Linda M Pilarski Department of Oncology University of Alberta Biography Publications Institution JoVE Articles Linda M Pilarski has not added a biography. If you are Linda M Pilarski and would like to personalize this page please email our Author Liaison for assistance. Publications A Novel Method for Sample Delivery and Testing of Whole Blood: Gel Strip PCR for Point of Care (POC) Molecular Diagnostics Lab on a Chip. Oct, 2013 | Pubmed ID: 23966268 Storing Self-contained Gel Capillary Cassettes for POC Medical Diagnostics Lab on a Chip. Oct, 2013 | Pubmed ID: 23966212 Frequent Occurrence of Highly Expanded but Unrelated B-cell Clones in Patients with Multiple Myeloma PloS One. 2013 | Pubmed ID: 23724106 The Systemic Cytokine Environment is Permanently Altered in Multiple Myeloma PloS One. 2013 | Pubmed ID: 23544044 Aberrant Splicing, Hyaluronan Synthases and Intracellular Hyaluronan As Drivers of Oncogenesis and Potential Drug Targets Current Cancer Drug Targets. May, 2013 | Pubmed ID: 23517594 An Enclosed In-gel PCR Amplification Cassette with Multi-target, Multi-sample Detection for Platform Molecular Diagnostics Lab on a Chip. Jul, 2013 | Pubmed ID: 23471315 Differential Nuclear Organization of Translocation-prone Genes in Nonmalignant B Cells from Patients with T(14;16) As Compared with T(4;14) or T(11;14) Myeloma Genes, Chromosomes & Cancer. Jun, 2013 | Pubmed ID: 23460268 Alteration of Introns in a Hyaluronan Synthase 1 (HAS1) Minigene Convert Pre-mRNA [corrected] Splicing to the Aberrant Pattern in Multiple Myeloma (MM): MM Patients Harbor Similar Changes PloS One. 2013 | Pubmed ID: 23301075 In Non-transplant Patients with Multiple Myeloma, the Pre-treatment Level of Clonotypic Cells Predicts Event-free Survival Molecular Cancer. 2012 | Pubmed ID: 23083101 In Multiple Myeloma, Bone-marrow Lymphocytes Harboring the Same Chromosomal Abnormalities As Autologous Plasma Cells Predict Poor Survival American Journal of Hematology. Jun, 2012 | Pubmed ID: 22495885 Differential Positioning and Close Spatial Proximity of Translocation-prone Genes in Nonmalignant B-cells from Multiple Myeloma Patients Genes, Chromosomes & Cancer. Aug, 2012 | Pubmed ID: 22489023 A Miniaturized and Integrated Gel Post Platform for Multiparameter PCR Detection of Herpes Simplex Viruses from Raw Genital Swabs Lab on a Chip. May, 2012 | Pubmed ID: 22426784 Expression, Adverse Prognostic Significance and Therapeutic Small Molecule Inhibition of Polo-like Kinase 1 in Multiple Myeloma Leukemia Research. Dec, 2011 | Pubmed ID: 21816470 In a Patient with Biclonal Waldenstrom Macroglobulinemia Only One Clone Expands in Three-dimensional Culture and Includes Putative Cancer Stem Cells Leukemia & Lymphoma. Feb, 2011 | Pubmed ID: 21133724 In-gel Technology for PCR Genotyping and Pathogen Detection Analytical Chemistry. Oct, 2010 | Pubmed ID: 20809605 Multiple Myeloma May Include Microvessel Endothelial Cells of Malignant Origin Leukemia & Lymphoma. Apr, 2010 | Pubmed ID: 20233053 Promiscuity of Translocation Partners in Multiple Myeloma Journal of Cellular Biochemistry. Apr, 2010 | Pubmed ID: 20127714 Aberrant Splice Variants of HAS1 (Hyaluronan Synthase 1) Multimerize with and Modulate Normally Spliced HAS1 Protein: a Potential Mechanism Promoting Human Cancer The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19451652 Genetic Abnormalities in Waldenström's Macroglobulinemia Clinical Lymphoma & Myeloma. Mar, 2009 | Pubmed ID: 19362966 The Relationships Among Physiologic Variables, Quality of Life, and Fatigue in Patients with Multiple Myeloma Oncology Nursing Forum. Mar, 2009 | Pubmed ID: 19273410 Altered Expression of Fibronectin and Collagens I and IV in Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Mar, 2009 | Pubmed ID: 19001640 Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells That Persist During Treatment with Rituximab Clinical Medicine. Oncology. 2008 | Pubmed ID: 21892289 Strategies for Enhancing the Speed and Integration of Microchip Genetic Amplification Electrophoresis. Dec, 2008 | Pubmed ID: 19053066 An Integrated Microfluidic Chip for Chromosome Enumeration Using Fluorescence in Situ Hybridization Lab on a Chip. Dec, 2008 | Pubmed ID: 19023479 Inherited and Acquired Variations in the Hyaluronan Synthase 1 (HAS1) Gene May Contribute to Disease Progression in Multiple Myeloma and Waldenstrom Macroglobulinemia Blood. Dec, 2008 | Pubmed ID: 18815290 Analysis of Clonotypic Switch Junctions Reveals Multiple Myeloma Originates from a Single Class Switch Event with Ongoing Mutation in the Isotype-switched Progeny Blood. Sep, 2008 | Pubmed ID: 18577707 A Unique Three-dimensional Model for Evaluating the Impact of Therapy on Multiple Myeloma Blood. Oct, 2008 | Pubmed ID: 18535198 An Inexpensive and Portable Microchip-based Platform for Integrated RT-PCR and Capillary Electrophoresis The Analyst. Mar, 2008 | Pubmed ID: 18299747 The Selective Aurora B Kinase Inhibitor AZD1152 is a Potential New Treatment for Multiple Myeloma British Journal of Haematology. Feb, 2008 | Pubmed ID: 18076711 Establishment of BCWM.1 Cell Line for Waldenström's Macroglobulinemia with Productive in Vivo Engraftment in SCID-hu Mice Experimental Hematology. Sep, 2007 | Pubmed ID: 17761288 Microfluidic Platform for Single Nucleotide Polymorphism Genotyping of the Thiopurine S-methyltransferase Gene to Evaluate Risk for Adverse Drug Events The Journal of Molecular Diagnostics : JMD. Sep, 2007 | Pubmed ID: 17690215 Microfluidic Chips for Detecting the T(4;14) Translocation and Monitoring Disease During Treatment Using Reverse Transcriptase-polymerase Chain Reaction Analysis of IgH-MMSET Hybrid Transcripts The Journal of Molecular Diagnostics : JMD. Jul, 2007 | Pubmed ID: 17591936 Molecular Characterization of Waldenstrom's Macroglobulinemia Reveals Frequent Occurrence of Two B-cell Clones Having Distinct IgH VDJ Sequences Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17404080 Ten Years and Counting: So What Do We Know About T(4;14)(p16;q32) Multiple Myeloma Leukemia & Lymphoma. Nov, 2006 | Pubmed ID: 17107900 Automated Screening Using Microfluidic Chip-based PCR and Product Detection to Assess Risk of BK Virus-associated Nephropathy in Renal Transplant Recipients Electrophoresis. Oct, 2006 | Pubmed ID: 16960845 Impaired Class Switch Recombination (CSR) in Waldenstrom Macroglobulinemia (WM) Despite Apparently Normal CSR Machinery Blood. Apr, 2006 | Pubmed ID: 16317092 SSX Cancer Testis Antigens Are Expressed in Most Multiple Myeloma Patients: Co-expression of SSX1, 2, 4, and 5 Correlates with Adverse Prognosis and High Frequencies of SSX-positive PCs Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2005 | Pubmed ID: 16224274 Sensitive Detection Using Microfluidics Technology of Single Cell PCR Products from High and Low Abundance IgH VDJ Templates in Multiple Myeloma Journal of Immunological Methods. Oct, 2005 | Pubmed ID: 16150455 A Potential Role for Centrosomal Deregulation Within IgH Translocation-positive Myeloma Medical Hypotheses. 2005 | Pubmed ID: 16023302 Identification of Clonotypic IgH VDJ Sequences in Multiple Myeloma Methods in Molecular Medicine. 2005 | Pubmed ID: 15968099 Potential Impact of a Single Nucleotide Polymorphism in the Hyaluronan Synthase 1 Gene in Waldenstrom's Macroglobulinemia Clinical Lymphoma. Mar, 2005 | Pubmed ID: 15794859 Origins of Waldenstrom's Macroglobulinemia: Does It Arise from an Unusual B-cell Precursor? Clinical Lymphoma. Mar, 2005 | Pubmed ID: 15794851 Intronic Splicing of Hyaluronan Synthase 1 (HAS1): a Biologically Relevant Indicator of Poor Outcome in Multiple Myeloma Blood. Jun, 2005 | Pubmed ID: 15731173 Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer Current Drug Targets. Cardiovascular & Haematological Disorders. Feb, 2005 | Pubmed ID: 15720220 Receptor for Hyaluronan-mediated Motility Correlates with Centrosome Abnormalities in Multiple Myeloma and Maintains Mitotic Integrity Cancer Research. Feb, 2005 | Pubmed ID: 15705883 Overexpression of Transcripts Originating from the MMSET Locus Characterizes All T(4;14)(p16;q32)-positive Multiple Myeloma Patients Blood. May, 2005 | Pubmed ID: 15677557 A Combined Dielectrophoresis, Traveling Wave Dielectrophoresis and Electrorotation Microchip for the Manipulation and Characterization of Human Malignant Cells Journal of Microbiological Methods. Sep, 2004 | Pubmed ID: 15279943 RHAMM Expression and Isoform Balance Predict Aggressive Disease and Poor Survival in Multiple Myeloma Blood. Aug, 2004 | Pubmed ID: 15105292 Genetics and Cytogenetics of Multiple Myeloma: a Workshop Report Cancer Research. Feb, 2004 | Pubmed ID: 14989251 Clonotypic IgM V/D/J Sequence Analysis in Waldenstrom Macroglobulinemia Suggests an Unusual B-cell Origin and an Expansion of Polyclonal B Cells in Peripheral Blood Blood. Oct, 2004 | Pubmed ID: 14764523 Discussion on the Safety of 6-mercaptopurine for Childbearing Patients with Inflammatory Bowel Disease: a Retrospective Cohort Study Gastroenterology. Nov, 2003 | Pubmed ID: 14628819 RHAMM is a Centrosomal Protein That Interacts with Dynein and Maintains Spindle Pole Stability Molecular Biology of the Cell. Jun, 2003 | Pubmed ID: 12808028 Improved Resolution with Microchip-based Enhanced Field Inversion Electrophoresis Electrophoresis. Jun, 2003 | Pubmed ID: 12783455 Abnormal Expression of Hyaluronan Synthases in Patients with Waldenstrom's Macroglobulimenia Seminars in Oncology. Apr, 2003 | Pubmed ID: 12720129 The Malignant Clone in Waldenstrom's Macroglobulinemia Seminars in Oncology. Apr, 2003 | Pubmed ID: 12720122 In Multiple Myeloma, T(4;14)(p16;q32) is an Adverse Prognostic Factor Irrespective of FGFR3 Expression Blood. Feb, 2003 | Pubmed ID: 12393535 Clonotypic Myeloma Cells Able to Xenograft Myeloma to Nonobese Diabetic Severe Combined Immunodeficient Mice Copurify with CD34 (+) Hematopoietic Progenitors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2002 | Pubmed ID: 12374689 CD20-directed Serotherapy in Patients with Multiple Myeloma: Biologic Considerations and Therapeutic Applications Journal of Immunotherapy (Hagerstown, Md. : 1997). Jan-Feb, 2002 | Pubmed ID: 11924912 Leukemic B Cells Clonally Identical to Myeloma Plasma Cells Are Myelomagenic in NOD/SCID Mice Experimental Hematology. Mar, 2002 | Pubmed ID: 11882359 Intraclonal Homogeneity of Clonotypic Immunoglobulin M and Diversity of Nonclinical Post-switch Isotypes in Multiple Myeloma: Insights into the Evolution of the Myeloma Clone Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2002 | Pubmed ID: 11839670 प्राथमिक मानव अस्थि मज्जा और उसके Malignancies अध्ययन के लिए एक तीन आयामी ऊतक संस्कृति मॉडल Mukti R. Parikh1, Andrew R. Belch2,3, Linda M Pilarski2,3, Julia Kirshner1 1Department of Biological Sciences, Purdue University, 2Department of Oncology, University of Alberta, 3Cross Cancer Institute JoVE 50947 Medicine
प्राथमिक मानव अस्थि मज्जा और उसके Malignancies अध्ययन के लिए एक तीन आयामी ऊतक संस्कृति मॉडल Mukti R. Parikh1, Andrew R. Belch2,3, Linda M Pilarski2,3, Julia Kirshner1 1Department of Biological Sciences, Purdue University, 2Department of Oncology, University of Alberta, 3Cross Cancer Institute JoVE 50947 Medicine