Larisa Y. Poluektova Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical Center Biography Publications Institution JoVE Articles Larisa Y. Poluektova has not added a biography. If you are Larisa Y. Poluektova and would like to personalize this page please email our Author Liaison for assistance. Publications Eluted 25-hydroxyvitamin D from Radially Aligned Nanofiber Scaffolds Enhances Cathelicidin Production While Reducing Inflammatory Response in Human Immune System-engrafted Mice Acta Biomaterialia. Aug, 2019 | Pubmed ID: 31386930 Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice Nature Communications. 07, 2019 | Pubmed ID: 31266936 Small Molecule ONC201 Inhibits HIV-1 Replication in Macrophages Via FOXO3a and TRAIL Antiviral Research. Aug, 2019 | Pubmed ID: 31158413 Acetaldehyde Suppresses the Display of HBV-MHC Class I Complexes on HBV-expressing Hepatocytes American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2019 | Pubmed ID: 31141391 Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice Frontiers in Immunology. 2019 | Pubmed ID: 30873181 Human Interleukin-34 Facilitates Microglia-like Cell Differentiation and Persistent HIV-1 Infection in Humanized Mice Molecular Neurodegeneration. 03, 2019 | Pubmed ID: 30832693 Human Immunodeficiency Virus and Hepatotropic Viruses Co-morbidities As the Inducers of Liver Injury Progression World Journal of Gastroenterology. Jan, 2019 | Pubmed ID: 30700937 Human-like NSG Mouse Glycoproteins Sialylation Pattern Changes the Phenotype of Human Lymphocytes and Sensitivity to HIV-1 Infection BMC Immunology. 01, 2019 | Pubmed ID: 30616506 Liver As a Target of Human Immunodeficiency Virus Infection World Journal of Gastroenterology. Nov, 2018 | Pubmed ID: 30479460 Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol As a Second Hit Biomolecules. 10, 2018 | Pubmed ID: 30322122 Persistent EcoHIV Infection Induces Nigral Degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated Mice Journal of Neurovirology. Aug, 2018 | Pubmed ID: 29594983 Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice The Journal of Pharmacology and Experimental Therapeutics. 05, 2018 | Pubmed ID: 29476044 Creation of a Long-acting Nanoformulated Dolutegravir Nature Communications. 02, 2018 | Pubmed ID: 29402886 Human Hepatocyte Depletion in the Presence of HIV-1 Infection in Dual Reconstituted Humanized Mice Biology Open. Feb, 2018 | Pubmed ID: 29361613 Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains Disease Models & Mechanisms. 12, 2017 | Pubmed ID: 29084769 Sonic Hedgehog Mimetic Prevents Leukocyte Infiltration into the CNS During Acute HIV Infection Scientific Reports. 08, 2017 | Pubmed ID: 28852071 A Mature Macrophage is a Principal HIV-1 Cellular Reservoir in Humanized Mice After Treatment with Long Acting Antiretroviral Therapy Retrovirology. 03, 2017 | Pubmed ID: 28279181 Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18 Alcoholism, Clinical and Experimental Research. 11, 2016 | Pubmed ID: 27716962 Neuropharmacologic Approaches to Restore the Brain's Microenvironment Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 09, 2016 | Pubmed ID: 27352074 Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice Scientific Reports. 05, 2016 | Pubmed ID: 27241024 Simple and Reliable Genotyping Protocol for Mouse Prkdc(SCID) Mutation Journal of Immunological Methods. Apr, 2016 | Pubmed ID: 26851521 Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary AIDS Research and Human Retroviruses. Feb, 2016 | Pubmed ID: 26670361 The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-acting Antiretroviral Therapy Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2016 | Pubmed ID: 26472049 Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice Molecular Neurobiology. 07, 2016 | Pubmed ID: 26063593 Influence of Age, Irradiation and Humanization on NSG Mouse Phenotypes Biology Open. Sep, 2015 | Pubmed ID: 26353862 Liver-targeted Antiviral Peptide Nanocomplexes As Potential Anti-HCV Therapeutics Biomaterials. Nov, 2015 | Pubmed ID: 26298393 Pharmacodynamics of Long-acting Folic Acid-receptor Targeted Ritonavir-boosted Atazanavir Nanoformulations Biomaterials. Feb, 2015 | Pubmed ID: 25522973 Associations Between Brain Microstructures, Metabolites, and Cognitive Deficits During Chronic HIV-1 Infection of Humanized Mice Molecular Neurodegeneration. Dec, 2014 | Pubmed ID: 25523827 Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-conditioned UPA-NOG Mice The American Journal of Pathology. Jan, 2014 | Pubmed ID: 24200850 Nano-NRTIs Demonstrate Low Neurotoxicity and High Antiviral Activity Against HIV Infection in the Brain Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2014 | Pubmed ID: 23845925 Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2013 | Pubmed ID: 23729245 Combinatorial Assessments of Brain Tissue Metabolomics and Histopathology in Rodent Models of Human Immunodeficiency Virus Infection Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2013 | Pubmed ID: 23702663 Antiviral Peptide Nanocomplexes As a Potential Therapeutic Modality for HIV/HCV Co-infection Biomaterials. May, 2013 | Pubmed ID: 23403120 Long-acting Nanoformulated Antiretroviral Therapy Elicits Potent Antiretroviral and Neuroprotective Responses in HIV-1-infected Humanized Mice AIDS (London, England). Nov, 2012 | Pubmed ID: 22824628 Cisplatin-loaded Core Cross-linked Micelles: Comparative Pharmacokinetics, Antitumor Activity, and Toxicity in Mice International Journal of Nanomedicine. 2012 | Pubmed ID: 22745537 人性化的小鼠能反映艾滋病毒相关认知障碍的复杂的病理吗? Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jan, 2012 | Pubmed ID: 22222956 IL-23 in Infections, Inflammation, Autoimmunity and Cancer: Possible Role in HIV-1 and AIDS Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2012 | Pubmed ID: 21947740 期间逐步 Hiv-1 感染的人性化小鼠神经元完整性损失。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21368026 Nano-NRTIs: Efficient Inhibitors of HIV Type-1 in Macrophages with a Reduced Mitochondrial Toxicity Antiviral Chemistry & Chemotherapy. Oct, 2010 | Pubmed ID: 21045256 CD8 + 细胞消耗加快艾滋病毒 1 人性化小鼠的免疫病理学。 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010 | Pubmed ID: 20495069 Protection from the Toxicity of Diisopropylfluorophosphate by Adeno-associated Virus Expressing Acetylcholinesterase Toxicology and Applied Pharmacology. Jul, 2006 | Pubmed ID: 16443250 人类免疫缺陷病毒 1 脑炎小鼠中锂的神经保护作用机制。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16162919 巨噬细胞炎症因子影响海马可塑性和艾滋病毒 1 脑炎小鼠模型中的神经元发展。 Glia. Dec, 2005 | Pubmed ID: 16078235 下丘脑事件遵循感染艾滋病毒 1 巨噬细胞的免疫介导的自适应消除: 病毒性脑炎的小鼠模型的研究。 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15187141 脑单核吞噬细胞 OTK18 表达相似艾滋病毒 1 脑炎严重的程度。 Journal of Neuroimmunology. May, 2004 | Pubmed ID: 15081264 丙戊酸钠的人类免疫缺陷病毒 1 脑炎的小鼠模型中的神经保护活动。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14534250 一代的细胞毒性 T 细胞对病毒感染人类的大脑巨噬细胞中的艾滋病毒 1 脑炎的小鼠模型。 Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002 | Pubmed ID: 11937550 建立与艾滋病毒相关的肝脏发病机制的双人性化TK-NOG小鼠模型 Raghubendra Singh Dagur1, Weimin Wang1, Edward Makarov1, Yimin Sun2, Larisa Y. Poluektova1 1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 2Department of Pathology and Microbiology, University of Nebraska Medical Center JoVE 58645 Immunology and Infection
建立与艾滋病毒相关的肝脏发病机制的双人性化TK-NOG小鼠模型 Raghubendra Singh Dagur1, Weimin Wang1, Edward Makarov1, Yimin Sun2, Larisa Y. Poluektova1 1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 2Department of Pathology and Microbiology, University of Nebraska Medical Center JoVE 58645 Immunology and Infection