Medicine and Biology. Sep, 2006 | Pubmed ID: 16953044 超音波は、ウシ、プライマリ軟骨細胞のプロテオグリカン合成を刺激 Biorheology. 2006 | Pubmed ID: 16912400 MRI誘導集束超音波誘起血液脳関門の破壊によってマウス脳へのハーセプチンの非侵襲的局在配信 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16868082 2-D中心に、超音波フェイズドアレイを用いた非侵襲性の経食道心熱アブレーション:シミュレーションによる検討 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Jun, 2006 | Pubmed ID: 16846146 子宮筋腫:集束超音波熱焼灼時のMRイメージングベースの温度測定と熱線量 Radiology. Jul, 2006 | Pubmed ID: 16793983 月経周期の位相は、子宮筋腫のMRガイド下集束超音波手術に影響しますか? European Journal of Radiology. Aug, 2006 | Pubmed ID: 16766153 脳のMRI誘導侵襲手術のためのフェーズドアレイ超音波システムの前臨床試験 - 霊長類の研究 European Journal of Radiology. Aug, 2006 | Pubmed ID: 16716552 ポルフィリン誘導Sonodynamic効果のメカニズム:温熱療法の可能性の役割 Radiation Research. Mar, 2006 | Pubmed ID: 16494518 MRI誘導集束超音波による血液脳関門を介して抗体の標的デリバリー Biochemical and Biophysical Research Communications. Feb, 2006 | Pubmed ID: 16403441 集束超音波とMRI誘導目標と血液脳関門の破壊:ウサギにおける組織学的所見 Ultrasound in Medicine & Biology. Nov, 2005 | Pubmed ID: 16286030 位相と振幅の補正と経頭蓋超音波フォーカス再建 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Sep, 2005 | Pubmed ID: 16285450 局所進行前立腺癌の治療における放射線と組み合わせて温熱療法は、Favourable毒性プロファイルに関連付けられている International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Nov, 2005 | Pubmed ID: 16278168 人間の頭皮の毛のために音響透過損失とフィールドの改造 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Aug, 2005 | Pubmed ID: 16245611 MRイメージング制御集束超音波アブレーション:非侵襲的画像誘導手術 Magnetic Resonance Imaging Clinics of North America. Aug, 2005 | Pubmed ID: 16084419 マイクロバブルが強化された集束超音波を用いたsiRNAの細胞内送達のための新しい方法 Biochemical and Biophysical Research Communications. Sep, 2005 | Pubmed ID: 16081042 トランス頭蓋超音波手術と治療のための磁気共鳴イメージングと互換性のある、大規模アレイ Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Aug, 2005 | Pubmed ID: 16040827 超音波手術のパスの最適化をスキャンする Physics in Medicine and Biology. Aug, 2005 | Pubmed ID: 16030378 腹部集束超音波手術の焦点ビーム歪みと治療計画 Medical Physics. May, 2005 | Pubmed ID: 15984679 MRI誘導超音波加熱では、イヌ前立腺における外因性ルシフェラーゼの空間的制御が可能 Ultrasound in Medicine & Biology. Jul, 2005 | Pubmed ID: 15972202 音響位相を決定するための新しい超音波法は、頭蓋骨によるシフト Ultrasound in Medicine & Biology. Jun, 2005 | Pubmed ID: 15936493 マイクロバブルが強化された超音波によるBakのBH3ペプチドの細胞内送達 Pharmaceutical Research. May, 2005 | Pubmed ID: 15906165 連続波超音波伝送のフル波ヘルムホルツモデル IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2005 | Pubmed ID: 15857048 低周波での頭蓋集束超音波ビーム伝搬の数値解析 Physics in Medicine and Biology. Apr, 2005 | Pubmed ID: 15815098 トランス頭蓋骨Sonicationsに適した周波数での非侵襲的集束超音波によるローカルおよび可逆血液脳関門の破壊 NeuroImage. Jan, 2005 | Pubmed ID: 15588592 磁気共鳴イメージングガイド下集束超音波を用いた肝細胞癌の非侵襲的熱的アブレーション Gastroenterology. Nov, 2004 | Pubmed ID: 15508090 頭蓋集束超音波手術中に頭蓋骨に熱蒸着のパターン IEEE Transactions on Bio-medical Engineering. Oct, 2004 | Pubmed ID: 15490817 血液脳関門のオープニングの細胞メカニズムはマイクロバブルの存在下での超音波により誘起される Ultrasound in Medicine & Biology. Jul, 2004 | Pubmed ID: 15313330 脳の非侵襲的焦点手術のためのアレイシステムを段階的に500の要素超音波:ex Vivoでの人間の頭骨の予備的なウサギの試験 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2004 | Pubmed ID: 15236372 集束超音波により誘起されたリンパ芽球におけるアポトーシスシグナル FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2004 | Pubmed ID: 15231731 乳房の超音波手術の熱線量最適化のためのシミュレーション研究 Medical Physics. May, 2004 | Pubmed ID: 15191322 スカルの超音波吸収によって生成暖房のMRIモニタリング:豚のin Vivo試験で Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2004 | Pubmed ID: 15122691 ウサギ脳における熱誘起血液脳関門の破壊と脳組織の損傷のしきい値のMRIの検討 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2004 | Pubmed ID: 15122673 ガラスナマズの超音波誘導生物学的効果の光学的モニタリング Ultrasound in Medicine & Biology. Jan, 2004 | Pubmed ID: 14962610 熱活性化リポソームMR造影剤:ウサギの肝臓と腎臓におけるインビボの結果、初期 Radiology. Mar, 2004 | Pubmed ID: 14764890 代謝シグナルと内部参照脳温度イメージングの可能性 Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine. Apr, 2003 | Pubmed ID: 16210815 層膜媒体を前方平面投影 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Dec, 2003 | Pubmed ID: 14761040 連続波超音波場におけるハイドロフォンにより異常のモデリング IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Nov, 2003 | Pubmed ID: 14682632 ローカライズされた高調波モーションイメージング:理論、シミュレーションと実験 Ultrasound in Medicine & Biology. Oct, 2003 | Pubmed ID: 14597337 試験管内の液体パーフルオロカーボン液滴の超音波を介したキャビテーションしきい値 Ultrasound in Medicine & Biology. Sep, 2003 | Pubmed ID: 14553814 温度による弾性率変化のモニタリングに超音波刺激によるアコースティック·エミッションの使用 Ultrasonics. Jul, 2003 | Pubmed ID: 12788215 脳のMRIガイド下集束超音波手術:霊長類モデルでのテスト Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jun, 2003 | Pubmed ID: 12768598 超音波造影剤(Optison)の存在下で超音波のバーストによって誘起されたウサギの脳損傷のしきい値 Ultrasound in Medicine & Biology. Mar, 2003 | Pubmed ID: 12706199 子宮筋腫のMRIガイド下集束超音波手術:フィージビリティ·スタディ Radiology. Mar, 2003 | Pubmed ID: 12616023 研究室間の音響パワー測定 Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Feb, 2003 | Pubmed ID: 12562125 脳腫瘍に対する術中磁気共鳴イメージングおよび磁気共鳴イメージング誘導療法 Neuroimaging Clinics of North America. Nov, 2002 | Pubmed ID: 12687918 遺伝的アルゴリズムの最適化に基づいて、頭蓋骨に音の伝わる速さのための統一モデル Physics in Medicine and Biology. Nov, 2002 | Pubmed ID: 12476974 大フォーカルスポットを使用して集束超音波手術のバイオ音響熱レンズ効果と非線形伝搬:パラメトリックスタディ Physics in Medicine and Biology. Jun, 2002 | Pubmed ID: 12108775 放射線と温熱療法の局所進行前立腺癌の治療における熱線量パラメータを持つ直腸毒性の関連 International Journal of Radiation Oncology, Biology, Physics. Jul, 2002 | Pubmed ID: 12095557 物理的なスカルのプロパティによる超音波の位相の相関 Ultrasound in Medicine & Biology. May, 2002 | Pubmed ID: 12079698 磁気共鳴画像誘導集束超音波手術 Cancer Journal (Sudbury, Mass.). May-Jun, 2002 | Pubmed ID: 12075696 マイクロレシーバーガイド頭蓋ビームステアリング IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Apr, 2002 | Pubmed ID: 11989700 超音波刺激アコースティック·エミッションの温度依存性 Ultrasound in Medicine & Biology. Mar, 2002 | Pubmed ID: 11978413 集束超音波手術のために最適な電力を予測するための定量的温度画像の用途:ウサギ筋肉と脳の生体検査で Medical Physics. Mar, 2002 | Pubmed ID: 11929019 頭蓋集束超音波のシミュレーションにおけるパラメータ誤差の影響 Physics in Medicine and Biology. Jan, 2002 | Pubmed ID: 11814226 Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery Ultrasound in Medicine & Biology. | Pubmed ID: 32165014 リアルタイムの生体内多光子顕微鏡で、血液脳関門透過性を高める、集中超音波治療とマイクロバブル治療を可視化 Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6 1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto JoVE 62235 Bioengineering 医学的に難治性本態性振戦患者に対する MRI ガイド下集束超音波視床 Ying Meng1, Yuexi Huang2, Benjamin Solomon2, Kullervo Hynynen2, Nadia Scantlebury1, Michael L. Schwartz1, Nir Lipsman1 1Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2Sunnybrook Research Institute, Sunnybrook Health Sciences Centre JoVE 56365 Medicine ラットモデルでの経頭蓋集束超音波を用いた血液脳関門のMRI誘導破壊 Meaghan A. O'Reilly1, Adam C. Waspe1,2, Rajiv Chopra1,2, Kullervo Hynynen1,3 1Imaging Research, Sunnybrook Research Institute, 2Department of Medical Biophysics, University of Toronto, 3Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto JoVE 3555 Medicine
リアルタイムの生体内多光子顕微鏡で、血液脳関門透過性を高める、集中超音波治療とマイクロバブル治療を可視化 Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6 1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto JoVE 62235 Bioengineering
医学的に難治性本態性振戦患者に対する MRI ガイド下集束超音波視床 Ying Meng1, Yuexi Huang2, Benjamin Solomon2, Kullervo Hynynen2, Nadia Scantlebury1, Michael L. Schwartz1, Nir Lipsman1 1Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2Sunnybrook Research Institute, Sunnybrook Health Sciences Centre JoVE 56365 Medicine
ラットモデルでの経頭蓋集束超音波を用いた血液脳関門のMRI誘導破壊 Meaghan A. O'Reilly1, Adam C. Waspe1,2, Rajiv Chopra1,2, Kullervo Hynynen1,3 1Imaging Research, Sunnybrook Research Institute, 2Department of Medical Biophysics, University of Toronto, 3Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto JoVE 3555 Medicine