Laurent Younes Center for Imaging Science Johns Hopkins University Biography Publications Institution JoVE Articles Laurent Younes has not added a biography. If you are Laurent Younes and would like to personalize this page please email our Author Liaison for assistance. Publications Computational Anatomy and Diffeomorphometry: A Dynamical Systems Model of Neuroanatomy in the Soft Condensed Matter Continuum Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Jun, 2018 | Pubmed ID: 29862670 Digitizing Omics Profiles by Divergence from a Baseline Proceedings of the National Academy of Sciences of the United States of America. May, 2018 | Pubmed ID: 29666255 Mapping the Order and Pattern of Brain Structural MRI Changes Using Change-point Analysis in Premanifest Huntington's Disease Human Brain Mapping. Oct, 2017 | Pubmed ID: 28657159 Parametric Surface Diffeomorphometry for Low Dimensional Embeddings of Dense Segmentations and Imagery IEEE Transactions on Pattern Analysis and Machine Intelligence. Jun, 2017 | Pubmed ID: 27295651 Linking White Matter and Deep Gray Matter Alterations in Premanifest Huntington Disease NeuroImage. Clinical. 2016 | Pubmed ID: 27104139 Shape Analysis of Hypertrophic and Hypertensive Heart Disease Using MRI-based 3D Surface Models of Left Ventricular Geometry Medical Image Analysis. Apr, 2016 | Pubmed ID: 26766206 Hamiltonian Systems and Optimal Control in Computational Anatomy: 100 Years Since D'Arcy Thompson Annual Review of Biomedical Engineering. 2015 | Pubmed ID: 26643025 Network Neurodegeneration in Alzheimer's Disease Via MRI Based Shape Diffeomorphometry and High-Field Atlasing Frontiers in Bioengineering and Biotechnology. 2015 | Pubmed ID: 26284236 Relationship of Medial Temporal Lobe Atrophy, APOE Genotype, and Cognitive Reserve in Preclinical Alzheimer's Disease Human Brain Mapping. Jul, 2015 | Pubmed ID: 25879865 Morphometry of the Amygdala in Schizophrenia and Psychotic Bipolar Disorder Schizophrenia Research. May, 2015 | Pubmed ID: 25766598 Visual Turing Test for Computer Vision Systems Proceedings of the National Academy of Sciences of the United States of America. Mar, 2015 | Pubmed ID: 25755262 The Diffeomorphometry of Regional Shape Change Rates and Its Relevance to Cognitive Deterioration in Mild Cognitive Impairment and Alzheimer's Disease Human Brain Mapping. Jun, 2015 | Pubmed ID: 25644981 Amygdalar Atrophy in Symptomatic Alzheimer's Disease Based on Diffeomorphometry: the BIOCARD Cohort Neurobiology of Aging. Jan, 2015 | Pubmed ID: 25444602 An Argument for Mechanism-based Statistical Inference in Cancer Human Genetics. May, 2015 | Pubmed ID: 25381197 Baseline Shape Diffeomorphometry Patterns of Subcortical and Ventricular Structures in Predicting Conversion of Mild Cognitive Impairment to Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2015 | Pubmed ID: 25318546 Estimating Dense Cardiac 3D Motion Using Sparse 2D Tagged MRI Cross-sections Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2014 | Pubmed ID: 25571140 Inferring Changepoint Times of Medial Temporal Lobe Morphometric Change in Preclinical Alzheimer's Disease NeuroImage. Clinical. 2014 | Pubmed ID: 25101236 Imaging the Evolution of Reactivation Pulmonary Tuberculosis in Mice Using 18F-FDG PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2014 | Pubmed ID: 25082854 Diffeomorphometry and Geodesic Positioning Systems for Human Anatomy Technology. Mar, 2014 | Pubmed ID: 24904924 Shape Abnormalities of Subcortical and Ventricular Structures in Mild Cognitive Impairment and Alzheimer's Disease: Detecting, Quantifying, and Predicting Human Brain Mapping. Aug, 2014 | Pubmed ID: 24443091 Regionally Selective Atrophy of Subcortical Structures in Prodromal HD As Revealed by Statistical Shape Analysis Human Brain Mapping. Mar, 2014 | Pubmed ID: 23281100 A Metamorphosis Distance for Embryonic Cardiac Action Potential Interpolation and Classification Medical Image Computing and Computer-assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 2013 | Pubmed ID: 24505700 The Diffeomorphometry of Temporal Lobe Structures in Preclinical Alzheimer's Disease NeuroImage. Clinical. 2013 | Pubmed ID: 24363990 Identification of Direction in Gene Networks from Expression and Methylation BMC Systems Biology. Nov, 2013 | Pubmed ID: 24182195 Robust Diffeomorphic Mapping Via Geodesically Controlled Active Shapes International Journal of Biomedical Imaging. 2013 | Pubmed ID: 23690757 Learning Multivariate Distributions by Competitive Assembly of Marginals IEEE Transactions on Pattern Analysis and Machine Intelligence. Feb, 2013 | Pubmed ID: 22529323 Amygdala Atrophy in MCI/Alzheimer's Disease in the BIOCARD Cohort Based on Diffeomorphic Morphometry Medical Image Computing and Computer-assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Oct, 2012 | Pubmed ID: 24955432 Principal Components Analysis of Scalar, Vector, and Mesh Vertex Data The Insight Journal. Jan, 2012 | Pubmed ID: 24588002 Left-ventricular Shape Analysis for Predicting Sudden Cardiac Death Risk Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2012 | Pubmed ID: 23366821 Principal Component Based Diffeomorphic Surface Mapping IEEE Transactions on Medical Imaging. Feb, 2012 | Pubmed ID: 21937344 Incorporating User Input in Template-Based Segmentation Proceedings. IEEE International Symposium on Biomedical Imaging. Mar-Apr, 2011 | Pubmed ID: 26146532 Laplace Beltrami Filter on QuadEdge Meshes The Insight Journal. Jul, 2011 | Pubmed ID: 23875180 Diffuse Abnormality of Low to Moderately Organized White Matter in Schizophrenia Brain Connectivity. 2011 | Pubmed ID: 22500774 Multi-modal MRI Analysis with Disease-specific Spatial Filtering: Initial Testing to Predict Mild Cognitive Impairment Patients Who Convert to Alzheimer's Disease Frontiers in Neurology. 2011 | Pubmed ID: 21904533 Whole Brain Diffeomorphic Metric Mapping Via Integration of Sulcal and Gyral Curves, Cortical Surfaces, and Images NeuroImage. May, 2011 | Pubmed ID: 21281722 A Comprehensive Statistical Model for Cell Signaling IEEE/ACM Transactions on Computational Biology and Bioinformatics. May-Jun, 2011 | Pubmed ID: 20855924 A Bayesian Generative Model for Surface Template Estimation International Journal of Biomedical Imaging. 2010 | Pubmed ID: 20885934 Template Registration with Missing Parts: Application to the Segmentation of M. Tuberculosis Infected Lungs Proceedings. IEEE International Symposium on Biomedical Imaging. Jun-Jul, 2009 | Pubmed ID: 26146531 Cardiac Motion Analysis in Ischemic and Non-Ischemic Cardiomyopathy Using Parallel Transport Proceedings / IEEE International Symposium on Biomedical Imaging: from Nano to Macro. IEEE International Symposium on Biomedical Imaging. Jun, 2009 | Pubmed ID: 20119497 Neuroanatomical Asymmetry Patterns in Individuals with Schizophrenia and Their Non-psychotic Siblings NeuroImage. Oct, 2009 | Pubmed ID: 19481156 Multi-contrast Large Deformation Diffeomorphic Metric Mapping for Diffusion Tensor Imaging NeuroImage. Aug, 2009 | Pubmed ID: 19398016 Computational Method for Identifying and Quantifying Shape Features of Human Left Ventricular Remodeling Annals of Biomedical Engineering. Jun, 2009 | Pubmed ID: 19322659 Evolutions Equations in Computational Anatomy NeuroImage. Mar, 2009 | Pubmed ID: 19059343 Time Sequence Diffeomorphic Metric Mapping and Parallel Transport Track Time-dependent Shape Changes NeuroImage. Mar, 2009 | Pubmed ID: 19041947 Landmark-referenced Voxel-based Analysis of Diffusion Tensor Images of the Brainstem White Matter Tracts: Application in Patients with Middle Cerebral Artery Stroke NeuroImage. Feb, 2009 | Pubmed ID: 18852056 Large Deformation Diffeomorphic Metric Curve Mapping International Journal of Computer Vision. Dec, 2008 | Pubmed ID: 20419045 DIFFEOMORPHIC SURFACE FLOWS: A NOVEL METHOD OF SURFACE EVOLUTION SIAM Journal on Applied Mathematics. Jan, 2008 | Pubmed ID: 20016768 Transport of Relational Structures in Groups of Diffeomorphisms Journal of Mathematical Imaging and Vision. Sep, 2008 | Pubmed ID: 19809583 Bayesian Template Estimation in Computational Anatomy NeuroImage. Aug, 2008 | Pubmed ID: 18514544 Quantitative Cortical Mapping of Fractional Anisotropy in Developing Rat Brains The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2008 | Pubmed ID: 18256263 Parallel Transport in Diffeomorphisms Distinguishes the Time-dependent Pattern of Hippocampal Surface Deformation Due to Healthy Aging and the Dementia of the Alzheimer's Type NeuroImage. Mar, 2008 | Pubmed ID: 18249009 Combining Anatomical Manifold Information Via Diffeomorphic Metric Mappings for Studying Cortical Thinning of the Cingulate Gyrus in Schizophrenia NeuroImage. Sep, 2007 | Pubmed ID: 17613251 Large Deformation Diffeomorphism and Momentum Based Hippocampal Shape Discrimination in Dementia of the Alzheimer Type IEEE Transactions on Medical Imaging. Apr, 2007 | Pubmed ID: 17427733 Diffeomorphic Matching of Diffusion Tensor Images Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Jul, 2006 | Pubmed ID: 20711423 Combining Geodesic Interpolating Splines and Affine Transformations IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society. May, 2006 | Pubmed ID: 16671292 Evidence of Structural Remodeling in the Dyssynchronous Failing Heart Circulation Research. Jan, 2006 | Pubmed ID: 16339482 Large Deformation Diffeomorphic Metric Mapping of Vector Fields IEEE Transactions on Medical Imaging. Sep, 2005 | Pubmed ID: 16156359 Ex Vivo 3D Diffusion Tensor Imaging and Quantification of Cardiac Laminar Structure Magnetic Resonance in Medicine. Oct, 2005 | Pubmed ID: 16149057 Clutter Invariant ATR IEEE Transactions on Pattern Analysis and Machine Intelligence. May, 2005 | Pubmed ID: 15875803 On the Metrics and Euler-lagrange Equations of Computational Anatomy Annual Review of Biomedical Engineering. 2002 | Pubmed ID: 12117763 DIFFEOMORPHIC ACTIVE CONTOURS SIAM Journal on Imaging Sciences. | Pubmed ID: 20814568 Todo cérebro-segmentação e análise de ponto de mudança de anatômico cérebro MRI — aplicação em Premanifest a doença de Huntington Dan Wu1, Andreia V. Faria1, Laurent Younes2,3,4, Christopher A. Ross5, Susumu Mori1,6, Michael I. Miller2,3,7 1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 2Center for Imaging Science, Johns Hopkins University, 3Institute for Computational Medicine, Johns Hopkins University, 4Department of Applied Mathematics and Statistics, Johns Hopkins University, 5Division of Neurobiology, Departments of Psychiatry, Neurology, Neuroscience and Pharmacology, and Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 6F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, 7Department of Biomedical Engineering, Johns Hopkins University JoVE 57256 Medicine
Todo cérebro-segmentação e análise de ponto de mudança de anatômico cérebro MRI — aplicação em Premanifest a doença de Huntington Dan Wu1, Andreia V. Faria1, Laurent Younes2,3,4, Christopher A. Ross5, Susumu Mori1,6, Michael I. Miller2,3,7 1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 2Center for Imaging Science, Johns Hopkins University, 3Institute for Computational Medicine, Johns Hopkins University, 4Department of Applied Mathematics and Statistics, Johns Hopkins University, 5Division of Neurobiology, Departments of Psychiatry, Neurology, Neuroscience and Pharmacology, and Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 6F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, 7Department of Biomedical Engineering, Johns Hopkins University JoVE 57256 Medicine
