Lonnie D. Shea Institute for BioNanotechnology in Advanced Medicine Northwestern University Biography Publications Institution JoVE Articles Lonnie D. Shea has not added a biography. If you are Lonnie D. Shea and would like to personalize this page please email our Author Liaison for assistance. Publications Embryonic Fibroblasts Enable the Culture of Primary Ovarian Follicles Within Alginate Hydrogels Tissue Engineering. Part A. Feb, 2012 | Pubmed ID: 22296562 Multifunctional, Multichannel Bridges That Deliver Neurotrophin Encoding Lentivirus for Regeneration Following Spinal Cord Injury Biomaterials. Feb, 2012 | Pubmed ID: 22130565 Hydrogel Design for Supporting Neurite Outgrowth and Promoting Gene Delivery to Maximize Neurite Extension Biotechnology and Bioengineering. Mar, 2012 | Pubmed ID: 22038654 Fibrin Hydrogels for Lentiviral Gene Delivery in Vitro and in Vivo Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2012 | Pubmed ID: 21907251 Hydrogels to Modulate Lentivirus Delivery in Vivo from Microporous Tissue Engineering Scaffolds Drug Delivery and Translational Research. Feb, 2011 | Pubmed ID: 22229129 Tissue Engineering Tools for Modulation of the Immune Response BioTechniques. Oct, 2011 | Pubmed ID: 21988690 Extrahepatic Islet Transplantation with Microporous Polymer Scaffolds in Syngeneic Mouse and Allogeneic Porcine Models Biomaterials. Dec, 2011 | Pubmed ID: 21959005 Fibrin Encapsulation and Vascular Endothelial Growth Factor Delivery Promotes Ovarian Graft Survival in Mice Tissue Engineering. Part A. Dec, 2011 | Pubmed ID: 21740332 Vascular Endothelial Growth Factor and Fibroblast Growth Factor 2 Delivery from Spinal Cord Bridges to Enhance Angiogenesis Following Injury Journal of Biomedical Materials Research. Part A. Sep, 2011 | Pubmed ID: 21630429 Engineering Biomaterial Systems to Enhance Viral Vector Gene Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2011 | Pubmed ID: 21629221 Gene Expression in Mouse Ovarian Follicle Development in Vivo Versus an Ex Vivo Alginate Culture System Reproduction (Cambridge, England). Aug, 2011 | Pubmed ID: 21610168 Gene Therapy Vectors with Enhanced Transfection Based on Hydrogels Modified with Affinity Peptides Biomaterials. Aug, 2011 | Pubmed ID: 21514659 Permanent Protection of PLG Scaffold Transplanted Allogeneic Islet Grafts in Diabetic Mice Treated with ECDI-fixed Donor Splenocyte Infusions Biomaterials. Jul, 2011 | Pubmed ID: 21458857 Hydrogel Network Design Using Multifunctional Macromers to Coordinate Tissue Maturation in Ovarian Follicle Culture Biomaterials. Apr, 2011 | Pubmed ID: 21247629 In Vitro Oocyte Maturation and Preantral Follicle Culture from the Luteal-phase Baboon Ovary Produce Mature Oocytes Biology of Reproduction. Apr, 2011 | Pubmed ID: 21123815 A New Hypothesis Regarding Ovarian Follicle Development: Ovarian Rigidity As a Regulator of Selection and Health Journal of Assisted Reproduction and Genetics. Jan, 2011 | Pubmed ID: 20872066 Cellular Arrays for Large-scale Analysis of Transcription Factor Activity Biotechnology and Bioengineering. Feb, 2011 | Pubmed ID: 20812256 Dynamic, Large-scale Profiling of Transcription Factor Activity from Live Cells in 3D Culture PloS One. 2010 | Pubmed ID: 21103341 To Transplant or Not to Transplant - That is the Question Cancer Treatment and Research. 2010 | Pubmed ID: 20811824 Designing Follicle-environment Interactions with Biomaterials Cancer Treatment and Research. 2010 | Pubmed ID: 20811822 Microenvironmental Regulation of Chemokine (C-X-C-motif) Receptor 4 in Ovarian Carcinoma Molecular Cancer Research : MCR. May, 2010 | Pubmed ID: 20460402 Balancing Cell Migration with Matrix Degradation Enhances Gene Delivery to Cells Cultured Three-dimensionally Within Hydrogels Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2010 | Pubmed ID: 20450944 Phosphatidylserine Immobilization of Lentivirus for Localized Gene Transfer Biomaterials. May, 2010 | Pubmed ID: 20206382 Noninvasive Index of Cryorecovery and Growth Potential for Human Follicles in Vitro Biology of Reproduction. Jun, 2010 | Pubmed ID: 20200211 Patterned Transgene Expression in Multiple-channel Bridges After Spinal Cord Injury Acta Biomaterialia. Aug, 2010 | Pubmed ID: 20167291 Markers of Growth and Development in Primate Primordial Follicles Are Preserved After Slow Cryopreservation Fertility and Sterility. May, 2010 | Pubmed ID: 20074723 Lentivirus Immobilization to Nanoparticles for Enhanced and Localized Delivery from Hydrogels Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2010 | Pubmed ID: 20051940 A Novel Two-step Strategy for in Vitro Culture of Early-stage Ovarian Follicles in the Mouse Fertility and Sterility. May, 2010 | Pubmed ID: 20004373 The Contribution of Plasmid Design and Release to in Vivo Gene Expression Following Delivery from Cationic Polymer Modified Scaffolds Biomaterials. Feb, 2010 | Pubmed ID: 19892398 Lentivirus Delivery by Adsorption to Tissue Engineering Scaffolds Journal of Biomedical Materials Research. Part A. Jun, 2010 | Pubmed ID: 19827108 Stem/progenitor Cell-mediated De Novo Regeneration of Dental Pulp with Newly Deposited Continuous Layer of Dentin in an in Vivo Model Tissue Engineering. Part A. Feb, 2010 | Pubmed ID: 19737072 Engineering Surfaces for Substrate-mediated Gene Delivery Using Recombinant Proteins Biomacromolecules. Oct, 2009 | Pubmed ID: 19775146 Interpenetrating Fibrin-alginate Matrices for in Vitro Ovarian Follicle Development Biomaterials. Oct, 2009 | Pubmed ID: 19616843 In Vitro Grown Human Ovarian Follicles from Cancer Patients Support Oocyte Growth Human Reproduction (Oxford, England). Oct, 2009 | Pubmed ID: 19597190 Encapsulated Three-dimensional Culture Supports Development of Nonhuman Primate Secondary Follicles Biology of Reproduction. Sep, 2009 | Pubmed ID: 19474063 Multiple Channel Bridges for Spinal Cord Injury: Cellular Characterization of Host Response Tissue Engineering. Part A. Nov, 2009 | Pubmed ID: 19382871 Downregulation of Connective Tissue Growth Factor by Three-dimensional Matrix Enhances Ovarian Carcinoma Cell Invasion International Journal of Cancer. Journal International Du Cancer. Aug, 2009 | Pubmed ID: 19382180 Non-viral Gene Delivery Transfection Profiles Influence Neuronal Architecture in an in Vitro Co-culture Model Biotechnology and Bioengineering. Aug, 2009 | Pubmed ID: 19309756 Preserving Female Fertility Following Cancer Treatment: Current Options and Future Possibilities Pediatric Blood & Cancer. Aug, 2009 | Pubmed ID: 19301373 Fibrin Hydrogels for Non-viral Vector Delivery in Vitro Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2009 | Pubmed ID: 19232532 Sustained Transgene Expression Via Citric Acid-based Polyester Elastomers Biomaterials. May, 2009 | Pubmed ID: 19200593 Secondary Follicle Growth and Oocyte Maturation by Culture in Alginate Hydrogel Following Cryopreservation of the Ovary or Individual Follicles Biotechnology and Bioengineering. Jun, 2009 | Pubmed ID: 19191350 Efficacy of Immobilized Polyplexes and Lipoplexes for Substrate-mediated Gene Delivery Biotechnology and Bioengineering. Apr, 2009 | Pubmed ID: 19148921 Local Gene Delivery from ECM-coated Poly(lactide-co-glycolide) Multiple Channel Bridges After Spinal Cord Injury Biomaterials. Apr, 2009 | Pubmed ID: 19144400 Plasmid Releasing Multiple Channel Bridges for Transgene Expression After Spinal Cord Injury Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2009 | Pubmed ID: 19050701 The Mouse Follicle Microenvironment Regulates Antrum Formation and Steroid Production: Alterations in Gene Expression Profiles Biology of Reproduction. Mar, 2009 | Pubmed ID: 19005169 Self-assembling Peptide-lipoplexes for Substrate-mediated Gene Delivery Acta Biomaterialia. Mar, 2009 | Pubmed ID: 18990615 Spatially Patterned Gene Expression for Guided Neurite Extension Journal of Neuroscience Research. Mar, 2009 | Pubmed ID: 18951499 Layered PLG Scaffolds for in Vivo Plasmid Delivery Biomaterials. Jan, 2009 | Pubmed ID: 18929408 Extracellular Matrix Protein-coated Scaffolds Promote the Reversal of Diabetes After Extrahepatic Islet Transplantation Transplantation. May, 2008 | Pubmed ID: 18497687 Motility-related Actinin Alpha-4 is Associated with Advanced and Metastatic Ovarian Carcinoma Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2008 | Pubmed ID: 18362906 Peptide-mediated Lipofection is Governed by Lipoplex Physical Properties and the Density of Surface-displayed Amines Journal of Pharmaceutical Sciences. Nov, 2008 | Pubmed ID: 18306277 Wilms Tumor Gene Protein 1 is Associated with Ovarian Cancer Metastasis and Modulates Cell Invasion Cancer. Apr, 2008 | Pubmed ID: 18260155 Surface Polyethylene Glycol Enhances Substrate-mediated Gene Delivery by Nonspecifically Immobilized Complexes Acta Biomaterialia. Jan, 2008 | Pubmed ID: 17920004 The Role of the Extracellular Matrix in Ovarian Follicle Development Reproductive Sciences (Thousand Oaks, Calif.). Dec, 2007 | Pubmed ID: 18089604 Bioengineering and the Ovarian Follicle Cancer Treatment and Research. 2007 | Pubmed ID: 18080658 Physical Properties of Alginate Hydrogels and Their Effects on in Vitro Follicle Development Biomaterials. Oct, 2007 | Pubmed ID: 17643486 Engineering the Follicle Microenvironment Seminars in Reproductive Medicine. Jul, 2007 | Pubmed ID: 17594609 Non-viral Vector Delivery from PEG-hyaluronic Acid Hydrogels Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2007 | Pubmed ID: 17582640 Regulation and Guidance of Cell Behavior for Tissue Regeneration Via the SiRNA Mechanism Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. May-Jun, 2007 | Pubmed ID: 17537114 Gene Expression and Internalization Following Vector Adsorption to Immobilized Proteins: Dependence on Protein Identity and Density The Journal of Gene Medicine. Aug, 2007 | Pubmed ID: 17533618 Matrices and Scaffolds for DNA Delivery in Tissue Engineering Advanced Drug Delivery Reviews. May, 2007 | Pubmed ID: 17512630 Bioluminescence Imaging for Assessment and Normalization in Transfected Cell Arrays Biotechnology and Bioengineering. Oct, 2007 | Pubmed ID: 17486653 Patterned PLG Substrates for Localized DNA Delivery and Directed Neurite Extension Biomaterials. Jun, 2007 | Pubmed ID: 17324456 Spatially Patterned Gene Delivery for Localized Neuron Survival and Neurite Extension Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2007 | Pubmed ID: 17299403 The Structures That Underlie Normal Reproductive Function Molecular and Cellular Endocrinology. Mar, 2007 | Pubmed ID: 17140726 Tissue-engineered Follicles Produce Live, Fertile Offspring Tissue Engineering. Oct, 2006 | Pubmed ID: 17518643 Back to the Science of Stem Cell Research - CHI's 2nd Annual Meeting IDrugs : the Investigational Drugs Journal. Oct, 2006 | Pubmed ID: 17016776 Identification of a Stage-specific Permissive in Vitro Culture Environment for Follicle Growth and Oocyte Development Biology of Reproduction. Dec, 2006 | Pubmed ID: 16957022 Extracellular Matrix Functions in Follicle Maturation Seminars in Reproductive Medicine. Sep, 2006 | Pubmed ID: 16944423 Postnatal Regulation of Germ Cells by Activin: the Establishment of the Initial Follicle Pool Developmental Biology. Oct, 2006 | Pubmed ID: 16930587 Polymer Scaffolds As Synthetic Microenvironments for Extrahepatic Islet Transplantation Transplantation. Aug, 2006 | Pubmed ID: 16926587 Fate of the Initial Follicle Pool: Empirical and Mathematical Evidence Supporting Its Sufficiency for Adult Fertility Developmental Biology. Oct, 2006 | Pubmed ID: 16925987 Inductive Tissue Engineering with Protein and DNA-releasing Scaffolds Molecular BioSystems. Jan, 2006 | Pubmed ID: 16880921 Distribution of Extracellular Matrix Proteins Type I Collagen, Type IV Collagen, Fibronectin, and Laminin in Mouse Folliculogenesis Histochemistry and Cell Biology. Nov, 2006 | Pubmed ID: 16758163 Cancer Survivors and Infertility: a Review of a New Problem and Novel Answers The Journal of Supportive Oncology. Apr, 2006 | Pubmed ID: 16669459 Intramuscular Delivery of DNA Releasing Microspheres: Microsphere Properties and Transgene Expression Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2006 | Pubmed ID: 16530876 Surface Adsorption of DNA to Tissue Engineering Scaffolds for Efficient Gene Delivery Journal of Biomedical Materials Research. Part A. Apr, 2006 | Pubmed ID: 16353173 Nerve Growth Factor Expression by PLG-mediated Lipofection Biomaterials. Apr, 2006 | Pubmed ID: 16316681 Design of Modular Non-viral Gene Therapy Vectors Biomaterials. Mar, 2006 | Pubmed ID: 16243391 The in Vitro Regulation of Ovarian Follicle Development Using Alginate-extracellular Matrix Gels Biomaterials. Feb, 2006 | Pubmed ID: 16076485 Gene Delivery by Immobilization to Cell-Adhesive Substrates MRS Bulletin / Materials Research Society. Sep, 2005 | Pubmed ID: 19319206 Substrate-mediated Delivery from Self-assembled Monolayers: Effect of Surface Ionization, Hydrophilicity, and Patterning Acta Biomaterialia. Sep, 2005 | Pubmed ID: 16701831 Regulation of Mouse Follicle Development by Follicle-stimulating Hormone in a Three-dimensional in Vitro Culture System is Dependent on Follicle Stage and Dose Biology of Reproduction. Nov, 2005 | Pubmed ID: 15987824 Plasmid Delivery in Vivo from Porous Tissue-engineering Scaffolds: Transgene Expression and Cellular Transfection Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2005 | Pubmed ID: 15950542 Neurotrophin Releasing Single and Multiple Lumen Nerve Conduits Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2005 | Pubmed ID: 15911044 Gene Delivery Through Cell Culture Substrate Adsorbed DNA Complexes Biotechnology and Bioengineering. May, 2005 | Pubmed ID: 15800863 DNA Delivery from Hyaluronic Acid-collagen Hydrogels Via a Substrate-mediated Approach Biomaterials. May, 2005 | Pubmed ID: 15522759 Crosslinked Hyaluronic Acid Hydrogels: a Strategy to Functionalize and Pattern Biomaterials. Feb, 2005 | Pubmed ID: 15275810 Gene Delivery from Polymer Scaffolds for Tissue Engineering Expert Review of Medical Devices. Sep, 2004 | Pubmed ID: 16293016 Delivery Systems for Small Molecule Drugs, Proteins, and DNA: the Neuroscience/biomaterial Interface Experimental Neurology. Nov, 2004 | Pubmed ID: 15473976 Modular Design of Non-viral Vectors with Bioactive Components Trends in Biotechnology. Sep, 2004 | Pubmed ID: 15331218 Controlled Release Systems for DNA Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2004 | Pubmed ID: 15233938 Novel Approach for the Three-dimensional Culture of Granulosa Cell-oocyte Complexes Tissue Engineering. Oct, 2003 | Pubmed ID: 14633385 Substrate-mediated DNA Delivery: Role of the Cationic Polymer Structure and Extent of Modification Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2003 | Pubmed ID: 14602423 Murine Granulosa Cell Morphology and Function Are Regulated by a Synthetic Arg-Gly-Asp Matrix Molecular and Cellular Endocrinology. Jul, 2003 | Pubmed ID: 12890562 Controllable Delivery of Non-viral DNA from Porous Scaffolds Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2003 | Pubmed ID: 12490381 Surface-tethered DNA Complexes for Enhanced Gene Delivery Bioconjugate Chemistry. May-Jun, 2002 | Pubmed ID: 12009954 Drug-releasing Scaffolds Fabricated from Drug-loaded Microspheres Journal of Biomedical Materials Research. Feb, 2002 | Pubmed ID: 11745572 डिम्बग्रंथि कूप और एक Proteolytically सड़ सकने 3 आयामी प्रणाली में इनकैप्सुलेशन संस्कृति के लिए एक विधि Ariella Shikanov1, Min Xu2, Teresa K. Woodruff2,3,4, Lonnie D. Shea1,4,5 1Institute for BioNanotechnology in Advanced Medicine, Northwestern University, 2Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, 3Center for Reproductive Research, Northwestern University, 4The Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 5Department of Chemical and Biological Engineering, Northwestern University JoVE 2695 Bioengineering
डिम्बग्रंथि कूप और एक Proteolytically सड़ सकने 3 आयामी प्रणाली में इनकैप्सुलेशन संस्कृति के लिए एक विधि Ariella Shikanov1, Min Xu2, Teresa K. Woodruff2,3,4, Lonnie D. Shea1,4,5 1Institute for BioNanotechnology in Advanced Medicine, Northwestern University, 2Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, 3Center for Reproductive Research, Northwestern University, 4The Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 5Department of Chemical and Biological Engineering, Northwestern University JoVE 2695 Bioengineering