Lisa M. Coussens

Publications

• Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition
  Cancer Discovery. Jun, 2017  |   Pubmed ID: 28652380
• Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis
  Cell Reports. Apr, 2017  |   Pubmed ID: 28380359
• Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions
  Cellular and Molecular Gastroenterology and Hepatology. Mar, 2017  |   Pubmed ID: 28275683
• Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis
  The Journal of Investigative Dermatology. Feb, 2017  |   Pubmed ID: 27720760
• MicroRNA Regulation of Endothelial TREX1 Reprograms the Tumour Microenvironment
  Nature Communications. Nov, 2016  |   Pubmed ID: 27886180
• AACR Cancer Progress Report 2016
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2016  |   Pubmed ID: 27697776
• Alk5 Inhibition Increases Delivery of Macromolecular and Protein-bound Contrast Agents to Tumors
  JCI Insight. May, 2016  |   Pubmed ID: 27182558
• Distinct Clinical Patterns and Immune Infiltrates Are Observed at Time of Progression on Targeted Therapy Versus Immune Checkpoint Blockade for Melanoma
  Oncoimmunology. Mar, 2016  |   Pubmed ID: 27141370
• The Basis of Oncoimmunology
  Cell. Mar, 2016  |   Pubmed ID: 26967289
• Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer
  Cancer Discovery. Mar, 2016  |   Pubmed ID: 26715645
• Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer
  Cancer Discovery. Jan, 2016  |   Pubmed ID: 26552413
• Senescence and Cancer: An Evolving Inflammatory Paradox
  Biochimica Et Biophysica Acta. Jan, 2016  |   Pubmed ID: 26453912
• Immune Response to Cancer Therapy: Mounting an Effective Antitumor Response and Mechanisms of Resistance
  Trends in Cancer. Sep, 2015  |   Pubmed ID: 26457331
• Myeloid Cells As Targets for Therapy in Solid Tumors
  Cancer Journal (Sudbury, Mass.). Jul-Aug, 2015  |   Pubmed ID: 26222088
• Macrophages and Therapeutic Resistance in Cancer
  Cancer Cell. Apr, 2015  |   Pubmed ID: 25858805
• TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy
  Cancer Immunology Research. May, 2015  |   Pubmed ID: 25716473
• Macrophage IL-10 Blocks CD8+ T Cell-dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells
  Cancer Cell. Nov, 2014  |   Pubmed ID: 25446896
• Duality of the Immune Response in Cancer: Lessons Learned from Skin
  The Journal of Investigative Dermatology. Oct, 2014  |   Pubmed ID: 25302470
• Manipulating MicroRNAs to Regulate Macrophage Polarization in Gliomas
  Journal of the National Cancer Institute. Aug, 2014  |   Pubmed ID: 25136034
• Mammary Gland Involution As an Immunotherapeutic Target for Postpartum Breast Cancer
  Journal of Mammary Gland Biology and Neoplasia. Jul, 2014  |   Pubmed ID: 24952477
• B Cells Regulate Macrophage Phenotype and Response to Chemotherapy in Squamous Carcinomas
  Cancer Cell. Jun, 2014  |   Pubmed ID: 24909985
• A Listeria Vaccine and Depletion of T-regulatory Cells Activate Immunity Against Early Stage Pancreatic Intraepithelial Neoplasms and Prolong Survival of Mice
  Gastroenterology. Jun, 2014  |   Pubmed ID: 24607504
• CSF1R Inhibition Delays Cervical and Mammary Tumor Growth in Murine Models by Attenuating the Turnover of Tumor-associated Macrophages and Enhancing Infiltration by CD8(+) T Cells
  Oncoimmunology. Dec, 2013  |   Pubmed ID: 24498562
• Poker Face No More: Cancer Recurrence Reveals Its Hand
  Nature Medicine. Dec, 2013  |   Pubmed ID: 24309652
• Dendritic Cells, Inflammation, and Breast Cancer
  Cancer Journal (Sudbury, Mass.). Nov-Dec, 2013  |   Pubmed ID: 24270350
• Cathepsin C is a Tissue-specific Regulator of Squamous Carcinogenesis
  Genes & Development. Oct, 2013  |   Pubmed ID: 24065739
• Tumor-infiltrating Regulatory T Cells Inhibit Endogenous Cytotoxic T Cell Responses to Lung Adenocarcinoma
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2013  |   Pubmed ID: 23851682
• Some DCs Are "B"etter
  Immunity. Apr, 2013  |   Pubmed ID: 23601679
• B Cells and Their Mediators As Targets for Therapy in Solid Tumors
  Experimental Cell Research. Jul, 2013  |   Pubmed ID: 23499742
• Neutralizing Tumor-promoting Chronic Inflammation: a Magic Bullet?
  Science (New York, N.Y.). Jan, 2013  |   Pubmed ID: 23329041
• MR Imaging of Tumor-associated Macrophages
  Oncoimmunology. Jul, 2012  |   Pubmed ID: 22754769
• Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
  Cancer Cell. Mar, 2012  |   Pubmed ID: 22439926
• Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy
  Cancer Research. May, 2012  |   Pubmed ID: 22414581
• Differential Macrophage Programming in the Tumor Microenvironment
  Trends in Immunology. Mar, 2012  |   Pubmed ID: 22277903
• Leukocyte Composition of Human Breast Cancer
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012  |   Pubmed ID: 21825174
• Protective Role of Cathepsin L in Mouse Skin Carcinogenesis
  Molecular Carcinogenesis. Apr, 2012  |   Pubmed ID: 21538579
• Immune Microenvironments in Solid Tumors: New Targets for Therapy
  Genes & Development. Dec, 2011  |   Pubmed ID: 22190457
• Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy
  Cancer Discovery. Jun, 2011  |   Pubmed ID: 22039576
• MRI of Tumor-associated Macrophages with Clinically Applicable Iron Oxide Nanoparticles
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011  |   Pubmed ID: 21791632
• B Regulatory Cells and the Tumor-promoting Actions of TNF-α During Squamous Carcinogenesis
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011  |   Pubmed ID: 21670304
• Leukocytes As Paracrine Regulators of Metastasis and Determinants of Organ-specific Colonization
  International Journal of Cancer. Journal International Du Cancer. Jun, 2011  |   Pubmed ID: 21387299
• Histamine Restricts Cancer: Nothing to Sneeze At
  Nature Medicine. Jan, 2011  |   Pubmed ID: 21217680
• Leukocytes in Mammary Development and Cancer
  Cold Spring Harbor Perspectives in Biology. Mar, 2011  |   Pubmed ID: 21123394
• Unimpeded Skin Carcinogenesis in K14-HPV16 Transgenic Mice Deficient for Plasminogen Activator Inhibitor
  International Journal of Cancer. Jan, 2011  |   Pubmed ID: 20232379
• The Tumor-immune Microenvironment and Response to Radiation Therapy
  Journal of Mammary Gland Biology and Neoplasia. Dec, 2010  |   Pubmed ID: 21161342
• Receptor Tyrosine Kinase Signaling Favors a Protumorigenic State in Breast Cancer Cells by Inhibiting the Adaptive Immune Response
  Cancer Research. Oct, 2010  |   Pubmed ID: 20924104
• Macrophage Expression of Hypoxia-inducible Factor-1 Alpha Suppresses T-cell Function and Promotes Tumor Progression
  Cancer Research. Oct, 2010  |   Pubmed ID: 20841473
• Interactions Between Lymphocytes and Myeloid Cells Regulate Pro- Versus Anti-tumor Immunity
  Cancer Metastasis Reviews. Jun, 2010  |   Pubmed ID: 20405169
• Cancer and Inflammation: Promise for Biologic Therapy
  Journal of Immunotherapy (Hagerstown, Md. : 1997). May, 2010  |   Pubmed ID: 20386472
• Stromal Regulation of Vessel Stability by MMP14 and TGFbeta
  Disease Models & Mechanisms. May-Jun, 2010  |   Pubmed ID: 20223936
• FcRgamma Activation Regulates Inflammation-associated Squamous Carcinogenesis
  Cancer Cell. Feb, 2010  |   Pubmed ID: 20138013
• Lymphocytes in Cancer Development: Polarization Towards Pro-tumor Immunity
  Cytokine & Growth Factor Reviews. Feb, 2010  |   Pubmed ID: 20005150
• Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer Vaccines
  US Oncology. 2009  |   Pubmed ID: 22368692
• Optical Imaging of the Peri-tumoral Inflammatory Response in Breast Cancer
  Journal of Translational Medicine. 2009  |   Pubmed ID: 19906309
• Collagen-based Cell Migration Models in Vitro and in Vivo
  Seminars in Cell & Developmental Biology. Oct, 2009  |   Pubmed ID: 19682592
• CD4(+) T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages
  Cancer Cell. Aug, 2009  |   Pubmed ID: 19647220
• Delineating Protease Functions During Cancer Development
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19377975
• Development of an Optimized Activatable MMP-14 Targeted SPECT Imaging Probe
  Bioorganic & Medicinal Chemistry. Jan, 2009  |   Pubmed ID: 19109023
• Inflaming Gastrointestinal Oncogenic Programming
  Cancer Cell. Jul, 2008  |   Pubmed ID: 18598939
• Genetic and Cellular Mechanisms of Oncogenesis
  Current Opinion in Genetics & Development. Feb, 2008  |   Pubmed ID: 18440220
• Polarized Immune Responses Differentially Regulate Cancer Development
  Immunological Reviews. Apr, 2008  |   Pubmed ID: 18363999
• The Initial Steps of Ovarian Cancer Cell Metastasis Are Mediated by MMP-2 Cleavage of Vitronectin and Fibronectin
  The Journal of Clinical Investigation. Apr, 2008  |   Pubmed ID: 18340378
• Immune Cells As Mediators of Solid Tumor Metastasis
  Cancer Metastasis Reviews. Mar, 2008  |   Pubmed ID: 18066650
• Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling
  Cancer Research. Sep, 2007  |   Pubmed ID: 17875701
• Inflammation and Breast Cancer. Balancing Immune Response: Crosstalk Between Adaptive and Innate Immune Cells During Breast Cancer Progression
  Breast Cancer Research : BCR. 2007  |   Pubmed ID: 17705880
• Distinctive Features of Angiogenesis and Lymphangiogenesis Determine Their Functionality During De Novo Tumor Development
  Cancer Research. Jun, 2007  |   Pubmed ID: 17545601
• Hu/Mu ProtIn Oligonucleotide Microarray: Dual-species Array for Profiling Protease and Protease Inhibitor Gene Expression in Tumors and Their Microenvironment
  Molecular Cancer Research : MCR. May, 2007  |   Pubmed ID: 17510311
• Type I Collagen is a Genetic Modifier of Matrix Metalloproteinase 2 in Murine Skeletal Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jun, 2007  |   Pubmed ID: 17440987
• IKKalpha at the Crossroads of Inflammation and Metastasis
  Cell. Apr, 2007  |   Pubmed ID: 17418780
• Humoral Immunity, Inflammation and Cancer
  Current Opinion in Immunology. Apr, 2007  |   Pubmed ID: 17276050
• Immune Cells As Anti-cancer Therapeutic Targets and Tools
  Journal of Cellular Biochemistry. Jul, 2007  |   Pubmed ID: 17265430
• Tumor Stroma and Regulation of Cancer Development
  Annual Review of Pathology. 2006  |   Pubmed ID: 18039110
• Tumor Progression and Metastasis from Genetic to Microenvironmental Determinants: a Workshop of the Tumor Progression and Metastasis NIH Study Section in Honor of Dr. Martin L. Padarathsingh, May 31, 2006, Georgetown, Washington, DC
  Cancer Biology & Therapy. Dec, 2006  |   Pubmed ID: 17224636
• Analysis of Immune Cell Infiltrates During Squamous Carcinoma Development
  The Journal of Investigative Dermatology. Symposium Proceedings. Sep, 2006  |   Pubmed ID: 17069009
• A Selective Activity-based Probe for the Papain Family Cysteine Protease Dipeptidyl Peptidase I/cathepsin C
  Journal of the American Chemical Society. May, 2006  |   Pubmed ID: 16637611
• The Inflammatory Tumor Microenvironment and Its Impact on Cancer Development
  Contributions to Microbiology. 2006  |   Pubmed ID: 16627962
• Inflammation, Proteases and Cancer
  European Journal of Cancer (Oxford, England : 1990). Apr, 2006  |   Pubmed ID: 16524717
• Paradoxical Roles of the Immune System During Cancer Development
  Nature Reviews. Cancer. Jan, 2006  |   Pubmed ID: 16397525
• Three-dimensional Visualization of Blood and Lymphatic Vasculature in Tissue Whole Mounts Using Confocal Microscopy
  Current Protocols in Cytometry. May, 2005  |   Pubmed ID: 18770816
• De Novo Carcinogenesis Promoted by Chronic Inflammation is B Lymphocyte Dependent
  Cancer Cell. May, 2005  |   Pubmed ID: 15894262
• The Contribution of Bone Marrow-derived Cells to the Tumor Vasculature in Neuroblastoma is Matrix Metalloproteinase-9 Dependent
  Cancer Research. Apr, 2005  |   Pubmed ID: 15833851
• Soluble Mediators of Inflammation During Tumor Development
  Advances in Cancer Research. 2005  |   Pubmed ID: 15797447
• Early Neoplastic Progression is Complement Independent
  Neoplasia (New York, N.Y.). Nov-Dec, 2004  |   Pubmed ID: 15720803
• Cancer: an Inflammatory Link
  Nature. Sep, 2004  |   Pubmed ID: 15385993
• Matrix Metalloproteinase-2 and -9 Expression Increases in Mycoplasma-infected Airways but is Not Required for Microvascular Remodeling
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2004  |   Pubmed ID: 15075248
• Stromal Matrix Metalloproteinase-9 Regulates the Vascular Architecture in Neuroblastoma by Promoting Pericyte Recruitment
  Cancer Research. Mar, 2004  |   Pubmed ID: 14996727
• TIMP-1 Alters Susceptibility to Carcinogenesis
  Cancer Research. Feb, 2004  |   Pubmed ID: 14871825
• The Tumor Microenvironment: a Critical Determinant of Neoplastic Evolution
  European Journal of Cell Biology. Nov, 2003  |   Pubmed ID: 14703010
• Immune Enhancement of Skin Carcinogenesis by CD4+ T Cells
  The Journal of Experimental Medicine. Apr, 2003  |   Pubmed ID: 12695493
• Epithelial Carcinogenesis: Dynamic Interplay Between Neoplastic Cells and Their Microenvironment
  Differentiation; Research in Biological Diversity. Dec, 2002  |   Pubmed ID: 12492502
• Inflammation and Cancer
  Nature. Dec 19-26, 2002  |   Pubmed ID: 12490959
• MMP9 Potentiates Pulmonary Metastasis Formation
  Cancer Cell. Oct, 2002  |   Pubmed ID: 12398887
• RECKing MMP Function: Implications for Cancer Development
  Trends in Cell Biology. May, 2002  |   Pubmed ID: 12062160
• Matrix Metalloproteinase Inhibitors and Cancer: Trials and Tribulations
  Science (New York, N.Y.). Mar, 2002  |   Pubmed ID: 11923519